Karthusvs Kayn
Karthus vs Kayn is a decisive matchup in LoL patch 26.4. Kayn wins with a 70.4% win rate (+40.7%) over Karthus based on 54 games. Kayn holds the advantage in both the early and late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Kayn matchup.
Karthus Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Kayn(29.6%)Who Wins the Karthus vs Kayn Matchup?
Karthus vs Kayn Matchup Summary
The Karthus vs Kayn matchup is a decisive matchup in League of Legends ranked play. Based on 54 recent matches analyzed, Kayn wins with a 70.4% win rate compared to Karthus's 29.6%, giving Kayn a 40.7 percentage point advantage. Kayn dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Karthus players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Kayn leads by 712 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Kayn has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Kayn overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karthus vs Kayn Laning Phase Breakdown
Karthus is favored during the laning phase against Kayn, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.
Best Karthus Build Against Kayn
Sorcerer's Shoes is the optimal boots choice against Kayn, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Kayn are Shadowflame, Rabadon's Deathcap and Blackfire Torch. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 6 games, proving it to be a reliable item path when facing Kayn. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Kayn matchup.
Early Game vs Late Game
Karthus37.0%Kayn63.0%Karthus22.2%Kayn77.8%Kayn dominates the early game (first 15 minutes) with a commanding 63.0% win rate — a 25.9 percentage point lead over Karthus. This lopsided early game means Kayn can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Kayn is far superior in the late game (25+ minutes), boasting a 77.8% win rate — 55.6 points above Karthus. Extended games heavily favor Kayn, whose kit and scaling make them a dominant force in team fights and objective control.
Kayn holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Karthus players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Karthus Runes Against Kayn
Domination
Precision
The Domination and Precision rune setup gives Karthus the best tools to compete against Kayn in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Karthus matchup data for League of Legends patch 26.4. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 46.15% | 91 | 1.3 | 1,120 | 14,205 | 43.6% | 48.1% | |
| 53.75% | 80 | 1.4 | 1,170 | 13,996 | 51.4% | 55.8% | |
| 50.82% | 61 | 1.5 | 1,057 | 13,986 | 46.9% | 55.2% | |
| 29.63% | 54 | 1.4 | 1,016 | 12,846 | 37.0% | 22.2% | |
| 40.74% | 54 | 1.2 | 1,000 | 13,576 | 52.0% | 31.0% | |
| 52.83% | 53 | 1.3 | 1,102 | 14,431 | 38.9% | 60.0% | |
| 50.00% | 45 | 1.5 | 1,190 | 13,930 | 33.3% | 65.2% | |
| 40.91% | 45 | 1.8 | 1,249 | 12,875 | 30.4% | 52.4% | |
| 45.45% | 44 | 1.5 | 1,191 | 15,818 | 57.1% | 40.0% | |
| 52.50% | 40 | 1.4 | 1,236 | 14,936 | 35.3% | 65.2% | |
| 32.43% | 38 | 2.2 | 1,191 | 13,009 | 17.6% | 45.0% | |
| 34.21% | 38 | 1.7 | 1,178 | 13,809 | 43.8% | 27.3% | |
| 45.71% | 35 | 1.4 | 1,164 | 15,700 | 25.0% | 51.9% | |
| 42.86% | 35 | 2.3 | 1,167 | 13,806 | 47.4% | 37.5% | |
| 62.50% | 33 | 1.5 | 1,089 | 14,674 | 53.3% | 70.6% | |
| 48.48% | 33 | 1.4 | 1,171 | 15,069 | 72.7% | 36.4% | |
| 65.63% | 33 | 1.4 | 1,216 | 14,022 | 75.0% | 60.0% | |
| 62.50% | 32 | 6.5 | 1,189 | 14,626 | 55.6% | 71.4% | |
| 64.52% | 31 | 2.8 | 1,253 | 15,724 | 50.0% | 71.4% | |
