Vaynevs Caitlyn
Vayne vs Caitlyn is a decisive matchup in LoL patch 26.14. Vayne wins with a 53.4% win rate (+6.8%) over Caitlyn based on 307 games. Caitlyn wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Caitlyn matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Caitlyn Matchup?
Vayne vs Caitlyn Matchup Summary
The Vayne vs Caitlyn matchup is a decisive matchup in League of Legends ranked play. Based on 307 recent matches analyzed, Vayne wins with a 53.4% win rate compared to Caitlyn's 46.6%, giving Vayne a 6.8 percentage point advantage. Game phase dynamics play a critical role here: Caitlyn controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Caitlyn needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Caitlyn leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Caitlyn and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Caitlyn away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Caitlyn Laning Phase Breakdown
Caitlyn is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Caitlyn holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Early Game vs Late Game
Vayne48.8%
Caitlyn51.2%Vayne56.6%Caitlyn43.4%During the early laning phase (first 15 minutes), Caitlyn has a meaningful 51.2% win rate, outperforming Vayne by 2.4 percentage points. Caitlyn players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.
Vayne is far superior in the late game (25+ minutes), boasting a 56.6% win rate — 13.2 points above Caitlyn. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
The power dynamics shift as the game progresses — Caitlyn has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Vayne Runes Against Caitlyn
Precision
Resolve
Running Precision primary with Resolve secondary allows Vayne to press their advantage against Caitlyn, amplifying the strengths that make this a favorable matchup.
Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 48.56% | 348 | 5.8 | 847 | 12,979 | 44.1% | 50.9% | |
| 53.42% | 307 | 5.9 | 839 | 12,940 | 48.8% | 56.6% | |
| 48.20% | 278 | 6.1 | 836 | 13,470 | 41.3% | 51.6% | |
| 47.74% | 243 | 6.2 | 860 | 12,610 | 47.6% | 47.9% | |
| 53.08% | 211 | 6.3 | 878 | 12,621 | 43.0% | 61.0% | |
| 41.53% | 183 | 6.1 | 773 | 12,603 | 38.8% | 43.1% | |
| 52.78% | 144 | 6.1 | 791 | 12,829 | 55.8% | 51.1% | |
| 51.91% | 131 | 6.4 | 881 | 14,083 | 40.9% | 57.5% | |
| 41.41% | 128 | 6.1 | 892 | 12,802 | 38.3% | 43.2% | |
| 49.00% | 100 | 6.3 | 952 | 13,528 | 45.7% | 50.8% | |
| 42.86% | 98 | 6.0 | 825 | 13,131 | 40.0% | 44.1% | |
| 52.75% | 91 | 6.2 | 890 | 12,275 | 55.1% | 50.0% | |
| 50.00% | 88 | 5.7 | 727 | 12,174 | 43.8% | 53.6% | |
| 51.81% | 83 | 6.1 | 910 | 11,362 | 54.5% | 50.0% | |
| 47.50% | 80 | 6.1 | 820 | 12,475 | 45.7% | 48.9% | |
| 60.00% | 65 | 6.0 | 974 | 12,774 | 68.2% | 55.8% | |
| 50.00% | 64 | 6.0 | 847 | 11,777 | 46.1% | 52.6% | |
| 62.50% | 64 | 6.1 | 899 | 12,623 | 66.7% | 58.8% | |
| 33.33% | 60 | 5.7 | 698 | 10,500 | 28.6% | 37.5% | |
| 64.91% | 57 | 6.1 | 1,042 | 12,267 | 60.0% | 68.8% | |
| 50.88% | 57 | 6.1 | 787 | 12,253 | 54.8% | 46.1% | |
| 53.57% | 56 | 5.8 | 725 | 12,485 | 43.5% | 60.6% | |
