
KarthusRunes
Best Karthus runes for LoL Patch 26.7 - Dark Harvest from the Domination tree with Precision secondary (66.7% WR, 0.6% pick rate). Karthus's optimal primary runes are Dark Harvest, Cheap Shot, Grisly Mementos, Ultimate Hunter. Secondary tree: Triumph, Last Stand.
Primary Tree
Domination
Dark HarvestDamaging a Champion below 50% health deals
Dark Harvest damage: 30 (+11 damage per soul) (+0.1 bonus AD) (+0.05 AP)
Cooldown: 35s (resets to 1.0s on takedown)
Cheap ShotDamaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).
Cooldown: 4s
Grisly MementosCollect 1 memento on champion
Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.
Ultimate HunterYour ultimate gains
TriumphTakedowns restore 5% of your missing health, 2.5% of your max health, and grant an additional 20 gold.
'The most dangerous game brings the greatest glory.'
—Noxian Reckoner
Last StandDeal 5% - 11% increased damage to champions while you are below 60% health. Max damage gained at 30% health.
Primary Tree
Sorcery
Summon AeryDamaging enemy champions with basic attacks or abilities sends Aery to them, dealing 10 - 50 based on level (+
Empowering or protecting allies with abilities sends Aery to them, shielding them for 30 - 100 based on level (+
Aery cannot be sent out again until she returns to you.
Axiom ArcanistYour Ultimate has 12% increased damage, healing, and shielding.
(AoE damage is reduced to a 8% increase)
Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown by 7%.
TranscendenceGain bonuses upon reaching the following levels:
Level 5: +5
Level 8: +5
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
ScorchYour next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.
Cooldown: 10s
Presence of MindDamaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.
Takedowns restore 15% of your maximum mana or energy.
Cooldown for damage restoration: 8s
Last StandDeal 5% - 11% increased damage to champions while you are below 60% health. Max damage gained at 30% health.
Zyra
Lux
Fiddlesticks
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Karthus Runes - Frequently Asked Questions
What are the best Karthus runes in patch 26.7?
The best Karthus runes in patch 26.7 use the Domination tree with Dark Harvest, Cheap Shot, Grisly Mementos, and Ultimate Hunter, and the Precision tree with Triumph and Last Stand. This rune setup achieves a 66.7% win rate with a 0.6% pick rate.
What is the win rate for Karthus's best rune page?
Karthus's best rune page has a 66.7% win rate in patch 26.7, which is +17.4% compared to Karthus's average win rate. This rune setup has a 0.6% pick rate among Karthus players.
What keystone should I use on Karthus?
Dark Harvest from the Domination tree is the best keystone rune for Karthus in patch 26.7. This keystone synergizes well with Karthus's kit and provides a 66.7% win rate.
What is Karthus's primary rune tree?
Karthus's primary rune tree is Domination. The optimal Domination runes for Karthus are Dark Harvest, Cheap Shot, Grisly Mementos, and Ultimate Hunter, with Dark Harvest being the keystone of choice.
What is Karthus's secondary rune tree?
Karthus's best secondary rune tree is Precision. The recommended Precision runes are Triumph and Last Stand, which complement Karthus's Domination primary tree.
What are alternative rune setups for Karthus?
An alternative Karthus rune setup uses alternative keystone from the Sorcery tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Karthus's runes?
Karthus's top rune page has a 0.6% pick rate in patch 26.7. This indicates that 0.6% of Karthus players use the Dark Harvest setup with Domination and Precision trees.


























