
Karthusvs Lee Sin
Karthus vs Lee Sin is a decisive matchup in LoL patch 26.11. Lee Sin wins with a 54.9% win rate (+9.8%) over Karthus based on 51 games. Lee Sin wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Lee Sin matchup.
Karthus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Karthus vs Lee Sin Matchup?

Karthus vs Lee Sin Matchup Summary
The Karthus vs Lee Sin matchup is a decisive matchup in League of Legends ranked play. Based on 51 recent matches analyzed, Lee Sin wins with a 54.9% win rate compared to Karthus's 45.1%, giving Lee Sin a 9.8 percentage point advantage. Game phase dynamics play a critical role here: Lee Sin controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lee Sin needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Lee Sin leads by 1,057 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lee Sin has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lee Sin overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karthus vs Lee Sin Laning Phase Breakdown
Karthus is favored during the laning phase against Lee Sin, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Karthus Build Against Lee Sin
Sorcerer's Shoes is the optimal boots choice against Lee Sin, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Lee Sin are Shadowflame, Zhonya's Hourglass and Rabadon's Deathcap. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Lee Sin. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Lee Sin matchup.
Early Game vs Late Game
Lee Sin dominates the early game (first 15 minutes) with a commanding 68.2% win rate — a 36.4 percentage point lead over Karthus. This lopsided early game means Lee Sin can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Karthus is far superior in the late game (25+ minutes), boasting a 55.2% win rate — 10.3 points above Lee Sin. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Lee Sin must aggressively press their early advantage and close out the game before Karthus reaches their scaling breakpoints. If Karthus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Karthus Runes Against Lee Sin
The Domination and Sorcery rune setup gives Karthus the best tools to compete against Lee Sin in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Karthus matchup data for League of Legends patch 26.11. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.09% | 55 | 1.4 | 1,030 | 12,957 | 47.8% | 50.0% | |
| 43.64% | 55 | 1.7 | 1,170 | 13,037 | 40.0% | 46.7% | |
| 45.10% | 51 | 1.6 | 1,057 | 13,346 | 31.8% | 55.2% | |
| 59.18% | 49 | 6.3 | 1,291 | 13,609 | 50.0% | 65.5% | |
| 52.08% | 48 | 1.5 | 1,259 | 14,655 | 47.1% | 54.8% | |
| 42.22% | 45 | 1.5 | 1,017 | 13,071 | 43.8% | 41.4% | |
| 37.78% | 45 | 1.3 | 1,027 | 12,768 | 40.9% | 34.8% | |
| 64.44% | 45 | 6.5 | 1,326 | 16,022 | 86.7% | 53.3% | |
| 50.00% | 42 | 6.6 | 1,197 | 13,070 | 66.7% | 33.3% | |
| 43.59% | 39 | 6.3 | 1,215 | 13,238 | 50.0% | 36.8% | |
| 57.89% | 38 | 1.4 | 1,263 | 13,760 | 53.3% | 60.9% | |
| 47.37% | 38 | 1.5 | 1,144 | 13,402 | 37.5% | 54.5% | |
| 34.21% | 38 | 1.9 | 1,067 | 12,867 | 40.0% | 30.4% | |
| 43.24% | 37 | 1.8 | 1,212 | 13,463 | 57.1% | 34.8% | |
| 38.24% | 34 | 7.0 | 1,247 | 13,842 | 33.3% | 42.1% | |
| 46.88% | 32 | 1.8 | 1,146 | 12,845 | 38.5% | 52.6% | |
| 43.33% | 30 | 1.8 | 1,294 | 14,569 | 58.3% | 33.3% | |
