Zyra - League of Legends Champion
Win Rate
51.5%
Pick Rate
2.8%

Zyravs Seraphine

SMageSupport
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 21, 2026
MethodologyData Methodology

Zyra vs Seraphine is a moderate matchup in LoL patch 26.7. Zyra wins with a 52.4% win rate (+4.9%) over Seraphine based on 103 games. Zyra wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Zyra build, runes, laning stats, and strategies for the Zyra vs Seraphine matchup.

Zyra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Zyra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 52.4% win rateSeraphine(52.4%)
Zyra - 52.4% win rate in this matchup
Zyra
52.4% WR
VS
Seraphine vs Zyra matchup - 47.6% win rate
Seraphine
47.6% WR

Who Wins the Zyra vs Seraphine Matchup?

Zyra wins the Zyra vs Seraphine matchup
Winner
Zyra
Matches: 103
52.4%
Win Rate
47.6%
1.9
CS / min
1.5
747
DMG / min
444
10,163
Gold / game
9,601
102
Heal / min
327
292
DMG Mitigated / min
373
1.7
CC / min
1.1
63.4%
Early Game WR
36.6%
45.2%
Late Game WR
54.8%

Zyra vs Seraphine Matchup Summary

The Zyra vs Seraphine matchup is a moderate matchup in League of Legends ranked play. Based on 103 recent matches analyzed, Zyra wins with a 52.4% win rate compared to Seraphine's 47.6%, giving Zyra a 4.9 percentage point advantage. Game phase dynamics play a critical role here: Zyra controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Zyra needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Seraphine leads by 306 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Zyra has a statistical edge, but the margin is close enough that respecting Seraphine's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Zyra vs Seraphine Laning Phase Breakdown

Zyra wins the laning phase against Seraphine in League of Legends

Zyra is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Zyra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.9Zyra
1.5Seraphine
Zyra edges out Seraphine by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Zyra.
Damage
747Zyra
444Seraphine
Zyra heavily out-damages Seraphine by 303 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zyra's sustained damage advantage take over.
Economy
10,163Zyra
9,601Seraphine
Zyra earns 562 more gold per game than Seraphine, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Zyra slightly faster item completions.
Utility
1.7Zyra
1.1Seraphine
Zyra provides 0.6 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zyra coordinate with their jungler and control the pace of skirmishes.
Sustain
394Zyra
700Seraphine
Seraphine vastly out-sustains Zyra, healing and mitigating 306 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Zyra is forced to recall. Building grievous wounds early is essential for Zyra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Zyra Build Against Seraphine

Ionian Boots of Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Zyra needs most in this matchup. The top-performing core items for Zyra against Seraphine are Liandry's Torment, Malignance and Rylai's Crystal Scepter. This combination gives Zyra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 75.0% win rate across 4 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zyra vs Seraphine matchup.

Early Game vs Late Game

Early Game
Zyra
63.4%
+26.8% advantage
Zyra early game win rateZyra63.4%
Seraphine early game win rateSeraphine36.6%
Late Game
Seraphine
54.8%
+9.7% advantage
Zyra late game win rateZyra45.2%
Seraphine late game win rateSeraphine54.8%

Zyra dominates the early game (first 15 minutes) with a commanding 63.4% win rate — a 26.8 percentage point lead over Seraphine. This lopsided early game means Zyra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 54.8% win rate — 9.7 points above Zyra. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Zyra must aggressively press their early advantage and close out the game before Seraphine reaches their scaling breakpoints. If Seraphine survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Zyra Runes Against Seraphine

Sorcery rune tree - Zyra primary runes vs SeraphineSorcery
Arcane Comet - best Zyra rune vs SeraphineManaflow Band - best Zyra rune vs SeraphineTranscendence - best Zyra rune vs SeraphineScorch - best Zyra rune vs Seraphine
Domination rune tree - Zyra secondary runes vs SeraphineDomination
Relentless Hunter - best Zyra rune vs SeraphineTaste of Blood - best Zyra rune vs Seraphine
66.7% WR

Running Sorcery primary with Domination secondary allows Zyra to press their advantage against Seraphine, amplifying the strengths that make this a favorable matchup.


