Twisted Fate - League of Legends Champion
Win Rate
48.5%
Pick Rate
1.8%

Twisted Fatevs Seraphine

FMageMarksman
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 12, 2026
MethodologyData Methodology

Twisted Fate vs Seraphine is a decisive matchup in LoL patch 26.7. Seraphine wins with a 62.5% win rate (+25.0%) over Twisted Fate based on 8 games. Seraphine wins the early laning phase while Twisted Fate scales better into the late game. Below you'll find the best Twisted Fate build, runes, laning stats, and strategies for the Twisted Fate vs Seraphine matchup.

Twisted Fate Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Twisted Fate performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 37.5% win rateSeraphine(37.5%)
Twisted Fate - 37.5% win rate in this matchup
Twisted Fate
37.5% WR
VS
Seraphine vs Twisted Fate matchup - 62.5% win rate
Seraphine
62.5% WR

Who Wins the Twisted Fate vs Seraphine Matchup?

Seraphine wins the Twisted Fate vs Seraphine matchup
Winner
Seraphine
Matches: 8
37.5%
Win Rate
62.5%
4.3
CS / min
4.1
575
DMG / min
647
11,168
Gold / game
10,851
163
Heal / min
278
447
DMG Mitigated / min
331
1.4
CC / min
1.4
0.0%
Early Game WR
100.0%
100.0%
Late Game WR
0.0%

Twisted Fate vs Seraphine Matchup Summary

The Twisted Fate vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 8 recent matches analyzed, Seraphine wins with a 62.5% win rate compared to Twisted Fate's 37.5%, giving Seraphine a 25.0 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Twisted Fate outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Twisted Fate reaches their power spikes, while Twisted Fate should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Seraphine leads by 72 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Twisted Fate players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Twisted Fate vs Seraphine Laning Phase Breakdown

Twisted Fate wins the laning phase against Seraphine in League of Legends

Twisted Fate is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Twisted Fate holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
4.3Twisted Fate
4.1Seraphine
Twisted Fate and Seraphine farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
575Twisted Fate
647Seraphine
Seraphine deals 72 more champion damage per minute than Twisted Fate. While noticeable in extended trades, this gap can be offset by Twisted Fate choosing favorable fight windows, such as engaging when Seraphine's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
11,168Twisted Fate
10,851Seraphine
Twisted Fate earns 317 more gold per game than Seraphine, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Twisted Fate slightly faster item completions.
Utility
1.4Twisted Fate
1.4Seraphine
Both Twisted Fate and Seraphine provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
610Twisted Fate
609Seraphine
Twisted Fate and Seraphine have comparable sustain profiles, with only 1 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Twisted Fate Build Against Seraphine

Boots of Swiftness is the optimal boots choice against Seraphine, providing the mobility and stats Twisted Fate needs most in this matchup. The top-performing core items for Twisted Fate against Seraphine are Dead Man's Plate, Lich Bane and Rapid Firecannon. This combination gives Twisted Fate an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Twisted Fate vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
100.0%
+100.0% advantage
Twisted Fate early game win rateTwisted Fate0.0%
Seraphine early game win rateSeraphine100.0%
Late Game
Twisted Fate
100.0%
+100.0% advantage
Twisted Fate late game win rateTwisted Fate100.0%
Seraphine late game win rateSeraphine0.0%

Seraphine dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Twisted Fate. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Twisted Fate is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Seraphine. Extended games heavily favor Twisted Fate, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Seraphine must aggressively press their early advantage and close out the game before Twisted Fate reaches their scaling breakpoints. If Twisted Fate survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Twisted Fate Runes Against Seraphine

Domination rune tree - Twisted Fate primary runes vs SeraphineDomination
Dark Harvest - best Twisted Fate rune vs SeraphineCheap Shot - best Twisted Fate rune vs SeraphineGrisly Mementos - best Twisted Fate rune vs SeraphineRelentless Hunter - best Twisted Fate rune vs Seraphine
Sorcery rune tree - Twisted Fate secondary runes vs SeraphineSorcery
Celerity - best Twisted Fate rune vs SeraphineGathering Storm - best Twisted Fate rune vs Seraphine
100.0% WR

The Domination and Sorcery rune setup gives Twisted Fate the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Twisted Fate matchup data for League of Legends patch 26.7. The table below shows Twisted Fate's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Twisted Fate build, runes, laning stats, and early vs late game analysis for that specific matchup.