| 48.39% | 31 | 2.1 | 1,175 | 15,097 | 44.4% | 50.0% | |
| 53.33% | 30 | 1.3 | 1,210 | 14,877 | 60.0% | 50.0% | |
| 46.67% | 30 | 1.4 | 1,191 | 14,728 | 25.0% | 61.1% | |
| 40.00% | 30 | 1.5 | 1,118 | 13,173 | 25.0% | 57.1% | |
| 44.83% | 29 | 1.8 | 1,241 | 15,383 | 44.4% | 45.0% | |
| 39.29% | 28 | 2.5 | 1,075 | 12,064 | 26.7% | 53.9% | |
| 35.71% | 28 | 7.1 | 1,290 | 14,721 | 44.4% | 31.6% | |
| 57.14% | 28 | 7.1 | 1,297 | 15,280 | 41.7% | 68.8% | |
| 51.85% | 27 | 1.4 | 1,228 | 14,684 | 46.7% | 58.3% | |
| 44.00% | 25 | 1.6 | 1,119 | 13,324 | 50.0% | 40.0% | |
| 72.00% | 25 | 6.3 | 1,277 | 13,059 | 66.7% | 80.0% | |
| 56.52% | 24 | 1.4 | 1,191 | 15,351 | 40.0% | 69.2% | |
| 52.17% | 24 | 2.6 | 1,124 | 13,878 | 54.5% | 50.0% | |
| 43.48% | 24 | 3.2 | 1,399 | 17,314 | 33.3% | 45.0% | |
| 63.64% | 23 | 1.6 | 1,136 | 14,340 | 70.0% | 58.3% | |
| 52.17% | 23 | 1.8 | 1,071 | 12,130 | 52.9% | 50.0% | |
| 50.00% | 22 | 2.7 | 1,114 | 14,470 | 33.3% | 61.5% | |
| 54.55% | 22 | 1.4 | 1,010 | 12,483 | 53.9% | 55.6% | |
| 63.16% | 21 | 6.7 | 1,136 | 14,480 | 55.6% | 70.0% | |
| 52.38% | 21 | 1.8 | 1,180 | 14,647 | 60.0% | 45.5% | |
| 31.58% | 19 | 1.5 | 1,146 | 15,290 | 33.3% | 30.8% | |
| 72.22% | 18 | 1.5 | 1,113 | 15,767 | 85.7% | 63.6% | |
| 38.89% | 18 | 6.6 | 1,527 | 15,772 | 50.0% | 30.0% | |
| 55.56% | 18 | 7.0 | 1,222 | 14,455 | 50.0% | 62.5% | |
| 55.56% | 18 | 6.4 | 1,391 | 14,924 | 50.0% | 58.3% | |
| 35.29% | 17 | 1.2 | 1,076 | 13,707 | 12.5% | 55.6% | |
| 64.71% | 17 | 1.3 | 1,093 | 14,461 | 50.0% | 72.7% | |
| 58.82% | 17 | 6.8 | 1,212 | 13,672 | 40.0% | 66.7% | |
| 25.00% | 16 | 6.1 | 1,419 | 13,997 | 33.3% | 14.3% | |
| 37.50% | 16 | 4.7 | 957 | 10,619 | 50.0% | 25.0% | |
| 50.00% | 15 | 2.6 | 1,404 | 16,464 | 60.0% | 44.4% | |
| 28.57% | 15 | 1.7 | 1,341 | 13,512 | 50.0% | 12.5% | |
| 26.67% | 15 | 3.0 | 1,164 | 15,023 | 50.0% | 18.2% | |
| 50.00% | 14 | 6.6 | 1,299 | 14,190 | 33.3% | 80.0% | |
| 50.00% | 14 | 6.9 | 1,256 | 14,709 | 60.0% | 44.4% | |
| 21.43% | 14 | 1.9 | 1,356 | 14,816 | 25.0% | 20.0% | |
| 42.86% | 14 | 0.9 | 943 | 12,127 | 40.0% | 50.0% | |
| 42.86% | 14 | 1.3 | 954 | 13,811 | 80.0% | 22.2% | |
| 64.29% | 14 | 1.2 | 1,154 | 15,286 | 66.7% | 62.5% | |
| 61.54% | 13 | 2.7 | 1,141 | 12,855 | 50.0% | 80.0% | |
| 53.85% | 13 | 6.4 | 1,420 | 14,719 | 57.1% | 50.0% | |
| 30.77% | 13 | 1.8 | 1,063 | 12,255 | 25.0% | 40.0% | |
| 30.77% | 13 | 6.0 | 1,072 | 11,463 | 37.5% | 20.0% | |
| 54.55% | 13 | 6.8 | 1,357 | 16,646 | 100.0% | 44.4% | |
| 61.54% | 13 | 2.4 | 1,135 | 12,877 | 42.9% | 83.3% | |
| 66.67% | 13 | 3.1 | 1,264 | 16,012 | 50.0% | 83.3% | |
| 66.67% | 12 | 5.8 | 1,295 | 15,328 | 33.3% | 77.8% | |
| 72.73% | 11 | 1.1 | 1,272 | 16,663 | 100.0% | 70.0% | |
| 45.45% | 11 | 7.0 | 1,245 | 14,822 | 50.0% | 42.9% | |
| 72.73% | 11 | 6.0 | 1,333 | 13,295 | 83.3% | 60.0% | |
| 54.55% | 11 | 2.2 | 1,177 | 15,165 | 33.3% | 62.5% | |
| 36.36% | 11 | 5.6 | 1,235 | 16,021 | 50.0% | 33.3% | |
| 40.00% | 10 | 6.0 | 1,133 | 10,076 | 37.5% | 50.0% | |
| 50.00% | 10 | 1.8 | 1,217 | 15,398 | 100.0% | 37.5% | |
| 40.00% | 10 | 4.5 | 1,103 | 11,537 | 0.0% | 80.0% | |
| 40.00% | 10 | 6.4 | 1,130 | 11,079 | 50.0% | 33.3% | |
| 22.22% | 9 | 1.5 | 1,222 | 14,725 | 0.0% | 28.6% | |
| 22.22% | 9 | 6.1 | 1,359 | 12,463 | 0.0% | 40.0% | |
| 44.44% | 9 | 0.9 | 1,261 | 15,746 | 33.3% | 50.0% | |
| 55.56% | 9 | 7.1 | 1,174 | 15,106 | 33.3% | 66.7% | |
| 62.50% | 8 | 7.3 | 1,187 | 13,084 | 80.0% | 33.3% | |
| 37.50% | 8 | 4.0 | 1,183 | 14,741 | 0.0% | 42.9% | |
