Slay the Spire 2 Card Tier List

S-tier is led by Apotheosis, which dominates the meta with a 81.8% win rate on a 0.8% pick rate. They are followed by Beat Down (75.0%), Salvo (75.0%), Believe in You (68.8%), Catastrophe (62.5%), Flanking (62.5%), Enthralled (60.0%), and Eternal Armor (60.0%). The remaining 69 cards in this tier average a 47.4% win rate. These cards define the current meta and are the safest, highest-impact picks. In terms of popularity, Mad Science is the crowd favourite here at a 3.4% pick rate, while Salvo is slept on at just 0.3% — a strong S-tier pick flying under the radar.

B-tier is led by Dredge, which struggles with a 40.7% win rate on a 1.1% pick rate. They are followed by Exterminate (40.7%), Heirloom Hammer (40.7%), Shared Fate (40.7%), Squeeze (40.7%), Dirge (40.7%), Adrenaline (40.3%), and Assassinate (40.3%). The remaining 69 cards in this tier average a 37.4% win rate. These cards are balanced and fully viable with solid execution. In terms of popularity, Prepared is the crowd favourite here at a 8.7% pick rate, while Whistle is slept on at just 0.3% — a strong B-tier pick flying under the radar.

C-tier is led by Sentry Mode, which struggles with a 35.3% win rate on a 1.3% pick rate. They are followed by Inferno (35.1%), Skim (35.1%), Blur (35.1%), Delay (35.0%), Discovery (35.0%), Master Planner (35.0%), and Monarch's Gaze (35.0%). The remaining 95 cards in this tier average a 32.1% win rate. These cards are situational and need favourable matchups or team comps to shine. Despite the low ranking, Wisp stays popular at a 7.8% pick rate, meaning players overvalue it relative to its C-tier results, while Prophesize (0.4%) is more rightly avoided.

D-tier is led by Seeker Strike, which struggles with a 29.4% win rate on a 0.6% pick rate. They are followed by Molten Fist (29.4%), TURBO (29.3%), CHARGE!! (29.3%), Mirage (29.3%), Headbutt (29.1%), Juggernaut (28.9%), and Pagestorm (28.9%). The remaining 120 cards in this tier average a 26.1% win rate. These cards underperform against the current meta and take extra effort to win with. Despite the low ranking, Shrug It Off stays popular at a 7.6% pick rate, meaning players overvalue it relative to its D-tier results, while Protector (0.4%) is more rightly avoided.

F-tier is led by Terraforming, which struggles with a 23.1% win rate on a 0.5% pick rate. They are followed by Reaper Form (23.1%), Cloak of Stars (23.0%), Bludgeon (22.9%), Hegemony (22.6%), Anticipate (22.5%), Rattle (22.4%), and Outbreak (22.4%). The remaining 121 cards in this tier average a 16.6% win rate. These cards are the weakest options this patch and are best avoided in ranked. Despite the low ranking, Ascender's Bane stays popular at a 43.3% pick rate, meaning players overvalue it relative to its F-tier results, while Sacrifice (0.3%) is more rightly avoided.