Zyra - League of Legends Champion
Win Rate
50.5%
Pick Rate
2.6%

Zyravs Sett

BMageSupport
Patch26.10
Matches1,009,027
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Zyra vs Sett is a decisive matchup in LoL patch 26.10. Sett wins with a 60.0% win rate (+20.0%) over Zyra based on 5 games. Zyra wins the early laning phase while Sett scales better into the late game. Below you'll find the best Zyra build, runes, laning stats, and strategies for the Zyra vs Sett matchup.

Zyra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zyra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Sett - 40.0% win rateSett(40.0%)
Zyra - 40.0% win rate in this matchup
Zyra
40.0% WR
VS
Sett vs Zyra matchup - 60.0% win rate
Sett
60.0% WR

Who Wins the Zyra vs Sett Matchup?

Sett wins the Zyra vs Sett matchup
Winner
Sett
Matches: 5
40.0%
Win Rate
60.0%
2.8
CS / min
2.6
868
DMG / min
672
7,833
Gold / game
8,692
72
Heal / min
125
323
DMG Mitigated / min
1,121
2.3
CC / min
0.8
66.7%
Early Game WR
33.3%
0.0%
Late Game WR
100.0%

Zyra vs Sett Matchup Summary

The Zyra vs Sett matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Sett wins with a 60.0% win rate compared to Zyra's 40.0%, giving Sett a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Zyra controls the early laning stage, but Sett outscales as the game goes longer. The matchup shifts dramatically depending on game length — Zyra needs to press advantages before Sett reaches their power spikes, while Sett should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Sett leads by 850 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Sett has a strong advantage in this matchup. Zyra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Sett overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zyra vs Sett Laning Phase Breakdown

Zyra wins the laning phase against Sett in League of Legends

Zyra is favored during the laning phase against Sett, winning 3 out of 5 key stat categories. Zyra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
2.8Zyra
2.6Sett
Zyra and Sett farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
868Zyra
672Sett
Zyra heavily out-damages Sett by 196 DMG/min, dominating both short trades and all-in fights. Sett should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zyra's sustained damage advantage take over.
Economy
7,833Zyra
8,692Sett
Sett generates a commanding 858 more gold per game than Zyra. This substantial economic advantage means Sett consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Zyra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
2.3Zyra
0.8Sett
Zyra brings significantly more crowd control than Sett, with 1.4 more seconds of CC per minute. This large utility gap makes Zyra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Sett should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
395Zyra
1,245Sett
Sett vastly out-sustains Zyra, healing and mitigating 850 more damage per minute. This massive durability gap means Sett can absorb significant punishment and remain in lane while Zyra is forced to recall. Building grievous wounds early is essential for Zyra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zyra Build Against Sett

Ionian Boots of Lucidity is the optimal boots choice against Sett, providing the mobility and stats Zyra needs most in this matchup. The top-performing core items for Zyra against Sett are Liandry's Torment, Zhonya's Hourglass and Rylai's Crystal Scepter. This combination gives Zyra an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zyra vs Sett matchup.

Early Game vs Late Game

Early Game
Zyra
66.7%
+33.3% advantage
Zyra early game win rateZyra66.7%
Sett early game win rateSett33.3%
Late Game
Sett
100.0%
+100.0% advantage
Zyra late game win rateZyra0.0%
Sett late game win rateSett100.0%

Zyra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Sett. This lopsided early game means Zyra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Sett is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Zyra. Extended games heavily favor Sett, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Zyra must aggressively press their early advantage and close out the game before Sett reaches their scaling breakpoints. If Sett survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Zyra Runes Against Sett

Domination rune tree - Zyra primary runes vs SettDomination
Electrocute - best Zyra rune vs SettCheap Shot - best Zyra rune vs SettGrisly Mementos - best Zyra rune vs SettUltimate Hunter - best Zyra rune vs Sett
Sorcery rune tree - Zyra secondary runes vs SettSorcery
Manaflow Band - best Zyra rune vs SettTranscendence - best Zyra rune vs Sett
100.0% WR

