
Vexvs Annie
Vex vs Annie is a decisive matchup in LoL patch 26.17. Annie wins with a 61.5% win rate (+23.1%) over Vex based on 13 games. Vex wins the early laning phase while Annie scales better into the late game. Below you'll find the best Vex build, runes, laning stats, and strategies for the Vex vs Annie matchup.
Vex Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vex performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vex vs Annie Matchup?

Vex vs Annie Matchup Summary
The Vex vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Annie wins with a 61.5% win rate compared to Vex's 38.5%, giving Annie a 23.1 percentage point advantage. Game phase dynamics play a critical role here: Vex controls the early laning stage, but Annie outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vex needs to press advantages before Annie reaches their power spikes, while Annie should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Annie leads by 138 damage/min — a difference that heavily influences the outcome of trades and skirmishes. Annie has a strong advantage in this matchup. Vex players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Annie overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vex vs Annie Laning Phase Breakdown
Annie is favored during the laning phase against Vex, winning 3 out of 4 key stat categories. Annie holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Vex Build Against Annie
Not enough matchup-specific build data: only 3 of 8 Vex games against Annie carried a complete build, which is too few to recommend an item path from. Use Vex's standard build instead.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Vex and Annie, with Vex holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Annie is far superior in the late game (25+ minutes), boasting a 63.6% win rate — 27.3 points above Vex. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.
The power dynamics shift as the game progresses — Vex has the edge early, but Annie gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Vex Runes Against Annie
The Domination and Sorcery rune setup gives Vex the best tools to compete against Annie in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vex matchup data for League of Legends patch 26.17. The table below shows Vex's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vex build, runes, laning stats, and early vs late game analysis for that specific matchup.
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Vex vs Annie - Frequently Asked Questions
How does Vex do against Annie in League of Legends?
Annie wins the Vex vs Annie matchup with a 61.5% win rate compared to Vex's 38.5%, a 23.1 percentage point difference. This data is based on 13 recent ranked games in patch 26.17.
How does Vex do against Annie in the early game?
In the early game, Vex has the advantage against Annie with a 50.0% win rate versus 50.0%. Vex players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vex do against Annie in the late game?
In the late game, Annie takes over the Vex vs Annie matchup with a 63.6% win rate compared to 36.4%. Annie scales better into team fights and objective contests after 25 minutes.
Who wins the Vex vs Annie matchup?
Annie wins the matchup against Vex with a 61.5% win rate in League of Legends patch 26.17. The 23.1 percentage point advantage means Annie is significantly favored in this lane matchup based on 13 games analyzed.
What is the best Vex build against Annie?
There is not enough matchup-specific build data to recommend an item path for Vex against Annie yet. Use Vex's standard build for the current patch and adapt situational items to Annie.
What are the best Vex runes against Annie?
The best Vex runes against Annie use the Domination primary tree with Sorcery secondary. This rune setup achieves a 45.5% win rate in the Vex vs Annie matchup. See the full rune breakdown in the matchup comparison above.
Does Vex counter Annie?
No, Vex struggles against Annie with only a 38.5% win rate. Annie has the advantage in this matchup. Vex players should focus on safe farming and avoiding extended trades to minimize Annie's lead.
How do I play Vex against Annie?
When playing Vex against Annie, play cautiously and avoid Annie's power spikes. Look for jungle assistance and team-dependent plays since Annie has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.
