Vaynevs Miss Fortune
Vayne vs Miss Fortune is a very close matchup in LoL patch 26.7. Miss Fortune wins with a 51.0% win rate (+2.0%) over Vayne based on 302 games. Miss Fortune wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Miss Fortune matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Miss Fortune(49.0%)Who Wins the Vayne vs Miss Fortune Matchup?
Vayne vs Miss Fortune Matchup Summary
The Vayne vs Miss Fortune matchup is a very close matchup in League of Legends ranked play. Based on 302 recent matches analyzed, Miss Fortune wins with a 51.0% win rate compared to Vayne's 49.0%, giving Miss Fortune a 2.0 percentage point advantage. Game phase dynamics play a critical role here: Miss Fortune controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Miss Fortune needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Vayne leads by 0.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Miss Fortune is slightly favored, Vayne can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Miss Fortune's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Miss Fortune Laning Phase Breakdown
Miss Fortune is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Miss Fortune holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Early Game vs Late Game
Vayne47.5%Miss Fortune52.5%Vayne50.3%Miss Fortune49.7%Miss Fortune dominates the early game (first 15 minutes) with a commanding 52.5% win rate — a 5.0 percentage point lead over Vayne. This lopsided early game means Miss Fortune can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Vayne at 50.3% win rate — only 0.6 points ahead of Miss Fortune. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
The power dynamics shift as the game progresses — Miss Fortune has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Vayne Runes Against Miss Fortune
Precision
Domination
The Precision primary with Domination secondary combination helps Vayne maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Miss Fortune.
Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.02% | 357 | 6.0 | 817 | 13,231 | 45.3% | 52.0% | |
| 52.47% | 324 | 6.2 | 898 | 13,596 | 49.3% | 55.2% | |
| 48.09% | 314 | 6.2 | 832 | 12,819 | 44.0% | 52.7% | |
| 49.01% | 302 | 5.9 | 825 | 12,937 | 47.5% | 50.3% | |
| 52.94% | 272 | 6.0 | 839 | 13,071 | 52.8% | 53.1% | |
| 45.37% | 227 | 6.4 | 960 | 14,254 | 46.9% | 44.2% | |
| 50.00% | 222 | 6.4 | 937 | 13,717 | 50.0% | 50.0% | |
| 52.71% | 203 | 6.5 | 856 | 13,741 | 48.9% | 56.0% | |
| 52.32% | 151 | 6.5 | 828 | 13,287 | 55.4% | 49.4% | |
| 58.39% | 149 | 6.6 | 953 | 12,700 | 51.6% | 63.5% | |
| 51.30% | 115 | 5.8 | 813 | 13,717 | 61.5% | 42.9% | |
| 47.71% | 109 | 6.0 | 882 | 13,239 | 38.2% | 57.4% | |
| 55.67% | 97 | 6.4 | 880 | 12,625 | 59.6% | 51.1% | |
| 51.55% | 97 | 6.3 | 806 | 12,735 | 52.5% | 50.0% | |
| 50.00% | 94 | 5.9 | 832 | 13,595 | 46.7% | 53.1% | |
| 36.36% | 88 | 6.2 | 790 | 12,983 | 30.0% | 41.7% | |
| 47.44% | 78 | 6.6 | 928 | 13,284 | 46.3% | 48.6% | |
| 61.33% | 75 | 6.6 | 924 | 12,102 | 66.7% | 55.6% | |
| 55.56% | 72 | 6.1 | 858 | 13,247 | 45.2% | 63.4% | |
| 57.35% | 68 | 6.0 | 853 | 13,574 | 56.0% | 58.1% | |
| 36.76% | 68 | 6.2 | 881 | 12,394 | 36.7% | 36.8% | |
| 52.54% | 59 | 6.3 | 837 | 12,518 | 48.5% | 57.7% | |
| 42.37% | 59 | 6.2 | 870 | 12,828 | 34.4% | 51.9% | |
| 38.60% | 57 | 5.7 | 605 | 11,225 | 40.0% | 37.0% | |
