Nasus - League of Legends Champion
Win Rate
47.9%
Pick Rate
2.7%

Nasusvs Seraphine

FFighterTank
Patch26.10
Matches900,877
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Nasus vs Seraphine is a decisive matchup in LoL patch 26.10. Seraphine wins with a 60.0% win rate (+20.0%) over Nasus based on 5 games. Seraphine wins the early laning phase while Nasus scales better into the late game. Below you'll find the best Nasus build, runes, laning stats, and strategies for the Nasus vs Seraphine matchup.

Nasus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nasus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 40.0% win rateSeraphine(40.0%)
Nasus - 40.0% win rate in this matchup
Nasus
40.0% WR
VS
Seraphine vs Nasus matchup - 60.0% win rate
Seraphine
60.0% WR

Who Wins the Nasus vs Seraphine Matchup?

Seraphine wins the Nasus vs Seraphine matchup
Winner
Seraphine
Matches: 5
40.0%
Win Rate
60.0%
3.2
CS / min
2.6
478
DMG / min
549
9,994
Gold / game
9,053
400
Heal / min
332
965
DMG Mitigated / min
318
0.8
CC / min
1.1
0.0%
Early Game WR
100.0%
66.7%
Late Game WR
33.3%

Nasus vs Seraphine Matchup Summary

The Nasus vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Seraphine wins with a 60.0% win rate compared to Nasus's 40.0%, giving Seraphine a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Nasus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Nasus reaches their power spikes, while Nasus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nasus leads by 715 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Nasus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nasus vs Seraphine Laning Phase Breakdown

Nasus wins the laning phase against Seraphine in League of Legends

Nasus is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Nasus holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
3.2Nasus
2.6Seraphine
Nasus edges out Seraphine by 0.6 CS per minute — a moderate farming advantage that adds up to roughly 10 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Nasus.
Damage
478Nasus
549Seraphine
Seraphine deals 70 more champion damage per minute than Nasus. While noticeable in extended trades, this gap can be offset by Nasus choosing favorable fight windows, such as engaging when Seraphine's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
9,994Nasus
9,053Seraphine
Nasus generates a commanding 941 more gold per game than Seraphine. This substantial economic advantage means Nasus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.8Nasus
1.1Seraphine
Seraphine provides 0.3 seconds more crowd control per minute than Nasus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
1,365Nasus
650Seraphine
Nasus vastly out-sustains Seraphine, healing and mitigating 715 more damage per minute. This massive durability gap means Nasus can absorb significant punishment and remain in lane while Seraphine is forced to recall. Building grievous wounds early is essential for Seraphine, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nasus Build Against Seraphine

Crimson Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Nasus needs most in this matchup. The top-performing core items for Nasus against Seraphine are Serylda's Grudge, Frozen Heart and Trinity Force. This combination gives Nasus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nasus vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
100.0%
+100.0% advantage
Nasus early game win rateNasus0.0%
Seraphine early game win rateSeraphine100.0%
Late Game
Nasus
66.7%
+33.3% advantage
Nasus late game win rateNasus66.7%
Seraphine late game win rateSeraphine33.3%

Seraphine dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Nasus. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Nasus is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Seraphine. Extended games heavily favor Nasus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Seraphine must aggressively press their early advantage and close out the game before Nasus reaches their scaling breakpoints. If Nasus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Nasus Runes Against Seraphine

Sorcery rune tree - Nasus primary runes vs SeraphineSorcery
Summon Aery - best Nasus rune vs SeraphineManaflow Band - best Nasus rune vs SeraphineTranscendence - best Nasus rune vs SeraphineScorch - best Nasus rune vs Seraphine
Inspiration rune tree - Nasus secondary runes vs SeraphineInspiration
Approach Velocity - best Nasus rune vs SeraphineBiscuit Delivery - best Nasus rune vs Seraphine
100.0% WR