| 47.17% | 53 | 6.4 | 721 | 12,526 | 33.3% | 58.6% | |
| 45.28% | 53 | 5.7 | 745 | 11,425 | 48.1% | 42.3% | |
| 40.38% | 52 | 6.0 | 807 | 12,805 | 42.9% | 38.7% | |
| 52.00% | 50 | 5.6 | 757 | 10,827 | 71.4% | 37.9% | |
| 24.00% | 50 | 5.5 | 593 | 10,367 | 10.5% | 32.3% | |
| 50.00% | 48 | 6.3 | 804 | 12,299 | 37.5% | 62.5% | |
| 43.48% | 46 | 5.9 | 831 | 13,246 | 40.0% | 46.1% | |
| 64.44% | 45 | 6.6 | 1,356 | 13,355 | 52.9% | 71.4% | |
| 44.19% | 43 | 6.5 | 783 | 12,296 | 42.9% | 45.5% | |
| 48.78% | 41 | 6.2 | 879 | 13,464 | 28.6% | 59.3% | |
| 52.94% | 34 | 6.7 | 896 | 13,048 | 50.0% | 55.6% | |
| 63.64% | 33 | 6.5 | 1,116 | 12,112 | 53.3% | 72.2% | |
| 62.50% | 32 | 6.3 | 819 | 12,631 | 45.5% | 71.4% | |
| 59.38% | 32 | 6.1 | 854 | 12,126 | 88.9% | 47.8% | |
| 38.71% | 31 | 5.7 | 1,025 | 11,464 | 27.3% | 45.0% | |
| 54.84% | 31 | 5.8 | 820 | 11,578 | 20.0% | 71.4% | |
| 67.74% | 31 | 6.0 | 1,055 | 12,463 | 54.5% | 75.0% | |
| 43.33% | 30 | 6.2 | 879 | 12,495 | 36.4% | 47.4% | |
| 53.33% | 30 | 6.5 | 1,296 | 14,350 | 44.4% | 57.1% | |
| 42.86% | 28 | 5.9 | 832 | 12,552 | 36.4% | 47.1% | |
| 66.67% | 27 | 6.3 | 893 | 10,712 | 69.2% | 64.3% | |
| 62.96% | 27 | 6.3 | 1,010 | 10,804 | 57.1% | 69.2% | |
| 51.85% | 27 | 6.6 | 827 | 11,719 | 60.0% | 47.1% | |
| 40.00% | 25 | 5.9 | 1,076 | 12,666 | 55.6% | 31.3% | |
| 66.67% | 24 | 6.3 | 851 | 11,368 | 75.0% | 58.3% | |
| 41.67% | 24 | 6.5 | 982 | 11,958 | 53.9% | 27.3% | |
| 39.13% | 23 | 5.3 | 808 | 11,110 | 11.1% | 57.1% | |
| 43.48% | 23 | 5.9 | 903 | 12,039 | 40.0% | 44.4% | |
| 52.17% | 23 | 6.3 | 716 | 12,158 | 50.0% | 53.3% | |
| 50.00% | 22 | 6.3 | 786 | 12,373 | 50.0% | 50.0% | |
| 50.00% | 22 | 6.3 | 877 | 11,269 | 33.3% | 61.5% | |
| 54.55% | 22 | 6.1 | 944 | 13,476 | 50.0% | 56.3% | |
| 50.00% | 22 | 5.7 | 857 | 10,867 | 66.7% | 38.5% | |
| 61.90% | 21 | 5.7 | 807 | 11,322 | 55.6% | 66.7% | |
| 38.10% | 21 | 6.1 | 885 | 12,478 | 66.7% | 26.7% | |
| 47.62% | 21 | 6.3 | 794 | 14,046 | 33.3% | 50.0% | |
| 40.00% | 20 | 6.1 | 896 | 12,759 | 40.0% | 40.0% | |
| 68.42% | 19 | 6.1 | 951 | 10,335 | 75.0% | 63.6% | |
| 57.89% | 19 | 6.3 | 813 | 12,245 | 50.0% | 63.6% | |
| 50.00% | 18 | 5.8 | 938 | 11,873 | 55.6% | 44.4% | |
| 70.59% | 17 | 6.4 | 1,041 | 13,115 | 80.0% | 66.7% | |
| 56.25% | 16 | 6.5 | 811 | 14,119 | 50.0% | 58.3% | |
| 43.75% | 16 | 5.6 | 733 | 11,696 | 28.6% | 55.6% | |
| 31.25% | 16 | 6.0 | 738 | 11,878 | 40.0% | 27.3% | |
| 62.50% | 16 | 6.2 | 946 | 12,972 | 50.0% | 70.0% | |
| 46.67% | 15 | 6.0 | 661 | 9,616 | 55.6% | 33.3% | |
| 66.67% | 15 | 6.2 | 938 | 14,618 | 25.0% | 81.8% | |
| 78.57% | 14 | 6.8 | 918 | 15,770 | 100.0% | 70.0% | |
| 35.71% | 14 | 6.2 | 906 | 9,942 | 33.3% | 37.5% | |
| 71.43% | 14 | 6.4 | 846 | 13,112 | 42.9% | 100.0% | |
| 64.29% | 14 | 6.1 | 1,149 | 12,061 | 57.1% | 71.4% | |
| 53.85% | 13 | 5.9 | 810 | 13,109 | 33.3% | 60.0% | |
| 53.85% | 13 | 5.4 | 1,017 | 13,231 | 50.0% | 57.1% | |
| 53.85% | 13 | 5.8 | 757 | 10,865 | 75.0% | 20.0% | |
| 50.00% | 12 | 6.3 | 894 | 13,153 | 25.0% | 62.5% | |
| 58.33% | 12 | 6.5 | 863 | 10,158 | 33.3% | 83.3% | |
