Karthus - League of Legends Champion
Win Rate
50.0%
Pick Rate
1.1%

Karthusvs Kayn

CMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 4, 2026
MethodologyData Methodology

Karthus vs Kayn is a very close matchup in LoL patch 26.11. Kayn wins with a 50.9% win rate (+1.8%) over Karthus based on 55 games. Kayn wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Kayn matchup.

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Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 49.1% win rate in this matchup
Karthus
49.1% WR
VS
Kayn vs Karthus matchup - 50.9% win rate
Kayn
50.9% WR

Who Wins the Karthus vs Kayn Matchup?

Kayn wins the Karthus vs Kayn matchup
Winner
Kayn
Matches: 55
49.1%
Win Rate
50.9%
1.4
CS / min
1.0
1,030
DMG / min
762
12,957
Gold / game
13,074
289
Heal / min
493
440
DMG Mitigated / min
833
0.6
CC / min
0.4
47.8%
Early Game WR
52.2%
50.0%
Late Game WR
50.0%

Karthus vs Kayn Matchup Summary

The Karthus vs Kayn matchup is a very close matchup in League of Legends ranked play. Based on 55 recent matches analyzed, Kayn wins with a 50.9% win rate compared to Karthus's 49.1%, giving Kayn a 1.8 percentage point advantage. Game phase dynamics play a critical role here: Kayn controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Kayn needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Kayn leads by 597 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Kayn is slightly favored, Karthus can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Kayn's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Kayn Laning Phase Breakdown

Karthus wins the laning phase against Kayn in League of Legends

Karthus is favored during the laning phase against Kayn, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
1.4Karthus
1.0Kayn
Karthus edges out Kayn by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Karthus.
Damage
1,030Karthus
762Kayn
Karthus heavily out-damages Kayn by 269 DMG/min, dominating both short trades and all-in fights. Kayn should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
12,957Karthus
13,074Kayn
Karthus and Kayn generate nearly equal gold per game, with just a 117 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.6Karthus
0.4Kayn
Both Karthus and Kayn provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
729Karthus
1,326Kayn
Kayn vastly out-sustains Karthus, healing and mitigating 597 more damage per minute. This massive durability gap means Kayn can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karthus Build Against Kayn

Sorcerer's Shoes is the optimal boots choice against Kayn, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Kayn are Liandry's Torment, Shadowflame and Blackfire Torch. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 3 games — well above average and making it the top item path against Kayn. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Kayn matchup.

Early Game vs Late Game

Early Game
Kayn
52.2%
+4.3% advantage
Karthus early game win rateKarthus47.8%
Kayn early game win rateKayn52.2%
Late Game
Karthus
50.0%
+0.0% advantage
Karthus late game win rateKarthus50.0%
Kayn late game win rateKayn50.0%

During the early laning phase (first 15 minutes), Kayn has a meaningful 52.2% win rate, outperforming Karthus by 4.3 percentage points. Kayn players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Late game (25+ minutes) is equally balanced, with Karthus at 50.0% win rate — only 0.0 points ahead of Kayn. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Kayn has the edge early, but Karthus gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Karthus Runes Against Kayn

Sorcery rune tree - Karthus primary runes vs KaynSorcery
Deathfire Touch - best Karthus rune vs KaynAxiom Arcanist - best Karthus rune vs KaynAbsolute Focus - best Karthus rune vs KaynGathering Storm - best Karthus rune vs Kayn
Precision rune tree - Karthus secondary runes vs KaynPrecision
Triumph - best Karthus rune vs KaynCoup de Grace - best Karthus rune vs Kayn
100.0% WR

The Sorcery primary with Precision secondary combination helps Karthus maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Kayn.


