Vaynevs Miss Fortune
Vayne vs Miss Fortune is a decisive matchup in LoL patch 26.18. Miss Fortune wins with a 56.9% win rate (+13.7%) over Vayne based on 204 games. Miss Fortune holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Miss Fortune matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Vayne vs Miss Fortune?
Vayne wins 43.5% of these games. With this many games the true rate is most likely between 36.7% and 50.6% (95% range).
- Expected
- 47.6% From both champions' overall Bot win rates
- Matchup effect
- −4.1 pts Observed minus expected
- Sample
- 193 games Lane: Bot
Lane: Bot · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.18 · Sep 11 – Sep 14
Key takeaways
- Current data slightly favors Miss Fortune, but the sample is too limited for a strong conclusion: Vayne wins 43.5% of 193 games (95% range 36.7–50.6%).
- Both champions' overall Bot win rates predict 47.6% for Vayne; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Miss Fortune usually wins the lane: 501 gold ahead of Vayne at 15 minutes on average (192 games with a 15-minute snapshot).
- Vayne players pick Blade of The Ruined King far more often against Miss Fortune: 60.3% of their other Bot games, 70.5% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Vayne and Miss Fortune played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Vayne's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Vayne vs Miss Fortune Laning Stats
At 15 minutes
Solo kills are tracked from this patch on — 0 games have them so far, shown from 30.
Whole-game averages
Vayne vs Miss Fortune Win Rate by Game Length
Vayne's win rate against Miss Fortune by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Vayne's results against Miss Fortune in short and long games are within the margin of error of each other.
Vayne vs Miss Fortune Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)Miss FortuneVayne gold at 15: −501
- First itemMiss FortuneVayne: 13.1 min · Miss Fortune: 11.1 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenVayne wins 52.1% of 71 games
- 30+ min gamesMiss FortuneVayne wins 40.0% of 115 games
What Vayne Changes Against Miss Fortune
Choices Vayne players make noticeably more or less often in this matchup than in their other Bot games.
Usually60.3%vs Miss Fortune70.5%+10.2 pts39.0% WR here
DominationSecondary treeUsually22.0%vs Miss Fortune29.5%+7.6 pts43.9% WR here
Taste of BloodRuneUsually15.8%vs Miss Fortune21.8%+5.9 pts40.5% WR here- Q > W > Ethe Q > W > E skill orderSkill priorityUsually85.2%vs Miss Fortune79.3%−5.9 pts42.5% WR here
Best Vayne Build vs Miss Fortune
Usual Vayne build (Bot)
64.7% win rate · 102 games
Against Miss Fortune
53.3% win rate · 30 games
Limited sample: 30 of 137 games finished this exact core, so treat it as an observation rather than a recommendation.
- Vayne usually completes Blade of The Ruined King first, at 13.1 min (median of 109 games).
- Miss Fortune usually completes The Collector first, at 11.1 min (median of 78 games).
- Skill priority: Q > W > E — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Vayne Runes vs Miss Fortune
Usual Vayne runes (Bot)
Lethal Tempo
50.4% win rate · 1,377 games
Against Miss Fortune
Lethal Tempo40.0% win rate · 85 games
Vayne matchup data for League of Legends patch 26.18. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Vayne Matchups
Hardest for Vayne
Easiest for Vayne
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
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Vayne vs Miss Fortune FAQ - Patch 26.18
Who wins Vayne vs Miss Fortune?
Current data slightly favors Miss Fortune, but the sample is too limited for a strong conclusion: Vayne wins 43.5% of 193 games (95% range 36.7–50.6%).
What is Vayne's win rate against Miss Fortune?
Vayne wins 43.5% of 193 Bot games against Miss Fortune on patch 26.18 (95% range 36.7–50.6%). Based on both champions' overall Bot win rates, 47.6% would be expected.
Does Vayne counter Miss Fortune?
Not clearly. Vayne wins 43.5% of 193 games against Miss Fortune, and the 95% range (36.7–50.6%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Vayne or Miss Fortune?
Miss Fortune usually wins the lane: 501 gold ahead of Vayne at 15 minutes on average (192 games with a 15-minute snapshot).
Does Vayne outscale Miss Fortune?
There are too few games of each length to tell yet.
When is Miss Fortune strongest against Vayne?
Miss Fortune is measurably ahead in: Lane (15 min), First item, 30+ min games.
What should Vayne build against Miss Fortune?
The most successful Vayne core against Miss Fortune is Terminus, Blade of The Ruined King, Guinsoo's Rageblade (53.3% over 30 games). The biggest change against Miss Fortune: Blade of The Ruined King (60.3% usually, 70.5% here).
What runes should Vayne use against Miss Fortune?
Lethal Tempo with Precision and Resolve — 40.0% over 85 games against Miss Fortune. The biggest change against Miss Fortune: Domination (22.0% usually, 29.5% here).