Vayne - League of Legends Champion
Win Rate
49.5%
Pick Rate
5.3%

Vaynevs Garen

DMarksmanAssassin
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 25, 2026
MethodologyData Methodology

Vayne vs Garen is a decisive matchup in LoL patch 26.7. Vayne wins with a 58.4% win rate (+16.8%) over Garen based on 149 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Garen matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Garen - 58.4% win rateGaren(58.4%)
Vayne - 58.4% win rate in this matchup
Vayne
58.4% WR
VS
Garen vs Vayne matchup - 41.6% win rate
Garen
41.6% WR

Who Wins the Vayne vs Garen Matchup?

Vayne wins the Vayne vs Garen matchup
Winner
Vayne
Matches: 149
58.4%
Win Rate
41.6%
6.6
CS / min
6.4
953
DMG / min
639
12,700
Gold / game
12,286
261
Heal / min
98
517
DMG Mitigated / min
1,385
0.3
CC / min
0.9
51.6%
Early Game WR
48.4%
63.5%
Late Game WR
36.5%

Vayne vs Garen Matchup Summary

The Vayne vs Garen matchup is a decisive matchup in League of Legends ranked play. Based on 149 recent matches analyzed, Vayne wins with a 58.4% win rate compared to Garen's 41.6%, giving Vayne a 16.8 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Garen players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Garen leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Garen and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Garen away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Garen Laning Phase Breakdown

Vayne wins the laning phase against Garen in League of Legends

Vayne is favored during the laning phase against Garen, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.6Vayne
6.4Garen
Vayne and Garen farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
953Vayne
639Garen
Vayne heavily out-damages Garen by 314 DMG/min, dominating both short trades and all-in fights. Garen should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
12,700Vayne
12,286Garen
Vayne earns 414 more gold per game than Garen, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.3Vayne
0.9Garen
Garen provides 0.6 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Garen coordinate with their jungler and control the pace of skirmishes.
Sustain
778Vayne
1,483Garen
Garen vastly out-sustains Vayne, healing and mitigating 704 more damage per minute. This massive durability gap means Garen can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Garen

Berserker's Greaves is the optimal boots choice against Garen, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Garen are Essence Reaver, Experimental Hexplate and Infinity Edge. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 3 games — well above average and making it the top item path against Garen. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Garen matchup.

Early Game vs Late Game

Early Game
Vayne
51.6%
+3.1% advantage
Vayne early game win rateVayne51.6%
Garen early game win rateGaren48.4%
Late Game
Vayne
63.5%
+27.1% advantage
Vayne late game win rateVayne63.5%
Garen late game win rateGaren36.5%

During the early laning phase (first 15 minutes), Vayne has a meaningful 51.6% win rate, outperforming Garen by 3.1 percentage points. Vayne players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Vayne is far superior in the late game (25+ minutes), boasting a 63.5% win rate — 27.1 points above Garen. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Garen players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Garen

Precision rune tree - Vayne primary runes vs GarenPrecision
Press the Attack - best Vayne rune vs GarenTriumph - best Vayne rune vs GarenLegend: Alacrity - best Vayne rune vs GarenCoup de Grace - best Vayne rune vs Garen
Resolve rune tree - Vayne secondary runes vs GarenResolve
Conditioning - best Vayne rune vs GarenOvergrowth - best Vayne rune vs Garen
72.2% WR

