Zyra - League of Legends Champion
Win Rate
47.0%
Pick Rate
2.5%

Zyravs Seraphine

FMageSupport
Patch26.12
Matches112,472
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 15, 2026
MethodologyData Methodology

Zyra vs Seraphine is a decisive matchup in LoL patch 26.12. Seraphine wins with a 70.3% win rate (+40.5%) over Zyra based on 37 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Zyra build, runes, laning stats, and strategies for the Zyra vs Seraphine matchup.

Metabot Logo
MetaBot Desktop
Live In-Game Overlays
Join Our Discord
Bug reports, feature requests & developer chat
Join Discord

Zyra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zyra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zyra - 29.7% win rate in this matchup
Zyra
29.7% WR
VS
Seraphine vs Zyra matchup - 70.3% win rate
Seraphine
70.3% WR

Who Wins the Zyra vs Seraphine Matchup?

Seraphine wins the Zyra vs Seraphine matchup
Winner
Seraphine
Matches: 37
29.7%
Win Rate
70.3%
1.9
CS / min
1.5
748
DMG / min
469
9,141
Gold / game
9,356
81
Heal / min
318
326
DMG Mitigated / min
389
1.6
CC / min
1.1
30.8%
Early Game WR
69.2%
29.2%
Late Game WR
70.8%

Zyra vs Seraphine Matchup Summary

The Zyra vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 37 recent matches analyzed, Seraphine wins with a 70.3% win rate compared to Zyra's 29.7%, giving Seraphine a 40.5 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Zyra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Seraphine leads by 299 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Zyra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zyra vs Seraphine Laning Phase Breakdown

Zyra wins the laning phase against Seraphine in League of Legends

Zyra is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Zyra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
1.9Zyra
1.5Seraphine
Zyra edges out Seraphine by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Zyra.
Damage
748Zyra
469Seraphine
Zyra heavily out-damages Seraphine by 279 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zyra's sustained damage advantage take over.
Economy
9,141Zyra
9,356Seraphine
Zyra and Seraphine generate nearly equal gold per game, with just a 215 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.6Zyra
1.1Seraphine
Zyra provides 0.6 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zyra coordinate with their jungler and control the pace of skirmishes.
Sustain
407Zyra
706Seraphine
Seraphine vastly out-sustains Zyra, healing and mitigating 299 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Zyra is forced to recall. Building grievous wounds early is essential for Zyra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zyra Build Against Seraphine

Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Zyra needs most in this matchup. The top-performing core items for Zyra against Seraphine are Liandry's Torment, Morellonomicon and Rylai's Crystal Scepter. This combination gives Zyra an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Zyra the best chance to compete against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zyra vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
69.2%
+38.5% advantage
Zyra early game win rateZyra30.8%
Seraphine early game win rateSeraphine69.2%
Late Game
Seraphine
70.8%
+41.7% advantage
Zyra late game win rateZyra29.2%
Seraphine late game win rateSeraphine70.8%

Seraphine dominates the early game (first 15 minutes) with a commanding 69.2% win rate — a 38.5 percentage point lead over Zyra. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 70.8% win rate — 41.7 points above Zyra. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Zyra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Zyra Runes Against Seraphine

Sorcery rune tree - Zyra primary runes vs SeraphineSorcery
Arcane Comet - best Zyra rune vs SeraphineManaflow Band - best Zyra rune vs SeraphineTranscendence - best Zyra rune vs SeraphineScorch - best Zyra rune vs Seraphine
Domination rune tree - Zyra secondary runes vs SeraphineDomination
Taste of Blood - best Zyra rune vs SeraphineRelentless Hunter - best Zyra rune vs Seraphine
40.0% WR

The Sorcery and Domination rune setup gives Zyra the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Zyra matchup data for League of Legends patch 26.12. The table below shows Zyra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zyra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zyra matchup win rates and stats in League of Legends patch 26.12
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
29.73%371.97489,14130.8%29.2%
35.48%312.378810,70330.0%38.1%
37.50%243.488510,74436.4%38.5%
54.17%242.07139,97966.7%46.7%
30.43%231.872910,9690.0%36.8%
47.37%191.582210,71766.7%43.8%
38.89%182.880910,78714.3%54.5%
55.56%181.67008,65255.6%55.6%
50.00%162.08598,21055.6%42.9%
57.14%141.991410,63066.7%50.0%
30.77%132.28509,92633.3%28.6%
38.46%132.067710,05933.3%42.9%
54.55%111.769810,37966.7%50.0%
63.64%112.16629,82950.0%71.4%
40.00%101.77449,48425.0%50.0%
80.00%102.176411,508100.0%75.0%
44.44%92.087412,399100.0%37.5%
22.22%91.87479,06220.0%25.0%
66.67%91.78559,29780.0%50.0%
66.67%92.487411,60450.0%71.4%
50.00%81.68369,15960.0%33.3%
25.00%81.86578,98640.0%0.0%
25.00%82.28259,7030.0%40.0%
62.50%82.076214,4710.0%62.5%
50.00%82.07698,04950.0%50.0%
71.43%71.67199,45875.0%66.7%
57.14%72.073811,50866.7%50.0%
33.33%61.183711,16033.3%33.3%
16.67%61.87158,6090.0%25.0%
66.67%61.61,04310,26166.7%66.7%
50.00%61.169010,07566.7%33.3%
80.00%51.97379,31150.0%100.0%
60.00%51.381113,5830.0%100.0%
40.00%51.575411,5650.0%40.0%
80.00%55.086912,803100.0%75.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Zyra vs Seraphine - Frequently Asked Questions

How does Zyra do against Seraphine in League of Legends?

Seraphine wins the Zyra vs Seraphine matchup with a 70.3% win rate compared to Zyra's 29.7%, a 40.5 percentage point difference. This data is based on 37 recent ranked games in patch 26.12.

How does Zyra do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Zyra with a 69.2% win rate versus 30.8%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zyra do against Seraphine in the late game?

In the late game, Seraphine takes over the Zyra vs Seraphine matchup with a 70.8% win rate compared to 29.2%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Zyra vs Seraphine matchup?

Seraphine wins the matchup against Zyra with a 70.3% win rate in League of Legends patch 26.12. The 40.5 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 37 games analyzed.

What is the best Zyra build against Seraphine?

The best Zyra build against Seraphine includes Liandry's Torment, Morellonomicon, Rylai's Crystal Scepter with Sorcerer's Shoes. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zyra runes against Seraphine?

The best Zyra runes against Seraphine use the Sorcery primary tree with Domination secondary. This rune setup achieves a 40.0% win rate in the Zyra vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Zyra counter Seraphine?

No, Zyra struggles against Seraphine with only a 29.7% win rate. Seraphine has the advantage in this matchup. Zyra players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Zyra against Seraphine?

When playing Zyra against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.