Vex - League of Legends Champion
Win Rate
50.5%
Pick Rate
2.4%

Vexvs Lissandra

BMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 20, 2026
MethodologyData Methodology

Vex vs Lissandra is a decisive matchup in LoL patch 26.7. Lissandra wins with a 53.6% win rate (+7.1%) over Vex based on 28 games. Lissandra wins the early laning phase while Vex scales better into the late game. Below you'll find the best Vex build, runes, laning stats, and strategies for the Vex vs Lissandra matchup.

Vex Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vex performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 46.4% win rateLissandra(46.4%)
Vex - 46.4% win rate in this matchup
Vex
46.4% WR
VS
Lissandra vs Vex matchup - 53.6% win rate
Lissandra
53.6% WR

Who Wins the Vex vs Lissandra Matchup?

Lissandra wins the Vex vs Lissandra matchup
Winner
Lissandra
Matches: 28
46.4%
Win Rate
53.6%
6.1
CS / min
6.9
922
DMG / min
834
10,285
Gold / game
10,912
86
Heal / min
160
477
DMG Mitigated / min
396
1.1
CC / min
1.6
37.5%
Early Game WR
62.5%
58.3%
Late Game WR
41.7%

Vex vs Lissandra Matchup Summary

The Vex vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 28 recent matches analyzed, Lissandra wins with a 53.6% win rate compared to Vex's 46.4%, giving Lissandra a 7.1 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Vex outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Vex reaches their power spikes, while Vex should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Vex players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vex vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Vex in League of Legends

Lissandra is favored during the laning phase against Vex, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.1Vex
6.9Lissandra
Lissandra edges out Vex by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
922Vex
834Lissandra
Vex heavily out-damages Lissandra by 87 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vex's sustained damage advantage take over.
Economy
10,285Vex
10,912Lissandra
Lissandra earns 627 more gold per game than Vex, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
1.1Vex
1.6Lissandra
Lissandra provides 0.5 seconds more crowd control per minute than Vex, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
563Vex
557Lissandra
Vex and Lissandra have comparable sustain profiles, with only 7 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Vex Build Against Lissandra

Spellslinger's Shoes is the optimal boots choice against Lissandra, providing the mobility and stats Vex needs most in this matchup. The top-performing core items for Vex against Lissandra are Luden's Echo, Shadowflame and Zhonya's Hourglass. This combination gives Vex an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 6 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vex vs Lissandra matchup.

Early Game vs Late Game

Early Game
Lissandra
62.5%
+25.0% advantage
Vex early game win rateVex37.5%
Lissandra early game win rateLissandra62.5%
Late Game
Vex
58.3%
+16.7% advantage
Vex late game win rateVex58.3%
Lissandra late game win rateLissandra41.7%

Lissandra dominates the early game (first 15 minutes) with a commanding 62.5% win rate — a 25.0 percentage point lead over Vex. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vex is far superior in the late game (25+ minutes), boasting a 58.3% win rate — 16.7 points above Lissandra. Extended games heavily favor Vex, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Vex reaches their scaling breakpoints. If Vex survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Vex Runes Against Lissandra

Domination rune tree - Vex primary runes vs LissandraDomination
Dark Harvest - best Vex rune vs LissandraTaste of Blood - best Vex rune vs LissandraGrisly Mementos - best Vex rune vs LissandraUltimate Hunter - best Vex rune vs Lissandra
Sorcery rune tree - Vex secondary runes vs LissandraSorcery
Transcendence - best Vex rune vs LissandraManaflow Band - best Vex rune vs Lissandra
100.0% WR