The Sorcery and Inspiration rune setup gives Nasus the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Nasus matchup data for League of Legends patch 26.10. The table below shows Nasus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nasus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nasus matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
38.87%2836.375111,45035.5%41.4%
47.46%2366.159711,71853.7%43.3%
46.99%1835.675611,36449.3%45.5%
50.34%1475.878511,63146.8%52.9%
47.24%1276.674011,82935.2%56.2%
59.65%1146.767511,24958.5%60.7%
54.00%1006.868512,26758.7%50.0%
49.47%955.779911,56946.7%50.8%
51.06%946.384510,68943.8%58.7%
52.13%945.876911,14936.6%64.2%
48.91%926.273011,39448.6%49.1%
40.45%896.41,20711,78541.7%39.6%
34.88%866.975911,85345.2%29.1%
54.12%856.076211,20059.5%48.8%
54.76%845.569811,30451.3%57.8%
48.15%815.577111,41646.9%49.0%
42.31%786.378511,10540.5%43.9%
40.00%756.282911,93734.4%44.2%
54.93%716.181911,64060.7%51.2%
44.93%693.171112,69142.3%46.5%
41.79%675.964310,88933.3%50.0%
51.52%665.990011,02864.0%43.9%
51.52%663.778013,15662.5%45.2%
43.08%656.583912,66155.0%37.8%
53.97%636.159111,75261.9%50.0%
51.61%624.193612,44546.1%55.6%
45.16%625.672610,82832.1%55.9%
36.07%616.477611,78229.6%41.2%
54.10%616.673011,62252.2%55.3%
54.24%596.376810,68851.4%58.3%
50.00%582.775713,04247.8%51.4%
49.12%576.177211,61665.4%35.5%
42.11%576.181211,47840.7%43.3%
57.69%526.480512,65759.3%56.0%
51.92%526.272011,55355.0%50.0%
53.06%495.668610,61156.5%50.0%
55.10%496.477711,98948.1%63.6%
48.94%476.179712,04440.9%56.0%
53.33%452.280512,76452.9%53.6%
38.64%446.293911,28953.9%16.7%
55.81%435.963011,63463.2%50.0%
51.22%416.076410,65052.6%50.0%
57.50%406.465112,19953.3%60.0%
48.72%391.871011,64531.3%60.9%
46.15%392.270311,80240.0%52.6%
57.89%385.569410,31947.6%70.6%
55.56%365.680212,13846.7%61.9%
57.14%352.270212,27256.3%57.9%
51.43%354.876912,94783.3%34.8%
58.82%346.663911,86062.5%55.6%
63.64%336.888011,77275.0%52.9%
50.00%322.073913,06036.4%57.1%
43.75%325.870611,81130.8%52.6%
60.00%306.880212,71861.5%58.8%
36.67%306.479410,78120.0%53.3%
58.62%293.487013,67346.1%68.8%
55.56%275.175811,87563.6%50.0%
30.77%265.861610,04133.3%28.6%
65.38%261.678714,66557.1%68.4%
52.00%252.975813,88533.3%62.5%
64.00%254.586711,30757.1%72.7%
40.00%255.670210,79841.7%38.5%
52.00%256.572611,27753.9%50.0%
44.00%256.381011,37236.4%50.0%
40.00%256.462410,36920.0%53.3%
54.17%247.078913,88344.4%60.0%
56.52%235.468111,44855.6%57.1%
54.55%226.575311,16235.7%87.5%
36.36%221.777513,81137.5%35.7%
75.00%201.577412,016100.0%58.3%
50.00%202.467611,18130.0%70.0%
16.67%184.765911,70714.3%18.2%
38.89%184.967112,04540.0%38.5%
38.89%186.672310,92254.5%14.3%
56.25%166.780211,55566.7%50.0%
46.67%156.069311,00957.1%37.5%
46.67%154.773911,87775.0%36.4%
53.33%152.070910,82162.5%42.9%
57.14%146.770011,23750.0%66.7%
50.00%142.688014,24040.0%55.6%
61.54%132.175012,69571.4%50.0%
69.23%134.199412,883100.0%55.6%
46.15%136.064312,38075.0%33.3%
38.46%133.661310,24628.6%50.0%
53.85%135.61,02012,38280.0%37.5%
36.36%116.21,02112,62120.0%50.0%
45.45%114.17159,35842.9%50.0%
30.00%101.157211,36425.0%33.3%
40.00%106.979811,02640.0%40.0%
40.00%106.481512,47850.0%33.3%
50.00%103.367713,932100.0%37.5%
40.00%106.555110,07125.0%50.0%
40.00%103.982112,68420.0%60.0%
77.78%92.263312,639100.0%66.7%
55.56%91.293613,54180.0%25.0%
55.56%91.479814,43333.3%66.7%
44.44%95.981712,286100.0%0.0%
37.50%85.979611,6590.0%50.0%
25.00%86.864410,97925.0%25.0%
50.00%86.949910,99950.0%50.0%
42.86%76.760910,36050.0%33.3%
85.71%71.977811,99275.0%100.0%
57.14%77.282212,42966.7%50.0%
42.86%75.877512,76933.3%50.0%
66.67%65.54017,731100.0%33.3%
50.00%62.970311,20175.0%0.0%
50.00%65.558811,13250.0%50.0%
50.00%66.550314,005100.0%40.0%
66.67%66.28629,620100.0%50.0%
33.33%65.665010,71425.0%50.0%
0.00%62.145310,3420.0%0.0%
40.00%55.264011,7930.0%50.0%
40.00%52.962310,16450.0%33.3%
60.00%57.266913,56833.3%100.0%
40.00%53.24789,9940.0%66.7%
40.00%55.95399,49425.0%100.0%
80.00%55.388212,77550.0%100.0%
60.00%51.54539,783100.0%50.0%

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Nasus vs Seraphine - Frequently Asked Questions

How does Nasus do against Seraphine in League of Legends?

Seraphine wins the Nasus vs Seraphine matchup with a 60.0% win rate compared to Nasus's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Nasus do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Nasus with a 100.0% win rate versus 0.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nasus do against Seraphine in the late game?

In the late game, Nasus takes over the Nasus vs Seraphine matchup with a 66.7% win rate compared to 33.3%. Nasus scales better into team fights and objective contests after 25 minutes.

Who wins the Nasus vs Seraphine matchup?

Seraphine wins the matchup against Nasus with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Nasus build against Seraphine?

The best Nasus build against Seraphine includes Serylda's Grudge, Frozen Heart, Trinity Force with Crimson Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Nasus runes against Seraphine?

The best Nasus runes against Seraphine use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Nasus vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Nasus counter Seraphine?

No, Nasus struggles against Seraphine with only a 40.0% win rate. Seraphine has the advantage in this matchup. Nasus players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Nasus against Seraphine?

When playing Nasus against Seraphine, play cautiously and avoid Seraphine's power spikes. Focus on safe farming — you outscale Seraphine in the late game. Use the matchup-specific build and runes above to optimize your chances.