Karthus - League of Legends Champion
Win Rate
49.3%
Pick Rate
1.3%

Karthusvs Mordekaiser

DMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 22, 2026
MethodologyData Methodology

Karthus vs Mordekaiser is a decisive matchup in LoL patch 26.7. Karthus wins with a 57.1% win rate (+14.3%) over Mordekaiser based on 7 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Mordekaiser matchup.

Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Mordekaiser - 57.1% win rateMordekaiser(57.1%)
Karthus - 57.1% win rate in this matchup
Karthus
57.1% WR
VS
Mordekaiser vs Karthus matchup - 42.9% win rate
Mordekaiser
42.9% WR

Who Wins the Karthus vs Mordekaiser Matchup?

Karthus wins the Karthus vs Mordekaiser matchup
Winner
Karthus
Matches: 7
57.1%
Win Rate
42.9%
2.0
CS / min
2.4
1,191
DMG / min
943
12,954
Gold / game
13,535
282
Heal / min
623
514
DMG Mitigated / min
1,683
0.5
CC / min
0.6
66.7%
Early Game WR
33.3%
50.0%
Late Game WR
50.0%

Karthus vs Mordekaiser Matchup Summary

The Karthus vs Mordekaiser matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Karthus wins with a 57.1% win rate compared to Mordekaiser's 42.9%, giving Karthus a 14.3 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Mordekaiser players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Mordekaiser leads by 1,511 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus players can confidently pick into Mordekaiser and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Mordekaiser away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Mordekaiser Laning Phase Breakdown

Mordekaiser wins the laning phase against Karthus in League of Legends

Mordekaiser is favored during the laning phase against Karthus, winning 4 out of 5 key stat categories. Mordekaiser holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.0Karthus
2.4Mordekaiser
Mordekaiser edges out Karthus by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Mordekaiser.
Damage
1,191Karthus
943Mordekaiser
Karthus heavily out-damages Mordekaiser by 248 DMG/min, dominating both short trades and all-in fights. Mordekaiser should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
12,954Karthus
13,535Mordekaiser
Mordekaiser earns 580 more gold per game than Karthus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Mordekaiser slightly faster item completions.
Utility
0.5Karthus
0.6Mordekaiser
Both Karthus and Mordekaiser provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
795Karthus
2,307Mordekaiser
Mordekaiser vastly out-sustains Karthus, healing and mitigating 1,511 more damage per minute. This massive durability gap means Mordekaiser can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karthus Build Against Mordekaiser

Sorcerer's Shoes is the optimal boots choice against Mordekaiser, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Mordekaiser are Liandry's Torment, Shadowflame and Void Staff. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Mordekaiser matchup.

Early Game vs Late Game

Early Game
Karthus
66.7%
+33.3% advantage
Karthus early game win rateKarthus66.7%
Mordekaiser early game win rateMordekaiser33.3%
Late Game
Karthus
50.0%
+0.0% advantage
Karthus late game win rateKarthus50.0%
Mordekaiser late game win rateMordekaiser50.0%

Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Mordekaiser. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Karthus at 50.0% win rate — only 0.0 points ahead of Mordekaiser. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Mordekaiser players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Karthus Runes Against Mordekaiser

Inspiration rune tree - Karthus primary runes vs MordekaiserInspiration
First Strike - best Karthus rune vs MordekaiserCash Back - best Karthus rune vs MordekaiserTriple Tonic - best Karthus rune vs MordekaiserCosmic Insight - best Karthus rune vs Mordekaiser
Sorcery rune tree - Karthus secondary runes vs MordekaiserSorcery
Gathering Storm - best Karthus rune vs MordekaiserAxiom Arcanist - best Karthus rune vs Mordekaiser
100.0% WR

Running Inspiration primary with Sorcery secondary allows Karthus to press their advantage against Mordekaiser, amplifying the strengths that make this a favorable matchup.


