
Zacvs Vayne
Zac vs Vayne is a decisive matchup in LoL patch 26.9. Vayne wins with a 71.4% win rate (+42.9%) over Zac based on 7 games. Vayne wins the early laning phase while Zac scales better into the late game. Below you'll find the best Zac build, runes, laning stats, and strategies for the Zac vs Vayne matchup.
Zac Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Zac performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Zac vs Vayne Matchup?

Zac vs Vayne Matchup Summary
The Zac vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Vayne wins with a 71.4% win rate compared to Zac's 28.6%, giving Vayne a 42.9 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Zac outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Zac reaches their power spikes, while Zac should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Zac leads by 1,385 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Zac players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Zac vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Zac, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Zac Build Against Vayne
Mercury's Treads is the optimal boots choice against Vayne, providing the mobility and stats Zac needs most in this matchup. The top-performing core items for Zac against Vayne are Hextech Rocketbelt, Thornmail and Sunfire Aegis. This combination gives Zac an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Zac vs Vayne matchup.
Early Game vs Late Game
Vayne dominates the early game (first 15 minutes) with a commanding 80.0% win rate — a 60.0 percentage point lead over Zac. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Late game (25+ minutes) is equally balanced, with Zac at 50.0% win rate — only 0.0 points ahead of Vayne. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.
The power dynamics shift as the game progresses — Vayne has the edge early, but Zac gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Zac Runes Against Vayne
The Domination and Resolve rune setup gives Zac the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Zac matchup data for League of Legends patch 26.9. The table below shows Zac's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Zac build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.23% | 65 | 1.2 | 573 | 11,915 | 42.9% | 54.0% | |
| 45.16% | 62 | 1.0 | 565 | 11,532 | 51.9% | 40.0% | |
| 49.12% | 57 | 1.0 | 597 | 12,081 | 68.2% | 37.1% | |
| 55.10% | 49 | 1.2 | 612 | 12,191 | 60.9% | 50.0% | |
| 58.33% | 48 | 0.9 | 600 | 12,697 | 50.0% | 62.5% | |
| 58.54% | 41 | 1.1 | 621 | 12,057 | 62.5% | 56.0% | |
| 56.10% | 41 | 1.0 | 562 | 10,891 | 42.1% | 68.2% | |
| 35.90% | 39 | 0.9 | 552 | 10,473 | 31.3% | 39.1% | |
| 43.59% | 39 | 1.1 | 672 | 11,240 | 38.1% | 50.0% | |
| 43.24% | 37 | 1.3 | 591 | 11,573 | 43.8% | 42.9% | |
| 54.05% | 37 | 1.1 | 630 | 11,678 | 55.6% | 52.6% | |
| 57.58% | 33 | 1.3 | 630 | 12,282 | 57.9% | 57.1% | |
| 65.63% | 32 | 1.1 | 590 | 11,795 | 57.1% | 72.2% | |
| 41.94% | 31 | 1.0 | 610 | 12,454 | 58.3% | 31.6% | |
| 54.84% | 31 | 1.4 | 597 | 11,734 | 58.8% | 50.0% | |
| 60.00% | 30 | 1.1 | 622 | 11,881 | 71.4% | 50.0% | |
| 58.62% | 29 | 1.2 | 626 | 12,877 | 60.0% | 57.9% | |
| 55.56% | 27 | 1.0 | 595 | 11,550 | 56.3% | 54.5% | |
| 68.00% | 25 | 1.0 | 646 | 13,070 | 75.0% | 64.7% | |
| 66.67% | 24 | 1.1 | 662 | 11,635 | 69.2% | 63.6% | |
| 33.33% | 24 | 1.0 | 579 | 11,529 | 18.2% | 46.1% | |
| 60.87% | 23 | 1.1 | 662 | 13,286 | 77.8% | 50.0% | |
| 43.48% | 23 | 1.1 | 633 | 10,554 | 45.5% | 41.7% | |
| 63.64% | 22 | 1.9 | 578 | 12,125 | 66.7% | 61.5% | |
| 54.55% | 22 | 1.1 | 522 | 10,873 | 30.8% | 88.9% | |
| 52.38% | 21 | 1.2 | 590 | 11,367 | 54.5% | 50.0% | |
| 70.00% | 20 | 3.5 | 893 | 10,903 | 66.7% | 71.4% | |
| 60.00% | 20 | 1.6 | 632 | 11,071 | 81.8% | 33.3% | |
| 45.00% | 20 | 1.3 | 521 | 10,227 | 45.5% | 44.4% | |
| 47.37% | 19 | 1.2 | 624 | 11,644 | 54.5% | 37.5% | |
| 61.11% | 18 | 0.9 | 624 | 11,811 | 77.8% | 44.4% | |
| 55.56% | 18 | 1.3 | 673 | 12,529 | 71.4% | 45.5% | |
| 56.25% | 16 | 0.9 | 606 | 11,371 | 60.0% | 54.5% | |
| 56.25% | 16 | 1.8 | 810 | 12,949 | 71.4% | 44.4% | |
| 40.00% | 15 | 1.9 | 572 | 10,459 | 33.3% | 50.0% | |