The Domination and Sorcery rune setup gives Zyra the best tools to compete against Sett in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Zyra matchup data for League of Legends patch 26.10. The table below shows Zyra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zyra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zyra matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.61%3552.07719,81349.2%46.7%
50.00%2602.072910,18848.3%50.9%
45.12%2151.87549,55450.6%41.7%
42.71%1992.07809,66749.3%38.7%
49.22%1931.87829,72045.0%52.2%
54.45%1912.078010,03758.6%52.1%
53.89%1671.87439,54356.5%52.0%
55.09%1671.97769,81960.9%51.5%
46.25%1602.185910,94843.5%47.4%
44.19%1291.97429,30744.2%44.2%
53.17%1261.97799,70957.8%50.6%
48.39%1241.87079,54754.0%44.6%
44.35%1241.97539,81547.9%42.1%
50.00%962.27299,90451.6%49.2%
65.59%931.66989,33965.0%66.0%
62.64%912.38609,79767.5%58.8%
55.56%901.86228,51961.0%51.0%
45.98%871.97179,77852.9%41.5%
41.18%851.88289,89550.0%35.3%
53.57%841.87829,26164.3%42.9%
54.76%842.57349,90960.6%51.0%
55.00%801.67628,96646.0%62.8%
60.00%701.990210,35264.0%57.8%
46.15%651.979410,14133.3%53.7%
53.97%632.377510,32640.0%63.2%
47.62%631.774811,14957.1%42.9%
55.17%581.87079,73857.9%53.9%
40.74%541.98159,28345.5%37.5%
62.26%532.17979,68454.2%69.0%
51.16%431.97649,13655.6%48.0%
57.14%421.88169,53063.2%52.2%
48.78%411.88369,18346.7%50.0%
57.50%402.883510,87342.9%65.4%
51.28%395.797011,82230.8%61.5%
58.97%391.281612,64575.0%47.8%
69.44%361.879110,25766.7%70.8%
54.29%352.478110,76960.0%52.0%
55.88%341.381012,54464.7%47.1%
57.58%333.276110,04371.4%47.4%
45.45%331.383112,91550.0%42.1%
56.25%322.082510,90577.8%47.8%
46.88%321.385611,53045.5%47.6%
36.67%301.494014,48450.0%31.8%
58.62%291.694611,63687.5%47.6%
55.17%291.77348,69353.3%57.1%
57.14%282.980811,55360.0%53.9%
57.69%261.292712,18950.0%64.3%
46.15%261.67909,87646.1%46.1%
65.38%264.31,12312,48971.4%63.2%
60.00%253.391810,62453.9%66.7%
50.00%245.782610,08633.3%66.7%
62.50%241.483113,75857.1%64.7%
60.87%232.27179,58680.0%55.6%
45.45%221.786912,01137.5%50.0%
40.91%221.881711,50225.0%50.0%
40.91%225.886210,95640.0%41.7%
45.45%224.085911,31242.9%46.7%
40.91%221.584312,15245.5%36.4%
47.62%211.678510,76357.1%42.9%
52.38%213.380611,26033.3%55.6%
55.00%204.31,03012,94266.7%50.0%
65.00%201.883311,92475.0%62.5%
47.37%193.072211,81844.4%50.0%
47.37%192.986210,49020.0%57.1%
52.63%194.78439,98944.4%60.0%
47.06%176.294010,66830.0%71.4%
41.18%173.283710,95166.7%27.3%
52.94%173.889610,37166.7%50.0%
66.67%151.71,01414,14375.0%63.6%
46.67%154.694710,95116.7%66.7%
53.33%154.986011,75150.0%55.6%
60.00%151.488913,30583.3%44.4%
46.67%151.388811,53242.9%50.0%
64.29%142.66869,68666.7%62.5%
71.43%145.290111,11471.4%71.4%
46.15%131.178811,08042.9%50.0%
53.85%131.469610,10637.5%80.0%
38.46%133.47369,98433.3%42.9%
69.23%135.677910,28042.9%100.0%
46.15%136.396812,99333.3%50.0%
69.23%131.57908,88283.3%57.1%
50.00%121.089313,59350.0%50.0%
75.00%121.396614,62366.7%77.8%
41.67%122.682812,409100.0%30.0%
45.45%111.284313,89550.0%44.4%
63.64%111.882512,106100.0%42.9%
45.45%114.88499,93320.0%66.7%
45.45%111.77499,35060.0%33.3%
72.73%111.787712,74560.0%83.3%
63.64%115.579511,83550.0%80.0%
54.55%112.798511,39150.0%60.0%
63.64%115.61,06012,84966.7%62.5%
20.00%101.87389,91525.0%16.7%
60.00%105.28978,17480.0%40.0%
50.00%102.383111,75080.0%20.0%
50.00%105.396511,13266.7%42.9%
66.67%92.287913,5720.0%75.0%
66.67%91.590214,83366.7%66.7%
33.33%91.582910,5790.0%75.0%
22.22%96.41,03212,66314.3%50.0%
55.56%95.681610,70866.7%50.0%
62.50%81.480914,205100.0%40.0%
62.50%84.098513,13175.0%50.0%
75.00%81.896312,338100.0%71.4%
50.00%84.31,02814,92666.7%40.0%
37.50%86.17929,33133.3%40.0%
25.00%81.374211,95233.3%20.0%
37.50%85.61,00011,7320.0%50.0%
42.86%72.290312,3370.0%75.0%
85.71%71.792412,407100.0%80.0%
85.71%72.872910,36666.7%100.0%
57.14%76.696110,71660.0%50.0%
42.86%74.57387,39340.0%50.0%
42.86%75.46179,60833.3%50.0%
71.43%74.37179,860100.0%60.0%
66.67%64.295811,00250.0%75.0%
50.00%65.31,12813,99150.0%50.0%
33.33%61.881410,7760.0%40.0%
33.33%62.795913,949100.0%20.0%
16.67%61.487410,1640.0%25.0%
33.33%65.292610,4520.0%40.0%
66.67%64.975311,20766.7%66.7%
50.00%62.079911,07750.0%50.0%
20.00%55.686411,55150.0%0.0%
60.00%50.885012,69466.7%50.0%
60.00%56.081110,32375.0%0.0%
60.00%51.173912,06566.7%50.0%
60.00%51.61,03210,28966.7%50.0%
40.00%52.88687,83366.7%0.0%
60.00%55.592210,879100.0%33.3%
0.00%53.195212,3040.0%0.0%
20.00%55.298613,4670.0%25.0%

