
Vaynevs Samira
Vayne vs Samira is a very close matchup in LoL patch 26.10. Samira wins with a 50.8% win rate (+1.6%) over Vayne based on 189 games. Samira wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Samira matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Samira Matchup?

Vayne vs Samira Matchup Summary
The Vayne vs Samira matchup is a very close matchup in League of Legends ranked play. Based on 189 recent matches analyzed, Samira wins with a 50.8% win rate compared to Vayne's 49.2%, giving Samira a 1.6 percentage point advantage. Game phase dynamics play a critical role here: Samira controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Samira needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Samira is slightly favored, Vayne can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Samira's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Samira Laning Phase Breakdown
Samira is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Samira holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.
Early Game vs Late Game
During the early laning phase (first 15 minutes), Samira has a meaningful 51.6% win rate, outperforming Vayne by 3.2 percentage points. Samira players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.
Late game (25+ minutes) is equally balanced, with Vayne at 50.0% win rate — only 0.0 points ahead of Samira. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
The power dynamics shift as the game progresses — Samira has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Vayne Runes Against Samira
The Precision primary with Resolve secondary combination helps Vayne maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Samira.
Vayne matchup data for League of Legends patch 26.10. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 44.98% | 856 | 6.1 | 880 | 13,322 | 45.6% | 44.5% | |
| 47.13% | 628 | 6.0 | 801 | 13,007 | 45.1% | 48.6% | |
| 46.70% | 621 | 6.0 | 785 | 12,961 | 46.1% | 47.1% | |
| 50.57% | 530 | 6.3 | 849 | 12,932 | 50.4% | 50.7% | |
| 50.76% | 524 | 6.1 | 853 | 13,573 | 46.8% | 53.3% | |
| 47.62% | 483 | 5.7 | 774 | 12,899 | 47.3% | 47.9% | |
| 54.67% | 428 | 6.3 | 888 | 13,110 | 50.0% | 58.9% | |
| 56.75% | 289 | 6.3 | 918 | 13,741 | 54.1% | 59.0% | |
| 52.53% | 217 | 5.9 | 830 | 13,245 | 52.6% | 52.5% | |
| 47.64% | 212 | 6.0 | 797 | 12,592 | 48.5% | 46.8% | |
| 50.25% | 201 | 6.1 | 800 | 12,898 | 45.0% | 54.5% | |
| 59.07% | 193 | 6.4 | 1,016 | 13,025 | 59.1% | 59.1% | |
| 49.21% | 189 | 5.9 | 829 | 12,620 | 48.4% | 50.0% | |
| 57.65% | 170 | 6.2 | 842 | 13,378 | 53.2% | 61.5% | |
| 50.30% | 169 | 5.8 | 808 | 12,793 | 52.6% | 48.4% | |
| 46.01% | 163 | 5.7 | 611 | 11,634 | 40.3% | 49.5% | |
