Twisted Fate - League of Legends Champion
Win Rate
47.8%
Pick Rate
1.9%

Twisted Fatevs Vayne

FMageMarksman
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 2, 2026
MethodologyData Methodology

Twisted Fate vs Vayne is a decisive matchup in LoL patch 26.11. Twisted Fate wins with a 57.1% win rate (+14.3%) over Vayne based on 14 games. Vayne wins the early laning phase while Twisted Fate scales better into the late game. Below you'll find the best Twisted Fate build, runes, laning stats, and strategies for the Twisted Fate vs Vayne matchup.

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Twisted Fate Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Twisted Fate performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Twisted Fate - 57.1% win rate in this matchup
Twisted Fate
57.1% WR
VS
Vayne vs Twisted Fate matchup - 42.9% win rate
Vayne
42.9% WR

Who Wins the Twisted Fate vs Vayne Matchup?

Twisted Fate wins the Twisted Fate vs Vayne matchup
Winner
Twisted Fate
Matches: 14
57.1%
Win Rate
42.9%
5.8
CS / min
6.4
741
DMG / min
824
15,066
Gold / game
13,966
150
Heal / min
222
422
DMG Mitigated / min
532
1.1
CC / min
0.3
25.0%
Early Game WR
75.0%
70.0%
Late Game WR
30.0%

Twisted Fate vs Vayne Matchup Summary

The Twisted Fate vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 14 recent matches analyzed, Twisted Fate wins with a 57.1% win rate compared to Vayne's 42.9%, giving Twisted Fate a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Twisted Fate outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Twisted Fate reaches their power spikes, while Twisted Fate should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Twisted Fate leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Twisted Fate players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Twisted Fate vs Vayne Laning Phase Breakdown

Vayne wins the laning phase against Twisted Fate in League of Legends

Vayne is favored during the laning phase against Twisted Fate, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and sustain, making them the stronger laner in this matchup.

Farming
5.8Twisted Fate
6.4Vayne
Vayne edges out Twisted Fate by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 9 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
741Twisted Fate
824Vayne
Vayne heavily out-damages Twisted Fate by 84 DMG/min, dominating both short trades and all-in fights. Twisted Fate should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
15,066Twisted Fate
13,966Vayne
Twisted Fate generates a commanding 1,099 more gold per game than Vayne. This substantial economic advantage means Twisted Fate consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.1Twisted Fate
0.3Vayne
Twisted Fate provides 0.7 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Twisted Fate coordinate with their jungler and control the pace of skirmishes.
Sustain
572Twisted Fate
754Vayne
Vayne vastly out-sustains Twisted Fate, healing and mitigating 183 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Twisted Fate is forced to recall. Building grievous wounds early is essential for Twisted Fate, and focusing on burst trade patterns rather than sustained fights is critical.

Best Twisted Fate Build Against Vayne

Boots of Swiftness is the optimal boots choice against Vayne, providing the mobility and stats Twisted Fate needs most in this matchup. The top-performing core items for Twisted Fate against Vayne are Rod of Ages, Lich Bane and Rapid Firecannon. This combination gives Twisted Fate an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Twisted Fate vs Vayne matchup.

Early Game vs Late Game

Early Game
Vayne
75.0%
+50.0% advantage
Twisted Fate early game win rateTwisted Fate25.0%
Vayne early game win rateVayne75.0%
Late Game
Twisted Fate
70.0%
+40.0% advantage
Twisted Fate late game win rateTwisted Fate70.0%
Vayne late game win rateVayne30.0%

Vayne dominates the early game (first 15 minutes) with a commanding 75.0% win rate — a 50.0 percentage point lead over Twisted Fate. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Twisted Fate is far superior in the late game (25+ minutes), boasting a 70.0% win rate — 40.0 points above Vayne. Extended games heavily favor Twisted Fate, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Twisted Fate reaches their scaling breakpoints. If Twisted Fate survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Twisted Fate Runes Against Vayne

Precision rune tree - Twisted Fate primary runes vs VaynePrecision
Lethal Tempo - best Twisted Fate rune vs VayneTriumph - best Twisted Fate rune vs VayneLegend: Alacrity - best Twisted Fate rune vs VayneCoup de Grace - best Twisted Fate rune vs Vayne
Sorcery rune tree - Twisted Fate secondary runes vs VayneSorcery
Gathering Storm - best Twisted Fate rune vs VayneCelerity - best Twisted Fate rune vs Vayne
100.0% WR

Running Precision primary with Sorcery secondary allows Twisted Fate to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Twisted Fate matchup data for League of Legends patch 26.11. The table below shows Twisted Fate's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Twisted Fate build, runes, laning stats, and early vs late game analysis for that specific matchup.

