Vex - League of Legends Champion
Win Rate
50.2%
Pick Rate
2.0%

Vexvs Seraphine

BMage
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Vex vs Seraphine is a decisive matchup in LoL patch 26.14. Seraphine wins with a 69.2% win rate (+38.5%) over Vex based on 13 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Vex build, runes, laning stats, and strategies for the Vex vs Seraphine matchup.

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Vex Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vex performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vex - 30.8% win rate in this matchup
Vex
30.8% WR
VS
Seraphine vs Vex matchup - 69.2% win rate
Seraphine
69.2% WR

Who Wins the Vex vs Seraphine Matchup?

Seraphine wins the Vex vs Seraphine matchup
Winner
Seraphine
Matches: 13
30.8%
Win Rate
69.2%
4.3
CS / min
4.3
628
DMG / min
566
9,445
Gold / game
10,349
82
Heal / min
172
379
DMG Mitigated / min
284
1.0
CC / min
1.0
33.3%
Early Game WR
66.7%
28.6%
Late Game WR
71.4%

Vex vs Seraphine Matchup Summary

The Vex vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Seraphine wins with a 69.2% win rate compared to Vex's 30.8%, giving Seraphine a 38.5 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vex players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Vex leads by 62 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Vex players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vex vs Seraphine Laning Phase Breakdown

Vex wins the laning phase against Seraphine in League of Legends

Vex is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Vex holds advantages in farming, damage and sustain, making them the stronger laner in this matchup.

Farming
4.3Vex
4.3Seraphine
Vex and Seraphine farm at nearly identical rates in this matchup, with only a 0.0 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
628Vex
566Seraphine
Vex deals 62 more champion damage per minute than Seraphine. While noticeable in extended trades, this gap can be offset by Seraphine choosing favorable fight windows, such as engaging when Vex's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
9,445Vex
10,349Seraphine
Seraphine generates a commanding 904 more gold per game than Vex. This substantial economic advantage means Seraphine consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vex should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.0Vex
1.0Seraphine
Both Vex and Seraphine provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
461Vex
455Seraphine
Vex and Seraphine have comparable sustain profiles, with only 6 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Vex Build Against Seraphine

Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Vex needs most in this matchup. The top-performing core items for Vex against Seraphine are Luden's Echo, Stormsurge and Shadowflame. This combination gives Vex an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vex vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
66.7%
+33.3% advantage
Vex early game win rateVex33.3%
Seraphine early game win rateSeraphine66.7%
Late Game
Seraphine
71.4%
+42.9% advantage
Vex late game win rateVex28.6%
Seraphine late game win rateSeraphine71.4%

Seraphine dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Vex. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 71.4% win rate — 42.9 points above Vex. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vex players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vex Runes Against Seraphine

Domination rune tree - Vex primary runes vs SeraphineDomination
Electrocute - best Vex rune vs SeraphineTaste of Blood - best Vex rune vs SeraphineGrisly Mementos - best Vex rune vs SeraphineUltimate Hunter - best Vex rune vs Seraphine
Inspiration rune tree - Vex secondary runes vs SeraphineInspiration
Biscuit Delivery - best Vex rune vs SeraphineCosmic Insight - best Vex rune vs Seraphine
50.0% WR