| 37.50% | 56 | 5.5 | 601 | 10,770 | 30.4% | 42.4% | |
| 43.40% | 53 | 6.2 | 1,045 | 12,467 | 44.4% | 42.3% | |
| 44.00% | 50 | 6.1 | 886 | 13,061 | 47.8% | 40.7% | |
| 53.06% | 49 | 6.1 | 1,214 | 13,804 | 50.0% | 55.2% | |
| 65.91% | 44 | 6.1 | 869 | 13,292 | 66.7% | 65.4% | |
| 56.82% | 44 | 5.6 | 921 | 14,047 | 61.1% | 53.9% | |
| 43.18% | 44 | 5.7 | 996 | 11,548 | 31.3% | 50.0% | |
| 50.00% | 40 | 6.3 | 848 | 13,584 | 35.3% | 60.9% | |
| 55.00% | 40 | 5.9 | 893 | 14,588 | 23.1% | 70.4% | |
| 57.50% | 40 | 6.3 | 951 | 14,248 | 60.0% | 56.7% | |
| 48.72% | 39 | 6.5 | 952 | 13,491 | 57.9% | 40.0% | |
| 57.89% | 38 | 6.0 | 1,029 | 12,413 | 55.0% | 61.1% | |
| 42.11% | 38 | 6.1 | 923 | 13,741 | 44.4% | 40.0% | |
| 54.05% | 37 | 7.0 | 928 | 11,692 | 52.4% | 56.3% | |
| 40.54% | 37 | 5.8 | 804 | 12,225 | 41.2% | 40.0% | |
| 40.00% | 35 | 5.7 | 1,141 | 11,808 | 38.9% | 41.2% | |
| 55.88% | 34 | 6.5 | 856 | 11,125 | 57.9% | 53.3% | |
| 50.00% | 32 | 6.0 | 986 | 13,599 | 66.7% | 43.5% | |
| 66.67% | 30 | 6.2 | 896 | 12,540 | 50.0% | 81.3% | |
| 56.67% | 30 | 6.2 | 981 | 13,896 | 53.9% | 58.8% | |
| 48.28% | 29 | 6.7 | 858 | 12,180 | 28.6% | 66.7% | |
| 55.17% | 29 | 6.3 | 1,024 | 13,694 | 62.5% | 46.1% | |
| 51.85% | 27 | 5.7 | 984 | 12,391 | 45.5% | 56.3% | |
| 61.54% | 26 | 6.1 | 851 | 11,719 | 61.5% | 61.5% | |
| 64.00% | 25 | 6.0 | 808 | 11,770 | 55.6% | 68.8% | |
| 44.00% | 25 | 6.8 | 927 | 12,263 | 42.9% | 45.5% | |
| 33.33% | 24 | 6.4 | 835 | 11,605 | 41.7% | 25.0% | |
| 56.52% | 23 | 5.5 | 921 | 12,424 | 62.5% | 53.3% | |
| 43.48% | 23 | 6.3 | 837 | 12,921 | 60.0% | 30.8% | |
| 40.91% | 22 | 6.6 | 788 | 11,101 | 41.7% | 40.0% | |
| 52.38% | 21 | 5.9 | 923 | 13,477 | 40.0% | 63.6% | |
| 60.00% | 20 | 5.2 | 909 | 14,352 | 20.0% | 73.3% | |
| 47.37% | 19 | 6.9 | 1,008 | 11,892 | 63.6% | 25.0% | |
| 50.00% | 18 | 6.2 | 732 | 13,045 | 60.0% | 37.5% | |
| 50.00% | 18 | 6.2 | 1,053 | 12,784 | 55.6% | 44.4% | |
| 44.44% | 18 | 6.4 | 837 | 11,795 | 42.9% | 45.5% | |
| 50.00% | 18 | 5.8 | 754 | 12,373 | 28.6% | 63.6% | |
| 76.47% | 17 | 6.9 | 1,021 | 14,296 | 80.0% | 75.0% | |
| 29.41% | 17 | 6.9 | 829 | 11,897 | 37.5% | 22.2% | |
| 41.18% | 17 | 6.0 | 862 | 15,191 | 60.0% | 33.3% | |
| 43.75% | 16 | 6.0 | 838 | 11,773 | 62.5% | 25.0% | |
| 56.25% | 16 | 6.6 | 907 | 11,527 | 57.1% | 55.6% | |
| 37.50% | 16 | 5.4 | 659 | 13,208 | 16.7% | 50.0% | |
| 68.75% | 16 | 6.7 | 937 | 13,925 | 83.3% | 60.0% | |
| 53.33% | 15 | 5.9 | 686 | 11,419 | 37.5% | 71.4% | |
| 73.33% | 15 | 6.4 | 851 | 12,621 | 77.8% | 66.7% | |
| 50.00% | 14 | 5.7 | 851 | 11,114 | 16.7% | 75.0% | |
| 42.86% | 14 | 4.3 | 645 | 12,051 | 14.3% | 71.4% | |
| 53.85% | 13 | 3.3 | 885 | 14,162 | 75.0% | 44.4% | |
| 53.85% | 13 | 5.7 | 1,055 | 13,762 | 50.0% | 55.6% | |
| 58.33% | 12 | 5.6 | 562 | 10,027 | 57.1% | 60.0% | |
| 25.00% | 12 | 4.5 | 862 | 13,083 | 25.0% | 25.0% | |
| 50.00% | 12 | 6.3 | 784 | 13,328 | 33.3% | 66.7% | |
| 27.27% | 11 | 6.2 | 771 | 13,462 | 33.3% | 25.0% | |
| 63.64% | 11 | 6.3 | 874 | 15,826 | 66.7% | 62.5% | |
| 36.36% | 11 | 6.6 | 651 | 10,706 | 50.0% | 20.0% | |
| 45.45% | 11 | 5.5 | 919 | 12,629 | 50.0% | 40.0% | |
| 72.73% | 11 | 6.4 | 745 | 10,850 | 71.4% | 75.0% | |
| 45.45% | 11 | 6.0 | 1,064 | 14,508 | 40.0% | 50.0% | |
| 70.00% | 10 | 6.6 | 996 | 13,490 | 75.0% | 66.7% | |
| 40.00% | 10 | 6.8 | 876 | 13,216 | 33.3% | 50.0% | |
| 55.56% | 9 | 6.3 | 937 | 12,286 | 33.3% | 100.0% | |
