Twisted Fate - League of Legends Champion
Win Rate
50.7%
Pick Rate
2.2%

Twisted Fatevs Vayne

AMageMarksman
Patch26.4
Matches846,550
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 27, 2026
MethodologyData Methodology

Twisted Fate vs Vayne is a decisive matchup in LoL patch 26.4. Twisted Fate wins with a 100.0% win rate (+100.0%) over Vayne based on 6 games. Twisted Fate holds the advantage in both the early and late game. Below you'll find the best Twisted Fate build, runes, laning stats, and strategies for the Twisted Fate vs Vayne matchup.

Twisted Fate Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Twisted Fate performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 100.0% win rateVayne(100.0%)
Twisted Fate - 100.0% win rate in this matchup
Twisted Fate
100.0% WR
VS
Vayne vs Twisted Fate matchup - 0.0% win rate
Vayne
0.0% WR

Who Wins the Twisted Fate vs Vayne Matchup?

Twisted Fate wins the Twisted Fate vs Vayne matchup
Winner
Twisted Fate
Matches: 6
100.0%
Win Rate
0.0%
6.2
CS / min
6.0
850
DMG / min
1,090
17,940
Gold / game
14,964
194
Heal / min
287
514
DMG Mitigated / min
695
1.2
CC / min
0.3
100.0%
Early Game WR
0.0%
100.0%
Late Game WR
0.0%

Twisted Fate vs Vayne Matchup Summary

The Twisted Fate vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Twisted Fate wins with a 100.0% win rate compared to Vayne's 0.0%, giving Twisted Fate a 100.0 percentage point advantage. Twisted Fate dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Twisted Fate leads by 0.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Twisted Fate players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Twisted Fate vs Vayne Laning Phase Breakdown

Twisted Fate wins the laning phase against Vayne in League of Legends

Twisted Fate is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Twisted Fate holds advantages in farming, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.2Twisted Fate
6.0Vayne
Twisted Fate and Vayne farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
850Twisted Fate
1,090Vayne
Vayne heavily out-damages Twisted Fate by 240 DMG/min, dominating both short trades and all-in fights. Twisted Fate should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
17,940Twisted Fate
14,964Vayne
Twisted Fate generates a commanding 2,976 more gold per game than Vayne. This substantial economic advantage means Twisted Fate consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vayne should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Twisted Fate
0.3Vayne
Twisted Fate brings significantly more crowd control than Vayne, with 0.9 more seconds of CC per minute. This large utility gap makes Twisted Fate far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
708Twisted Fate
982Vayne
Vayne vastly out-sustains Twisted Fate, healing and mitigating 274 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Twisted Fate is forced to recall. Building grievous wounds early is essential for Twisted Fate, and focusing on burst trade patterns rather than sustained fights is critical.

Best Twisted Fate Build Against Vayne

Spellslinger's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Twisted Fate needs most in this matchup. The top-performing core items for Twisted Fate against Vayne are Luden's Echo, Zhonya's Hourglass and Lich Bane. This combination gives Twisted Fate an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Twisted Fate vs Vayne matchup.

Early Game vs Late Game

Early Game
Twisted Fate
100.0%
+100.0% advantage
Twisted Fate early game win rateTwisted Fate100.0%
Vayne early game win rateVayne0.0%
Late Game
Twisted Fate
100.0%
+100.0% advantage
Twisted Fate late game win rateTwisted Fate100.0%
Vayne late game win rateVayne0.0%

Twisted Fate dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Twisted Fate can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Twisted Fate is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vayne. Extended games heavily favor Twisted Fate, whose kit and scaling make them a dominant force in team fights and objective control.

Twisted Fate holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Twisted Fate Runes Against Vayne

Precision rune tree - Twisted Fate primary runes vs VaynePrecision
Lethal Tempo - best Twisted Fate rune vs VayneTriumph - best Twisted Fate rune vs VayneLegend: Alacrity - best Twisted Fate rune vs VayneCut Down - best Twisted Fate rune vs Vayne
Inspiration rune tree - Twisted Fate secondary runes vs VayneInspiration
Cash Back - best Twisted Fate rune vs VayneTriple Tonic - best Twisted Fate rune vs Vayne
100.0% WR

Running Precision primary with Inspiration secondary allows Twisted Fate to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Twisted Fate matchup data for League of Legends patch 26.4. The table below shows Twisted Fate's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Twisted Fate build, runes, laning stats, and early vs late game analysis for that specific matchup.

