Zoe, League of Legends champion
Win Rate
46.9%
Pick Rate
1.6%
Ban Rate
2.2%

Zoe Mid Runes: Keystone & Shards

Zoe F TierMage
Patch
26.20
Games
3,163
Lane
Mid
Tier
All Tiers
Last Updated
Oct 22, 2026 UTC
Methodology
Data Methodology

Best Mid Zoe runes for LoL Patch 26.20 - Electrocute from the Domination tree with Sorcery secondary (62.2% WR, 1.4% pick rate). Zoe's optimal primary runes are Electrocute, Taste of Blood, Grisly Mementos, Relentless Hunter. Secondary tree: Scorch, Nimbus Cloak.

Zoe performs best with Electrocute as the keystone rune from the Domination tree. Zoe's optimal primary runes are Electrocute, Taste of Blood, Grisly Mementos, Relentless Hunter. Zoe's secondary rune tree is Sorcery with Scorch, Nimbus Cloak. This rune setup achieves a 62.22% win rate (+15.3% win rate difference) with a 1.4% pick rate across 45 Zoe games.
62.2%Win Rate
+15.3%WR Diff
1.4%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Taste of BloodTaste of Blood

Heal when you damage an enemy champion.

Healing: 16-40 (+0.1 bonus AD, +0.05 AP) health (based on level)

Cooldown: 20s

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Nimbus CloakNimbus Cloak

After casting a Summoner Spell, gain a Move Speed increase that lasts for 2s and allows you to pass through units.

Increase: 15% - 45% Move Speed based on the Summoner Spell's cooldown. (Higher cooldown Summoner Spells grant more Move Speed).

This alternative Zoe rune build uses Electrocute as the keystone from the Domination tree. The primary runes are Electrocute, Sudden Impact, Grisly Mementos, Relentless Hunter. Zoe's secondary rune tree is Sorcery with Transcendence, Nimbus Cloak. This setup achieves a 70.59% win rate (+23.7% win rate difference) with a 0.5% pick rate across 17 games.
70.6%Win Rate
+23.7%WR Diff
0.5%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Sudden ImpactSudden Impact

Damaging basic attacks and abilities deal a bonus 20 - 80 True Damage based on level to enemy champions after using a dash, leap, blink, teleport, or when leaving stealth for 4s.

Cooldown: 10s

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

Nimbus CloakNimbus Cloak

After casting a Summoner Spell, gain a Move Speed increase that lasts for 2s and allows you to pass through units.

Increase: 15% - 45% Move Speed based on the Summoner Spell's cooldown. (Higher cooldown Summoner Spells grant more Move Speed).

These champions share at least 4 runes with Zoe's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Zoe's playstyle or want to learn champions with familiar rune setups.LeBlanc, Katarina, Kennen, Anivia, Sylas and 1 other

Every Zoe Mid Keystone and Secondary Tree (Patch 26.20)

3,044 games

Zoe Mid runs Electrocute in 65% of games, with a 46.7% win rate. Sorcery is the usual secondary tree (79%). Standard stat shards: Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
ElectrocuteElectrocuteMost played65.0%46.7%1,980
Dark HarvestDark Harvest28.2%45.9%857
Summon AerySummon Aery4.6%56.7%141

Secondary trees

RunePlayersWin RateGames
SorcerySorceryMost played78.9%46.8%2,402
PrecisionPrecision16.6%46.5%505
DominationDomination1.9%45.8%59
InspirationInspiration1.3%48.8%41

Pick rate is the share of Zoe games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Zoe Minor Runes by Tree

Every minor rune Zoe players take, grouped by rune tree, with how often it is picked and how often it wins.

Domination

RunePlayersWin RateGames
Grisly MementosGrisly MementosMost played89.5%46.2%2,723
Relentless HunterRelentless Hunter87.9%46.4%2,676
Sudden ImpactSudden Impact68.0%45.7%2,071
Taste of BloodTaste of Blood21.7%47.0%662
Cheap ShotCheap Shot5.3%54.4%160
Treasure HunterTreasure Hunter4.2%44.9%127

Sorcery

RunePlayersWin RateGames
Nimbus CloakNimbus CloakMost played76.4%46.7%2,325
TranscendenceTranscendence66.5%45.8%2,024
ScorchScorch17.2%50.5%525
Gathering StormGathering Storm5.3%52.2%161
Manaflow BandManaflow Band4.8%47.3%146
CelerityCelerity3.9%52.1%119

Precision

RunePlayersWin RateGames
Legend: HasteLegend: HasteMost played15.5%46.1%471
Cut DownCut Down14.5%46.3%441
Presence of MindPresence of Mind2.0%47.5%61

Zoe Stat Shards

Which stat shards Zoe players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex)Adaptive Force (flex)Most played96.7%46.5%2,943
Attack Speed (offense)Attack Speed (offense)88.9%46.4%2,705
Health Scaling (defense)Health Scaling (defense)69.6%46.5%2,118
Health (defense)Health (defense)25.9%47.0%788
Adaptive Force (offense)Adaptive Force (offense)8.9%49.4%271
Tenacity and Slow Resist (defense)Tenacity and Slow Resist (defense)4.5%49.3%138
Move Speed (flex)Move Speed (flex)2.9%53.4%88
Ability Haste (offense)Ability Haste (offense)2.2%48.5%68
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Zoe Runes FAQ - Patch 26.20

What is the best keystone for Zoe Mid?

Electrocute: Zoe Mid takes it in 65% of ranked games and wins 46.7% of 1,980 games. Alternatives: Dark Harvest (28%, 45.9%), Summon Aery (5%, 56.7%).

What stat shards should Zoe take?

Most Zoe players take Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Zoe runes in patch 26.20?

The best Zoe runes in patch 26.20 use the Domination tree with Electrocute, Taste of Blood, Grisly Mementos, and Relentless Hunter, and the Sorcery tree with Scorch and Nimbus Cloak. This rune setup achieves a 62.2% win rate with a 1.4% pick rate.

What is the win rate for Zoe's best rune page?

Zoe's best rune page has a 62.2% win rate in patch 26.20, which is +15.3% compared to Zoe's average win rate. This rune setup has a 1.4% pick rate among Zoe players.

What keystone should I use on Zoe?

Electrocute from the Domination tree is the best keystone rune for Zoe in patch 26.20. This keystone synergizes well with Zoe's kit and provides a 62.2% win rate.

What is Zoe's primary rune tree?

Zoe's primary rune tree is Domination. The optimal Domination runes for Zoe are Electrocute, Taste of Blood, Grisly Mementos, and Relentless Hunter, with Electrocute being the keystone of choice.

What is Zoe's secondary rune tree?

Zoe's best secondary rune tree is Sorcery. The recommended Sorcery runes are Scorch and Nimbus Cloak, which complement Zoe's Domination primary tree.

What are alternative rune setups for Zoe?

An alternative Zoe rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Zoe's runes?

Zoe's top rune page has a 1.4% pick rate in patch 26.20. This indicates that 1.4% of Zoe players use the Electrocute setup with Domination and Sorcery trees.