Zyra - League of Legends Champion
Win Rate
51.2%
Pick Rate
2.0%

Zyravs Senna

AMageSupport
Patch26.14
Matches134,440
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 20, 2026
MethodologyData Methodology

Zyra vs Senna is a decisive matchup in LoL patch 26.14. Zyra wins with a 68.4% win rate (+36.8%) over Senna based on 19 games. Zyra holds the advantage in both the early and late game. Below you'll find the best Zyra build, runes, laning stats, and strategies for the Zyra vs Senna matchup.

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Zyra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zyra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zyra - 68.4% win rate in this matchup
Zyra
68.4% WR
VS
Senna vs Zyra matchup - 31.6% win rate
Senna
31.6% WR

Who Wins the Zyra vs Senna Matchup?

Zyra wins the Zyra vs Senna matchup
Winner
Zyra
Matches: 19
68.4%
Win Rate
31.6%
1.9
CS / min
2.0
844
DMG / min
542
9,092
Gold / game
9,191
119
Heal / min
379
300
DMG Mitigated / min
392
1.7
CC / min
1.1
55.6%
Early Game WR
44.4%
80.0%
Late Game WR
20.0%

Zyra vs Senna Matchup Summary

The Zyra vs Senna matchup is a decisive matchup in League of Legends ranked play. Based on 19 recent matches analyzed, Zyra wins with a 68.4% win rate compared to Senna's 31.6%, giving Zyra a 36.8 percentage point advantage. Zyra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Senna players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Senna leads by 352 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Zyra players can confidently pick into Senna and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Senna away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zyra vs Senna Laning Phase Breakdown

Senna wins the laning phase against Zyra in League of Legends

Senna is favored during the laning phase against Zyra, winning 3 out of 5 key stat categories. Senna holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
1.9Zyra
2.0Senna
Zyra and Senna farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
844Zyra
542Senna
Zyra heavily out-damages Senna by 302 DMG/min, dominating both short trades and all-in fights. Senna should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zyra's sustained damage advantage take over.
Economy
9,092Zyra
9,191Senna
Zyra and Senna generate nearly equal gold per game, with just a 99 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.7Zyra
1.1Senna
Zyra provides 0.6 seconds more crowd control per minute than Senna, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zyra coordinate with their jungler and control the pace of skirmishes.
Sustain
419Zyra
771Senna
Senna vastly out-sustains Zyra, healing and mitigating 352 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Zyra is forced to recall. Building grievous wounds early is essential for Zyra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zyra Build Against Senna

Sorcerer's Shoes is the optimal boots choice against Senna, providing the mobility and stats Zyra needs most in this matchup. The top-performing core items for Zyra against Senna are Liandry's Torment, Morellonomicon and Void Staff. This combination gives Zyra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Senna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zyra vs Senna matchup.

Early Game vs Late Game

Early Game
Zyra
55.6%
+11.1% advantage
Zyra early game win rateZyra55.6%
Senna early game win rateSenna44.4%
Late Game
Zyra
80.0%
+60.0% advantage
Zyra late game win rateZyra80.0%
Senna late game win rateSenna20.0%

Zyra dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 11.1 percentage point lead over Senna. This lopsided early game means Zyra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Zyra is far superior in the late game (25+ minutes), boasting a 80.0% win rate — 60.0 points above Senna. Extended games heavily favor Zyra, whose kit and scaling make them a dominant force in team fights and objective control.

Zyra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Senna players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Zyra Runes Against Senna

Sorcery rune tree - Zyra primary runes vs SennaSorcery
Arcane Comet - best Zyra rune vs SennaManaflow Band - best Zyra rune vs SennaTranscendence - best Zyra rune vs SennaScorch - best Zyra rune vs Senna
Domination rune tree - Zyra secondary runes vs SennaDomination
Relentless Hunter - best Zyra rune vs SennaTaste of Blood - best Zyra rune vs Senna
80.0% WR

Running Sorcery primary with Domination secondary allows Zyra to press their advantage against Senna, amplifying the strengths that make this a favorable matchup.


Zyra matchup data for League of Legends patch 26.14. The table below shows Zyra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zyra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zyra matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.67%452.16909,05538.1%54.2%
46.67%302.16898,04050.0%41.7%
62.07%291.979610,21960.0%64.3%
60.87%231.97119,52640.0%76.9%
47.62%212.182710,17766.7%40.0%
45.00%201.96908,46562.5%33.3%
68.42%191.98449,09255.6%80.0%
40.00%151.97116,87542.9%37.5%
38.46%131.67039,02966.7%30.0%
45.45%111.66699,27150.0%42.9%
45.45%111.964410,75650.0%42.9%
45.45%111.871410,630100.0%40.0%
70.00%101.87718,99850.0%83.3%
80.00%101.67139,37466.7%85.7%
50.00%102.174510,24933.3%57.1%
33.33%92.284412,1820.0%37.5%
22.22%92.181310,65450.0%0.0%
55.56%92.27408,35050.0%60.0%
44.44%92.06979,25225.0%60.0%
37.50%82.17329,28333.3%40.0%
75.00%82.37198,59966.7%80.0%
37.50%81.66706,79325.0%50.0%
37.50%82.07507,92075.0%0.0%
25.00%85.37208,70540.0%0.0%
37.50%82.291210,63466.7%20.0%
28.57%71.65787,39625.0%33.3%
57.14%72.17638,67533.3%75.0%
42.86%72.85439,48033.3%50.0%
50.00%62.18069,50650.0%50.0%
50.00%62.475012,4390.0%50.0%
83.33%61.87298,314100.0%66.7%
66.67%61.583710,80450.0%75.0%

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Zyra vs Senna - Frequently Asked Questions

How does Zyra do against Senna in League of Legends?

Zyra wins the Zyra vs Senna matchup with a 68.4% win rate compared to Senna's 31.6%, a 36.8 percentage point difference. This data is based on 19 recent ranked games in patch 26.14.

How does Zyra do against Senna in the early game?

In the early game, Zyra has the advantage against Senna with a 55.6% win rate versus 44.4%. Zyra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zyra do against Senna in the late game?

In the late game, Zyra takes over the Zyra vs Senna matchup with a 80.0% win rate compared to 20.0%. Zyra scales better into team fights and objective contests after 25 minutes.

Who wins the Zyra vs Senna matchup?

Zyra wins the matchup against Senna with a 68.4% win rate in League of Legends patch 26.14. The 36.8 percentage point advantage means Zyra is significantly favored in this lane matchup based on 19 games analyzed.

What is the best Zyra build against Senna?

The best Zyra build against Senna includes Liandry's Torment, Morellonomicon, Void Staff with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zyra runes against Senna?

The best Zyra runes against Senna use the Sorcery primary tree with Domination secondary. This rune setup achieves a 80.0% win rate in the Zyra vs Senna matchup. See the full rune breakdown in the matchup comparison above.

Does Zyra counter Senna?

Yes, Zyra has a favorable matchup against Senna with a 68.4% win rate. Zyra strongly counters Senna in lane based on current patch 26.14 data.

How do I play Zyra against Senna?

When playing Zyra against Senna, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.