| 50.63% | 158 | 6.0 | 790 | 12,716 | 39.4% | 58.7% | |
| 53.19% | 141 | 6.0 | 903 | 11,554 | 47.4% | 57.1% | |
| 48.23% | 141 | 6.1 | 853 | 13,844 | 56.6% | 43.2% | |
| 48.51% | 134 | 6.2 | 889 | 11,723 | 45.5% | 51.5% | |
| 50.40% | 125 | 6.3 | 813 | 13,600 | 49.1% | 51.4% | |
| 48.36% | 122 | 5.9 | 956 | 12,229 | 52.1% | 46.0% | |
| 47.93% | 121 | 6.5 | 825 | 12,876 | 45.2% | 50.9% | |
| 44.92% | 118 | 6.2 | 940 | 13,191 | 35.9% | 52.3% | |
| 34.21% | 114 | 5.5 | 586 | 10,060 | 31.4% | 36.5% | |
| 58.18% | 110 | 6.0 | 849 | 12,682 | 52.1% | 62.9% | |
| 57.01% | 107 | 6.3 | 873 | 13,730 | 56.8% | 57.1% | |
| 41.12% | 107 | 6.2 | 875 | 13,699 | 35.6% | 45.2% | |
| 52.17% | 92 | 6.4 | 1,150 | 13,161 | 50.0% | 53.5% | |
| 48.86% | 88 | 6.6 | 1,321 | 12,552 | 45.5% | 50.9% | |
| 55.95% | 84 | 6.0 | 985 | 12,419 | 50.0% | 60.4% | |
| 46.99% | 83 | 6.1 | 798 | 11,189 | 28.9% | 62.2% | |
| 48.10% | 79 | 6.3 | 953 | 12,434 | 42.4% | 52.2% | |
| 43.04% | 79 | 6.0 | 952 | 11,620 | 29.7% | 54.8% | |
| 50.67% | 75 | 5.9 | 922 | 12,382 | 56.1% | 44.1% | |
| 51.35% | 74 | 6.3 | 976 | 11,776 | 61.8% | 42.5% | |
| 50.00% | 72 | 6.0 | 1,069 | 11,819 | 57.1% | 43.2% | |
| 53.52% | 71 | 6.6 | 885 | 11,514 | 43.2% | 64.7% | |
| 49.25% | 67 | 6.3 | 907 | 13,964 | 52.0% | 47.6% | |
| 59.38% | 64 | 6.3 | 990 | 13,187 | 59.1% | 59.5% | |
| 60.66% | 61 | 6.3 | 1,004 | 12,193 | 68.0% | 55.6% | |
| 47.46% | 59 | 6.4 | 959 | 11,864 | 44.8% | 50.0% | |
| 57.14% | 56 | 6.1 | 847 | 10,643 | 50.0% | 68.2% | |
| 50.00% | 56 | 5.9 | 874 | 13,786 | 50.0% | 50.0% | |
| 49.09% | 55 | 6.1 | 841 | 13,390 | 50.0% | 48.4% | |
| 44.44% | 54 | 6.1 | 867 | 12,810 | 59.1% | 34.4% | |
| 50.00% | 54 | 6.2 | 740 | 11,465 | 57.1% | 42.3% | |
| 52.94% | 51 | 5.2 | 853 | 11,706 | 40.9% | 62.1% | |
| 48.00% | 50 | 6.2 | 877 | 13,507 | 61.9% | 37.9% | |
| 54.00% | 50 | 6.1 | 811 | 12,061 | 50.0% | 55.9% | |
| 46.94% | 49 | 6.2 | 838 | 12,883 | 40.0% | 51.7% | |
| 52.08% | 48 | 6.1 | 884 | 11,322 | 60.0% | 43.5% | |
| 48.94% | 47 | 5.8 | 899 | 12,001 | 41.2% | 53.3% | |
| 51.11% | 45 | 5.9 | 993 | 12,343 | 75.0% | 37.9% | |
| 47.62% | 42 | 5.8 | 858 | 12,588 | 30.8% | 55.2% | |
| 58.54% | 41 | 6.0 | 844 | 11,580 | 52.4% | 65.0% | |
| 50.00% | 40 | 6.0 | 785 | 12,693 | 47.1% | 52.2% | |
| 42.50% | 40 | 5.9 | 698 | 10,784 | 37.5% | 45.8% | |
| 58.97% | 39 | 5.7 | 798 | 12,670 | 73.3% | 50.0% | |
| 50.00% | 38 | 6.3 | 996 | 12,096 | 50.0% | 50.0% | |
| 47.37% | 38 | 5.9 | 885 | 13,006 | 31.3% | 59.1% | |
| 44.74% | 38 | 6.1 | 736 | 11,743 | 33.3% | 55.0% | |
| 44.44% | 36 | 5.3 | 712 | 11,286 | 42.9% | 46.7% | |
| 58.33% | 36 | 6.6 | 950 | 11,382 | 45.0% | 75.0% | |
| 58.33% | 36 | 6.5 | 959 | 13,118 | 53.9% | 60.9% | |