Twisted Fate matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.28%1066.670512,64441.7%48.3%
48.84%866.973813,28545.5%52.4%
51.61%626.370512,16742.4%62.1%
59.32%596.473311,70665.7%50.0%
44.23%526.268713,26150.0%42.1%
52.94%516.874313,23363.0%41.7%
60.42%486.280512,05665.4%54.5%
46.81%476.276011,66750.0%43.5%
28.26%466.069112,23129.4%27.6%
58.70%466.174912,29654.5%62.5%
50.00%446.371312,30247.6%52.2%
53.49%436.864711,98861.9%45.5%
41.86%436.078613,33046.1%40.0%
51.28%396.477012,11254.5%47.1%
37.84%376.263511,31635.0%41.2%
55.88%346.372012,19346.7%63.2%
62.50%326.668811,49557.9%69.2%
34.38%326.266512,53236.4%33.3%
64.52%316.473611,61675.0%53.3%
48.39%316.284112,74140.0%56.3%
50.00%306.585513,96930.8%64.7%
37.93%296.378213,25916.7%52.9%
44.44%276.369811,83826.7%66.7%
29.63%276.467411,60929.4%30.0%
48.00%256.178512,83612.5%64.7%
52.00%256.273613,43933.3%62.5%
45.83%245.867412,76655.6%40.0%
61.90%217.278613,97160.0%63.6%
55.00%206.176812,18262.5%50.0%
55.00%206.971111,55653.9%57.1%
52.63%195.968312,37766.7%40.0%
55.56%187.470011,38258.3%50.0%
58.82%176.775512,18560.0%57.1%
58.82%177.181613,82675.0%44.4%
50.00%166.351710,10763.6%20.0%
50.00%166.266910,48466.7%28.6%
43.75%166.172812,27742.9%44.4%
20.00%156.685312,22825.0%14.3%
50.00%146.989513,63850.0%50.0%
21.43%146.062911,72740.0%11.1%
30.77%136.780512,41150.0%0.0%
30.77%135.964511,90220.0%37.5%
41.67%125.776511,62457.1%20.0%
54.55%115.471813,67860.0%50.0%
54.55%116.279714,46566.7%40.0%
50.00%106.278512,85066.7%25.0%
80.00%106.365012,125100.0%75.0%
50.00%105.87409,39750.0%50.0%
50.00%107.070513,45425.0%66.7%
44.44%95.679710,26250.0%33.3%
44.44%96.070311,02640.0%50.0%
33.33%96.05749,36740.0%25.0%
22.22%95.776112,9870.0%40.0%
55.56%95.683617,8530.0%62.5%
37.50%84.357511,1680.0%100.0%
62.50%86.373212,62450.0%75.0%
62.50%86.371214,79933.3%80.0%
0.00%86.15079,3040.0%0.0%
62.50%85.678514,49550.0%66.7%
75.00%86.885913,34775.0%75.0%
28.57%76.066514,08525.0%33.3%
85.71%75.359612,20580.0%100.0%
42.86%76.272314,8950.0%60.0%
42.86%75.562213,60533.3%50.0%
42.86%76.178812,89166.7%25.0%
50.00%66.658811,34075.0%0.0%
50.00%67.681614,41550.0%50.0%
50.00%65.460615,416100.0%40.0%
60.00%54.27889,01766.7%50.0%
100.00%56.571816,188100.0%100.0%
40.00%55.479613,27133.3%50.0%
20.00%56.461112,51633.3%0.0%
20.00%54.099211,8730.0%25.0%
80.00%53.961713,15166.7%100.0%
60.00%56.496714,86533.3%100.0%
60.00%57.098810,43033.3%100.0%
40.00%51.65349,28166.7%0.0%

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Twisted Fate vs Seraphine - Frequently Asked Questions

How does Twisted Fate do against Seraphine in League of Legends?

Seraphine wins the Twisted Fate vs Seraphine matchup with a 62.5% win rate compared to Twisted Fate's 37.5%, a 25.0 percentage point difference. This data is based on 8 recent ranked games in patch 26.7.

How does Twisted Fate do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Twisted Fate with a 100.0% win rate versus 0.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Twisted Fate do against Seraphine in the late game?

In the late game, Twisted Fate takes over the Twisted Fate vs Seraphine matchup with a 100.0% win rate compared to 0.0%. Twisted Fate scales better into team fights and objective contests after 25 minutes.

Who wins the Twisted Fate vs Seraphine matchup?

Seraphine wins the matchup against Twisted Fate with a 62.5% win rate in League of Legends patch 26.7. The 25.0 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 8 games analyzed.

What is the best Twisted Fate build against Seraphine?

The best Twisted Fate build against Seraphine includes Dead Man's Plate, Lich Bane, Rapid Firecannon with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Twisted Fate runes against Seraphine?

The best Twisted Fate runes against Seraphine use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Twisted Fate vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Twisted Fate counter Seraphine?

No, Twisted Fate struggles against Seraphine with only a 37.5% win rate. Seraphine has the advantage in this matchup. Twisted Fate players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Twisted Fate against Seraphine?

When playing Twisted Fate against Seraphine, play cautiously and avoid Seraphine's power spikes. Focus on safe farming — you outscale Seraphine in the late game. Use the matchup-specific build and runes above to optimize your chances.