| 53.33% | 15 | 1.5 | 612 | 10,962 | 50.0% | 55.6% | |
| 57.14% | 14 | 1.9 | 684 | 12,227 | 57.1% | 57.1% | |
| 28.57% | 14 | 2.5 | 536 | 9,290 | 22.2% | 40.0% | |
| 76.92% | 13 | 1.2 | 786 | 14,887 | 85.7% | 66.7% | |
| 61.54% | 13 | 1.0 | 460 | 11,092 | 40.0% | 75.0% | |
| 69.23% | 13 | 3.3 | 608 | 11,631 | 85.7% | 50.0% | |
| 41.67% | 12 | 1.6 | 606 | 11,702 | 33.3% | 50.0% | |
| 50.00% | 12 | 4.6 | 661 | 11,025 | 57.1% | 40.0% | |
| 50.00% | 12 | 1.4 | 702 | 14,586 | 0.0% | 66.7% | |
| 54.55% | 11 | 3.1 | 644 | 11,639 | 60.0% | 50.0% | |
| 45.45% | 11 | 1.4 | 601 | 10,971 | 33.3% | 60.0% | |
| 50.00% | 10 | 2.4 | 544 | 11,254 | 33.3% | 57.1% | |
| 66.67% | 9 | 2.1 | 561 | 10,463 | 40.0% | 100.0% | |
| 77.78% | 9 | 5.3 | 824 | 12,650 | 100.0% | 60.0% | |
| 33.33% | 9 | 1.6 | 647 | 12,864 | 50.0% | 20.0% | |
| 66.67% | 9 | 1.2 | 708 | 11,962 | 50.0% | 80.0% | |
| 66.67% | 9 | 4.7 | 552 | 10,473 | 75.0% | 60.0% | |
| 100.00% | 9 | 2.2 | 660 | 12,722 | 100.0% | 100.0% | |
| 66.67% | 9 | 2.8 | 612 | 8,651 | 50.0% | 100.0% | |
| 25.00% | 8 | 1.1 | 548 | 10,544 | 25.0% | 25.0% | |
| 50.00% | 8 | 1.7 | 472 | 11,391 | 60.0% | 33.3% | |
| 62.50% | 8 | 1.5 | 688 | 12,414 | 100.0% | 50.0% | |
| 62.50% | 8 | 2.9 | 648 | 10,879 | 50.0% | 66.7% | |
| 62.50% | 8 | 4.1 | 767 | 11,898 | 80.0% | 33.3% | |
| 42.86% | 7 | 1.9 | 601 | 11,438 | 33.3% | 50.0% | |
| 28.57% | 7 | 2.9 | 378 | 6,702 | 20.0% | 50.0% | |
| 42.86% | 7 | 5.1 | 486 | 8,091 | 50.0% | 0.0% | |
| 28.57% | 7 | 3.2 | 785 | 11,973 | 0.0% | 50.0% | |
| 71.43% | 7 | 1.3 | 666 | 12,257 | 50.0% | 80.0% | |
| 66.67% | 6 | 1.9 | 615 | 11,744 | 50.0% | 100.0% | |
| 33.33% | 6 | 4.6 | 576 | 9,661 | 100.0% | 20.0% | |
| 50.00% | 6 | 5.8 | 679 | 11,032 | 50.0% | 50.0% | |
| 50.00% | 6 | 1.7 | 436 | 9,959 | 33.3% | 66.7% | |
| 83.33% | 6 | 7.4 | 800 | 11,050 | 100.0% | 0.0% | |
| 50.00% | 6 | 1.2 | 603 | 11,679 | 0.0% | 50.0% | |
| 66.67% | 6 | 1.0 | 581 | 13,065 | 100.0% | 60.0% | |
| 50.00% | 6 | 2.0 | 551 | 10,785 | 0.0% | 100.0% | |
| 66.67% | 6 | 1.3 | 809 | 14,585 | 100.0% | 50.0% | |
| 50.00% | 6 | 1.5 | 444 | 9,629 | 66.7% | 33.3% | |
| 60.00% | 5 | 6.7 | 754 | 10,792 | 66.7% | 50.0% | |
| 40.00% | 5 | 2.8 | 685 | 11,470 | 0.0% | 66.7% | |
| 20.00% | 5 | 1.9 | 437 | 9,089 | 0.0% | 50.0% | |
| 40.00% | 5 | 1.4 | 519 | 7,811 | 50.0% | 33.3% | |
| 60.00% | 5 | 4.8 | 650 | 11,276 | 50.0% | 66.7% | |
| 40.00% | 5 | 1.9 | 601 | 7,484 | 66.7% | 0.0% | |
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Zac vs Vayne - Frequently Asked Questions
How does Zac do against Vayne in League of Legends?
Vayne wins the Zac vs Vayne matchup with a 71.4% win rate compared to Zac's 28.6%, a 42.9 percentage point difference. This data is based on 7 recent ranked games in patch 26.9.
How does Zac do against Vayne in the early game?
In the early game, Vayne has the advantage against Zac with a 80.0% win rate versus 20.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Zac do against Vayne in the late game?
In the late game, Zac takes over the Zac vs Vayne matchup with a 50.0% win rate compared to 50.0%. Zac scales better into team fights and objective contests after 25 minutes.
Who wins the Zac vs Vayne matchup?
Vayne wins the matchup against Zac with a 71.4% win rate in League of Legends patch 26.9. The 42.9 percentage point advantage means Vayne is significantly favored in this lane matchup based on 7 games analyzed.
What is the best Zac build against Vayne?
The best Zac build against Vayne includes Hextech Rocketbelt, Thornmail, Sunfire Aegis with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Zac runes against Vayne?
The best Zac runes against Vayne use the Domination primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Zac vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Zac counter Vayne?
No, Zac struggles against Vayne with only a 28.6% win rate. Vayne has the advantage in this matchup. Zac players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Zac against Vayne?
When playing Zac against Vayne, play cautiously and avoid Vayne's power spikes. Focus on safe farming — you outscale Vayne in the late game. Use the matchup-specific build and runes above to optimize your chances.