Entropy•Power

Is Entropy good in Slay the Spire 2?

In Slay the Spire 2, Entropy is a rare power from the Colorless card pool. Its effect: At the start of your turn, Transform cards in your Hand. Right now it’s a premium pick that sits at S tier — one of the better cards you can add to a deck this run.

Over 19 tracked runs its win rate sits at 40.0%, 21.1% ahead of the 18.9% all-deck baseline. It sees niche play, included in only 0.5% of eligible runs. Within Necrobinder runs it’s drafted 0.6% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.2 copies on average.

Its standout pairing so far is Afterimage, which lifts its win rate by +13.8% when the two share a deck. On the relic side, Lucky Fysh is its standout companion, worth a +17.1% win-rate swing alongside it. It costs 1 energy, gets upgraded 39.1% of the time, and tends to be picked up near floor 21.

Of the runs that drafted it, 6 ended in victory against 9 deaths and 4 abandons. Its most common run-ender is Entomancer Elite, finishing 10.5% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Entropy fits a Colorless deck.

Best Cards to Pair with Entropy

Entropy’s strongest card pairings so far are Afterimage (+13.8%), Ultimate Defend (+10.0%), and Byrd Swoop (+6.2%), each shown with the win-rate lift it adds.

Afterimage+13.8%3 runsUltimate Defend+10.0%6 runsByrd Swoop+6.2%3 runsBlade Dance+6.2%3 runsAccuracy+6.2%3 runsEscape Plan+6.2%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Entropy Win Rate by Class

Of the 5 classes that draft Entropy, it performs best with Necrobinder (50.0%), Defect (50.0%), and Silent (40.0%).

The Necrobinder50.0%5 runsThe Defect50.0%4 runsThe Silent40.0%6 runsThe Ironclad33.3%3 runsThe Regent0.0%1 runs

Best Relics for Entropy

The relics that swing Entropy’s win rate the most are Lucky Fysh (+17.1%), Bag of Marbles (+13.8%), and Whetstone (+13.8%), with each lift shown.

Lucky Fysh+17.1%4 runsBag of Marbles+13.8%3 runsWhetstone+13.8%3 runsVajra+13.3%5 runsLord's Parasol+13.3%5 runsScroll Boxes+10.0%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Entropy Card Details

A 1-energy rare power, Entropy is upgraded 39.1% of the time and tends to enter the deck around floor 21.

At the start of your turn, Transform cards in your Hand.

What Ends Runs with Entropy

Runs holding Entropy end most often against Entomancer Elite (10.5%), Queen Boss (10.5%), and The Kin Boss (10.5%) — the share of its runs each accounts for is shown.

• Entomancer Elite10.5% of runs
• Queen Boss10.5% of runs
• The Kin Boss10.5% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.