| 44.44% | 9 | 6.2 | 1,077 | 15,702 | 100.0% | 28.6% | |
| 33.33% | 9 | 6.8 | 774 | 11,069 | 20.0% | 50.0% | |
| 25.00% | 8 | 5.5 | 693 | 10,378 | 25.0% | 25.0% | |
| 50.00% | 8 | 5.9 | 973 | 8,785 | 33.3% | 100.0% | |
| 37.50% | 8 | 1.9 | 834 | 14,727 | 33.3% | 40.0% | |
| 42.86% | 7 | 5.6 | 901 | 12,809 | 100.0% | 20.0% | |
| 0.00% | 7 | 6.6 | 558 | 10,700 | 0.0% | 0.0% | |
| 42.86% | 7 | 4.6 | 651 | 14,538 | 50.0% | 40.0% | |
| 71.43% | 7 | 6.1 | 682 | 13,126 | 75.0% | 66.7% | |
| 57.14% | 7 | 5.5 | 888 | 12,316 | 25.0% | 100.0% | |
| 57.14% | 7 | 5.4 | 895 | 12,100 | 50.0% | 66.7% | |
| 42.86% | 7 | 4.0 | 773 | 11,643 | 33.3% | 50.0% | |
| 57.14% | 7 | 2.5 | 1,313 | 15,576 | 25.0% | 100.0% | |
| 33.33% | 6 | 4.6 | 570 | 9,105 | 25.0% | 50.0% | |
| 66.67% | 6 | 5.9 | 1,089 | 15,493 | 50.0% | 75.0% | |
| 50.00% | 6 | 5.7 | 762 | 13,182 | 50.0% | 50.0% | |
| 50.00% | 6 | 1.9 | 891 | 14,832 | 100.0% | 40.0% | |
| 16.67% | 6 | 5.3 | 844 | 10,442 | 0.0% | 33.3% | |
| 0.00% | 6 | 5.9 | 795 | 10,724 | 0.0% | 0.0% | |
| 83.33% | 6 | 6.1 | 963 | 11,361 | 100.0% | 50.0% | |
| 50.00% | 6 | 6.3 | 804 | 13,574 | 100.0% | 40.0% | |
| 40.00% | 5 | 4.7 | 939 | 14,778 | 100.0% | 0.0% | |
| 60.00% | 5 | 1.7 | 1,195 | 17,648 | 0.0% | 75.0% | |
| 20.00% | 5 | 1.5 | 691 | 9,378 | 33.3% | 0.0% | |
| 60.00% | 5 | 5.3 | 1,100 | 15,380 | 100.0% | 50.0% | |
| 20.00% | 5 | 6.8 | 915 | 12,553 | 0.0% | 33.3% | |
| 40.00% | 5 | 6.5 | 1,021 | 17,603 | 0.0% | 40.0% | |
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Vayne vs Miss Fortune - Frequently Asked Questions
How does Vayne do against Miss Fortune in League of Legends?
Miss Fortune wins the Vayne vs Miss Fortune matchup with a 51.0% win rate compared to Vayne's 49.0%, a 2.0 percentage point difference. This data is based on 302 recent ranked games in patch 26.7.
How does Vayne do against Miss Fortune in the early game?
In the early game, Miss Fortune has the advantage against Vayne with a 52.5% win rate versus 47.5%. Miss Fortune players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Miss Fortune in the late game?
In the late game, Vayne takes over the Vayne vs Miss Fortune matchup with a 50.3% win rate compared to 49.7%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Miss Fortune matchup?
Miss Fortune wins the matchup against Vayne with a 51.0% win rate in League of Legends patch 26.7. The 2.0 percentage point advantage means Miss Fortune is slightly favored in this lane matchup based on 302 games analyzed.
What is the best Vayne build against Miss Fortune?
The best Vayne build against Miss Fortune includes optimized core items. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Miss Fortune?
The best Vayne runes against Miss Fortune use the Precision primary tree with Domination secondary. This rune setup achieves a 54.8% win rate in the Vayne vs Miss Fortune matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Miss Fortune?
No, Vayne struggles against Miss Fortune with only a 49.0% win rate. Miss Fortune has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Miss Fortune's lead.
How do I play Vayne against Miss Fortune?
When playing Vayne against Miss Fortune, play cautiously and avoid Miss Fortune's power spikes. Focus on safe farming — you outscale Miss Fortune in the late game. Use the matchup-specific build and runes above to optimize your chances.