
Zyravs Seraphine
Zyra vs Seraphine is a decisive matchup in LoL patch 26.12. Seraphine wins with a 70.3% win rate (+40.5%) over Zyra based on 37 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Zyra build, runes, laning stats, and strategies for the Zyra vs Seraphine matchup.
Zyra Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zyra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Zyra vs Seraphine Matchup?

Zyra vs Seraphine Matchup Summary
The Zyra vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 37 recent matches analyzed, Seraphine wins with a 70.3% win rate compared to Zyra's 29.7%, giving Seraphine a 40.5 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Zyra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Seraphine leads by 299 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Zyra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Zyra vs Seraphine Laning Phase Breakdown
Zyra is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Zyra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.
Best Zyra Build Against Seraphine
Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Zyra needs most in this matchup. The top-performing core items for Zyra against Seraphine are Liandry's Torment, Morellonomicon and Rylai's Crystal Scepter. This combination gives Zyra an effective balance of damage, survivability, and utility for the matchup. This build has a 33.3% win rate across 3 games. While the overall matchup may be difficult, this item path gives Zyra the best chance to compete against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zyra vs Seraphine matchup.
Early Game vs Late Game
Seraphine dominates the early game (first 15 minutes) with a commanding 69.2% win rate — a 38.5 percentage point lead over Zyra. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Seraphine is far superior in the late game (25+ minutes), boasting a 70.8% win rate — 41.7 points above Zyra. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.
Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Zyra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Zyra Runes Against Seraphine
The Sorcery and Domination rune setup gives Zyra the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Zyra matchup data for League of Legends patch 26.12. The table below shows Zyra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zyra build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 29.73% | 37 | 1.9 | 748 | 9,141 | 30.8% | 29.2% | |
| 35.48% | 31 | 2.3 | 788 | 10,703 | 30.0% | 38.1% | |
| 37.50% | 24 | 3.4 | 885 | 10,744 | 36.4% | 38.5% | |
| 54.17% | 24 | 2.0 | 713 | 9,979 | 66.7% | 46.7% | |
| 30.43% | 23 | 1.8 | 729 | 10,969 | 0.0% | 36.8% | |
| 47.37% | 19 | 1.5 | 822 | 10,717 | 66.7% | 43.8% | |
| 38.89% | 18 | 2.8 | 809 | 10,787 | 14.3% | 54.5% | |
| 55.56% | 18 | 1.6 | 700 | 8,652 | 55.6% | 55.6% | |
| 50.00% | 16 | 2.0 | 859 | 8,210 | 55.6% | 42.9% | |
| 57.14% | 14 | 1.9 | 914 | 10,630 | 66.7% | 50.0% | |
| 30.77% | 13 | 2.2 | 850 | 9,926 | 33.3% | 28.6% | |
| 38.46% | 13 | 2.0 | 677 | 10,059 | 33.3% | 42.9% | |
| 54.55% | 11 | 1.7 | 698 | 10,379 | 66.7% | 50.0% | |
| 63.64% | 11 | 2.1 | 662 | 9,829 | 50.0% | 71.4% | |
| 40.00% | 10 | 1.7 | 744 | 9,484 | 25.0% | 50.0% | |
| 80.00% | 10 | 2.1 | 764 | 11,508 | 100.0% | 75.0% | |
| 44.44% | 9 | 2.0 | 874 | 12,399 | 100.0% | 37.5% | |
| 22.22% | 9 | 1.8 | 747 | 9,062 | 20.0% | 25.0% | |
| 66.67% | 9 | 1.7 | 855 | 9,297 | 80.0% | 50.0% | |
| 66.67% | 9 | 2.4 | 874 | 11,604 | 50.0% | 71.4% | |
| 50.00% | 8 | 1.6 | 836 | 9,159 | 60.0% | 33.3% | |
| 25.00% | 8 | 1.8 | 657 | 8,986 | 40.0% | 0.0% | |
| 25.00% | 8 | 2.2 | 825 | 9,703 | 0.0% | 40.0% | |
| 62.50% | 8 | 2.0 | 762 | 14,471 | 0.0% | 62.5% | |
| 50.00% | 8 | 2.0 | 769 | 8,049 | 50.0% | 50.0% | |
| 71.43% | 7 | 1.6 | 719 | 9,458 | 75.0% | 66.7% | |
| 57.14% | 7 | 2.0 | 738 | 11,508 | 66.7% | 50.0% | |
| 33.33% | 6 | 1.1 | 837 | 11,160 | 33.3% | 33.3% | |
| 16.67% | 6 | 1.8 | 715 | 8,609 | 0.0% | 25.0% | |
| 66.67% | 6 | 1.6 | 1,043 | 10,261 | 66.7% | 66.7% | |
| 50.00% | 6 | 1.1 | 690 | 10,075 | 66.7% | 33.3% | |
| 80.00% | 5 | 1.9 | 737 | 9,311 | 50.0% | 100.0% | |
| 60.00% | 5 | 1.3 | 811 | 13,583 | 0.0% | 100.0% | |
| 40.00% | 5 | 1.5 | 754 | 11,565 | 0.0% | 40.0% | |
| 80.00% | 5 | 5.0 | 869 | 12,803 | 100.0% | 75.0% |
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Zyra vs Seraphine - Frequently Asked Questions
How does Zyra do against Seraphine in League of Legends?
Seraphine wins the Zyra vs Seraphine matchup with a 70.3% win rate compared to Zyra's 29.7%, a 40.5 percentage point difference. This data is based on 37 recent ranked games in patch 26.12.
How does Zyra do against Seraphine in the early game?
In the early game, Seraphine has the advantage against Zyra with a 69.2% win rate versus 30.8%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Zyra do against Seraphine in the late game?
In the late game, Seraphine takes over the Zyra vs Seraphine matchup with a 70.8% win rate compared to 29.2%. Seraphine scales better into team fights and objective contests after 25 minutes.
Who wins the Zyra vs Seraphine matchup?
Seraphine wins the matchup against Zyra with a 70.3% win rate in League of Legends patch 26.12. The 40.5 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 37 games analyzed.
What is the best Zyra build against Seraphine?
The best Zyra build against Seraphine includes Liandry's Torment, Morellonomicon, Rylai's Crystal Scepter with Sorcerer's Shoes. This build achieves a 33.3% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Zyra runes against Seraphine?
The best Zyra runes against Seraphine use the Sorcery primary tree with Domination secondary. This rune setup achieves a 40.0% win rate in the Zyra vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.
Does Zyra counter Seraphine?
No, Zyra struggles against Seraphine with only a 29.7% win rate. Seraphine has the advantage in this matchup. Zyra players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.
How do I play Zyra against Seraphine?
When playing Zyra against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.
