Zyra - League of Legends Champion
Win Rate
51.5%
Pick Rate
2.8%

Zyravs Senna

SMageSupport
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Zyra vs Senna is a decisive matchup in LoL patch 26.7. Senna wins with a 56.5% win rate (+12.9%) over Zyra based on 62 games. Senna holds the advantage in both the early and late game. Below you'll find the best Zyra build, runes, laning stats, and strategies for the Zyra vs Senna matchup.

Zyra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zyra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Senna - 43.5% win rateSenna(43.5%)
Zyra - 43.5% win rate in this matchup
Zyra
43.5% WR
VS
Senna vs Zyra matchup - 56.5% win rate
Senna
56.5% WR

Who Wins the Zyra vs Senna Matchup?

Senna wins the Zyra vs Senna matchup
Winner
Senna
Matches: 62
43.5%
Win Rate
56.5%
1.8
CS / min
1.7
762
DMG / min
559
9,748
Gold / game
10,868
80
Heal / min
522
301
DMG Mitigated / min
356
1.7
CC / min
1.1
36.4%
Early Game WR
63.6%
47.5%
Late Game WR
52.5%

Zyra vs Senna Matchup Summary

The Zyra vs Senna matchup is a decisive matchup in League of Legends ranked play. Based on 62 recent matches analyzed, Senna wins with a 56.5% win rate compared to Zyra's 43.5%, giving Senna a 12.9 percentage point advantage. Senna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Zyra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Senna leads by 496 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Senna has a strong advantage in this matchup. Zyra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Senna overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zyra vs Senna Laning Phase Breakdown

Zyra wins the laning phase against Senna in League of Legends

Zyra is favored during the laning phase against Senna, winning 3 out of 5 key stat categories. Zyra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
1.8Zyra
1.7Senna
Zyra and Senna farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
762Zyra
559Senna
Zyra heavily out-damages Senna by 203 DMG/min, dominating both short trades and all-in fights. Senna should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zyra's sustained damage advantage take over.
Economy
9,748Zyra
10,868Senna
Senna generates a commanding 1,120 more gold per game than Zyra. This substantial economic advantage means Senna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Zyra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.7Zyra
1.1Senna
Zyra provides 0.6 seconds more crowd control per minute than Senna, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zyra coordinate with their jungler and control the pace of skirmishes.
Sustain
381Zyra
877Senna
Senna vastly out-sustains Zyra, healing and mitigating 496 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Zyra is forced to recall. Building grievous wounds early is essential for Zyra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zyra Build Against Senna

Sorcerer's Shoes is the optimal boots choice against Senna, providing the mobility and stats Zyra needs most in this matchup. The top-performing core items for Zyra against Senna are Liandry's Torment, Morellonomicon and Rylai's Crystal Scepter. This combination gives Zyra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Senna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zyra vs Senna matchup.

Early Game vs Late Game

Early Game
Senna
63.6%
+27.3% advantage
Zyra early game win rateZyra36.4%
Senna early game win rateSenna63.6%
Late Game
Senna
52.5%
+5.0% advantage
Zyra late game win rateZyra47.5%
Senna late game win rateSenna52.5%

Senna dominates the early game (first 15 minutes) with a commanding 63.6% win rate — a 27.3 percentage point lead over Zyra. This lopsided early game means Senna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Senna is far superior in the late game (25+ minutes), boasting a 52.5% win rate — 5.0 points above Zyra. Extended games heavily favor Senna, whose kit and scaling make them a dominant force in team fights and objective control.

Senna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Zyra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Zyra Runes Against Senna

Sorcery rune tree - Zyra primary runes vs SennaSorcery
Arcane Comet - best Zyra rune vs SennaManaflow Band - best Zyra rune vs SennaTranscendence - best Zyra rune vs SennaScorch - best Zyra rune vs Senna
Domination rune tree - Zyra secondary runes vs SennaDomination
Relentless Hunter - best Zyra rune vs SennaTaste of Blood - best Zyra rune vs Senna
36.4% WR