Karthus matchup data for League of Legends patch 26.7. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.78%411.51,24613,63464.7%37.5%
45.00%401.71,19914,67650.0%41.7%
37.84%371.81,20313,45342.9%34.8%
59.46%376.81,20414,13361.1%57.9%
58.33%361.41,18514,86346.1%65.2%
42.86%351.61,14713,92340.0%45.0%
44.12%341.41,12214,48658.3%36.4%
65.63%326.31,26613,64771.4%61.1%
50.00%281.61,25415,99971.4%42.9%
44.44%276.11,21913,94641.7%46.7%
59.26%276.01,24814,69160.0%58.8%
60.00%251.51,20814,13545.5%71.4%
63.64%222.01,41215,52085.7%53.3%
63.64%226.01,33115,66162.5%64.3%
57.89%191.21,11113,72737.5%72.7%
36.84%196.51,28014,54516.7%46.1%
42.11%191.51,29515,86340.0%42.9%
57.89%191.41,15014,33071.4%50.0%
47.06%176.41,29415,52850.0%46.1%
76.47%171.21,06613,39466.7%87.5%
47.06%171.81,19814,51350.0%46.1%
75.00%161.41,29814,71466.7%80.0%
56.25%161.51,14013,02250.0%62.5%
26.67%151.31,03412,14627.3%25.0%
33.33%152.11,14213,21320.0%40.0%
35.71%141.11,12013,85225.0%50.0%
38.46%131.21,08313,38916.7%57.1%
38.46%131.41,18614,42740.0%37.5%
23.08%132.21,01010,85522.2%25.0%
46.15%136.01,24613,80450.0%44.4%
53.85%137.11,16413,19242.9%66.7%
50.00%123.71,31914,92180.0%28.6%
50.00%121.21,22814,55325.0%62.5%
25.00%126.51,36414,04133.3%16.7%
83.33%121.41,23815,11766.7%88.9%
25.00%121.61,12615,19325.0%25.0%
66.67%127.31,53918,810100.0%60.0%
25.00%121.21,07613,8870.0%60.0%
50.00%121.31,03811,95450.0%50.0%
63.64%116.81,40515,26060.0%66.7%
63.64%112.91,09213,99266.7%62.5%
27.27%111.31,12512,25020.0%33.3%
18.18%111.51,18312,73025.0%14.3%
45.45%116.71,23014,91440.0%50.0%
70.00%105.91,26912,68760.0%80.0%
60.00%107.01,16813,68960.0%60.0%
60.00%101.41,38813,38660.0%60.0%
70.00%107.11,33314,53075.0%66.7%
33.33%97.31,21213,57820.0%50.0%
44.44%93.899013,717100.0%28.6%
22.22%96.81,08812,89120.0%25.0%
66.67%91.61,56915,98675.0%60.0%
66.67%91.81,22714,33780.0%50.0%
33.33%94.81,07213,64425.0%40.0%
50.00%86.71,22114,59460.0%33.3%
37.50%81.81,33816,668100.0%28.6%
42.86%72.11,10612,56733.3%50.0%
42.86%72.21,17211,38060.0%0.0%
42.86%72.01,37413,47750.0%33.3%
42.86%77.21,12512,97033.3%50.0%
71.43%75.71,05413,5520.0%100.0%
71.43%71.21,49615,8850.0%83.3%
14.29%72.91,23213,7160.0%33.3%
57.14%72.01,19112,95466.7%50.0%
42.86%72.11,19315,03550.0%40.0%
85.71%71.61,34617,646100.0%80.0%
57.14%72.81,23515,411100.0%40.0%
50.00%66.91,27912,34425.0%100.0%
66.67%61.31,38414,20166.7%66.7%
66.67%61.396311,486100.0%50.0%
33.33%65.41,55214,5320.0%33.3%
33.33%62.481311,29650.0%0.0%
66.67%64.01,15114,6630.0%80.0%
16.67%61.41,19215,1100.0%20.0%
50.00%61.61,26817,2400.0%60.0%
60.00%55.91,19113,24966.7%50.0%
40.00%51.61,10312,8790.0%66.7%
40.00%56.81,00311,9160.0%50.0%
60.00%55.11,47719,353100.0%50.0%
20.00%52.81,10312,98150.0%0.0%
60.00%53.17289,38375.0%0.0%
60.00%57.11,03414,8450.0%75.0%
20.00%58.21,15513,53650.0%0.0%
60.00%52.382213,48466.7%50.0%

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Karthus vs Mordekaiser - Frequently Asked Questions

How does Karthus do against Mordekaiser in League of Legends?

Karthus wins the Karthus vs Mordekaiser matchup with a 57.1% win rate compared to Mordekaiser's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.7.

How does Karthus do against Mordekaiser in the early game?

In the early game, Karthus has the advantage against Mordekaiser with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Mordekaiser in the late game?

In the late game, Karthus takes over the Karthus vs Mordekaiser matchup with a 50.0% win rate compared to 50.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Mordekaiser matchup?

Karthus wins the matchup against Mordekaiser with a 57.1% win rate in League of Legends patch 26.7. The 14.3 percentage point advantage means Karthus is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Karthus build against Mordekaiser?

The best Karthus build against Mordekaiser includes Liandry's Torment, Shadowflame, Void Staff with Sorcerer's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Mordekaiser?

The best Karthus runes against Mordekaiser use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Mordekaiser matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Mordekaiser?

Yes, Karthus has a favorable matchup against Mordekaiser with a 57.1% win rate. Karthus strongly counters Mordekaiser in lane based on current patch 26.7 data.

How do I play Karthus against Mordekaiser?

When playing Karthus against Mordekaiser, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.