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Vayne Runes

The top Vayne runes in LoL patch 25.23 are Press the Attack, Triumph, Legend: Alacrity, Coup de Grace for Vayne's primary runes. Vayne's runes in his secondary tree best utilizes Celerity and Scorch. These Vayne rune choices provide the best Vayne rune build for ranked.

  • Vayne passive ability - Night Hunter - League of Legends
    Night Hunter

    Night Hunter

    Vayne ruthlessly hunts evil-doers, gaining Move Speed when moving toward nearby enemy champions.

  • Vayne Q ability - Tumble - League of Legends
    Tumble

    Tumble

    Vayne tumbles, maneuvering to carefully place her next shot. Her next attack deals bonus damage.

    Cost:
    • 30
    Cooldown:
    • 6/
    • 5/
    • 4/
    • 3/
    • 2
    Range:
    • 300
  • Vayne W ability - Silver Bolts - League of Legends
    Silver Bolts

    Silver Bolts

    Vayne tips her bolts with a rare metal, toxic to evil things. The third consecutive attack or ability against the same target deals a percentage of the target's max health as bonus true damage.

    Cost:
    • 0
    Cooldown:
    • 0
    Range:
    • 750
  • Vayne E ability - Condemn - League of Legends
    Condemn

    Condemn

    Vayne draws a heavy crossbow from her back, and fires a huge bolt at her target, knocking them back and dealing damage. If they collide with terrain, they are impaled, dealing bonus damage and stunning them.

    Cost:
    • 90
    Cooldown:
    • 20/
    • 18/
    • 16/
    • 14/
    • 12
    Range:
    • 550
  • Vayne R ultimate ability - Final Hour - League of Legends
    Final Hour

    Final Hour

    Readying herself for an epic confrontation, Vayne gains increased Attack Damage, Invisibility during Tumble, reduced Tumble cooldown, and more bonus Move Speed from Night Hunter

    Cost:
    • 80
    Cooldown:
    • 100/
    • 85/
    • 70
    Range:
    • 1
Classes:
  • Marksman,
  • Assassin
50.57%Win Rate
Vayne B tier

Vayne performs best with Press the Attack as the keystone rune. The optimal primary runes for Vayne include Press the Attack, Triumph, Legend: Alacrity. This rune setup achieves a 1.00% win rate across 1 Vayne games.

This alternative Vayne rune build uses Press the Attack as the keystone. This setup provides a different playstyle for Vayne and achieves a 1.00% win rate. Consider this rune page when facing specific matchups or team compositions.

Vayne Runes - Frequently Asked Questions

What are the best Vayne runes?

The best Vayne runes in patch 25.23 are Press the Attack, Triumph, Legend: Alacrity, and Coup de Grace for the primary tree, and Celerity and Scorch for the secondary tree. These runes provide optimal performance for Vayne.

What keystone should I use on Vayne?

Press the Attack is the best keystone rune for Vayne. This keystone synergizes well with Vayne's abilities and provides maximum value in most matchups.

What are Vayne's secondary runes?

Vayne's best secondary runes are Celerity and Scorch. These secondary runes complement Vayne's primary rune choices and enhance overall effectiveness.

Can I use different rune setups on Vayne?

Yes, Vayne can utilize different rune setups depending on matchup and playstyle. While Press the Attack is most popular, alternative keystones may work better in specific situations.