Vex - League of Legends Champion
Win Rate
48.3%
Pick Rate
2.0%

Vexvs Seraphine

FMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Vex vs Seraphine is a decisive matchup in LoL patch 26.11. Seraphine wins with a 61.5% win rate (+23.1%) over Vex based on 13 games. Vex wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Vex build, runes, laning stats, and strategies for the Vex vs Seraphine matchup.

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Vex Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vex performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vex - 38.5% win rate in this matchup
Vex
38.5% WR
VS
Seraphine vs Vex matchup - 61.5% win rate
Seraphine
61.5% WR

Who Wins the Vex vs Seraphine Matchup?

Seraphine wins the Vex vs Seraphine matchup
Winner
Seraphine
Matches: 13
38.5%
Win Rate
61.5%
4.0
CS / min
3.1
781
DMG / min
594
10,844
Gold / game
9,468
105
Heal / min
209
453
DMG Mitigated / min
372
1.2
CC / min
1.2
57.1%
Early Game WR
42.9%
16.7%
Late Game WR
83.3%

Vex vs Seraphine Matchup Summary

The Vex vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Seraphine wins with a 61.5% win rate compared to Vex's 38.5%, giving Seraphine a 23.1 percentage point advantage. Game phase dynamics play a critical role here: Vex controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vex needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Vex leads by 187 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Vex players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vex vs Seraphine Laning Phase Breakdown

Vex wins the laning phase against Seraphine in League of Legends

Vex is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Vex holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
4.0Vex
3.1Seraphine
Vex significantly out-farms Seraphine by 0.9 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Vex a major gold advantage and earlier item completions. Seraphine players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
781Vex
594Seraphine
Vex heavily out-damages Seraphine by 187 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vex's sustained damage advantage take over.
Economy
10,844Vex
9,468Seraphine
Vex generates a commanding 1,376 more gold per game than Seraphine. This substantial economic advantage means Vex consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.2Vex
1.2Seraphine
Both Vex and Seraphine provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
558Vex
581Seraphine
Vex and Seraphine have comparable sustain profiles, with only 24 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Vex Build Against Seraphine

Spellslinger's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Vex needs most in this matchup. The top-performing core items for Vex against Seraphine are Luden's Echo, Shadowflame and Zhonya's Hourglass. This combination gives Vex an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vex vs Seraphine matchup.

Early Game vs Late Game

Early Game
Vex
57.1%
+14.3% advantage
Vex early game win rateVex57.1%
Seraphine early game win rateSeraphine42.9%
Late Game
Seraphine
83.3%
+66.7% advantage
Vex late game win rateVex16.7%
Seraphine late game win rateSeraphine83.3%

Vex dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Seraphine. This lopsided early game means Vex can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 83.3% win rate — 66.7 points above Vex. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Vex must aggressively press their early advantage and close out the game before Seraphine reaches their scaling breakpoints. If Seraphine survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Vex Runes Against Seraphine

Domination rune tree - Vex primary runes vs SeraphineDomination
Electrocute - best Vex rune vs SeraphineTaste of Blood - best Vex rune vs SeraphineGrisly Mementos - best Vex rune vs SeraphineUltimate Hunter - best Vex rune vs Seraphine
Sorcery rune tree - Vex secondary runes vs SeraphineSorcery
Manaflow Band - best Vex rune vs SeraphineTranscendence - best Vex rune vs Seraphine
45.5% WR

