Zoe - League of Legends Champion
Win Rate
50.4%
Pick Rate
1.9%

ZoeRunes

BMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Best Zoe runes for LoL Patch 26.7 - Dark Harvest from the Domination tree with Sorcery secondary (66.7% WR, 0.5% pick rate). Zoe's optimal primary runes are Dark Harvest, Sudden Impact, Grisly Mementos, Treasure Hunter. Secondary tree: Manaflow Band, Celerity.

Zoe performs best with Dark Harvest as the keystone rune from the Domination tree. Zoe's optimal primary runes are Dark Harvest, Sudden Impact, Grisly Mementos, Treasure Hunter. Zoe's secondary rune tree is Sorcery with Manaflow Band, Celerity. This rune setup achieves a 66.67% win rate (+16.2% win rate difference) with a 0.5% pick rate across 18 Zoe games.
66.7%Win Rate
+16.2%WR Diff
0.5%Pick Rate
Dark HarvestDark Harvest

Damaging a Champion below 50% health deals adaptive damage and harvests their soul, permanently increasing Dark Harvest's damage by 11.

Dark Harvest damage: 30 (+11 damage per soul) (+0.1 bonus AD) (+0.05 AP)
Cooldown: 35s (resets to 1.0s on takedown)

Sudden ImpactSudden Impact

Damaging basic attacks and abilities deal a bonus 20 - 80 True Damage based on level to enemy champions after using a dash, leap, blink, teleport, or when leaving stealth for 4s.

Cooldown: 10s

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Treasure HunterTreasure Hunter

Gain an additional 50 gold the next time you collect a Bounty Hunter stack. Increase the gold gained by 20 gold for each Bounty Hunter stack, up to 130 gold.

Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

CelerityCelerity

All movement bonuses are 7% more effective on you and gain 1% Move Speed.

This alternative Zoe rune build uses Electrocute as the keystone from the Domination tree. The primary runes are Electrocute, Taste of Blood, Grisly Mementos, Relentless Hunter. Zoe's secondary rune tree is Sorcery with Celerity, Scorch. This setup achieves a 64.00% win rate (+13.6% win rate difference) with a 0.7% pick rate across 25 games.
64.0%Win Rate
+13.6%WR Diff
0.7%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Taste of BloodTaste of Blood

Heal when you damage an enemy champion.

Healing: 16-40 (+0.1 bonus AD, +0.05 AP) health (based on level)

Cooldown: 20s

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

CelerityCelerity

All movement bonuses are 7% more effective on you and gain 1% Move Speed.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

These champions share at least 4 runes with Zoe's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Zoe's playstyle or want to learn champions with familiar rune setups.LeBlanc, Aurora, Graves, Galio, Gragas

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Zoe Runes - Frequently Asked Questions

What are the best Zoe runes in patch 26.7?

The best Zoe runes in patch 26.7 use the Domination tree with Dark Harvest, Sudden Impact, Grisly Mementos, and Treasure Hunter, and the Sorcery tree with Manaflow Band and Celerity. This rune setup achieves a 66.7% win rate with a 0.5% pick rate.

What is the win rate for Zoe's best rune page?

Zoe's best rune page has a 66.7% win rate in patch 26.7, which is +16.2% compared to Zoe's average win rate. This rune setup has a 0.5% pick rate among Zoe players.

What keystone should I use on Zoe?

Dark Harvest from the Domination tree is the best keystone rune for Zoe in patch 26.7. This keystone synergizes well with Zoe's kit and provides a 66.7% win rate.

What is Zoe's primary rune tree?

Zoe's primary rune tree is Domination. The optimal Domination runes for Zoe are Dark Harvest, Sudden Impact, Grisly Mementos, and Treasure Hunter, with Dark Harvest being the keystone of choice.

What is Zoe's secondary rune tree?

Zoe's best secondary rune tree is Sorcery. The recommended Sorcery runes are Manaflow Band and Celerity, which complement Zoe's Domination primary tree.

What are alternative rune setups for Zoe?

An alternative Zoe rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Zoe's runes?

Zoe's top rune page has a 0.5% pick rate in patch 26.7. This indicates that 0.5% of Zoe players use the Dark Harvest setup with Domination and Sorcery trees.