Twisted Fate - League of Legends Champion
Win Rate
47.1%
Pick Rate
2.0%

Twisted Fatevs Cassiopeia

FMageMarksman
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Twisted Fate vs Cassiopeia is a decisive matchup in LoL patch 26.11. Cassiopeia wins with a 58.8% win rate (+17.6%) over Twisted Fate based on 17 games. Cassiopeia holds the advantage in both the early and late game. Below you'll find the best Twisted Fate build, runes, laning stats, and strategies for the Twisted Fate vs Cassiopeia matchup.

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Twisted Fate Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Twisted Fate performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Twisted Fate - 41.2% win rate in this matchup
Twisted Fate
41.2% WR
VS
Cassiopeia vs Twisted Fate matchup - 58.8% win rate
Cassiopeia
58.8% WR

Who Wins the Twisted Fate vs Cassiopeia Matchup?

Cassiopeia wins the Twisted Fate vs Cassiopeia matchup
Winner
Cassiopeia
Matches: 17
41.2%
Win Rate
58.8%
6.4
CS / min
6.8
785
DMG / min
858
12,386
Gold / game
11,943
156
Heal / min
228
505
DMG Mitigated / min
596
1.3
CC / min
1.3
40.0%
Early Game WR
60.0%
42.9%
Late Game WR
57.1%

Twisted Fate vs Cassiopeia Matchup Summary

The Twisted Fate vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 17 recent matches analyzed, Cassiopeia wins with a 58.8% win rate compared to Twisted Fate's 41.2%, giving Cassiopeia a 17.6 percentage point advantage. Cassiopeia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Twisted Fate players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 163 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia has a strong advantage in this matchup. Twisted Fate players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Cassiopeia overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Twisted Fate vs Cassiopeia Laning Phase Breakdown

Cassiopeia wins the laning phase against Twisted Fate in League of Legends

Cassiopeia is favored during the laning phase against Twisted Fate, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage and sustain, making them the stronger laner in this matchup.

Farming
6.4Twisted Fate
6.8Cassiopeia
Cassiopeia edges out Twisted Fate by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Cassiopeia.
Damage
785Twisted Fate
858Cassiopeia
Cassiopeia deals 73 more champion damage per minute than Twisted Fate. While noticeable in extended trades, this gap can be offset by Twisted Fate choosing favorable fight windows, such as engaging when Cassiopeia's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
12,386Twisted Fate
11,943Cassiopeia
Twisted Fate earns 443 more gold per game than Cassiopeia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Twisted Fate slightly faster item completions.
Utility
1.3Twisted Fate
1.3Cassiopeia
Both Twisted Fate and Cassiopeia provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
661Twisted Fate
824Cassiopeia
Cassiopeia vastly out-sustains Twisted Fate, healing and mitigating 163 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Twisted Fate is forced to recall. Building grievous wounds early is essential for Twisted Fate, and focusing on burst trade patterns rather than sustained fights is critical.

Best Twisted Fate Build Against Cassiopeia

Swiftmarch is the optimal boots choice against Cassiopeia, providing the mobility and stats Twisted Fate needs most in this matchup. The top-performing core items for Twisted Fate against Cassiopeia are Rod of Ages, Lich Bane and Rapid Firecannon. This combination gives Twisted Fate an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Twisted Fate vs Cassiopeia matchup.