Running Precision primary with Resolve secondary allows Vayne to press their advantage against Garen, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.02%3576.081713,23145.3%52.0%
52.47%3246.289813,59649.3%55.2%
48.09%3146.283212,81944.0%52.7%
49.01%3025.982512,93747.5%50.3%
52.94%2726.083913,07152.8%53.1%
45.37%2276.496014,25446.9%44.2%
50.00%2226.493713,71750.0%50.0%
52.71%2036.585613,74148.9%56.0%
52.32%1516.582813,28755.4%49.4%
58.39%1496.695312,70051.6%63.5%
51.30%1155.881313,71761.5%42.9%
47.71%1096.088213,23938.2%57.4%
55.67%976.488012,62559.6%51.1%
51.55%976.380612,73552.5%50.0%
50.00%945.983213,59546.7%53.1%
36.36%886.279012,98330.0%41.7%
47.44%786.692813,28446.3%48.6%
61.33%756.692412,10266.7%55.6%
55.56%726.185813,24745.2%63.4%
57.35%686.085313,57456.0%58.1%
36.76%686.288112,39436.7%36.8%
52.54%596.383712,51848.5%57.7%
42.37%596.287012,82834.4%51.9%
38.60%575.760511,22540.0%37.0%
37.50%565.560110,77030.4%42.4%
43.40%536.21,04512,46744.4%42.3%
44.00%506.188613,06147.8%40.7%
53.06%496.11,21413,80450.0%55.2%
65.91%446.186913,29266.7%65.4%
56.82%445.692114,04761.1%53.9%
43.18%445.799611,54831.3%50.0%
50.00%406.384813,58435.3%60.9%
55.00%405.989314,58823.1%70.4%
57.50%406.395114,24860.0%56.7%
48.72%396.595213,49157.9%40.0%
57.89%386.01,02912,41355.0%61.1%
42.11%386.192313,74144.4%40.0%
54.05%377.092811,69252.4%56.3%
40.54%375.880412,22541.2%40.0%
40.00%355.71,14111,80838.9%41.2%
55.88%346.585611,12557.9%53.3%
50.00%326.098613,59966.7%43.5%
66.67%306.289612,54050.0%81.3%
56.67%306.298113,89653.9%58.8%
48.28%296.785812,18028.6%66.7%
55.17%296.31,02413,69462.5%46.1%
51.85%275.798412,39145.5%56.3%
61.54%266.185111,71961.5%61.5%
64.00%256.080811,77055.6%68.8%
44.00%256.892712,26342.9%45.5%
33.33%246.483511,60541.7%25.0%
56.52%235.592112,42462.5%53.3%
43.48%236.383712,92160.0%30.8%
40.91%226.678811,10141.7%40.0%
52.38%215.992313,47740.0%63.6%
60.00%205.290914,35220.0%73.3%
47.37%196.91,00811,89263.6%25.0%
50.00%186.273213,04560.0%37.5%
50.00%186.21,05312,78455.6%44.4%
44.44%186.483711,79542.9%45.5%
50.00%185.875412,37328.6%63.6%
76.47%176.91,02114,29680.0%75.0%
29.41%176.982911,89737.5%22.2%
41.18%176.086215,19160.0%33.3%
43.75%166.083811,77362.5%25.0%
56.25%166.690711,52757.1%55.6%
37.50%165.465913,20816.7%50.0%
68.75%166.793713,92583.3%60.0%
53.33%155.968611,41937.5%71.4%
73.33%156.485112,62177.8%66.7%
50.00%145.785111,11416.7%75.0%
42.86%144.364512,05114.3%71.4%
53.85%133.388514,16275.0%44.4%
53.85%135.71,05513,76250.0%55.6%
58.33%125.656210,02757.1%60.0%
25.00%124.586213,08325.0%25.0%
50.00%126.378413,32833.3%66.7%
27.27%116.277113,46233.3%25.0%
63.64%116.387415,82666.7%62.5%
36.36%116.665110,70650.0%20.0%
45.45%115.591912,62950.0%40.0%
72.73%116.474510,85071.4%75.0%
45.45%116.01,06414,50840.0%50.0%
70.00%106.699613,49075.0%66.7%
40.00%106.887613,21633.3%50.0%
55.56%96.393712,28633.3%100.0%
44.44%96.21,07715,702100.0%28.6%
33.33%96.877411,06920.0%50.0%
25.00%85.569310,37825.0%25.0%
50.00%85.99738,78533.3%100.0%
37.50%81.983414,72733.3%40.0%
42.86%75.690112,809100.0%20.0%
0.00%76.655810,7000.0%0.0%
42.86%74.665114,53850.0%40.0%
71.43%76.168213,12675.0%66.7%
57.14%75.588812,31625.0%100.0%
57.14%75.489512,10050.0%66.7%
42.86%74.077311,64333.3%50.0%
57.14%72.51,31315,57625.0%100.0%
33.33%64.65709,10525.0%50.0%
66.67%65.91,08915,49350.0%75.0%
50.00%65.776213,18250.0%50.0%
50.00%61.989114,832100.0%40.0%
16.67%65.384410,4420.0%33.3%
0.00%65.979510,7240.0%0.0%
83.33%66.196311,361100.0%50.0%
50.00%66.380413,574100.0%40.0%
40.00%54.793914,778100.0%0.0%
60.00%51.71,19517,6480.0%75.0%
20.00%51.56919,37833.3%0.0%
60.00%55.31,10015,380100.0%50.0%
20.00%56.891512,5530.0%33.3%
40.00%56.51,02117,6030.0%40.0%

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Vayne vs Garen - Frequently Asked Questions

How does Vayne do against Garen in League of Legends?

Vayne wins the Vayne vs Garen matchup with a 58.4% win rate compared to Garen's 41.6%, a 16.8 percentage point difference. This data is based on 149 recent ranked games in patch 26.7.

How does Vayne do against Garen in the early game?

In the early game, Vayne has the advantage against Garen with a 51.6% win rate versus 48.4%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Garen in the late game?

In the late game, Vayne takes over the Vayne vs Garen matchup with a 63.5% win rate compared to 36.5%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Garen matchup?

Vayne wins the matchup against Garen with a 58.4% win rate in League of Legends patch 26.7. The 16.8 percentage point advantage means Vayne is significantly favored in this lane matchup based on 149 games analyzed.

What is the best Vayne build against Garen?

The best Vayne build against Garen includes Essence Reaver, Experimental Hexplate, Infinity Edge with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Garen?

The best Vayne runes against Garen use the Precision primary tree with Resolve secondary. This rune setup achieves a 72.2% win rate in the Vayne vs Garen matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Garen?

Yes, Vayne has a favorable matchup against Garen with a 58.4% win rate. Vayne strongly counters Garen in lane based on current patch 26.7 data.

How do I play Vayne against Garen?

When playing Vayne against Garen, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.