| 25.00% | 8 | 1.9 | 1,167 | 15,051 | 33.3% | 20.0% | |
| 50.00% | 8 | 6.2 | 1,029 | 12,254 | 50.0% | 50.0% | |
| 57.14% | 7 | 7.8 | 1,102 | 13,814 | 60.0% | 50.0% | |
| 42.86% | 7 | 2.3 | 1,114 | 14,123 | 0.0% | 50.0% | |
| 28.57% | 7 | 0.7 | 1,441 | 14,470 | 0.0% | 28.6% | |
| 42.86% | 7 | 6.5 | 1,288 | 16,051 | 0.0% | 50.0% | |
| 42.86% | 7 | 7.0 | 1,113 | 10,617 | 42.9% | 0.0% | |
| 71.43% | 7 | 6.0 | 1,187 | 12,404 | 50.0% | 100.0% | |
| 66.67% | 6 | 1.1 | 1,099 | 13,683 | 66.7% | 66.7% | |
| 50.00% | 6 | 4.2 | 980 | 14,274 | 0.0% | 50.0% | |
| 83.33% | 6 | 2.6 | 1,116 | 12,360 | 66.7% | 100.0% | |
| 50.00% | 6 | 7.2 | 1,456 | 14,141 | 100.0% | 25.0% | |
| 83.33% | 6 | 6.7 | 978 | 11,800 | 75.0% | 100.0% | |
| 50.00% | 6 | 3.8 | 1,022 | 13,025 | 100.0% | 40.0% | |
| 33.33% | 6 | 1.7 | 1,245 | 13,260 | 50.0% | 25.0% | |
| 83.33% | 6 | 6.1 | 1,398 | 13,268 | 75.0% | 100.0% | |
| 66.67% | 6 | 7.4 | 1,179 | 14,684 | 100.0% | 50.0% | |
| 50.00% | 6 | 5.8 | 1,148 | 12,202 | 66.7% | 33.3% | |
| 50.00% | 6 | 6.3 | 1,105 | 11,586 | 50.0% | 50.0% | |
| 20.00% | 5 | 1.9 | 1,157 | 15,639 | 50.0% | 0.0% | |
| 40.00% | 5 | 1.3 | 1,189 | 15,253 | 50.0% | 33.3% | |
| 60.00% | 5 | 3.7 | 1,426 | 12,666 | 33.3% | 100.0% | |
| 50.00% | 5 | 6.1 | 1,476 | 13,468 | 0.0% | 66.7% | |
| 0.00% | 5 | 5.9 | 1,437 | 15,443 | 0.0% | 0.0% | |
| 60.00% | 5 | 3.2 | 1,307 | 14,549 | 0.0% | 100.0% | |
| 20.00% | 5 | 2.5 | 1,322 | 15,760 | 0.0% | 25.0% | |
| 40.00% | 5 | 3.5 | 1,362 | 15,067 | 0.0% | 50.0% | |
| 60.00% | 5 | 7.8 | 897 | 9,918 | 33.3% | 100.0% | |
| 0.00% | 5 | 7.2 | 853 | 11,885 | 0.0% | 0.0% | |
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Karthus vs Kayn - Frequently Asked Questions
How does Karthus do against Kayn in League of Legends?
Kayn wins the Karthus vs Kayn matchup with a 70.4% win rate compared to Karthus's 29.6%, a 40.7 percentage point difference. This data is based on 54 recent ranked games in patch 26.4.
How does Karthus do against Kayn in the early game?
In the early game, Kayn has the advantage against Karthus with a 63.0% win rate versus 37.0%. Kayn players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karthus do against Kayn in the late game?
In the late game, Kayn takes over the Karthus vs Kayn matchup with a 77.8% win rate compared to 22.2%. Kayn scales better into team fights and objective contests after 25 minutes.
Who wins the Karthus vs Kayn matchup?
Kayn wins the matchup against Karthus with a 70.4% win rate in League of Legends patch 26.4. The 40.7 percentage point advantage means Kayn is significantly favored in this lane matchup based on 54 games analyzed.
What is the best Karthus build against Kayn?
The best Karthus build against Kayn includes Shadowflame, Rabadon's Deathcap, Blackfire Torch with Sorcerer's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Karthus runes against Kayn?
The best Karthus runes against Kayn use the Domination primary tree with Precision secondary. This rune setup achieves a 33.3% win rate in the Karthus vs Kayn matchup. See the full rune breakdown in the matchup comparison above.
Does Karthus counter Kayn?
No, Karthus struggles against Kayn with only a 29.6% win rate. Kayn has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Kayn's lead.
How do I play Karthus against Kayn?
When playing Karthus against Kayn, play cautiously and avoid Kayn's power spikes. Look for jungle assistance and team-dependent plays since Kayn has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.