Twisted Fate - League of Legends Champion
Win Rate
48.5%
Pick Rate
1.8%

Twisted Fatevs Syndra

FMageMarksman
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 12, 2026
MethodologyData Methodology

Twisted Fate vs Syndra is a decisive matchup in LoL patch 26.7. Syndra wins with a 65.6% win rate (+31.2%) over Twisted Fate based on 32 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Twisted Fate build, runes, laning stats, and strategies for the Twisted Fate vs Syndra matchup.

Twisted Fate Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Twisted Fate performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 34.4% win rateSyndra(34.4%)
Twisted Fate - 34.4% win rate in this matchup
Twisted Fate
34.4% WR
VS
Syndra vs Twisted Fate matchup - 65.6% win rate
Syndra
65.6% WR

Who Wins the Twisted Fate vs Syndra Matchup?

Syndra wins the Twisted Fate vs Syndra matchup
Winner
Syndra
Matches: 32
34.4%
Win Rate
65.6%
6.2
CS / min
7.0
665
DMG / min
1,072
12,532
Gold / game
14,111
160
Heal / min
97
441
DMG Mitigated / min
350
1.3
CC / min
1.4
36.4%
Early Game WR
63.6%
33.3%
Late Game WR
66.7%

Twisted Fate vs Syndra Matchup Summary

The Twisted Fate vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 32 recent matches analyzed, Syndra wins with a 65.6% win rate compared to Twisted Fate's 34.4%, giving Syndra a 31.2 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Twisted Fate players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Syndra leads by 407 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Twisted Fate players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Twisted Fate vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Twisted Fate in League of Legends

Syndra is favored during the laning phase against Twisted Fate, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.2Twisted Fate
7.0Syndra
Syndra edges out Twisted Fate by 0.8 CS per minute — a moderate farming advantage that adds up to roughly 12 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
665Twisted Fate
1,072Syndra
Syndra heavily out-damages Twisted Fate by 407 DMG/min, dominating both short trades and all-in fights. Twisted Fate should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
12,532Twisted Fate
14,111Syndra
Syndra generates a commanding 1,579 more gold per game than Twisted Fate. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Twisted Fate should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.3Twisted Fate
1.4Syndra
Both Twisted Fate and Syndra provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
601Twisted Fate
447Syndra
Twisted Fate vastly out-sustains Syndra, healing and mitigating 154 more damage per minute. This massive durability gap means Twisted Fate can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Twisted Fate Build Against Syndra

Crimson Lucidity is the optimal boots choice against Syndra, providing the mobility and stats Twisted Fate needs most in this matchup. The top-performing core items for Twisted Fate against Syndra are Rod of Ages, Zhonya's Hourglass and Lich Bane. This combination gives Twisted Fate an effective balance of damage, survivability, and utility for the matchup. This build has a 40.0% win rate across 5 games. While the overall matchup may be difficult, this item path gives Twisted Fate the best chance to compete against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Twisted Fate vs Syndra matchup.

Early Game vs Late Game

Early Game
Syndra
63.6%
+27.3% advantage
Twisted Fate early game win rateTwisted Fate36.4%
Syndra early game win rateSyndra63.6%
Late Game
Syndra
66.7%
+33.3% advantage
Twisted Fate late game win rateTwisted Fate33.3%
Syndra late game win rateSyndra66.7%

Syndra dominates the early game (first 15 minutes) with a commanding 63.6% win rate — a 27.3 percentage point lead over Twisted Fate. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Syndra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Twisted Fate. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Twisted Fate players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Twisted Fate Runes Against Syndra

Precision rune tree - Twisted Fate primary runes vs SyndraPrecision
Lethal Tempo - best Twisted Fate rune vs SyndraTriumph - best Twisted Fate rune vs SyndraLegend: Alacrity - best Twisted Fate rune vs SyndraCoup de Grace - best Twisted Fate rune vs Syndra
Domination rune tree - Twisted Fate secondary runes vs SyndraDomination
Sudden Impact - best Twisted Fate rune vs SyndraUltimate Hunter - best Twisted Fate rune vs Syndra
100.0% WR

The Precision and Domination rune setup gives Twisted Fate the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Twisted Fate matchup data for League of Legends patch 26.7. The table below shows Twisted Fate's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Twisted Fate build, runes, laning stats, and early vs late game analysis for that specific matchup.

