Vaynevs Caitlyn
Vayne vs Caitlyn is a decisive matchup in LoL patch 26.11. Caitlyn wins with a 54.0% win rate (+8.0%) over Vayne based on 476 games. Caitlyn holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Caitlyn matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Caitlyn Matchup?
Vayne vs Caitlyn Matchup Summary
The Vayne vs Caitlyn matchup is a decisive matchup in League of Legends ranked play. Based on 476 recent matches analyzed, Caitlyn wins with a 54.0% win rate compared to Vayne's 46.0%, giving Caitlyn a 8.0 percentage point advantage. Caitlyn dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Caitlyn leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Caitlyn has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Caitlyn overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Caitlyn Laning Phase Breakdown
Caitlyn is favored during the laning phase against Vayne, winning 4 out of 5 key stat categories. Caitlyn holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Vayne Build Against Caitlyn
Berserker's Greaves is the optimal boots choice against Caitlyn, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Caitlyn are Kraken Slayer, Blade of The Ruined King and Randuin's Omen. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Caitlyn. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Caitlyn matchup.
Early Game vs Late Game
Vayne44.3%
Caitlyn55.7%Vayne47.4%Caitlyn52.6%Caitlyn dominates the early game (first 15 minutes) with a commanding 55.7% win rate — a 11.3 percentage point lead over Vayne. This lopsided early game means Caitlyn can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Caitlyn is far superior in the late game (25+ minutes), boasting a 52.6% win rate — 5.3 points above Vayne. Extended games heavily favor Caitlyn, whose kit and scaling make them a dominant force in team fights and objective control.
Caitlyn holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Caitlyn
Precision
Domination
The Precision and Domination rune setup gives Vayne the best tools to compete against Caitlyn in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 46.01% | 476 | 6.0 | 789 | 12,875 | 44.3% | 47.4% | |
| 47.20% | 447 | 6.0 | 791 | 12,725 | 45.4% | 48.6% | |
| 46.26% | 428 | 5.7 | 796 | 12,715 | 44.9% | 47.3% | |
| 53.92% | 395 | 6.0 | 857 | 12,968 | 53.2% | 54.6% | |
| 47.85% | 372 | 6.2 | 894 | 13,189 | 46.8% | 48.6% | |
| 52.99% | 351 | 6.2 | 843 | 13,142 | 52.5% | 53.4% | |
| 52.98% | 285 | 6.3 | 904 | 13,456 | 46.2% | 58.8% | |
| 53.90% | 269 | 6.3 | 877 | 13,737 | 48.2% | 58.0% | |
| 52.38% | 189 | 5.9 | 886 | 12,468 | 46.1% | 58.2% | |
| 51.92% | 156 | 6.5 | 913 | 11,989 | 50.0% | 53.4% | |
