Spore Mind Curse

Is Spore Mind good in Slay the Spire 2?

Spore Mind is a curse Curse curse in Slay the Spire 2. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.

Across 29 recorded runs, decks running it win 20.7% of the time, comfortably clear of the 12.9% average, by 7.8%. It’s a more selective pick, turning up in just 0.2% of decks that could run it. On average it shows up 1.0 times in the decks that take it.

It performs best next to Ascender's Bane — together they post a +0.2% swing in win rate. At 1 energy, it’s upgraded in 0.0% of runs and usually joins the deck around floor 11.

That’s 6 wins, 23 deaths, and 0 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is The Kin Boss, which closes out 10.3% of its appearances. Read on for Spore Mind’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Curse run.

When to Pick Up Spore Mind

Spore Mind is strongest when it joins the deck in Act 1, where runs win 17.9% across 28 runs — one of 1 recorded pickup windows.

Win rate of runs by the act Spore Mind entered the deck. Acts that have not reached the sample floor show their run count only.

Best Cards to Pair with Spore Mind

Ranked by win-rate lift, Spore Mind performs best alongside Ascender's Bane (+0.2%).

Ascender's Bane+0.2%19 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Spore Mind Card Details

Spore Mind is a curse curse costing 1 energy; it’s upgraded in 0.0% of runs and usually picked up by floor 11.

What Ends Runs with Spore Mind

Spore Mind’s most common run-enders are The Kin Boss (10.3%), Byrdonis Elite (6.9%), and Phrog Parasite Elite (6.9%).

• The Kin Boss10.3% of runs
• Byrdonis Elite6.9% of runs
• Phrog Parasite Elite6.9% of runs
• Nibbits Normal6.9% of runs
• The Insatiable Boss6.9% of runs

See Also

Compare Spore Mind with the rest of the best Slay the Spire 2 cards, relics, and classes below.