| 47.22% | 36 | 6.5 | 822 | 13,319 | 50.0% | 45.5% | |
| 44.12% | 34 | 5.4 | 794 | 11,934 | 60.0% | 31.6% | |
| 52.94% | 34 | 5.4 | 1,021 | 13,008 | 37.5% | 66.7% | |
| 56.25% | 32 | 5.2 | 877 | 13,126 | 53.9% | 57.9% | |
| 59.38% | 32 | 6.2 | 767 | 12,764 | 69.2% | 52.6% | |
| 51.61% | 31 | 6.2 | 770 | 11,717 | 40.0% | 62.5% | |
| 45.16% | 31 | 4.7 | 804 | 11,868 | 64.3% | 29.4% | |
| 45.16% | 31 | 6.3 | 975 | 12,909 | 40.0% | 50.0% | |
| 48.28% | 29 | 6.2 | 912 | 11,141 | 50.0% | 46.7% | |
| 34.48% | 29 | 6.3 | 651 | 11,676 | 7.1% | 60.0% | |
| 51.85% | 27 | 6.0 | 764 | 13,315 | 10.0% | 76.5% | |
| 42.31% | 26 | 6.4 | 866 | 12,494 | 36.4% | 46.7% | |
| 64.00% | 25 | 6.5 | 963 | 11,300 | 69.2% | 58.3% | |
| 54.17% | 24 | 6.0 | 835 | 11,089 | 70.0% | 42.9% | |
| 54.17% | 24 | 5.8 | 839 | 12,111 | 45.5% | 61.5% | |
| 39.13% | 23 | 6.1 | 733 | 12,751 | 44.4% | 35.7% | |
| 56.52% | 23 | 6.1 | 956 | 13,245 | 40.0% | 69.2% | |
| 54.55% | 22 | 6.3 | 890 | 10,650 | 36.4% | 72.7% | |
| 52.38% | 21 | 6.0 | 968 | 13,253 | 66.7% | 50.0% | |
| 42.86% | 21 | 5.6 | 842 | 11,903 | 33.3% | 46.7% | |
| 31.58% | 19 | 4.7 | 656 | 12,341 | 30.0% | 33.3% | |
| 57.89% | 19 | 6.2 | 756 | 11,625 | 54.5% | 62.5% | |
| 38.89% | 18 | 6.6 | 922 | 13,233 | 40.0% | 38.5% | |
| 52.94% | 17 | 5.0 | 644 | 10,546 | 50.0% | 60.0% | |
| 41.18% | 17 | 6.1 | 622 | 13,240 | 33.3% | 45.5% | |
| 52.94% | 17 | 6.3 | 1,028 | 13,653 | 71.4% | 40.0% | |
| 52.94% | 17 | 4.6 | 974 | 13,703 | 25.0% | 61.5% | |
| 64.71% | 17 | 6.7 | 914 | 11,709 | 37.5% | 88.9% | |
| 41.18% | 17 | 4.0 | 725 | 11,372 | 57.1% | 30.0% | |
| 50.00% | 16 | 6.1 | 866 | 11,703 | 44.4% | 57.1% | |
| 64.29% | 14 | 6.1 | 759 | 10,988 | 57.1% | 71.4% | |
| 42.86% | 14 | 5.5 | 851 | 12,390 | 50.0% | 37.5% | |
| 46.15% | 13 | 6.5 | 1,007 | 12,797 | 60.0% | 37.5% | |
| 46.15% | 13 | 1.9 | 728 | 13,230 | 33.3% | 57.1% | |
| 50.00% | 12 | 1.8 | 812 | 13,513 | 25.0% | 62.5% | |
| 50.00% | 12 | 5.7 | 874 | 13,263 | 50.0% | 50.0% | |
| 66.67% | 12 | 3.5 | 984 | 13,963 | 62.5% | 75.0% | |
| 45.45% | 11 | 5.5 | 884 | 12,966 | 0.0% | 55.6% | |
| 50.00% | 10 | 3.0 | 749 | 12,603 | 50.0% | 50.0% | |
| 40.00% | 10 | 3.8 | 648 | 12,563 | 33.3% | 50.0% | |
| 60.00% | 10 | 5.1 | 744 | 12,115 | 40.0% | 80.0% | |
| 50.00% | 10 | 6.2 | 828 | 12,426 | 50.0% | 50.0% | |
| 50.00% | 10 | 4.5 | 817 | 11,979 | 80.0% | 20.0% | |
| 55.56% | 9 | 3.3 | 722 | 11,975 | 66.7% | 50.0% | |
| 44.44% | 9 | 3.9 | 1,015 | 8,790 | 40.0% | 50.0% | |
| 55.56% | 9 | 4.9 | 677 | 11,574 | 50.0% | 60.0% | |
| 55.56% | 9 | 6.4 | 872 | 12,030 | 100.0% | 42.9% | |
| 50.00% | 8 | 5.7 | 741 | 10,834 | 50.0% | 50.0% | |
| 62.50% | 8 | 6.4 | 823 | 11,941 | 50.0% | 75.0% | |