Early Game vs Late Game

Early Game
Cassiopeia
60.0%
+20.0% advantage
Twisted Fate early game win rateTwisted Fate40.0%
Cassiopeia early game win rateCassiopeia60.0%
Late Game
Cassiopeia
57.1%
+14.3% advantage
Twisted Fate late game win rateTwisted Fate42.9%
Cassiopeia late game win rateCassiopeia57.1%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Twisted Fate. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Twisted Fate. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

Cassiopeia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Twisted Fate players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Twisted Fate Runes Against Cassiopeia

Inspiration rune tree - Twisted Fate primary runes vs CassiopeiaInspiration
Unsealed Spellbook - best Twisted Fate rune vs CassiopeiaCash Back - best Twisted Fate rune vs CassiopeiaTriple Tonic - best Twisted Fate rune vs CassiopeiaJack Of All Trades - best Twisted Fate rune vs Cassiopeia
Resolve rune tree - Twisted Fate secondary runes vs CassiopeiaResolve
Bone Plating - best Twisted Fate rune vs CassiopeiaOvergrowth - best Twisted Fate rune vs Cassiopeia
100.0% WR

The Inspiration and Resolve rune setup gives Twisted Fate the best tools to compete against Cassiopeia in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Twisted Fate matchup data for League of Legends patch 26.11. The table below shows Twisted Fate's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Twisted Fate build, runes, laning stats, and early vs late game analysis for that specific matchup.

Twisted Fate matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.48%1326.577612,56747.4%49.3%
52.03%1236.876913,69960.4%45.7%
50.00%1006.576212,19453.3%47.3%
45.65%925.976312,48650.0%42.9%
49.45%916.680511,95657.1%42.9%
55.06%896.277311,79450.0%59.2%
44.71%856.474811,84841.5%47.7%
48.78%826.369011,79837.2%61.5%
44.29%705.973312,40439.3%47.6%
48.53%686.370412,53940.7%53.7%
48.53%686.463011,59736.4%60.0%
48.48%666.370611,93336.1%63.3%
49.23%656.173912,40055.6%44.7%
42.19%646.286312,67837.9%45.7%
53.33%606.072111,27446.4%59.4%
55.93%596.376912,91354.5%56.8%
55.77%526.277912,49772.2%47.1%
46.00%505.869511,55438.1%51.7%
41.30%466.568912,30150.0%35.7%
40.00%456.483312,42138.1%41.7%
38.64%446.566813,22240.0%37.9%
45.45%447.071210,92650.0%38.9%
47.73%446.567812,56050.0%46.4%
37.21%436.576611,32827.8%44.0%
58.14%436.370711,50954.2%63.2%
54.76%426.175811,88452.2%57.9%
60.98%416.384813,23057.1%63.0%
42.50%406.567312,91053.3%36.0%
56.76%376.171012,78353.3%59.1%
47.22%366.278211,85950.0%45.0%
42.42%336.078312,23235.3%50.0%
66.67%336.675511,53868.8%64.7%
59.38%325.271512,47758.3%60.0%
56.67%307.074812,42460.0%53.3%
43.33%306.372612,18846.7%40.0%
28.00%255.879212,29830.8%25.0%
48.00%256.872712,94650.0%45.5%
62.50%246.593013,85475.0%56.3%
40.91%226.479113,86762.5%28.6%
52.38%216.893111,00557.1%42.9%
61.90%216.690612,91860.0%63.6%
50.00%205.966710,77963.6%33.3%
55.00%206.667810,69066.7%37.5%
30.00%206.062111,58025.0%33.3%
52.63%195.981513,12275.0%36.4%
55.56%186.788713,70457.1%54.5%
41.18%176.478512,38640.0%42.9%
17.65%175.95219,92920.0%14.3%
64.71%176.590715,241100.0%53.9%
56.25%166.674614,54271.4%44.4%
43.75%165.850812,51237.5%50.0%
33.33%156.570911,57642.9%25.0%
57.14%145.874115,06625.0%70.0%
50.00%146.068213,33450.0%50.0%
42.86%145.990212,34042.9%42.9%
50.00%146.493713,08950.0%50.0%
57.14%146.377312,65250.0%62.5%
50.00%144.267111,82250.0%50.0%
42.86%145.362510,63044.4%40.0%
35.71%146.188312,88316.7%50.0%
61.54%136.271213,03866.7%60.0%
61.54%136.564113,04683.3%42.9%
25.00%125.858112,74416.7%33.3%
41.67%126.371412,55433.3%50.0%
50.00%125.983913,43766.7%33.3%
60.00%104.851710,01257.1%66.7%
50.00%106.893511,49933.3%75.0%
70.00%106.981810,80260.0%80.0%
50.00%103.668913,40760.0%40.0%
33.33%95.268413,12333.3%33.3%
55.56%95.783114,07366.7%33.3%
44.44%96.998914,77266.7%33.3%
22.22%95.754410,92316.7%33.3%
66.67%95.788513,22075.0%60.0%
33.33%95.265010,98425.0%40.0%
66.67%94.757313,43475.0%60.0%
37.50%85.856111,91433.3%50.0%
37.50%84.263912,0220.0%60.0%
37.50%85.965210,97940.0%33.3%
12.50%85.673310,77620.0%0.0%
37.50%85.879013,26320.0%66.7%
12.50%86.054512,2720.0%20.0%
28.57%75.572610,36650.0%0.0%
71.43%72.154810,05566.7%75.0%
71.43%76.486217,828100.0%60.0%
71.43%77.172810,82583.3%0.0%
57.14%76.48939,16860.0%50.0%
57.14%76.792711,95766.7%0.0%
42.86%76.694913,20025.0%66.7%
16.67%66.860412,81750.0%0.0%
66.67%63.45018,40975.0%50.0%
66.67%66.390412,785100.0%33.3%
50.00%63.151010,83533.3%66.7%
66.67%66.478512,46966.7%66.7%
33.33%66.577912,425100.0%20.0%
16.67%66.876712,55933.3%0.0%
16.67%65.76998,9400.0%33.3%
16.67%62.582013,72733.3%0.0%
50.00%66.85359,78250.0%50.0%
50.00%66.978612,04775.0%0.0%
50.00%65.777112,67150.0%50.0%
33.33%66.666013,73350.0%25.0%
83.33%61.44836,98475.0%100.0%
16.67%61.44957,6120.0%100.0%
60.00%55.764012,9430.0%60.0%
20.00%53.45836,05620.0%0.0%
20.00%54.865311,99633.3%0.0%
20.00%52.756310,55950.0%0.0%