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Zyra vs Sett - Frequently Asked Questions

How does Zyra do against Sett in League of Legends?

Sett wins the Zyra vs Sett matchup with a 60.0% win rate compared to Zyra's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Zyra do against Sett in the early game?

In the early game, Zyra has the advantage against Sett with a 66.7% win rate versus 33.3%. Zyra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zyra do against Sett in the late game?

In the late game, Sett takes over the Zyra vs Sett matchup with a 100.0% win rate compared to 0.0%. Sett scales better into team fights and objective contests after 25 minutes.

Who wins the Zyra vs Sett matchup?

Sett wins the matchup against Zyra with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Sett is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Zyra build against Sett?

The best Zyra build against Sett includes Liandry's Torment, Zhonya's Hourglass, Rylai's Crystal Scepter with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Zyra runes against Sett?

The best Zyra runes against Sett use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Zyra vs Sett matchup. See the full rune breakdown in the matchup comparison above.

Does Zyra counter Sett?

No, Zyra struggles against Sett with only a 40.0% win rate. Sett has the advantage in this matchup. Zyra players should focus on safe farming and avoiding extended trades to minimize Sett's lead.

How do I play Zyra against Sett?

When playing Zyra against Sett, play cautiously and avoid Sett's power spikes. Look for jungle assistance and team-dependent plays since Sett has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.