The Domination and Sorcery rune setup gives Vex the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vex matchup data for League of Legends patch 26.7. The table below shows Vex's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vex build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vex matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
54.43%1586.390711,97953.3%55.4%
49.25%1346.492311,72936.2%59.2%
41.90%1056.087211,38939.5%43.5%
53.19%946.093311,40259.0%49.1%
56.67%905.484912,08554.8%57.6%
55.06%896.31,01711,59753.5%56.5%
50.00%806.196811,63247.2%52.3%
51.90%796.383212,02154.5%50.0%
39.19%745.782611,78731.0%44.4%
47.95%736.190411,44742.5%54.5%
61.19%675.993611,93664.3%59.0%
43.94%665.774410,82350.0%39.5%
55.74%616.285311,36558.1%53.3%
66.04%535.81,02812,43468.4%64.7%
50.00%506.381311,93143.5%55.6%
38.78%496.389411,28337.0%40.9%
50.00%486.079810,90155.6%42.9%
56.25%486.390012,82657.1%55.6%
54.35%466.01,04012,83166.7%48.4%
57.14%426.583911,14057.9%56.5%
50.00%426.181411,52250.0%50.0%
35.71%425.988610,60044.0%23.5%
48.72%396.595211,27445.5%52.9%
63.16%386.282710,98356.3%68.2%
56.76%375.983811,24456.3%57.1%
48.65%376.297412,49564.7%35.0%
41.67%365.587211,53537.5%45.0%
44.44%365.782111,49741.2%47.4%
61.76%345.998513,28775.0%57.7%
64.52%315.81,02312,08257.1%70.6%
50.00%306.398511,76853.9%47.1%
46.43%286.192210,28537.5%58.3%
37.04%276.098310,63235.3%40.0%
33.33%246.693011,16042.9%20.0%
52.17%236.362510,44060.0%46.1%
50.00%226.61,03413,49450.0%50.0%
55.00%206.093311,74687.5%33.3%
31.58%195.597312,41266.7%25.0%
55.56%186.485810,93085.7%36.4%
38.89%185.48099,55640.0%37.5%
46.67%155.082410,20944.4%50.0%
42.86%146.094310,48157.1%28.6%
53.85%135.080711,92040.0%62.5%
54.55%117.31,08312,23940.0%66.7%
10.00%106.193211,44716.7%0.0%
70.00%106.184211,04166.7%75.0%
55.56%96.377311,25675.0%40.0%
66.67%96.391211,18480.0%50.0%
55.56%95.71,03911,31725.0%80.0%
55.56%94.387411,74950.0%57.1%
37.50%86.489010,75566.7%20.0%
50.00%85.51,16712,60566.7%40.0%
25.00%85.91,01513,3060.0%33.3%
62.50%85.795511,64250.0%75.0%
62.50%81.96989,52233.3%80.0%
57.14%75.793612,0090.0%80.0%
42.86%75.61,02412,38266.7%25.0%
42.86%76.195112,3240.0%75.0%
28.57%72.25828,9940.0%40.0%
28.57%75.567010,59150.0%20.0%
83.33%61.773410,32066.7%100.0%
50.00%66.01,09210,93950.0%50.0%
83.33%65.591911,65675.0%100.0%
50.00%63.95689,55250.0%50.0%
50.00%64.595611,949100.0%40.0%
33.33%65.81,07812,4390.0%50.0%
0.00%64.462510,3030.0%0.0%
40.00%55.578510,32433.3%50.0%
40.00%52.57899,74766.7%0.0%
40.00%56.41,11514,54250.0%33.3%
60.00%56.01,12311,634100.0%33.3%
40.00%51.95187,85125.0%100.0%
80.00%55.91,07711,31066.7%100.0%
60.00%52.285911,65150.0%66.7%
60.00%55.592011,565100.0%33.3%
60.00%56.31,25614,3880.0%100.0%
0.00%55.31,01813,5090.0%0.0%
20.00%52.591210,0630.0%33.3%
20.00%55.885610,30050.0%0.0%

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Vex vs Lissandra - Frequently Asked Questions

How does Vex do against Lissandra in League of Legends?

Lissandra wins the Vex vs Lissandra matchup with a 53.6% win rate compared to Vex's 46.4%, a 7.1 percentage point difference. This data is based on 28 recent ranked games in patch 26.7.

How does Vex do against Lissandra in the early game?

In the early game, Lissandra has the advantage against Vex with a 62.5% win rate versus 37.5%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vex do against Lissandra in the late game?

In the late game, Vex takes over the Vex vs Lissandra matchup with a 58.3% win rate compared to 41.7%. Vex scales better into team fights and objective contests after 25 minutes.

Who wins the Vex vs Lissandra matchup?

Lissandra wins the matchup against Vex with a 53.6% win rate in League of Legends patch 26.7. The 7.1 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 28 games analyzed.

What is the best Vex build against Lissandra?

The best Vex build against Lissandra includes Luden's Echo, Shadowflame, Zhonya's Hourglass with Spellslinger's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vex runes against Lissandra?

The best Vex runes against Lissandra use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Vex vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Vex counter Lissandra?

No, Vex struggles against Lissandra with only a 46.4% win rate. Lissandra has the advantage in this matchup. Vex players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.

How do I play Vex against Lissandra?

When playing Vex against Lissandra, play cautiously and avoid Lissandra's power spikes. Focus on safe farming — you outscale Lissandra in the late game. Use the matchup-specific build and runes above to optimize your chances.