Vayne - League of Legends Champion
Win Rate
48.8%
Pick Rate
7.2%

Vaynevs Zac

DMarksmanAssassin
Patch26.9
Matches514,344
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 10, 2026
MethodologyData Methodology

Vayne vs Zac is a decisive matchup in LoL patch 26.9. Vayne wins with a 71.4% win rate (+42.9%) over Zac based on 7 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Zac matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zac - 71.4% win rateZac(71.4%)
Vayne - 71.4% win rate in this matchup
Vayne
71.4% WR
VS
Zac vs Vayne matchup - 28.6% win rate
Zac
28.6% WR

Who Wins the Vayne vs Zac Matchup?

Vayne wins the Vayne vs Zac matchup
Winner
Vayne
Matches: 7
71.4%
Win Rate
28.6%
3.6
CS / min
2.9
711
DMG / min
378
7,631
Gold / game
6,702
233
Heal / min
1,154
427
DMG Mitigated / min
892
0.5
CC / min
1.0
80.0%
Early Game WR
20.0%
50.0%
Late Game WR
50.0%

Vayne vs Zac Matchup Summary

The Vayne vs Zac matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Vayne wins with a 71.4% win rate compared to Zac's 28.6%, giving Vayne a 42.9 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Zac players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Zac leads by 1,385 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Zac and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Zac away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Zac Laning Phase Breakdown

Vayne wins the laning phase against Zac in League of Legends

Vayne is favored during the laning phase against Zac, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
3.6Vayne
2.9Zac
Vayne edges out Zac by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
711Vayne
378Zac
Vayne heavily out-damages Zac by 333 DMG/min, dominating both short trades and all-in fights. Zac should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
7,631Vayne
6,702Zac
Vayne generates a commanding 929 more gold per game than Zac. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Zac should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.5Vayne
1.0Zac
Zac provides 0.5 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zac coordinate with their jungler and control the pace of skirmishes.
Sustain
660Vayne
2,045Zac
Zac vastly out-sustains Vayne, healing and mitigating 1,385 more damage per minute. This massive durability gap means Zac can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Zac

Berserker's Greaves is the optimal boots choice against Zac, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Zac are Kraken Slayer, Blade of The Ruined King and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Zac matchup.

Early Game vs Late Game

Early Game
Vayne
80.0%
+60.0% advantage
Vayne early game win rateVayne80.0%
Zac early game win rateZac20.0%
Late Game
Vayne
50.0%
+0.0% advantage
Vayne late game win rateVayne50.0%
Zac late game win rateZac50.0%

Vayne dominates the early game (first 15 minutes) with a commanding 80.0% win rate — a 60.0 percentage point lead over Zac. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Vayne at 50.0% win rate — only 0.0 points ahead of Zac. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Zac players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Zac

Precision rune tree - Vayne primary runes vs ZacPrecision
Press the Attack - best Vayne rune vs ZacTriumph - best Vayne rune vs ZacLegend: Alacrity - best Vayne rune vs ZacCoup de Grace - best Vayne rune vs Zac
Domination rune tree - Vayne secondary runes vs ZacDomination
Taste of Blood - best Vayne rune vs ZacTreasure Hunter - best Vayne rune vs Zac
100.0% WR