Twisted Fate matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.09%2366.775512,81845.2%50.8%
50.54%1866.871213,17349.4%51.5%
52.63%1526.570912,57647.4%57.9%
59.72%1456.874013,23764.9%56.3%
47.37%1156.681913,31257.5%40.3%
54.63%1086.772212,21052.6%56.9%
58.88%1076.473811,90855.7%63.0%
39.80%986.769513,51341.9%38.8%
55.21%975.867512,08445.8%64.6%
47.87%956.162211,38154.2%41.3%
55.56%816.880713,09553.9%57.1%
55.84%796.276112,05054.5%57.6%
56.41%786.566112,72847.2%64.3%
45.95%756.472313,05845.5%46.3%
51.35%746.280912,88054.8%48.8%
54.93%716.369311,72356.4%53.1%
51.43%706.568412,63561.3%43.6%
52.86%706.373413,16746.7%57.5%
50.72%696.272811,95953.1%48.6%
52.24%676.368111,99840.6%62.9%
62.12%666.984112,73274.2%51.4%
46.67%606.476512,41848.3%45.2%
45.76%606.173513,36063.6%35.1%
46.55%586.372712,91344.4%48.4%
57.89%586.768912,52050.0%66.7%
58.93%576.468813,15044.4%72.4%
50.91%566.476014,07357.1%47.1%
43.40%536.674012,98737.5%48.3%
36.54%526.573912,67337.0%36.0%
54.35%477.082212,42853.3%56.3%
38.10%436.471212,65726.3%47.8%
55.00%416.268211,56655.0%55.0%
36.84%396.269110,76033.3%42.9%
59.46%376.874912,46947.4%72.2%
55.88%346.873612,53250.0%62.5%
42.42%336.368111,64140.9%45.5%
45.16%316.080412,01742.1%50.0%
55.17%297.178713,80454.5%55.6%
44.44%276.885512,21553.3%33.3%
51.85%276.981412,82950.0%53.9%
56.52%236.772113,10445.5%66.7%
40.91%226.074814,07655.6%30.8%
47.62%215.070311,54058.3%33.3%
55.00%207.490314,61858.3%50.0%
55.00%205.367611,73772.7%33.3%
60.00%205.574112,05966.7%54.5%
36.84%196.675413,07540.0%33.3%
47.37%196.380612,81357.1%41.7%
44.44%187.771611,57653.3%0.0%
33.33%186.568611,96622.2%44.4%
41.18%177.097715,12950.0%33.3%
43.75%166.898012,10112.5%75.0%
64.29%147.068312,83575.0%50.0%
78.57%145.985013,06071.4%85.7%
78.57%146.890813,78150.0%90.0%
50.00%145.982814,97975.0%40.0%
64.29%146.171612,38857.1%71.4%
28.57%147.075211,28233.3%20.0%
30.77%136.363110,28136.4%0.0%
50.00%124.656513,23560.0%42.9%
58.33%126.572512,22760.0%57.1%
58.33%126.773213,53550.0%66.7%
83.33%126.867413,11083.3%83.3%
54.55%116.176411,19540.0%66.7%
50.00%104.357612,266100.0%16.7%
50.00%101.53619,42816.7%100.0%
40.00%105.456511,84340.0%40.0%
60.00%107.176513,65640.0%80.0%
60.00%102.961010,24357.1%66.7%
66.67%96.650513,55966.7%66.7%
33.33%96.296313,11266.7%16.7%
37.50%96.665110,79933.3%50.0%
75.00%81.74529,57780.0%66.7%
62.50%84.247810,89666.7%50.0%
50.00%81.747510,73166.7%40.0%
42.86%75.786615,5190.0%60.0%
28.57%75.383611,36125.0%33.3%
28.57%75.51,01811,99933.3%25.0%
71.43%76.460111,82266.7%75.0%
42.86%71.93958,94933.3%100.0%
50.00%66.292215,92050.0%50.0%
100.00%66.285017,940100.0%100.0%
50.00%64.489915,07850.0%50.0%
66.67%67.299014,056100.0%50.0%
50.00%66.46767,75333.3%66.7%
16.67%62.559211,08050.0%0.0%
50.00%66.489313,50233.3%66.7%
83.33%67.465612,043100.0%75.0%
40.00%56.875812,18233.3%50.0%
40.00%55.01,00916,1220.0%40.0%
20.00%56.982213,9620.0%33.3%
20.00%56.382212,86033.3%0.0%
60.00%55.096514,20533.3%100.0%
60.00%56.865412,639100.0%33.3%
80.00%57.366310,96280.0%0.0%
20.00%54.068711,06825.0%0.0%
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Twisted Fate vs Vayne - Frequently Asked Questions

How does Twisted Fate do against Vayne in League of Legends?

Twisted Fate wins the Twisted Fate vs Vayne matchup with a 100.0% win rate compared to Vayne's 0.0%, a 100.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.4.

How does Twisted Fate do against Vayne in the early game?

In the early game, Twisted Fate has the advantage against Vayne with a 100.0% win rate versus 0.0%. Twisted Fate players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Twisted Fate do against Vayne in the late game?

In the late game, Twisted Fate takes over the Twisted Fate vs Vayne matchup with a 100.0% win rate compared to 0.0%. Twisted Fate scales better into team fights and objective contests after 25 minutes.

Who wins the Twisted Fate vs Vayne matchup?

Twisted Fate wins the matchup against Vayne with a 100.0% win rate in League of Legends patch 26.4. The 100.0 percentage point advantage means Twisted Fate is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Twisted Fate build against Vayne?

The best Twisted Fate build against Vayne includes Luden's Echo, Zhonya's Hourglass, Lich Bane with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Twisted Fate runes against Vayne?

The best Twisted Fate runes against Vayne use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Twisted Fate vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Twisted Fate counter Vayne?

Yes, Twisted Fate has a favorable matchup against Vayne with a 100.0% win rate. Twisted Fate strongly counters Vayne in lane based on current patch 26.4 data.

How do I play Twisted Fate against Vayne?

When playing Twisted Fate against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.