
Zyravs Seraphine
Zyra vs Seraphine is a decisive matchup in LoL patch 26.19. Seraphine wins with a 54.7% win rate (+9.4%) over Zyra based on 139 games. Seraphine wins the early laning phase while Zyra scales better into the late game. Below you'll find the best Zyra build, runes, laning stats, and strategies for the Zyra vs Seraphine matchup.
Zyra Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zyra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.


Who wins Zyra vs Seraphine?
Zyra wins 49.8% of these games. With this many games the true rate is most likely between 43.8% and 55.8% (95% range).
- Expected
- 49.9% From both champions' overall Support win rates
- Matchup effect
- −0.1 pts Observed minus expected
- Sample
- 263 games Lane: Support
- vs patch 26.18
- −1.6 pts Within normal patch-to-patch noise
Lane: Support · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.19 · Sep 24 – Sep 28
Key takeaways
- Zyra vs Seraphine is an even matchup: Zyra wins 49.8% of 263 games, and the 95% range (43.8–55.8%) comfortably includes 50%.
- Both champions' overall Support win rates predict 49.9% for Zyra; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Neither side reliably wins the lane: the average gold difference at 15 minutes is 65, within the margin of error (261 games).
- Zyra players pick Grisly Mementos much less often against Seraphine: 22.9% of their other Support games, 16.7% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Zyra and Seraphine played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Zyra's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Zyra vs Seraphine Laning Stats
At 15 minutes
Whole-game averages
Zyra vs Seraphine Win Rate by Game Length
Zyra's win rate against Seraphine by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Zyra's results against Seraphine in short and long games are within the margin of error of each other.
Zyra vs Seraphine Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)EvenZyra gold at 15: +65
- First itemSeraphineZyra: 15.5 min · Seraphine: 14.0 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenZyra wins 45.9% of 98 games
- 30+ min gamesEvenZyra wins 53.2% of 156 games
What Zyra Changes Against Seraphine
Choices Zyra players make noticeably more or less often in this matchup than in their other Support games.
Grisly MementosRuneUsually22.9%vs Seraphine16.7%−6.1 pts38.6% WR here
Cosmic InsightRuneUsually13.6%vs Seraphine18.3%+4.7 pts47.9% WR here
Health (defense)Stat shardUsually9.0%vs Seraphine12.9%+3.9 pts61.8% WR here
Adaptive Force (flex)Stat shardUsually92.8%vs Seraphine89.4%−3.5 pts49.4% WR here
Best Zyra Build vs Seraphine
Usual Zyra build (Support)
81.8% win rate · 11 games
Against Seraphine
Not enough matchup-specific build data: only 11 of 88 Zyra games against Seraphine carried a complete build, which is too few to recommend an item path from. Use Zyra's standard build instead.
- Zyra usually completes Liandry's Torment first, at 15.5 min (median of 142 games).
- Seraphine usually completes Rylai's Crystal Scepter first, at 14.0 min (median of 87 games).
- Skill priority: E > Q > W — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Zyra Runes vs Seraphine
Plan your Zyra draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions

Zyra matchup data for League of Legends patch 26.19. The table below shows Zyra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zyra build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Zyra Matchups
Hardest for Zyra
Easiest for Zyra
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Zyra vs Seraphine FAQ - Patch 26.19
Who wins Zyra vs Seraphine?
Zyra vs Seraphine is an even matchup: Zyra wins 49.8% of 263 games, and the 95% range (43.8–55.8%) comfortably includes 50%.
What is Zyra's win rate against Seraphine?
Zyra wins 49.8% of 263 Support games against Seraphine on patch 26.19 (95% range 43.8–55.8%). Based on both champions' overall Support win rates, 49.9% would be expected.
Does Zyra counter Seraphine?
Not clearly. Zyra wins 49.8% of 263 games against Seraphine, and the 95% range (43.8–55.8%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Zyra or Seraphine?
Neither side reliably wins the lane: the average gold difference at 15 minutes is 65, within the margin of error (261 games).
Does Zyra outscale Seraphine?
There are too few games of each length to tell yet.
When is Seraphine strongest against Zyra?
Seraphine is measurably ahead in: First item.
What should Zyra build against Seraphine?
There are not enough games for a matchup-specific core, so use Zyra's usual Support core: Liandry's Torment, Rylai's Crystal Scepter, Rabadon's Deathcap.
What runes should Zyra use against Seraphine?
Arcane Comet with Sorcery and Domination — 47.7% over 65 games against Seraphine. The biggest change against Seraphine: Grisly Mementos (22.9% usually, 16.7% here).