The Domination and Inspiration rune setup gives Vex the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vex matchup data for League of Legends patch 26.14. The table below shows Vex's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vex build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vex matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.76%1275.993511,44346.1%57.3%
50.93%1085.897111,57056.1%47.8%
42.71%965.887811,22438.2%45.2%
43.82%896.284611,12051.4%38.5%
60.24%835.899110,50069.2%52.3%
51.25%805.991810,52753.9%48.8%
48.48%665.61,07612,40542.9%51.1%
56.92%655.483611,91671.4%52.9%
50.79%635.899311,69757.7%46.0%
45.16%625.61,04710,50442.3%47.2%
45.90%616.01,01111,16060.9%36.8%
52.83%536.01,03912,14247.6%56.3%
47.92%485.883211,33350.0%46.9%
53.19%475.890810,43254.2%52.2%
51.11%455.787311,54780.0%36.7%
62.22%456.299012,28860.0%63.3%
41.86%436.499711,33160.0%32.1%
53.66%415.991411,21750.0%56.5%
55.56%365.787210,84166.7%47.6%
55.88%345.988211,50253.9%57.1%
57.58%335.780011,17333.3%71.4%
60.00%305.91,03310,25664.3%56.3%
62.50%245.697811,51066.7%60.0%
47.83%235.882511,58457.1%43.8%
39.13%235.782011,31937.5%40.0%
52.38%215.888311,28037.5%61.5%
45.00%206.188111,94542.9%46.1%
44.44%185.990711,36828.6%54.5%
61.11%185.691110,98980.0%37.5%
52.94%176.195811,53055.6%50.0%
52.94%175.697611,18257.1%50.0%
50.00%166.11,07311,89975.0%41.7%
53.33%156.41,07711,34860.0%50.0%
46.67%156.695911,97442.9%50.0%
53.33%156.19459,33460.0%40.0%
50.00%145.37589,51542.9%57.1%
64.29%145.490410,73550.0%70.0%
57.14%145.284510,33066.7%50.0%
38.46%135.494510,70260.0%25.0%
30.77%134.36289,44533.3%28.6%
30.77%135.990011,29425.0%33.3%
83.33%126.51,14812,05885.7%80.0%
63.64%115.51,11412,87380.0%50.0%
55.56%94.771510,58366.7%50.0%
44.44%95.91,00010,37340.0%50.0%
50.00%85.78319,36040.0%66.7%
37.50%85.799212,65050.0%33.3%
57.14%75.51,12813,27166.7%50.0%
28.57%74.897513,0560.0%28.6%
71.43%76.389811,317100.0%50.0%
57.14%75.998711,95166.7%50.0%
42.86%75.185411,79466.7%25.0%
33.33%66.29749,6130.0%66.7%
33.33%66.399511,0440.0%40.0%
33.33%64.07629,93450.0%25.0%
66.67%65.51,0309,45750.0%75.0%
50.00%65.895511,17233.3%66.7%
50.00%66.393513,027100.0%25.0%
50.00%65.91,08015,1890.0%50.0%
40.00%54.76358,8680.0%66.7%
40.00%56.01,25611,402100.0%0.0%
80.00%55.499213,115100.0%66.7%
60.00%55.71,19311,24650.0%66.7%
60.00%55.01,07511,52950.0%66.7%
60.00%56.392314,7780.0%75.0%
80.00%54.896713,121100.0%66.7%

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Vex vs Seraphine - Frequently Asked Questions

How does Vex do against Seraphine in League of Legends?

Seraphine wins the Vex vs Seraphine matchup with a 69.2% win rate compared to Vex's 30.8%, a 38.5 percentage point difference. This data is based on 13 recent ranked games in patch 26.14.

How does Vex do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Vex with a 66.7% win rate versus 33.3%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vex do against Seraphine in the late game?

In the late game, Seraphine takes over the Vex vs Seraphine matchup with a 71.4% win rate compared to 28.6%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Vex vs Seraphine matchup?

Seraphine wins the matchup against Vex with a 69.2% win rate in League of Legends patch 26.14. The 38.5 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 13 games analyzed.

What is the best Vex build against Seraphine?

The best Vex build against Seraphine includes Luden's Echo, Stormsurge, Shadowflame with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vex runes against Seraphine?

The best Vex runes against Seraphine use the Domination primary tree with Inspiration secondary. This rune setup achieves a 50.0% win rate in the Vex vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Vex counter Seraphine?

No, Vex struggles against Seraphine with only a 30.8% win rate. Seraphine has the advantage in this matchup. Vex players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Vex against Seraphine?

When playing Vex against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.