| 54.30% | 151 | 6.1 | 859 | 13,227 | 58.5% | 51.2% | |
| 50.33% | 151 | 6.1 | 804 | 13,007 | 43.8% | 55.2% | |
| 45.95% | 148 | 5.9 | 780 | 13,603 | 45.3% | 46.3% | |
| 45.38% | 130 | 6.1 | 776 | 13,081 | 38.2% | 50.7% | |
| 47.83% | 115 | 6.4 | 812 | 13,765 | 38.5% | 52.6% | |
| 42.61% | 115 | 6.1 | 781 | 12,082 | 34.0% | 49.2% | |
| 50.88% | 114 | 5.8 | 866 | 12,989 | 41.2% | 58.7% | |
| 45.19% | 104 | 6.4 | 899 | 13,175 | 48.7% | 43.1% | |
| 59.80% | 102 | 6.5 | 854 | 13,189 | 63.5% | 56.0% | |
| 31.00% | 100 | 5.5 | 635 | 10,360 | 11.1% | 47.3% | |
| 45.83% | 96 | 5.8 | 857 | 13,164 | 44.4% | 46.7% | |
| 50.53% | 95 | 6.3 | 1,120 | 12,737 | 51.6% | 50.0% | |
| 58.06% | 93 | 6.3 | 796 | 13,008 | 54.8% | 60.8% | |
| 44.09% | 93 | 5.8 | 625 | 11,330 | 42.4% | 45.0% | |
| 45.56% | 90 | 5.8 | 830 | 11,355 | 43.6% | 47.1% | |
| 45.98% | 87 | 6.3 | 851 | 13,572 | 37.9% | 50.0% | |
| 55.81% | 86 | 6.1 | 899 | 10,748 | 43.2% | 65.3% | |
| 55.95% | 84 | 6.2 | 1,292 | 11,546 | 51.4% | 59.2% | |
| 56.41% | 78 | 6.3 | 883 | 13,435 | 57.1% | 55.8% | |
| 54.84% | 62 | 5.9 | 814 | 12,061 | 58.3% | 52.6% | |
| 45.76% | 59 | 6.2 | 877 | 12,775 | 48.0% | 44.1% | |
| 51.92% | 52 | 6.0 | 913 | 11,592 | 48.1% | 56.0% | |
| 45.10% | 51 | 6.5 | 921 | 12,144 | 40.9% | 48.3% | |
| 52.00% | 50 | 6.0 | 875 | 13,621 | 47.8% | 55.6% | |
| 35.42% | 48 | 6.2 | 721 | 10,982 | 28.0% | 43.5% | |
| 58.33% | 48 | 6.1 | 989 | 11,810 | 64.0% | 52.2% | |
| 45.83% | 48 | 6.2 | 1,005 | 10,838 | 51.9% | 38.1% | |
| 50.00% | 46 | 6.2 | 970 | 13,364 | 47.4% | 51.9% | |
| 58.70% | 46 | 6.2 | 914 | 13,671 | 62.5% | 54.5% | |
| 54.55% | 44 | 6.2 | 874 | 14,063 | 57.1% | 53.3% | |
| 44.19% | 43 | 6.6 | 839 | 13,744 | 55.0% | 34.8% | |
| 26.19% | 42 | 5.9 | 874 | 11,678 | 23.5% | 28.0% | |
| 48.78% | 41 | 5.9 | 836 | 11,644 | 43.5% | 55.6% | |
| 52.50% | 40 | 5.6 | 838 | 13,607 | 37.5% | 56.3% | |
| 38.46% | 39 | 6.7 | 854 | 10,961 | 50.0% | 28.6% | |
| 41.03% | 39 | 6.0 | 743 | 9,571 | 28.6% | 55.6% | |
| 67.57% | 37 | 6.5 | 898 | 11,526 | 62.5% | 76.9% | |
| 45.95% | 37 | 5.6 | 832 | 11,998 | 40.0% | 50.0% | |
| 52.94% | 34 | 6.4 | 759 | 12,245 | 50.0% | 54.5% | |
| 52.94% | 34 | 6.4 | 1,051 | 11,474 | 52.6% | 53.3% | |
| 66.67% | 33 | 6.3 | 938 | 13,524 | 61.5% | 70.0% | |
| 48.48% | 33 | 6.4 | 784 | 11,269 | 50.0% | 46.1% | |
| 48.48% | 33 | 6.5 | 979 | 13,305 | 62.5% | 44.0% | |
| 40.63% | 32 | 5.3 | 820 | 11,344 | 42.1% | 38.5% | |
| 62.50% | 32 | 5.7 | 796 | 13,163 | 41.7% | 75.0% | |
| 40.63% | 32 | 6.2 | 676 | 10,369 | 31.6% | 53.9% | |
| 58.06% | 31 | 6.4 | 849 | 12,138 | 64.3% | 52.9% | |
| 53.33% | 30 | 5.6 | 855 | 12,152 | 55.6% | 52.4% | |
| 60.00% | 30 | 6.0 | 953 | 12,308 | 76.9% | 47.1% | |