| 41.67% | 12 | 4.4 | 890 | 10,679 | 50.0% | 25.0% | |
| 54.55% | 11 | 5.7 | 764 | 12,344 | 33.3% | 62.5% | |
| 50.00% | 10 | 6.4 | 838 | 12,063 | 66.7% | 42.9% | |
| 80.00% | 10 | 6.0 | 847 | 12,029 | 100.0% | 66.7% | |
| 33.33% | 9 | 5.0 | 723 | 12,686 | 0.0% | 50.0% | |
| 22.22% | 9 | 4.0 | 782 | 13,444 | 0.0% | 33.3% | |
| 66.67% | 9 | 4.3 | 882 | 14,962 | 100.0% | 62.5% | |
| 77.78% | 9 | 5.5 | 792 | 15,017 | 100.0% | 71.4% | |
| 25.00% | 8 | 6.4 | 866 | 11,042 | 50.0% | 0.0% | |
| 37.50% | 8 | 4.5 | 780 | 11,842 | 50.0% | 33.3% | |
| 12.50% | 8 | 4.4 | 823 | 11,955 | 25.0% | 0.0% | |
| 71.43% | 7 | 6.4 | 795 | 13,702 | 50.0% | 80.0% | |
| 42.86% | 7 | 4.8 | 522 | 10,756 | 33.3% | 50.0% | |
| 33.33% | 6 | 6.0 | 825 | 14,164 | 0.0% | 40.0% | |
| 50.00% | 6 | 3.2 | 462 | 10,339 | 66.7% | 33.3% | |
| 16.67% | 6 | 5.1 | 933 | 11,156 | 33.3% | 0.0% | |
| 50.00% | 6 | 4.0 | 739 | 8,973 | 50.0% | 50.0% | |
| 50.00% | 6 | 3.1 | 630 | 7,383 | 50.0% | 50.0% | |
| 83.33% | 6 | 5.5 | 718 | 14,890 | 100.0% | 80.0% | |
| 66.67% | 6 | 5.9 | 979 | 16,504 | 0.0% | 66.7% | |
| 16.67% | 6 | 4.7 | 846 | 11,283 | 0.0% | 25.0% | |
| 40.00% | 5 | 0.7 | 512 | 11,183 | 33.3% | 50.0% | |
| 0.00% | 5 | 5.7 | 822 | 10,600 | 0.0% | 0.0% | |
| 60.00% | 5 | 6.9 | 792 | 12,100 | 50.0% | 66.7% | |
| 60.00% | 5 | 4.2 | 988 | 15,386 | 0.0% | 60.0% | |
| 40.00% | 5 | 4.5 | 714 | 9,282 | 66.7% | 0.0% | |
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Vayne vs Caitlyn - Frequently Asked Questions
How does Vayne do against Caitlyn in League of Legends?
Vayne wins the Vayne vs Caitlyn matchup with a 53.4% win rate compared to Caitlyn's 46.6%, a 6.8 percentage point difference. This data is based on 307 recent ranked games in patch 26.14.
How does Vayne do against Caitlyn in the early game?
In the early game, Caitlyn has the advantage against Vayne with a 51.2% win rate versus 48.8%. Caitlyn players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Caitlyn in the late game?
In the late game, Vayne takes over the Vayne vs Caitlyn matchup with a 56.6% win rate compared to 43.4%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Caitlyn matchup?
Vayne wins the matchup against Caitlyn with a 53.4% win rate in League of Legends patch 26.14. The 6.8 percentage point advantage means Vayne is significantly favored in this lane matchup based on 307 games analyzed.
What is the best Vayne build against Caitlyn?
The best Vayne build against Caitlyn includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Caitlyn?
The best Vayne runes against Caitlyn use the Precision primary tree with Resolve secondary. This rune setup achieves a 64.5% win rate in the Vayne vs Caitlyn matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Caitlyn?
Yes, Vayne has a favorable matchup against Caitlyn with a 53.4% win rate. Vayne strongly counters Caitlyn in lane based on current patch 26.14 data.
How do I play Vayne against Caitlyn?
When playing Vayne against Caitlyn, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Caitlyn. Build the recommended items and runes for this specific matchup for the best results.