The Sorcery and Domination rune setup gives Zyra the best tools to compete against Senna in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Zyra matchup data for League of Legends patch 26.7. The table below shows Zyra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zyra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zyra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
53.03%1321.77389,44957.6%49.3%
57.14%1261.973710,56664.9%53.9%
47.93%1211.87469,67255.1%43.1%
52.43%1031.974710,16363.4%45.2%
55.32%941.976110,11345.7%61.0%
57.78%901.873410,33561.1%55.6%
43.21%811.77529,44950.0%37.2%
48.75%801.878210,02744.1%52.2%
57.75%711.880410,55950.0%62.2%
64.18%672.079511,28661.9%65.2%
43.75%641.97019,66340.0%46.1%
59.68%621.87319,22170.4%51.4%
43.55%621.87629,74836.4%47.5%
39.34%611.86669,11726.7%51.6%
53.33%602.186010,22153.9%52.9%
48.28%582.47049,79962.5%38.2%
50.88%571.87549,99642.9%58.6%
48.08%521.97859,84158.3%39.3%
52.00%502.05969,91752.2%51.9%
46.94%492.677110,65958.8%40.6%
45.83%481.96729,45145.0%46.4%
55.81%431.67849,80366.7%45.5%
35.00%401.77249,65718.8%45.8%
55.26%381.990610,81742.9%62.5%
38.89%362.082811,31658.3%29.2%
48.57%351.68149,48861.5%40.9%
55.88%341.88099,77264.3%50.0%
42.42%331.879712,54023.1%55.0%
43.33%301.274912,27954.5%36.8%
50.00%301.87719,62937.5%64.3%
60.71%282.387210,44060.0%61.1%
28.00%251.77498,94315.4%41.7%
64.00%251.878610,64085.7%55.6%
60.00%251.485113,18655.6%62.5%
58.33%241.97499,09956.3%62.5%
40.91%221.585912,89911.1%61.5%
54.55%222.680311,81383.3%43.8%
50.00%201.381611,74853.9%42.9%
40.00%202.165910,09737.5%41.7%
40.00%201.676611,94736.4%44.4%
63.16%191.879011,21677.8%50.0%
63.16%191.678712,66728.6%83.3%
47.37%192.58209,99844.4%50.0%
55.56%181.686510,88987.5%30.0%
61.11%182.785211,77180.0%53.9%
38.89%181.382112,73833.3%50.0%
52.94%171.577813,34675.0%33.3%
50.00%162.38459,69160.0%45.5%
75.00%161.082411,66190.0%50.0%
60.00%151.487213,764100.0%45.5%
46.67%152.71,12213,61375.0%36.4%
53.33%152.284610,87733.3%83.3%
66.67%152.479210,91050.0%77.8%
85.71%141.31,02312,88375.0%100.0%
57.14%141.395413,46860.0%55.6%
84.62%131.693613,68383.3%85.7%
46.15%134.680611,35160.0%37.5%
38.46%132.51,06513,91025.0%44.4%
41.67%126.38118,96050.0%33.3%
50.00%121.998511,40042.9%60.0%
16.67%123.583711,97820.0%14.3%
66.67%121.71,01512,92133.3%77.8%
72.73%115.998713,86950.0%85.7%
63.64%112.999510,87950.0%71.4%
54.55%115.97709,27850.0%60.0%
50.00%105.896512,23950.0%50.0%
50.00%101.473510,84066.7%25.0%
60.00%103.36267,78233.3%100.0%
50.00%101.292612,73333.3%57.1%
44.44%91.38719,74333.3%66.7%
55.56%91.392012,10750.0%57.1%
44.44%92.777611,02650.0%42.9%
25.00%85.599112,38850.0%16.7%
50.00%85.587410,51633.3%60.0%
62.50%85.57429,33875.0%50.0%
25.00%85.685610,82825.0%25.0%
75.00%81.584915,037100.0%71.4%
62.50%81.489514,02050.0%66.7%
25.00%81.791314,67250.0%16.7%
62.50%81.71,02515,9400.0%71.4%
75.00%86.797711,582100.0%33.3%
57.14%71.61,01414,3470.0%66.7%
71.43%75.879011,29750.0%80.0%
57.14%71.97939,60466.7%50.0%
71.43%72.181713,08850.0%100.0%
57.14%70.972112,17366.7%50.0%
57.14%73.372710,40150.0%66.7%
57.14%73.578112,070100.0%40.0%
71.43%71.21,08612,924100.0%60.0%
71.43%73.09569,873100.0%60.0%
57.14%71.884714,16450.0%60.0%
42.86%73.579910,4820.0%60.0%
57.14%71.887812,15550.0%60.0%
28.57%73.674510,13066.7%0.0%
14.29%75.087211,33150.0%0.0%
57.14%71.474512,29433.3%75.0%
42.86%71.77618,45250.0%33.3%
83.33%64.11,09415,5240.0%83.3%
50.00%61.11,02314,197100.0%25.0%
50.00%61.590914,5550.0%50.0%
33.33%61.81,01512,33533.3%33.3%
50.00%65.171710,3930.0%75.0%
50.00%61.071310,48666.7%33.3%
33.33%65.97768,08425.0%50.0%
33.33%62.41,12612,69850.0%25.0%
80.00%55.578310,43950.0%100.0%
20.00%53.184713,3640.0%25.0%
80.00%51.581411,641100.0%66.7%
20.00%52.35989,1770.0%33.3%
60.00%54.77619,06833.3%100.0%
20.00%55.583110,3030.0%33.3%

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Zyra vs Senna - Frequently Asked Questions

How does Zyra do against Senna in League of Legends?

Senna wins the Zyra vs Senna matchup with a 56.5% win rate compared to Zyra's 43.5%, a 12.9 percentage point difference. This data is based on 62 recent ranked games in patch 26.7.

How does Zyra do against Senna in the early game?

In the early game, Senna has the advantage against Zyra with a 63.6% win rate versus 36.4%. Senna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zyra do against Senna in the late game?

In the late game, Senna takes over the Zyra vs Senna matchup with a 52.5% win rate compared to 47.5%. Senna scales better into team fights and objective contests after 25 minutes.

Who wins the Zyra vs Senna matchup?

Senna wins the matchup against Zyra with a 56.5% win rate in League of Legends patch 26.7. The 12.9 percentage point advantage means Senna is significantly favored in this lane matchup based on 62 games analyzed.

What is the best Zyra build against Senna?

The best Zyra build against Senna includes Liandry's Torment, Morellonomicon, Rylai's Crystal Scepter with Sorcerer's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zyra runes against Senna?

The best Zyra runes against Senna use the Sorcery primary tree with Domination secondary. This rune setup achieves a 36.4% win rate in the Zyra vs Senna matchup. See the full rune breakdown in the matchup comparison above.

Does Zyra counter Senna?

No, Zyra struggles against Senna with only a 43.5% win rate. Senna has the advantage in this matchup. Zyra players should focus on safe farming and avoiding extended trades to minimize Senna's lead.

How do I play Zyra against Senna?

When playing Zyra against Senna, play cautiously and avoid Senna's power spikes. Look for jungle assistance and team-dependent plays since Senna has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.