Running Precision primary with Domination secondary allows Vayne to press their advantage against Zac, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.9. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.9
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.84%4596.379112,83243.4%49.8%
48.25%4566.484913,46951.9%45.8%
48.01%4526.180612,91741.5%53.2%
46.51%3725.981012,61848.1%45.2%
53.50%3576.183912,56250.6%56.5%
47.98%3466.281212,99848.8%47.3%
49.84%3116.585213,16353.7%46.3%
57.91%2796.388813,57154.0%61.0%
54.78%1576.495012,34862.7%50.0%
52.45%1436.088112,71046.9%57.0%
44.85%1366.185413,03844.6%45.0%
45.38%1196.185713,45032.1%56.1%
54.31%1166.080212,86152.1%55.9%
52.68%1125.974512,58653.7%51.7%
51.82%1106.379213,21849.1%54.4%
40.40%996.061710,82734.7%46.0%
52.58%976.192513,75350.0%54.1%
50.54%936.079612,64941.0%57.4%
47.19%896.083012,39839.1%55.8%
42.86%846.379012,58542.9%42.9%
50.00%826.784513,66148.8%51.3%
62.67%756.283513,62668.0%60.0%
54.67%756.380011,19754.3%55.0%
52.17%696.487413,28754.5%50.0%
47.76%676.593211,21844.1%51.5%
55.38%656.298014,76761.1%53.2%
40.32%626.06149,67632.3%48.4%
38.33%606.199811,41442.9%34.4%
62.50%566.61,12613,48862.5%62.5%
43.64%556.51,20411,35240.7%46.4%
54.00%507.095611,17353.1%55.6%
55.10%496.391611,83857.1%53.6%
40.82%496.486112,99447.6%35.7%
50.00%486.096413,37343.8%53.1%
55.32%475.886311,03236.4%72.0%
48.89%455.788912,76842.9%51.6%
53.33%455.992915,08718.2%64.7%
61.36%446.296813,73352.9%66.7%
46.51%435.675410,92943.8%48.1%
54.76%426.71,07413,16961.1%50.0%
58.54%416.074711,55257.1%60.0%
46.15%396.281610,97258.8%36.4%
44.74%385.986012,49753.3%39.1%
47.37%386.081011,12043.8%50.0%
55.26%386.981612,61850.0%58.3%
48.65%376.388911,26447.6%50.0%
48.65%376.076212,23846.1%50.0%
45.71%357.193912,29246.7%45.0%
48.57%356.583212,24553.9%45.5%
47.06%346.097911,73740.0%52.6%
54.55%336.290411,57050.0%60.0%
59.38%326.31,00915,15058.3%60.0%
40.63%326.498513,38972.7%23.8%
67.74%316.071211,10558.3%73.7%
54.84%316.197911,28461.5%50.0%
64.52%316.288512,32292.9%41.2%
51.61%316.084511,77827.3%65.0%
43.33%306.389811,99261.5%29.4%
50.00%306.191212,57546.1%52.9%
46.15%266.379212,03040.0%50.0%
46.15%266.296511,86063.6%33.3%
60.00%255.693713,80085.7%50.0%
64.00%256.393516,36350.0%66.7%
66.67%246.391212,89050.0%72.2%
41.67%246.574811,15838.5%45.5%
43.48%235.972911,46542.9%44.4%
52.17%236.394511,04862.5%28.6%
43.48%235.568010,95045.5%41.7%
54.55%226.498612,63950.0%58.3%
40.91%225.772111,02650.0%33.3%
54.55%225.883114,683100.0%47.4%
45.45%226.276310,83640.0%50.0%
28.57%215.568610,35520.0%36.4%
33.33%214.286811,65916.7%40.0%
42.86%215.876011,69237.5%46.1%
28.57%216.389810,27328.6%28.6%
40.00%206.31,04314,31822.2%54.5%
50.00%206.683513,03260.0%46.7%
55.00%206.180914,43525.0%62.5%
52.63%196.683511,79940.0%66.7%
52.63%193.481312,59871.4%41.7%
44.44%185.887812,03342.9%45.5%
29.41%176.371212,14814.3%40.0%
37.50%165.71,00015,08328.6%44.4%
50.00%166.381712,61014.3%77.8%
73.33%156.392413,34466.7%77.8%
46.67%154.164210,36250.0%44.4%
64.29%146.078715,1130.0%75.0%
61.54%135.859711,55871.4%50.0%
38.46%136.081311,51660.0%25.0%
50.00%126.285013,47680.0%28.6%
25.00%125.397315,6650.0%30.0%
58.33%122.386813,12640.0%71.4%
41.67%126.593812,36050.0%37.5%
45.45%116.082710,69640.0%50.0%
40.00%105.397013,9450.0%57.1%
70.00%106.987511,11266.7%75.0%
33.33%95.575811,20960.0%0.0%
77.78%96.886811,80280.0%75.0%
22.22%96.370711,31933.3%0.0%
44.44%96.996212,8300.0%80.0%
37.50%86.478811,77166.7%20.0%
37.50%85.71,12913,8970.0%37.5%
50.00%82.965211,26150.0%50.0%
62.50%86.672913,28275.0%50.0%
71.43%73.67117,63180.0%50.0%
14.29%76.264511,35925.0%0.0%
42.86%75.889813,17333.3%50.0%
42.86%75.680910,67650.0%33.3%
14.29%71.561111,07833.3%0.0%
42.86%75.675114,3530.0%50.0%
33.33%67.387312,8800.0%50.0%
66.67%65.869912,59150.0%75.0%
66.67%63.064411,6530.0%80.0%
50.00%65.81,22214,13150.0%50.0%
50.00%66.597113,3620.0%75.0%
66.67%65.465411,3530.0%100.0%
50.00%65.91,01913,5620.0%60.0%
40.00%52.655213,111100.0%25.0%
60.00%53.280114,245100.0%50.0%
20.00%53.560111,8000.0%25.0%
20.00%51.593212,52025.0%0.0%
60.00%51.979111,244100.0%33.3%

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Vayne vs Zac - Frequently Asked Questions

How does Vayne do against Zac in League of Legends?

Vayne wins the Vayne vs Zac matchup with a 71.4% win rate compared to Zac's 28.6%, a 42.9 percentage point difference. This data is based on 7 recent ranked games in patch 26.9.

How does Vayne do against Zac in the early game?

In the early game, Vayne has the advantage against Zac with a 80.0% win rate versus 20.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Zac in the late game?

In the late game, Vayne takes over the Vayne vs Zac matchup with a 50.0% win rate compared to 50.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Zac matchup?

Vayne wins the matchup against Zac with a 71.4% win rate in League of Legends patch 26.9. The 42.9 percentage point advantage means Vayne is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Vayne build against Zac?

The best Vayne build against Zac includes Kraken Slayer, Blade of The Ruined King, Experimental Hexplate with Berserker's Greaves. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Zac?

The best Vayne runes against Zac use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Zac matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Zac?

Yes, Vayne has a favorable matchup against Zac with a 71.4% win rate. Vayne strongly counters Zac in lane based on current patch 26.9 data.

How do I play Vayne against Zac?

When playing Vayne against Zac, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.