The Domination and Sorcery rune setup gives Vex the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vex matchup data for League of Legends patch 26.11. The table below shows Vex's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vex build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vex matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.95%1646.390410,88348.1%45.9%
52.83%1596.088611,35347.7%56.4%
46.27%1346.086911,78548.2%44.9%
46.83%1265.989911,56148.3%45.5%
53.60%1256.092810,95353.9%53.3%
51.26%1196.098311,23561.4%41.9%
41.12%1075.891912,36554.5%35.1%
41.35%1045.682011,04840.8%41.8%
46.15%916.296011,70534.2%54.7%
50.00%866.184111,12955.6%46.0%
56.47%856.089612,63448.3%60.7%
46.67%756.01,00911,67059.3%39.6%
56.16%735.897811,24354.3%57.9%
43.28%675.987312,41244.0%42.9%
55.56%636.095912,43058.3%53.9%
47.46%596.294612,37454.2%42.9%
44.07%596.597412,23245.5%43.2%
53.45%585.91,07612,24440.9%61.1%
49.12%575.584410,96556.5%44.1%
46.00%505.977710,72756.0%36.0%
58.00%505.885310,81654.2%61.5%
64.00%506.294011,97860.9%66.7%
50.00%446.293811,39372.2%34.6%
41.86%436.184911,33438.1%45.5%
51.16%435.984712,18358.8%46.1%
57.50%405.595812,39372.7%51.7%
60.53%386.21,03313,01162.5%59.1%
50.00%366.289610,30660.0%37.5%
50.00%366.294012,37768.8%35.0%
55.88%346.092011,81653.9%57.1%
48.48%336.11,00411,12150.0%47.1%
50.00%326.61,07311,90450.0%50.0%
54.84%316.098513,02040.0%61.9%
44.83%296.599612,04263.6%33.3%
55.17%296.199213,73166.7%50.0%
65.52%296.293211,07873.3%57.1%
50.00%286.295911,36350.0%50.0%
50.00%224.876810,85050.0%50.0%
47.62%216.094611,21342.9%50.0%
47.62%216.381110,57853.9%37.5%
52.63%196.388510,32661.5%33.3%
57.89%196.198712,18587.5%36.4%
50.00%186.191413,49175.0%42.9%
60.00%156.399312,06740.0%70.0%
66.67%155.47909,29860.0%80.0%
35.71%145.669510,79616.7%50.0%
38.46%134.078110,84457.1%16.7%
58.33%125.385811,56550.0%66.7%
63.64%116.297113,08250.0%66.7%
40.00%106.39779,77242.9%33.3%
40.00%105.699012,33350.0%37.5%
20.00%106.588912,23825.0%16.7%
60.00%105.797712,75466.7%57.1%
50.00%105.189913,27533.3%57.1%
70.00%105.595613,22360.0%80.0%
20.00%105.78219,50133.3%0.0%
55.56%96.47069,88060.0%50.0%
66.67%96.48239,20680.0%50.0%
50.00%85.588712,89660.0%33.3%
37.50%82.595610,65150.0%25.0%
25.00%85.686911,8080.0%33.3%
62.50%85.98698,35166.7%50.0%
62.50%85.41,25611,27666.7%60.0%
62.50%85.083613,177100.0%50.0%
71.43%74.473710,107100.0%60.0%
42.86%76.61,11513,628100.0%20.0%
57.14%75.81,34513,00550.0%66.7%
66.67%66.190413,4270.0%80.0%
33.33%65.485912,2570.0%50.0%
100.00%55.21,03215,077100.0%100.0%
20.00%52.264710,4350.0%33.3%
60.00%53.581111,19266.7%50.0%
60.00%51.970111,13033.3%100.0%
40.00%56.47224,47425.0%100.0%
40.00%56.56457,92425.0%100.0%
40.00%54.768311,125100.0%0.0%

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Vex vs Seraphine - Frequently Asked Questions

How does Vex do against Seraphine in League of Legends?

Seraphine wins the Vex vs Seraphine matchup with a 61.5% win rate compared to Vex's 38.5%, a 23.1 percentage point difference. This data is based on 13 recent ranked games in patch 26.11.

How does Vex do against Seraphine in the early game?

In the early game, Vex has the advantage against Seraphine with a 57.1% win rate versus 42.9%. Vex players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vex do against Seraphine in the late game?

In the late game, Seraphine takes over the Vex vs Seraphine matchup with a 83.3% win rate compared to 16.7%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Vex vs Seraphine matchup?

Seraphine wins the matchup against Vex with a 61.5% win rate in League of Legends patch 26.11. The 23.1 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 13 games analyzed.

What is the best Vex build against Seraphine?

The best Vex build against Seraphine includes Luden's Echo, Shadowflame, Zhonya's Hourglass with Spellslinger's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Vex runes against Seraphine?

The best Vex runes against Seraphine use the Domination primary tree with Sorcery secondary. This rune setup achieves a 45.5% win rate in the Vex vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Vex counter Seraphine?

No, Vex struggles against Seraphine with only a 38.5% win rate. Seraphine has the advantage in this matchup. Vex players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Vex against Seraphine?

When playing Vex against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.