- Win Rate
- 48.3%
- Pick Rate
- 3.3%
- Ban Rate
- 5.4%
Vayne Synergies & Best Teammates
- Patch
- 26.20
- Games
- 4,273
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Oct 14, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Who Vayne wins with in Patch 26.20: every teammate in every role, measured against what both champions win on their own, so a strong pair is real synergy and not two strong champions.
- Best jungler
- Nocturne58.9% · 90 games
- Best top laner
- Jax61.7% · 81 games
Vayne Synergies - Patch 26.20
113 teammate pairings measuredVayne (Bot) wins most with Jax as top laner (61.7%, +10.9 over expected) and Nocturne as jungler (58.9%, +10.3). The weakest pairing is Nautilus as support at 39.7%, 9.4 points below expected. The most common lane partner is Lulu, in 5.8% of Vayne's games.
Best supports for Vayne
| Teammate | Win Rate | Synergy | Games |
|---|---|---|---|
 Pantheon | 59.7% | +12.3 | 62 |
 Milio | 56.8% | +5.8 | 139 |
 Lulu | 51.9% | +1.6 | 183 |
 Braum | 54.0% | +4.1 | 63 |
 Alistar | 55.0% | +4.2 | 60 |
 Janna | 50.0% | +0.8 | 94 |
Weakest pairings
Best junglers for Vayne
| Teammate | Win Rate | Synergy | Games |
|---|---|---|---|
 Nocturne | 58.9% | +10.3 | 90 |
 Qiyana | 55.0% | +10.5 | 60 |
 Rammus | 63.5% | +10.3 | 52 |
 Hecarim | 55.1% | +9.5 | 49 |
 Kayn | 50.8% | +1.5 | 187 |
 Sejuani | 60.5% | +7.9 | 43 |
Weakest pairings
Strongest and weakest Vayne pairings
Jax · top laner- Nocturne · jungler
Garen · top laner
Yone · mid laner
Darius · top laner
Nautilus · support
Best junglers for Vayne
No teammate in this role clearly lifts the win rate yet.
Weakest pairings
| Teammate | Win Rate | Synergy | Games |
|---|---|---|---|
 Master Yi | 37.2% | −8.9 | 43 |
Best mid laners with Vayne
No teammate in this role clearly lifts the win rate yet.
Weakest pairings
Synergy is the win rate with that teammate minus the win rate the two champions would be expected to reach together from their own win rates in their roles (log5). Lists are ranked by the low end of each synergy's 95% range, so a small sample cannot lead a list on luck alone.
Vayne Team Synergy Checker
Pick your teammates
Pick your teammates to see how each one moves Vayne's Bot win rate, and an estimate for the whole team.
An estimate: it adds each pairing's measured synergy on the odds scale and assumes the pairings are independent. Real teams also depend on the enemy draft and the players.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Vayne Synergies FAQ - Patch 26.20
Who is the best jungler for Vayne?
Nocturne. Vayne (Bot) wins 58.9% of 90 ranked games with Nocturne as jungler, 10.3 points above what the two champions win separately. Also strong: Qiyana, Kayn.
Which champions does Vayne synergize with?
This patch, Vayne (Bot) gets the biggest lift from Jax (top laner, 61.7%), Nocturne (jungler, 58.9%), Garen (top laner, 58.9%).
Which teammates are bad with Vayne?
Vayne (Bot) does worst next to Nautilus (support, 39.7%), Darius (top laner, 38.5%), Yone (mid laner, 44.2%) — each below what the two champions win on their own.
How is synergy calculated?
From ranked solo and flex games this patch: the win rate when both champions are on the same team, minus the win rate expected from each champion's own win rate in its role. A positive number means the pair wins more together than their individual strength explains. Pairings need at least 40 games to be listed.