| 55.17% | 29 | 6.1 | 1,203 | 12,390 | 66.7% | 42.9% | |
| 46.43% | 28 | 1.4 | 1,030 | 12,474 | 53.3% | 38.5% | |
| 57.14% | 28 | 6.6 | 1,423 | 15,214 | 50.0% | 62.5% | |
| 40.74% | 27 | 1.3 | 1,335 | 15,992 | 16.7% | 47.6% | |
| 28.00% | 25 | 1.8 | 1,163 | 13,295 | 30.0% | 26.7% | |
| 66.67% | 24 | 1.6 | 1,146 | 14,337 | 75.0% | 58.3% | |
| 45.45% | 22 | 1.5 | 1,307 | 14,905 | 50.0% | 44.4% | |
| 66.67% | 21 | 2.2 | 1,201 | 13,572 | 77.8% | 58.3% | |
| 55.00% | 20 | 1.6 | 1,267 | 13,968 | 60.0% | 50.0% | |
| 68.42% | 19 | 5.6 | 1,496 | 16,092 | 100.0% | 60.0% | |
| 63.16% | 19 | 1.3 | 1,116 | 14,409 | 62.5% | 63.6% | |
| 38.89% | 18 | 1.5 | 1,448 | 14,535 | 42.9% | 36.4% | |
| 55.56% | 18 | 6.4 | 1,276 | 13,454 | 66.7% | 44.4% | |
| 72.22% | 18 | 5.1 | 1,121 | 11,322 | 60.0% | 87.5% | |
| 35.29% | 17 | 1.5 | 1,056 | 12,455 | 36.4% | 33.3% | |
| 52.94% | 17 | 1.3 | 1,370 | 15,161 | 57.1% | 50.0% | |
| 76.47% | 17 | 6.5 | 1,263 | 15,482 | 80.0% | 75.0% | |
| 47.06% | 17 | 1.5 | 960 | 12,244 | 44.4% | 50.0% | |
| 52.94% | 17 | 6.5 | 1,330 | 13,719 | 66.7% | 45.5% | |
| 43.75% | 16 | 1.4 | 1,244 | 15,497 | 50.0% | 41.7% | |
| 56.25% | 16 | 1.3 | 1,080 | 13,221 | 80.0% | 45.5% | |
| 53.33% | 15 | 5.4 | 1,373 | 13,678 | 75.0% | 45.5% | |
| 35.71% | 14 | 1.6 | 1,239 | 13,567 | 44.4% | 20.0% | |
| 28.57% | 14 | 6.7 | 1,359 | 11,934 | 50.0% | 12.5% | |
| 42.86% | 14 | 2.4 | 1,250 | 14,777 | 40.0% | 44.4% | |
| 50.00% | 14 | 1.6 | 1,082 | 15,541 | 25.0% | 60.0% | |
| 69.23% | 13 | 6.5 | 1,305 | 13,965 | 57.1% | 83.3% | |
| 61.54% | 13 | 6.5 | 1,256 | 12,939 | 60.0% | 62.5% | |
| 53.85% | 13 | 2.5 | 1,052 | 12,276 | 75.0% | 44.4% | |
| 58.33% | 12 | 5.9 | 1,027 | 10,269 | 57.1% | 60.0% | |
| 83.33% | 12 | 1.3 | 1,229 | 13,183 | 80.0% | 85.7% | |
| 50.00% | 12 | 5.4 | 1,340 | 14,967 | 75.0% | 37.5% | |
| 45.45% | 11 | 1.4 | 1,031 | 13,145 | 57.1% | 25.0% | |
| 72.73% | 11 | 1.6 | 1,027 | 12,997 | 100.0% | 57.1% | |
| 27.27% | 11 | 5.9 | 1,132 | 13,232 | 0.0% | 42.9% | |
| 30.00% | 10 | 3.2 | 1,059 | 13,472 | 25.0% | 33.3% | |
| 70.00% | 10 | 7.4 | 1,271 | 15,568 | 100.0% | 57.1% | |
| 70.00% | 10 | 2.9 | 1,144 | 15,271 | 100.0% | 62.5% | |
| 50.00% | 10 | 7.2 | 1,138 | 12,216 | 50.0% | 50.0% | |
| 40.00% | 10 | 2.9 | 1,376 | 15,578 | 0.0% | 44.4% | |
| 55.56% | 9 | 5.5 | 1,266 | 13,151 | 50.0% | 60.0% | |
| 33.33% | 9 | 4.9 | 927 | 10,925 | 20.0% | 50.0% | |
| 44.44% | 9 | 6.2 | 1,072 | 10,467 | 33.3% | 66.7% | |
| 55.56% | 9 | 3.3 | 1,212 | 14,875 | 100.0% | 42.9% | |
| 55.56% | 9 | 1.4 | 1,252 | 15,076 | 100.0% | 42.9% | |
| 77.78% | 9 | 2.9 | 1,165 | 14,153 | 66.7% | 83.3% | |
| 33.33% | 9 | 2.1 | 1,195 | 13,834 | 33.3% | 33.3% | |
| 87.50% | 8 | 1.3 | 1,113 | 14,337 | 80.0% | 100.0% | |
| 25.00% | 8 | 1.3 | 1,285 | 13,222 | 50.0% | 16.7% | |
| 87.50% | 8 | 6.4 | 1,182 | 14,464 | 50.0% | 100.0% | |
| 75.00% | 8 | 1.7 | 1,650 | 16,965 | 50.0% | 83.3% | |
| 75.00% | 8 | 6.7 | 1,197 | 15,023 | 75.0% | 75.0% | |
| 62.50% | 8 | 2.0 | 991 | 13,519 | 100.0% | 50.0% | |
| 37.50% | 8 | 1.7 | 996 | 13,524 | 0.0% | 50.0% | |
| 57.14% | 7 | 6.3 | 1,632 | 17,174 | 100.0% | 50.0% | |
| 42.86% | 7 | 2.9 | 1,108 | 11,950 | 25.0% | 66.7% | |
| 14.29% | 7 | 1.1 | 907 | 12,626 | 25.0% | 0.0% | |
| 71.43% | 7 | 6.9 | 1,202 | 14,284 | 50.0% | 80.0% | |
| 85.71% | 7 | 5.5 | 1,332 | 17,108 | 0.0% | 85.7% | |