Zyra matchup data for League of Legends patch 26.7. The table below shows Zyra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zyra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Zyra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
53.03%1321.77389,44957.6%49.3%
57.14%1261.973710,56664.9%53.9%
47.93%1211.87469,67255.1%43.1%
52.43%1031.974710,16363.4%45.2%
55.32%941.976110,11345.7%61.0%
57.78%901.873410,33561.1%55.6%
43.21%811.77529,44950.0%37.2%
48.75%801.878210,02744.1%52.2%
57.75%711.880410,55950.0%62.2%
64.18%672.079511,28661.9%65.2%
43.75%641.97019,66340.0%46.1%
59.68%621.87319,22170.4%51.4%
43.55%621.87629,74836.4%47.5%
39.34%611.86669,11726.7%51.6%
53.33%602.186010,22153.9%52.9%
48.28%582.47049,79962.5%38.2%
50.88%571.87549,99642.9%58.6%
48.08%521.97859,84158.3%39.3%
52.00%502.05969,91752.2%51.9%
46.94%492.677110,65958.8%40.6%
45.83%481.96729,45145.0%46.4%
55.81%431.67849,80366.7%45.5%
35.00%401.77249,65718.8%45.8%
55.26%381.990610,81742.9%62.5%
38.89%362.082811,31658.3%29.2%
48.57%351.68149,48861.5%40.9%
55.88%341.88099,77264.3%50.0%
42.42%331.879712,54023.1%55.0%
43.33%301.274912,27954.5%36.8%
50.00%301.87719,62937.5%64.3%
60.71%282.387210,44060.0%61.1%
28.00%251.77498,94315.4%41.7%
64.00%251.878610,64085.7%55.6%
60.00%251.485113,18655.6%62.5%
58.33%241.97499,09956.3%62.5%
40.91%221.585912,89911.1%61.5%
54.55%222.680311,81383.3%43.8%
50.00%201.381611,74853.9%42.9%
40.00%202.165910,09737.5%41.7%
40.00%201.676611,94736.4%44.4%
63.16%191.879011,21677.8%50.0%
63.16%191.678712,66728.6%83.3%
47.37%192.58209,99844.4%50.0%
55.56%181.686510,88987.5%30.0%
61.11%182.785211,77180.0%53.9%
38.89%181.382112,73833.3%50.0%
52.94%171.577813,34675.0%33.3%
50.00%162.38459,69160.0%45.5%
75.00%161.082411,66190.0%50.0%
60.00%151.487213,764100.0%45.5%
46.67%152.71,12213,61375.0%36.4%
53.33%152.284610,87733.3%83.3%
66.67%152.479210,91050.0%77.8%
85.71%141.31,02312,88375.0%100.0%
57.14%141.395413,46860.0%55.6%
84.62%131.693613,68383.3%85.7%
46.15%134.680611,35160.0%37.5%
38.46%132.51,06513,91025.0%44.4%
41.67%126.38118,96050.0%33.3%
50.00%121.998511,40042.9%60.0%
16.67%123.583711,97820.0%14.3%
66.67%121.71,01512,92133.3%77.8%
72.73%115.998713,86950.0%85.7%
63.64%112.999510,87950.0%71.4%
54.55%115.97709,27850.0%60.0%
50.00%105.896512,23950.0%50.0%
50.00%101.473510,84066.7%25.0%
60.00%103.36267,78233.3%100.0%
50.00%101.292612,73333.3%57.1%
44.44%91.38719,74333.3%66.7%
55.56%91.392012,10750.0%57.1%
44.44%92.777611,02650.0%42.9%
25.00%85.599112,38850.0%16.7%
50.00%85.587410,51633.3%60.0%
62.50%85.57429,33875.0%50.0%
25.00%85.685610,82825.0%25.0%
75.00%81.584915,037100.0%71.4%
62.50%81.489514,02050.0%66.7%
25.00%81.791314,67250.0%16.7%
62.50%81.71,02515,9400.0%71.4%
75.00%86.797711,582100.0%33.3%
57.14%71.61,01414,3470.0%66.7%
71.43%75.879011,29750.0%80.0%
57.14%71.97939,60466.7%50.0%
71.43%72.181713,08850.0%100.0%
57.14%70.972112,17366.7%50.0%
57.14%73.372710,40150.0%66.7%
57.14%73.578112,070100.0%40.0%
71.43%71.21,08612,924100.0%60.0%
71.43%73.09569,873100.0%60.0%
57.14%71.884714,16450.0%60.0%
42.86%73.579910,4820.0%60.0%
57.14%71.887812,15550.0%60.0%
28.57%73.674510,13066.7%0.0%
14.29%75.087211,33150.0%0.0%
57.14%71.474512,29433.3%75.0%
42.86%71.77618,45250.0%33.3%
83.33%64.11,09415,5240.0%83.3%
50.00%61.11,02314,197100.0%25.0%
50.00%61.590914,5550.0%50.0%
33.33%61.81,01512,33533.3%33.3%
50.00%65.171710,3930.0%75.0%
50.00%61.071310,48666.7%33.3%
33.33%65.97768,08425.0%50.0%
33.33%62.41,12612,69850.0%25.0%
80.00%55.578310,43950.0%100.0%
20.00%53.184713,3640.0%25.0%
80.00%51.581411,641100.0%66.7%
20.00%52.35989,1770.0%33.3%
60.00%54.77619,06833.3%100.0%
20.00%55.583110,3030.0%33.3%

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Zyra vs Seraphine - Frequently Asked Questions

How does Zyra do against Seraphine in League of Legends?

Zyra wins the Zyra vs Seraphine matchup with a 52.4% win rate compared to Seraphine's 47.6%, a 4.9 percentage point difference. This data is based on 103 recent ranked games in patch 26.7.

How does Zyra do against Seraphine in the early game?

In the early game, Zyra has the advantage against Seraphine with a 63.4% win rate versus 36.6%. Zyra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Zyra do against Seraphine in the late game?

In the late game, Seraphine takes over the Zyra vs Seraphine matchup with a 54.8% win rate compared to 45.2%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Zyra vs Seraphine matchup?

Zyra wins the matchup against Seraphine with a 52.4% win rate in League of Legends patch 26.7. The 4.9 percentage point advantage means Zyra is moderately favored in this lane matchup based on 103 games analyzed.

What is the best Zyra build against Seraphine?

The best Zyra build against Seraphine includes Liandry's Torment, Malignance, Rylai's Crystal Scepter with Ionian Boots of Lucidity. This build achieves a 75.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Zyra runes against Seraphine?

The best Zyra runes against Seraphine use the Sorcery primary tree with Domination secondary. This rune setup achieves a 66.7% win rate in the Zyra vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Zyra counter Seraphine?

Yes, Zyra has a favorable matchup against Seraphine with a 52.4% win rate. Zyra has a solid advantage over Seraphine in lane based on current patch 26.7 data.

How do I play Zyra against Seraphine?

When playing Zyra against Seraphine, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.