Vayne, League of Legends champion
Win Rate
49.5%
Pick Rate
3.2%
Ban Rate
6.5%

VayneSynergies & Best Teammates

Vayne C TierMarksmanAssassin
Patch26.19
Games2,903
LaneAll Lanes
TierAll Tiers
Last UpdatedOct 2, 2026 UTC
MethodologyData Methodology

Who Vayne wins with in Patch 26.19: every teammate in every role, measured against what both champions win on their own, so a strong pair is real synergy and not two strong champions.

Best mid laner
Lissandra58.2% · 91 games
Best top laner
Yasuo62.5% · 88 games

Vayne Synergies - Patch 26.19

147 teammate pairings measured

Vayne (Bot) wins most with Yasuo as top laner (62.5%, +14.0 over expected) and Gnar as top laner (61.4%, +13.8). The weakest pairing is Yasuo as mid laner at 44.1%, 5.7 points below expected. The most common lane partner is Lulu, in 6.5% of Vayne's games.

Best supports for Vayne

TeammateWin RateSynergyGames
Yuumi54.0%+6.4124
Lux52.8%+3.5248
Swain53.0%+5.3115
Seraphine53.1%+2.1228
Lulu50.8%+1.0313
Karma52.3%+3.8128

Weakest pairings

TeammateWin RateSynergyGames
Thresh44.4%−5.5277
Sona41.4%−10.087
Blitzcrank43.8%−5.0137

Best junglers for Vayne

TeammateWin RateSynergyGames
Nunu & Willump65.3%+16.849
Naafiri56.9%+10.958
Xin Zhao60.4%+11.348
Graves54.3%+5.6116
Briar54.4%+3.3171
Master Yi51.9%+2.0237

Weakest pairings

TeammateWin RateSynergyGames
Bel'Veth44.0%−8.575
Warwick47.1%−3.8172
Kayn48.2%−1.2330

Best mid laners with Vayne

TeammateWin RateSynergyGames
Xerath66.7%+16.666
Aurelion Sol65.6%+14.861
Lissandra58.2%+8.791
Locke53.4%+5.7148
Akali53.0%+5.9134
Fizz56.7%+4.8164

Weakest pairings

TeammateWin RateSynergyGames
Yasuo44.1%−5.7279
Katarina42.9%−5.4133
Zoe38.3%−9.360

Best top laners with Vayne

TeammateWin RateSynergyGames
Yasuo62.5%+14.088
Gnar61.4%+13.883
Garen54.1%+3.5183
Nasus53.3%+3.4165
Teemo53.1%+2.0213
Jax51.8%+3.3137

Weakest pairings

TeammateWin RateSynergyGames
K'Sante33.3%−12.160
Tryndamere43.1%−7.4109
Renekton46.2%−4.8117

Strongest and weakest Vayne pairings

  • Yasuo · top laner+14.0
  • Gnar · top laner+13.8
  • Lissandra · mid laner+8.7
  • Sona · support−10.0
  • Thresh · support−5.5
  • Yasuo · mid laner−5.7

Vayne (Top) wins most with Kayn as jungler (52.4%, +3.6 over expected) and Miss Fortune as ADC (52.9%, +3.8). The weakest pairing is Jinx as ADC at 47.8%, 3.4 points below expected.

Best junglers for Vayne

TeammateWin RateSynergyGames
Wukong65.1%+13.843
Kayn52.4%+3.5105
Amumu57.5%+6.740
Lee Sin48.9%+2.545
Nocturne48.9%+0.247

Weakest pairings

TeammateWin RateSynergyGames
Shaco40.4%−6.747
Cho'Gath45.8%−5.248
Warwick47.1%−3.351

Best supports for Vayne

TeammateWin RateSynergyGames
Janna59.6%+8.757
Nami53.2%+2.362
Morgana52.5%+2.361
Pyke51.2%+4.543

Weakest pairings

TeammateWin RateSynergyGames
Lulu37.0%−12.254
Blitzcrank38.3%−9.947
Nautilus40.5%−6.774

Best mid laners with Vayne

TeammateWin RateSynergyGames
Yasuo54.4%+5.279
Vladimir57.1%+6.442
Malzahar52.9%+3.368
Akali52.3%+5.844
Fizz55.2%+3.858
Ahri52.8%+3.053

Weakest pairings

TeammateWin RateSynergyGames
Veigar42.1%−7.657
Yone45.2%−5.273
Sylas43.5%−4.646

Best ADCs for Vayne

TeammateWin RateSynergyGames
Aphelios58.3%+10.148
Ezreal51.4%+7.172
Yunara57.4%+7.961
Miss Fortune52.9%+3.885
Caitlyn49.3%+0.9146
Ashe51.1%+2.988

Weakest pairings

TeammateWin RateSynergyGames
Jinx47.8%−3.4115
Jhin45.9%−3.0122
Kai'Sa43.6%−4.878

Strongest and weakest Vayne pairings

  • Kayn · jungler+3.5
  • Miss Fortune · ADC+3.8
  • Caitlyn · ADC+0.9
  • Lux · support−1.4
  • Jhin · ADC−3.0
  • Jinx · ADC−3.4

Synergy is the win rate with that teammate minus the win rate the two champions would be expected to reach together from their own win rates in their roles (log5). Lists are ranked by the low end of each synergy's 95% range, so a small sample cannot lead a list on luck alone.

Vayne Team Synergy Checker

Pick your teammates

Pick your teammates to see how each one moves Vayne's Bot win rate, and an estimate for the whole team.

Estimated win rate49.2%Pick at least one teammate

An estimate: it adds each pairing's measured synergy on the odds scale and assumes the pairings are independent. Real teams also depend on the enemy draft and the players.

Compare every bot lane duo →

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Vayne Synergies FAQ - Patch 26.19

Who is the best mid laner for Vayne?

Lissandra. Vayne (Bot) wins 58.2% of 91 ranked games with Lissandra as mid laner, 8.7 points above what the two champions win separately. Also strong: Xerath, Aurelion Sol.

Which champions does Vayne synergize with?

This patch, Vayne (Bot) gets the biggest lift from Yasuo (top laner, 62.5%), Gnar (top laner, 61.4%), Lissandra (mid laner, 58.2%).

Which teammates are bad with Vayne?

Vayne (Bot) does worst next to Yasuo (mid laner, 44.1%), Thresh (support, 44.4%), Sona (support, 41.4%) — each below what the two champions win on their own.

How is synergy calculated?

From ranked solo and flex games this patch: the win rate when both champions are on the same team, minus the win rate expected from each champion's own win rate in its role. A positive number means the pair wins more together than their individual strength explains. Pairings need at least 40 games to be listed.