| 42.86% | 7 | 4.1 | 1,210 | 13,964 | 0.0% | 50.0% | |
| 28.57% | 7 | 6.0 | 1,442 | 13,367 | 0.0% | 40.0% | |
| 57.14% | 7 | 7.0 | 1,427 | 13,690 | 33.3% | 75.0% | |
| 57.14% | 7 | 2.4 | 1,124 | 12,107 | 40.0% | 100.0% | |
| 85.71% | 7 | 1.0 | 1,062 | 14,104 | 50.0% | 100.0% | |
| 50.00% | 6 | 7.1 | 1,388 | 12,743 | 50.0% | 50.0% | |
| 33.33% | 6 | 6.8 | 1,144 | 11,486 | 0.0% | 66.7% | |
| 66.67% | 6 | 4.2 | 1,440 | 15,135 | 100.0% | 60.0% | |
| 33.33% | 6 | 2.3 | 965 | 9,779 | 0.0% | 50.0% | |
| 33.33% | 6 | 2.5 | 1,074 | 12,120 | 50.0% | 0.0% | |
| 33.33% | 6 | 6.6 | 1,316 | 11,448 | 0.0% | 66.7% | |
| 16.67% | 6 | 5.8 | 1,303 | 13,270 | 0.0% | 25.0% | |
| 50.00% | 6 | 2.5 | 1,437 | 16,735 | 0.0% | 75.0% | |
| 20.00% | 5 | 6.3 | 1,409 | 13,939 | 0.0% | 33.3% | |
| 40.00% | 5 | 5.3 | 798 | 6,518 | 0.0% | 100.0% | |
| 40.00% | 5 | 1.1 | 1,418 | 14,804 | 0.0% | 50.0% | |
| 40.00% | 5 | 3.4 | 1,190 | 15,035 | 0.0% | 50.0% | |
| 60.00% | 5 | 4.6 | 1,656 | 13,732 | 66.7% | 50.0% | |
| 80.00% | 5 | 6.7 | 1,331 | 10,470 | 66.7% | 100.0% | |
| 60.00% | 5 | 2.0 | 1,292 | 14,405 | 100.0% | 50.0% | |
| 20.00% | 5 | 6.0 | 1,206 | 10,846 | 33.3% | 0.0% | |
| 40.00% | 5 | 6.7 | 1,012 | 12,710 | 0.0% | 50.0% | |
| 40.00% | 5 | 6.3 | 1,482 | 13,690 | 100.0% | 25.0% | |
| 60.00% | 5 | 5.9 | 1,400 | 13,383 | 66.7% | 50.0% | |
| 40.00% | 5 | 6.5 | 1,189 | 9,677 | 25.0% | 100.0% | |
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Karthus vs Lee Sin - Frequently Asked Questions
How does Karthus do against Lee Sin in League of Legends?
Lee Sin wins the Karthus vs Lee Sin matchup with a 54.9% win rate compared to Karthus's 45.1%, a 9.8 percentage point difference. This data is based on 51 recent ranked games in patch 26.11.
How does Karthus do against Lee Sin in the early game?
In the early game, Lee Sin has the advantage against Karthus with a 68.2% win rate versus 31.8%. Lee Sin players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karthus do against Lee Sin in the late game?
In the late game, Karthus takes over the Karthus vs Lee Sin matchup with a 55.2% win rate compared to 44.8%. Karthus scales better into team fights and objective contests after 25 minutes.
Who wins the Karthus vs Lee Sin matchup?
Lee Sin wins the matchup against Karthus with a 54.9% win rate in League of Legends patch 26.11. The 9.8 percentage point advantage means Lee Sin is significantly favored in this lane matchup based on 51 games analyzed.
What is the best Karthus build against Lee Sin?
The best Karthus build against Lee Sin includes Shadowflame, Zhonya's Hourglass, Rabadon's Deathcap with Sorcerer's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Karthus runes against Lee Sin?
The best Karthus runes against Lee Sin use the Domination primary tree with Sorcery secondary. This rune setup achieves a 53.3% win rate in the Karthus vs Lee Sin matchup. See the full rune breakdown in the matchup comparison above.
Does Karthus counter Lee Sin?
No, Karthus struggles against Lee Sin with only a 45.1% win rate. Lee Sin has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Lee Sin's lead.
How do I play Karthus against Lee Sin?
When playing Karthus against Lee Sin, play cautiously and avoid Lee Sin's power spikes. Focus on safe farming — you outscale Lee Sin in the late game. Use the matchup-specific build and runes above to optimize your chances.