Karthus matchup data for League of Legends patch 26.11. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.09%551.41,03012,95747.8%50.0%
43.64%551.71,17013,03740.0%46.7%
45.10%511.61,05713,34631.8%55.2%
59.18%496.31,29113,60950.0%65.5%
52.08%481.51,25914,65547.1%54.8%
42.22%451.51,01713,07143.8%41.4%
37.78%451.31,02712,76840.9%34.8%
64.44%456.51,32616,02286.7%53.3%
50.00%426.61,19713,07066.7%33.3%
43.59%396.31,21513,23850.0%36.8%
57.89%381.41,26313,76053.3%60.9%
47.37%381.51,14413,40237.5%54.5%
34.21%381.91,06712,86740.0%30.4%
43.24%371.81,21213,46357.1%34.8%
38.24%347.01,24713,84233.3%42.1%
46.88%321.81,14612,84538.5%52.6%
43.33%301.81,29414,56958.3%33.3%
55.17%296.11,20312,39066.7%42.9%
46.43%281.41,03012,47453.3%38.5%
57.14%286.61,42315,21450.0%62.5%
40.74%271.31,33515,99216.7%47.6%
28.00%251.81,16313,29530.0%26.7%
66.67%241.61,14614,33775.0%58.3%
45.45%221.51,30714,90550.0%44.4%
66.67%212.21,20113,57277.8%58.3%
55.00%201.61,26713,96860.0%50.0%
68.42%195.61,49616,092100.0%60.0%
63.16%191.31,11614,40962.5%63.6%
38.89%181.51,44814,53542.9%36.4%
55.56%186.41,27613,45466.7%44.4%
72.22%185.11,12111,32260.0%87.5%
35.29%171.51,05612,45536.4%33.3%
52.94%171.31,37015,16157.1%50.0%
76.47%176.51,26315,48280.0%75.0%
47.06%171.596012,24444.4%50.0%
52.94%176.51,33013,71966.7%45.5%
43.75%161.41,24415,49750.0%41.7%
56.25%161.31,08013,22180.0%45.5%
53.33%155.41,37313,67875.0%45.5%
35.71%141.61,23913,56744.4%20.0%
28.57%146.71,35911,93450.0%12.5%
42.86%142.41,25014,77740.0%44.4%
50.00%141.61,08215,54125.0%60.0%
69.23%136.51,30513,96557.1%83.3%
61.54%136.51,25612,93960.0%62.5%
53.85%132.51,05212,27675.0%44.4%
58.33%125.91,02710,26957.1%60.0%
83.33%121.31,22913,18380.0%85.7%
50.00%125.41,34014,96775.0%37.5%
45.45%111.41,03113,14557.1%25.0%
72.73%111.61,02712,997100.0%57.1%
27.27%115.91,13213,2320.0%42.9%
30.00%103.21,05913,47225.0%33.3%
70.00%107.41,27115,568100.0%57.1%
70.00%102.91,14415,271100.0%62.5%
50.00%107.21,13812,21650.0%50.0%
40.00%102.91,37615,5780.0%44.4%
55.56%95.51,26613,15150.0%60.0%
33.33%94.992710,92520.0%50.0%
44.44%96.21,07210,46733.3%66.7%
55.56%93.31,21214,875100.0%42.9%
55.56%91.41,25215,076100.0%42.9%
77.78%92.91,16514,15366.7%83.3%
33.33%92.11,19513,83433.3%33.3%
87.50%81.31,11314,33780.0%100.0%
25.00%81.31,28513,22250.0%16.7%
87.50%86.41,18214,46450.0%100.0%
75.00%81.71,65016,96550.0%83.3%
75.00%86.71,19715,02375.0%75.0%
62.50%82.099113,519100.0%50.0%
37.50%81.799613,5240.0%50.0%
57.14%76.31,63217,174100.0%50.0%
42.86%72.91,10811,95025.0%66.7%
14.29%71.190712,62625.0%0.0%
71.43%76.91,20214,28450.0%80.0%
85.71%75.51,33217,1080.0%85.7%
42.86%74.11,21013,9640.0%50.0%
28.57%76.01,44213,3670.0%40.0%
57.14%77.01,42713,69033.3%75.0%
57.14%72.41,12412,10740.0%100.0%
85.71%71.01,06214,10450.0%100.0%
50.00%67.11,38812,74350.0%50.0%
33.33%66.81,14411,4860.0%66.7%
66.67%64.21,44015,135100.0%60.0%
33.33%62.39659,7790.0%50.0%
33.33%62.51,07412,12050.0%0.0%
33.33%66.61,31611,4480.0%66.7%
16.67%65.81,30313,2700.0%25.0%
50.00%62.51,43716,7350.0%75.0%
20.00%56.31,40913,9390.0%33.3%
40.00%55.37986,5180.0%100.0%
40.00%51.11,41814,8040.0%50.0%
40.00%53.41,19015,0350.0%50.0%
60.00%54.61,65613,73266.7%50.0%
80.00%56.71,33110,47066.7%100.0%
60.00%52.01,29214,405100.0%50.0%
20.00%56.01,20610,84633.3%0.0%
40.00%56.71,01212,7100.0%50.0%
40.00%56.31,48213,690100.0%25.0%
60.00%55.91,40013,38366.7%50.0%
40.00%56.51,1899,67725.0%100.0%

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Karthus vs Kayn - Frequently Asked Questions

How does Karthus do against Kayn in League of Legends?

Kayn wins the Karthus vs Kayn matchup with a 50.9% win rate compared to Karthus's 49.1%, a 1.8 percentage point difference. This data is based on 55 recent ranked games in patch 26.11.

How does Karthus do against Kayn in the early game?

In the early game, Kayn has the advantage against Karthus with a 52.2% win rate versus 47.8%. Kayn players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Kayn in the late game?

In the late game, Karthus takes over the Karthus vs Kayn matchup with a 50.0% win rate compared to 50.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Kayn matchup?

Kayn wins the matchup against Karthus with a 50.9% win rate in League of Legends patch 26.11. The 1.8 percentage point advantage means Kayn is slightly favored in this lane matchup based on 55 games analyzed.

What is the best Karthus build against Kayn?

The best Karthus build against Kayn includes Liandry's Torment, Shadowflame, Blackfire Torch with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Kayn?

The best Karthus runes against Kayn use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Kayn matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Kayn?

No, Karthus struggles against Kayn with only a 49.1% win rate. Kayn has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Kayn's lead.

How do I play Karthus against Kayn?

When playing Karthus against Kayn, play cautiously and avoid Kayn's power spikes. Focus on safe farming — you outscale Kayn in the late game. Use the matchup-specific build and runes above to optimize your chances.