| 43.33% | 30 | 6.6 | 646 | 11,441 | 37.5% | 50.0% | |
| 55.56% | 27 | 5.3 | 792 | 11,006 | 50.0% | 60.0% | |
| 48.15% | 27 | 6.2 | 834 | 11,465 | 43.8% | 54.5% | |
| 50.00% | 26 | 5.9 | 693 | 11,801 | 41.7% | 57.1% | |
| 50.00% | 26 | 6.1 | 710 | 11,421 | 46.1% | 53.9% | |
| 30.77% | 26 | 5.3 | 700 | 11,001 | 27.3% | 33.3% | |
| 50.00% | 26 | 5.8 | 834 | 12,301 | 54.5% | 46.7% | |
| 48.00% | 25 | 6.0 | 816 | 12,910 | 20.0% | 66.7% | |
| 44.00% | 25 | 6.4 | 758 | 11,844 | 50.0% | 38.5% | |
| 54.17% | 24 | 6.3 | 991 | 12,325 | 64.3% | 40.0% | |
| 45.83% | 24 | 6.0 | 850 | 11,125 | 57.1% | 30.0% | |
| 56.52% | 23 | 5.7 | 610 | 10,299 | 45.5% | 66.7% | |
| 45.45% | 22 | 6.5 | 734 | 12,184 | 38.5% | 55.6% | |
| 40.91% | 22 | 6.0 | 806 | 12,815 | 44.4% | 38.5% | |
| 42.11% | 19 | 6.2 | 920 | 10,372 | 45.5% | 37.5% | |
| 63.16% | 19 | 6.3 | 870 | 12,589 | 50.0% | 72.7% | |
| 42.11% | 19 | 5.8 | 817 | 12,142 | 57.1% | 33.3% | |
| 61.11% | 18 | 5.6 | 1,008 | 13,433 | 66.7% | 58.3% | |
| 62.50% | 16 | 6.1 | 885 | 11,547 | 62.5% | 62.5% | |
| 80.00% | 15 | 2.2 | 885 | 17,368 | 50.0% | 84.6% | |
| 53.33% | 15 | 6.4 | 985 | 13,301 | 50.0% | 54.5% | |
| 60.00% | 15 | 6.5 | 833 | 11,244 | 37.5% | 85.7% | |
| 46.67% | 15 | 6.6 | 876 | 11,530 | 50.0% | 42.9% | |
| 46.67% | 15 | 5.4 | 916 | 13,992 | 25.0% | 54.5% | |
| 42.86% | 14 | 6.4 | 824 | 13,966 | 75.0% | 30.0% | |
| 42.86% | 14 | 6.0 | 841 | 13,447 | 0.0% | 66.7% | |
| 53.85% | 13 | 6.5 | 849 | 13,506 | 100.0% | 33.3% | |
| 46.15% | 13 | 5.2 | 750 | 11,579 | 50.0% | 42.9% | |
| 66.67% | 12 | 5.6 | 1,025 | 12,928 | 80.0% | 57.1% | |
| 33.33% | 12 | 6.0 | 927 | 11,900 | 33.3% | 33.3% | |
| 54.55% | 11 | 5.6 | 1,002 | 13,298 | 50.0% | 57.1% | |
| 63.64% | 11 | 6.1 | 642 | 10,204 | 50.0% | 80.0% | |
| 54.55% | 11 | 2.9 | 820 | 14,068 | 66.7% | 40.0% | |
| 81.82% | 11 | 6.2 | 775 | 12,783 | 100.0% | 71.4% | |
| 54.55% | 11 | 3.4 | 846 | 13,743 | 33.3% | 62.5% | |
| 54.55% | 11 | 5.5 | 761 | 11,649 | 71.4% | 25.0% | |
| 45.45% | 11 | 5.6 | 915 | 9,808 | 75.0% | 28.6% | |
| 40.00% | 10 | 4.6 | 708 | 11,732 | 50.0% | 25.0% | |
| 60.00% | 10 | 5.7 | 820 | 12,597 | 50.0% | 62.5% | |
| 50.00% | 10 | 3.8 | 771 | 13,237 | 33.3% | 57.1% | |
| 40.00% | 10 | 5.5 | 926 | 11,893 | 40.0% | 40.0% | |
| 66.67% | 9 | 3.8 | 1,039 | 13,798 | 66.7% | 66.7% | |
| 33.33% | 9 | 6.1 | 1,076 | 13,273 | 0.0% | 50.0% | |
| 55.56% | 9 | 6.7 | 930 | 13,145 | 100.0% | 20.0% | |
| 33.33% | 9 | 6.0 | 855 | 13,018 | 33.3% | 33.3% | |
| 55.56% | 9 | 3.9 | 860 | 12,860 | 33.3% | 66.7% | |
| 50.00% | 8 | 5.8 | 870 | 14,565 | 50.0% | 50.0% | |
| 62.50% | 8 | 7.3 | 684 | 11,847 | 66.7% | 50.0% | |
| 50.00% | 8 | 3.2 | 883 | 13,479 | 75.0% | 25.0% | |