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Twisted Fate vs Cassiopeia - Frequently Asked Questions

How does Twisted Fate do against Cassiopeia in League of Legends?

Cassiopeia wins the Twisted Fate vs Cassiopeia matchup with a 58.8% win rate compared to Twisted Fate's 41.2%, a 17.6 percentage point difference. This data is based on 17 recent ranked games in patch 26.11.

How does Twisted Fate do against Cassiopeia in the early game?

In the early game, Cassiopeia has the advantage against Twisted Fate with a 60.0% win rate versus 40.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Twisted Fate do against Cassiopeia in the late game?

In the late game, Cassiopeia takes over the Twisted Fate vs Cassiopeia matchup with a 57.1% win rate compared to 42.9%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Twisted Fate vs Cassiopeia matchup?

Cassiopeia wins the matchup against Twisted Fate with a 58.8% win rate in League of Legends patch 26.11. The 17.6 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 17 games analyzed.

What is the best Twisted Fate build against Cassiopeia?

The best Twisted Fate build against Cassiopeia includes Rod of Ages, Lich Bane, Rapid Firecannon with Swiftmarch. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Twisted Fate runes against Cassiopeia?

The best Twisted Fate runes against Cassiopeia use the Inspiration primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Twisted Fate vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.

Does Twisted Fate counter Cassiopeia?

No, Twisted Fate struggles against Cassiopeia with only a 41.2% win rate. Cassiopeia has the advantage in this matchup. Twisted Fate players should focus on safe farming and avoiding extended trades to minimize Cassiopeia's lead.

How do I play Twisted Fate against Cassiopeia?

When playing Twisted Fate against Cassiopeia, play cautiously and avoid Cassiopeia's power spikes. Look for jungle assistance and team-dependent plays since Cassiopeia has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.