| 25.00% | 8 | 4.4 | 818 | 12,091 | 33.3% | 20.0% | |
| 62.50% | 8 | 6.2 | 933 | 12,633 | 50.0% | 75.0% | |
| 42.86% | 7 | 4.2 | 749 | 10,214 | 40.0% | 50.0% | |
| 42.86% | 7 | 3.9 | 471 | 9,224 | 33.3% | 50.0% | |
| 42.86% | 7 | 3.8 | 794 | 13,238 | 0.0% | 60.0% | |
| 57.14% | 7 | 5.1 | 886 | 15,156 | 0.0% | 57.1% | |
| 42.86% | 7 | 5.4 | 647 | 11,864 | 50.0% | 40.0% | |
| 14.29% | 7 | 6.5 | 1,053 | 10,913 | 25.0% | 0.0% | |
| 33.33% | 6 | 3.8 | 765 | 15,452 | 50.0% | 25.0% | |
| 66.67% | 6 | 5.8 | 757 | 14,611 | 100.0% | 33.3% | |
| 16.67% | 6 | 3.2 | 674 | 11,433 | 50.0% | 0.0% | |
| 60.00% | 5 | 5.1 | 888 | 13,120 | 0.0% | 75.0% | |
| 60.00% | 5 | 5.5 | 671 | 10,764 | 0.0% | 75.0% | |
| 80.00% | 5 | 8.3 | 937 | 10,892 | 80.0% | 0.0% | |
| 0.00% | 5 | 5.1 | 693 | 9,654 | 0.0% | 0.0% | |
| 20.00% | 5 | 3.1 | 689 | 12,342 | 0.0% | 25.0% | |
| 60.00% | 5 | 4.4 | 864 | 13,281 | 0.0% | 60.0% | |
| 40.00% | 5 | 6.0 | 891 | 15,554 | 0.0% | 50.0% | |
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Vayne vs Samira - Frequently Asked Questions
How does Vayne do against Samira in League of Legends?
Samira wins the Vayne vs Samira matchup with a 50.8% win rate compared to Vayne's 49.2%, a 1.6 percentage point difference. This data is based on 189 recent ranked games in patch 26.10.
How does Vayne do against Samira in the early game?
In the early game, Samira has the advantage against Vayne with a 51.6% win rate versus 48.4%. Samira players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Samira in the late game?
In the late game, Vayne takes over the Vayne vs Samira matchup with a 50.0% win rate compared to 50.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Samira matchup?
Samira wins the matchup against Vayne with a 50.8% win rate in League of Legends patch 26.10. The 1.6 percentage point advantage means Samira is slightly favored in this lane matchup based on 189 games analyzed.
What is the best Vayne build against Samira?
The best Vayne build against Samira includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Samira?
The best Vayne runes against Samira use the Precision primary tree with Resolve secondary. This rune setup achieves a 54.3% win rate in the Vayne vs Samira matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Samira?
No, Vayne struggles against Samira with only a 49.2% win rate. Samira has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Samira's lead.
How do I play Vayne against Samira?
When playing Vayne against Samira, play cautiously and avoid Samira's power spikes. Focus on safe farming — you outscale Samira in the late game. Use the matchup-specific build and runes above to optimize your chances.