| 25.00% | 8 | 5.2 | 690 | 9,102 | 16.7% | 50.0% | |
| 37.50% | 8 | 5.8 | 526 | 9,894 | 50.0% | 25.0% | |
| 57.14% | 7 | 4.0 | 760 | 10,750 | 33.3% | 75.0% | |
| 71.43% | 7 | 3.6 | 743 | 11,425 | 80.0% | 50.0% | |
| 42.86% | 7 | 4.5 | 723 | 11,697 | 33.3% | 50.0% | |
| 28.57% | 7 | 4.5 | 676 | 12,046 | 0.0% | 40.0% | |
| 50.00% | 6 | 3.5 | 781 | 15,022 | 0.0% | 60.0% | |
| 33.33% | 6 | 6.8 | 823 | 13,779 | 0.0% | 50.0% | |
| 33.33% | 6 | 2.9 | 989 | 12,898 | 33.3% | 33.3% | |
| 66.67% | 6 | 5.9 | 1,006 | 14,143 | 50.0% | 75.0% | |
| 20.00% | 5 | 4.7 | 577 | 8,999 | 33.3% | 0.0% | |
| 40.00% | 5 | 2.1 | 611 | 12,290 | 50.0% | 0.0% | |
| 40.00% | 5 | 6.4 | 1,176 | 14,594 | 0.0% | 50.0% | |
| 80.00% | 5 | 6.2 | 1,024 | 13,762 | 100.0% | 66.7% | |
| 40.00% | 5 | 5.9 | 962 | 13,248 | 0.0% | 50.0% | |
| 40.00% | 5 | 6.0 | 673 | 9,218 | 50.0% | 0.0% | |
| 40.00% | 5 | 6.4 | 726 | 9,892 | 40.0% | 0.0% | |
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Vayne vs Caitlyn - Frequently Asked Questions
How does Vayne do against Caitlyn in League of Legends?
Caitlyn wins the Vayne vs Caitlyn matchup with a 54.0% win rate compared to Vayne's 46.0%, a 8.0 percentage point difference. This data is based on 476 recent ranked games in patch 26.11.
How does Vayne do against Caitlyn in the early game?
In the early game, Caitlyn has the advantage against Vayne with a 55.7% win rate versus 44.3%. Caitlyn players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Caitlyn in the late game?
In the late game, Caitlyn takes over the Vayne vs Caitlyn matchup with a 52.6% win rate compared to 47.4%. Caitlyn scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Caitlyn matchup?
Caitlyn wins the matchup against Vayne with a 54.0% win rate in League of Legends patch 26.11. The 8.0 percentage point advantage means Caitlyn is significantly favored in this lane matchup based on 476 games analyzed.
What is the best Vayne build against Caitlyn?
The best Vayne build against Caitlyn includes Kraken Slayer, Blade of The Ruined King, Randuin's Omen with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Caitlyn?
The best Vayne runes against Caitlyn use the Precision primary tree with Domination secondary. This rune setup achieves a 56.4% win rate in the Vayne vs Caitlyn matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Caitlyn?
No, Vayne struggles against Caitlyn with only a 46.0% win rate. Caitlyn has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Caitlyn's lead.
How do I play Vayne against Caitlyn?
When playing Vayne against Caitlyn, play cautiously and avoid Caitlyn's power spikes. Look for jungle assistance and team-dependent plays since Caitlyn has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.