Twisted Fate matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.48%1326.577612,56747.4%49.3%
52.03%1236.876913,69960.4%45.7%
50.00%1006.576212,19453.3%47.3%
45.65%925.976312,48650.0%42.9%
49.45%916.680511,95657.1%42.9%
55.06%896.277311,79450.0%59.2%
44.71%856.474811,84841.5%47.7%
48.78%826.369011,79837.2%61.5%
44.29%705.973312,40439.3%47.6%
48.53%686.370412,53940.7%53.7%
48.53%686.463011,59736.4%60.0%
48.48%666.370611,93336.1%63.3%
49.23%656.173912,40055.6%44.7%
42.19%646.286312,67837.9%45.7%
53.33%606.072111,27446.4%59.4%
55.93%596.376912,91354.5%56.8%
55.77%526.277912,49772.2%47.1%
46.00%505.869511,55438.1%51.7%
41.30%466.568912,30150.0%35.7%
40.00%456.483312,42138.1%41.7%
38.64%446.566813,22240.0%37.9%
45.45%447.071210,92650.0%38.9%
47.73%446.567812,56050.0%46.4%
37.21%436.576611,32827.8%44.0%
58.14%436.370711,50954.2%63.2%
54.76%426.175811,88452.2%57.9%
60.98%416.384813,23057.1%63.0%
42.50%406.567312,91053.3%36.0%
56.76%376.171012,78353.3%59.1%
47.22%366.278211,85950.0%45.0%
42.42%336.078312,23235.3%50.0%
66.67%336.675511,53868.8%64.7%
59.38%325.271512,47758.3%60.0%
56.67%307.074812,42460.0%53.3%
43.33%306.372612,18846.7%40.0%
28.00%255.879212,29830.8%25.0%
48.00%256.872712,94650.0%45.5%
62.50%246.593013,85475.0%56.3%
40.91%226.479113,86762.5%28.6%
52.38%216.893111,00557.1%42.9%
61.90%216.690612,91860.0%63.6%
50.00%205.966710,77963.6%33.3%
55.00%206.667810,69066.7%37.5%
30.00%206.062111,58025.0%33.3%
52.63%195.981513,12275.0%36.4%
55.56%186.788713,70457.1%54.5%
41.18%176.478512,38640.0%42.9%
17.65%175.95219,92920.0%14.3%
64.71%176.590715,241100.0%53.9%
56.25%166.674614,54271.4%44.4%
43.75%165.850812,51237.5%50.0%
33.33%156.570911,57642.9%25.0%
57.14%145.874115,06625.0%70.0%
50.00%146.068213,33450.0%50.0%
42.86%145.990212,34042.9%42.9%
50.00%146.493713,08950.0%50.0%
57.14%146.377312,65250.0%62.5%
50.00%144.267111,82250.0%50.0%
42.86%145.362510,63044.4%40.0%
35.71%146.188312,88316.7%50.0%
61.54%136.271213,03866.7%60.0%
61.54%136.564113,04683.3%42.9%
25.00%125.858112,74416.7%33.3%
41.67%126.371412,55433.3%50.0%
50.00%125.983913,43766.7%33.3%
60.00%104.851710,01257.1%66.7%
50.00%106.893511,49933.3%75.0%
70.00%106.981810,80260.0%80.0%
50.00%103.668913,40760.0%40.0%
33.33%95.268413,12333.3%33.3%
55.56%95.783114,07366.7%33.3%
44.44%96.998914,77266.7%33.3%
22.22%95.754410,92316.7%33.3%
66.67%95.788513,22075.0%60.0%
33.33%95.265010,98425.0%40.0%
66.67%94.757313,43475.0%60.0%
37.50%85.856111,91433.3%50.0%
37.50%84.263912,0220.0%60.0%
37.50%85.965210,97940.0%33.3%
12.50%85.673310,77620.0%0.0%
37.50%85.879013,26320.0%66.7%
12.50%86.054512,2720.0%20.0%
28.57%75.572610,36650.0%0.0%
71.43%72.154810,05566.7%75.0%
71.43%76.486217,828100.0%60.0%
71.43%77.172810,82583.3%0.0%
57.14%76.48939,16860.0%50.0%
57.14%76.792711,95766.7%0.0%
42.86%76.694913,20025.0%66.7%
16.67%66.860412,81750.0%0.0%
66.67%63.45018,40975.0%50.0%
66.67%66.390412,785100.0%33.3%
50.00%63.151010,83533.3%66.7%
66.67%66.478512,46966.7%66.7%
33.33%66.577912,425100.0%20.0%
16.67%66.876712,55933.3%0.0%
16.67%65.76998,9400.0%33.3%
16.67%62.582013,72733.3%0.0%
50.00%66.85359,78250.0%50.0%
50.00%66.978612,04775.0%0.0%
50.00%65.777112,67150.0%50.0%
33.33%66.666013,73350.0%25.0%
83.33%61.44836,98475.0%100.0%
16.67%61.44957,6120.0%100.0%
60.00%55.764012,9430.0%60.0%
20.00%53.45836,05620.0%0.0%
20.00%54.865311,99633.3%0.0%
20.00%52.756310,55950.0%0.0%

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Twisted Fate vs Vayne - Frequently Asked Questions

How does Twisted Fate do against Vayne in League of Legends?

Twisted Fate wins the Twisted Fate vs Vayne matchup with a 57.1% win rate compared to Vayne's 42.9%, a 14.3 percentage point difference. This data is based on 14 recent ranked games in patch 26.11.

How does Twisted Fate do against Vayne in the early game?

In the early game, Vayne has the advantage against Twisted Fate with a 75.0% win rate versus 25.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Twisted Fate do against Vayne in the late game?

In the late game, Twisted Fate takes over the Twisted Fate vs Vayne matchup with a 70.0% win rate compared to 30.0%. Twisted Fate scales better into team fights and objective contests after 25 minutes.

Who wins the Twisted Fate vs Vayne matchup?

Twisted Fate wins the matchup against Vayne with a 57.1% win rate in League of Legends patch 26.11. The 14.3 percentage point advantage means Twisted Fate is significantly favored in this lane matchup based on 14 games analyzed.

What is the best Twisted Fate build against Vayne?

The best Twisted Fate build against Vayne includes Rod of Ages, Lich Bane, Rapid Firecannon with Boots of Swiftness. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Twisted Fate runes against Vayne?

The best Twisted Fate runes against Vayne use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Twisted Fate vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Twisted Fate counter Vayne?

Yes, Twisted Fate has a favorable matchup against Vayne with a 57.1% win rate. Twisted Fate strongly counters Vayne in lane based on current patch 26.11 data.

How do I play Twisted Fate against Vayne?

When playing Twisted Fate against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Vayne. Build the recommended items and runes for this specific matchup for the best results.