Twisted Fate matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.28%1066.670512,64441.7%48.3%
48.84%866.973813,28545.5%52.4%
51.61%626.370512,16742.4%62.1%
59.32%596.473311,70665.7%50.0%
44.23%526.268713,26150.0%42.1%
52.94%516.874313,23363.0%41.7%
60.42%486.280512,05665.4%54.5%
46.81%476.276011,66750.0%43.5%
28.26%466.069112,23129.4%27.6%
58.70%466.174912,29654.5%62.5%
50.00%446.371312,30247.6%52.2%
53.49%436.864711,98861.9%45.5%
41.86%436.078613,33046.1%40.0%
51.28%396.477012,11254.5%47.1%
37.84%376.263511,31635.0%41.2%
55.88%346.372012,19346.7%63.2%
62.50%326.668811,49557.9%69.2%
34.38%326.266512,53236.4%33.3%
64.52%316.473611,61675.0%53.3%
48.39%316.284112,74140.0%56.3%
50.00%306.585513,96930.8%64.7%
37.93%296.378213,25916.7%52.9%
44.44%276.369811,83826.7%66.7%
29.63%276.467411,60929.4%30.0%
48.00%256.178512,83612.5%64.7%
52.00%256.273613,43933.3%62.5%
45.83%245.867412,76655.6%40.0%
61.90%217.278613,97160.0%63.6%
55.00%206.176812,18262.5%50.0%
55.00%206.971111,55653.9%57.1%
52.63%195.968312,37766.7%40.0%
55.56%187.470011,38258.3%50.0%
58.82%176.775512,18560.0%57.1%
58.82%177.181613,82675.0%44.4%
50.00%166.351710,10763.6%20.0%
50.00%166.266910,48466.7%28.6%
43.75%166.172812,27742.9%44.4%
20.00%156.685312,22825.0%14.3%
50.00%146.989513,63850.0%50.0%
21.43%146.062911,72740.0%11.1%
30.77%136.780512,41150.0%0.0%
30.77%135.964511,90220.0%37.5%
41.67%125.776511,62457.1%20.0%
54.55%115.471813,67860.0%50.0%
54.55%116.279714,46566.7%40.0%
50.00%106.278512,85066.7%25.0%
80.00%106.365012,125100.0%75.0%
50.00%105.87409,39750.0%50.0%
50.00%107.070513,45425.0%66.7%
44.44%95.679710,26250.0%33.3%
44.44%96.070311,02640.0%50.0%
33.33%96.05749,36740.0%25.0%
22.22%95.776112,9870.0%40.0%
55.56%95.683617,8530.0%62.5%
37.50%84.357511,1680.0%100.0%
62.50%86.373212,62450.0%75.0%
62.50%86.371214,79933.3%80.0%
0.00%86.15079,3040.0%0.0%
62.50%85.678514,49550.0%66.7%
75.00%86.885913,34775.0%75.0%
28.57%76.066514,08525.0%33.3%
85.71%75.359612,20580.0%100.0%
42.86%76.272314,8950.0%60.0%
42.86%75.562213,60533.3%50.0%
42.86%76.178812,89166.7%25.0%
50.00%66.658811,34075.0%0.0%
50.00%67.681614,41550.0%50.0%
50.00%65.460615,416100.0%40.0%
60.00%54.27889,01766.7%50.0%
100.00%56.571816,188100.0%100.0%
40.00%55.479613,27133.3%50.0%
20.00%56.461112,51633.3%0.0%
20.00%54.099211,8730.0%25.0%
80.00%53.961713,15166.7%100.0%
60.00%56.496714,86533.3%100.0%
60.00%57.098810,43033.3%100.0%
40.00%51.65349,28166.7%0.0%

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Twisted Fate vs Syndra - Frequently Asked Questions

How does Twisted Fate do against Syndra in League of Legends?

Syndra wins the Twisted Fate vs Syndra matchup with a 65.6% win rate compared to Twisted Fate's 34.4%, a 31.2 percentage point difference. This data is based on 32 recent ranked games in patch 26.7.

How does Twisted Fate do against Syndra in the early game?

In the early game, Syndra has the advantage against Twisted Fate with a 63.6% win rate versus 36.4%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Twisted Fate do against Syndra in the late game?

In the late game, Syndra takes over the Twisted Fate vs Syndra matchup with a 66.7% win rate compared to 33.3%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Twisted Fate vs Syndra matchup?

Syndra wins the matchup against Twisted Fate with a 65.6% win rate in League of Legends patch 26.7. The 31.2 percentage point advantage means Syndra is significantly favored in this lane matchup based on 32 games analyzed.

What is the best Twisted Fate build against Syndra?

The best Twisted Fate build against Syndra includes Rod of Ages, Zhonya's Hourglass, Lich Bane with Crimson Lucidity. This build achieves a 40.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Twisted Fate runes against Syndra?

The best Twisted Fate runes against Syndra use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Twisted Fate vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Twisted Fate counter Syndra?

No, Twisted Fate struggles against Syndra with only a 34.4% win rate. Syndra has the advantage in this matchup. Twisted Fate players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Twisted Fate against Syndra?

When playing Twisted Fate against Syndra, play cautiously and avoid Syndra's power spikes. Look for jungle assistance and team-dependent plays since Syndra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.