Karthus - League of Legends Champion
Win Rate
52.9%
Pick Rate
0.9%

Karthusvs Warwick

SMage
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Karthus vs Warwick is a decisive matchup in LoL patch 26.14. Karthus wins with a 62.5% win rate (+25.0%) over Warwick based on 8 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Warwick matchup.

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Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 62.5% win rate in this matchup
Karthus
62.5% WR
VS
Warwick vs Karthus matchup - 37.5% win rate
Warwick
37.5% WR

Who Wins the Karthus vs Warwick Matchup?

Karthus wins the Karthus vs Warwick matchup
Winner
Karthus
Matches: 8
62.5%
Win Rate
37.5%
0.9
CS / min
0.8
1,032
DMG / min
397
11,643
Gold / game
10,622
309
Heal / min
595
434
DMG Mitigated / min
1,016
0.5
CC / min
0.7
66.7%
Early Game WR
33.3%
60.0%
Late Game WR
40.0%

Karthus vs Warwick Matchup Summary

The Karthus vs Warwick matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Karthus wins with a 62.5% win rate compared to Warwick's 37.5%, giving Karthus a 25.0 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Warwick players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Karthus leads by 635 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus players can confidently pick into Warwick and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Warwick away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Warwick Laning Phase Breakdown

Karthus wins the laning phase against Warwick in League of Legends

Karthus is favored during the laning phase against Warwick, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
0.9Karthus
0.8Warwick
Karthus and Warwick farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,032Karthus
397Warwick
Karthus heavily out-damages Warwick by 635 DMG/min, dominating both short trades and all-in fights. Warwick should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
11,643Karthus
10,622Warwick
Karthus generates a commanding 1,021 more gold per game than Warwick. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Warwick should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.5Karthus
0.7Warwick
Both Karthus and Warwick provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
743Karthus
1,610Warwick
Warwick vastly out-sustains Karthus, healing and mitigating 867 more damage per minute. This massive durability gap means Warwick can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karthus Build Against Warwick

Sorcerer's Shoes is the optimal boots choice against Warwick, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Warwick are Shadowflame, Void Staff and Rabadon's Deathcap. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Warwick matchup.

Early Game vs Late Game

Early Game
Karthus
66.7%
+33.3% advantage
Karthus early game win rateKarthus66.7%
Warwick early game win rateWarwick33.3%
Late Game
Karthus
60.0%
+20.0% advantage
Karthus late game win rateKarthus60.0%
Warwick late game win rateWarwick40.0%

Karthus dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Warwick. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karthus is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Warwick. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.

Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Warwick players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Karthus Runes Against Warwick

Domination rune tree - Karthus primary runes vs WarwickDomination
Dark Harvest - best Karthus rune vs WarwickCheap Shot - best Karthus rune vs WarwickGrisly Mementos - best Karthus rune vs WarwickUltimate Hunter - best Karthus rune vs Warwick
Sorcery rune tree - Karthus secondary runes vs WarwickSorcery
Axiom Arcanist - best Karthus rune vs WarwickGathering Storm - best Karthus rune vs Warwick
50.0% WR

Running Domination primary with Sorcery secondary allows Karthus to press their advantage against Warwick, amplifying the strengths that make this a favorable matchup.


Karthus matchup data for League of Legends patch 26.14. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
64.71%171.61,30714,66766.7%64.3%
61.54%131.41,26816,483100.0%54.5%
38.46%131.71,13714,45550.0%33.3%
53.85%131.289010,32966.7%42.9%
66.67%127.01,13812,77283.3%50.0%
50.00%126.81,06013,5260.0%66.7%
66.67%121.21,22315,65033.3%77.8%
54.55%111.493212,47820.0%83.3%
54.55%111.31,25216,58775.0%42.9%
30.00%101.21,05811,5090.0%60.0%
77.78%96.91,58016,28933.3%100.0%
77.78%91.11,46516,15150.0%85.7%
50.00%81.41,36413,21550.0%50.0%
62.50%82.11,29411,38950.0%75.0%
75.00%81.71,19514,4940.0%85.7%
62.50%80.91,03211,64366.7%60.0%
0.00%81.29159,7700.0%0.0%
100.00%81.31,14611,386100.0%100.0%
71.43%75.91,21011,767100.0%60.0%
42.86%73.81,20014,23566.7%25.0%
50.00%61.81,15115,1510.0%60.0%
50.00%66.81,05414,8930.0%60.0%
33.33%65.61,01311,5230.0%100.0%
66.67%66.31,18714,6750.0%80.0%
40.00%50.91,14013,258100.0%25.0%
60.00%56.31,26410,41750.0%66.7%
40.00%50.91,00613,487100.0%25.0%
20.00%55.393411,78633.3%0.0%
40.00%51.21,37916,148100.0%25.0%
20.00%54.39793,1650.0%100.0%
60.00%51.31,04614,377100.0%50.0%
25.00%41.41,38413,8210.0%33.3%
25.00%42.31,12113,8860.0%33.3%
100.00%21.51,21814,599100.0%100.0%

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Karthus vs Warwick - Frequently Asked Questions

How does Karthus do against Warwick in League of Legends?

Karthus wins the Karthus vs Warwick matchup with a 62.5% win rate compared to Warwick's 37.5%, a 25.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.14.

How does Karthus do against Warwick in the early game?

In the early game, Karthus has the advantage against Warwick with a 66.7% win rate versus 33.3%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Warwick in the late game?

In the late game, Karthus takes over the Karthus vs Warwick matchup with a 60.0% win rate compared to 40.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Warwick matchup?

Karthus wins the matchup against Warwick with a 62.5% win rate in League of Legends patch 26.14. The 25.0 percentage point advantage means Karthus is significantly favored in this lane matchup based on 8 games analyzed.

What is the best Karthus build against Warwick?

The best Karthus build against Warwick includes Shadowflame, Void Staff, Rabadon's Deathcap with Sorcerer's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Warwick?

The best Karthus runes against Warwick use the Domination primary tree with Sorcery secondary. This rune setup achieves a 50.0% win rate in the Karthus vs Warwick matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Warwick?

Yes, Karthus has a favorable matchup against Warwick with a 62.5% win rate. Karthus strongly counters Warwick in lane based on current patch 26.14 data.

How do I play Karthus against Warwick?

When playing Karthus against Warwick, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.