VayneRunes
Best Vayne runes for LoL Patch 26.11 - Lethal Tempo from the Precision tree with Inspiration secondary (93.8% WR, 0.2% pick rate). Vayne's optimal primary runes are Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace. Secondary tree: Cash Back, Triple Tonic.
Primary Tree
Precision
Lethal TempoAttacking an enemy champion grants you [6% Melee || 4% Ranged] Attack Speed for 6 seconds, up to 6. At max stacks, deal [9 - 30 Melee || 6 - 24 Ranged]
TriumphTakedowns restore 5% of your missing health, 2.5% of your max health, and grant an additional 20 gold.
'The most dangerous game brings the greatest glory.'
—Noxian Reckoner
Legend: AlacrityGain 3% attack speed plus an additional 1.5% for every Legend stack (
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Coup de GraceDeal 8% more damage to champions who have less than 40% health.
Cash BackGet 7.5% Gold back when you purchase Legendary Items.
Triple TonicUpon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Primary Tree
Precision
Press the AttackHitting an enemy champion with 3 consecutive basic attacks deals 40 - 160 bonus
TriumphTakedowns restore 5% of your missing health, 2.5% of your max health, and grant an additional 20 gold.
'The most dangerous game brings the greatest glory.'
—Noxian Reckoner
Legend: AlacrityGain 3% attack speed plus an additional 1.5% for every Legend stack (
Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.
Cut DownDeal 8% more damage to champions who have more than 60% health.
ConditioningAfter 12 min gain +8 Armor and +8 Magic Resist and increase your Armor and Magic Resist by 3%.
OvergrowthAbsorb life essence from monsters or enemy minions that die near you, permanently gaining 3 maximum health for every 8.
When you've absorbed 120 monsters or enemy minions, gain an additional 3.5% maximum health.
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Vayne Runes - Frequently Asked Questions
What are the best Vayne runes in patch 26.11?
The best Vayne runes in patch 26.11 use the Precision tree with Lethal Tempo, Triumph, Legend: Alacrity, and Coup de Grace, and the Inspiration tree with Cash Back and Triple Tonic. This rune setup achieves a 93.8% win rate with a 0.2% pick rate.
What is the win rate for Vayne's best rune page?
Vayne's best rune page has a 93.8% win rate in patch 26.11, which is +43.3% compared to Vayne's average win rate. This rune setup has a 0.2% pick rate among Vayne players.
What keystone should I use on Vayne?
Lethal Tempo from the Precision tree is the best keystone rune for Vayne in patch 26.11. This keystone synergizes well with Vayne's kit and provides a 93.8% win rate.
What is Vayne's primary rune tree?
Vayne's primary rune tree is Precision. The optimal Precision runes for Vayne are Lethal Tempo, Triumph, Legend: Alacrity, and Coup de Grace, with Lethal Tempo being the keystone of choice.
What is Vayne's secondary rune tree?
Vayne's best secondary rune tree is Inspiration. The recommended Inspiration runes are Cash Back and Triple Tonic, which complement Vayne's Precision primary tree.
What are alternative rune setups for Vayne?
An alternative Vayne rune setup uses Press the Attack from the Precision tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Vayne's runes?
Vayne's top rune page has a 0.2% pick rate in patch 26.11. This indicates that 0.2% of Vayne players use the Lethal Tempo setup with Precision and Inspiration trees.