Vex - League of Legends Champion
Win Rate
52.3%
Pick Rate
2.2%
Ban Rate
4.7%

Vexvs Annie

SMage
Patch26.17
Games2,217
LaneAll Lanes
TierAll Tiers
Last UpdatedSep 11, 2026 UTC
MethodologyData Methodology

Vex vs Annie is a decisive matchup in LoL patch 26.17. Annie wins with a 61.5% win rate (+23.1%) over Vex based on 13 games. Vex wins the early laning phase while Annie scales better into the late game. Below you'll find the best Vex build, runes, laning stats, and strategies for the Vex vs Annie matchup.

Vex Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vex performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vex - 38.5% win rate in this matchup
Vex
38.5% WR
VS
Annie vs Vex matchup - 61.5% win rate
Annie
61.5% WR

Who Wins the Vex vs Annie Matchup?

Annie wins the Vex vs Annie matchup
Winner
Annie
Matches: 13
38.5%
Win Rate
61.5%
4.8
CS / min
5.3
806
DMG / min
944
12,028
Gold / game
13,317
86
Heal / min
86
446
DMG Mitigated / min
418
1.0
CC / min
0.9
50.0%
Early Game WR
50.0%
36.4%
Late Game WR
63.6%

Vex vs Annie Matchup Summary

The Vex vs Annie matchup is a decisive matchup in League of Legends ranked play. Based on 13 recent matches analyzed, Annie wins with a 61.5% win rate compared to Vex's 38.5%, giving Annie a 23.1 percentage point advantage. Game phase dynamics play a critical role here: Vex controls the early laning stage, but Annie outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vex needs to press advantages before Annie reaches their power spikes, while Annie should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Annie leads by 138 damage/min — a difference that heavily influences the outcome of trades and skirmishes. Annie has a strong advantage in this matchup. Vex players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Annie overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Very small sampleBased on 13 matches. This is far too small a sample to draw conclusions from — treat these numbers as provisional.

Vex vs Annie Laning Phase Breakdown

Annie wins the laning phase against Vex in League of Legends

Annie is favored during the laning phase against Vex, winning 3 out of 4 key stat categories. Annie holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
4.8Vex
5.3Annie
Annie edges out Vex by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Annie.
Damage
806Vex
944Annie
Annie heavily out-damages Vex by 138 DMG/min, dominating both short trades and all-in fights. Vex should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Annie's sustained damage advantage take over.
Economy
12,028Vex
13,317Annie
Annie generates a commanding 1,289 more gold per game than Vex. This substantial economic advantage means Annie consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Vex should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.0Vex
0.9Annie
Both Vex and Annie provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Healing
86Vex
86Annie
Vex and Annie heal similar amounts, only 0 HP/min apart. Anti-heal is not a priority in this matchup.
Durability
446Vex
418Annie
Vex and Annie mitigate a similar amount of damage (28/min apart), so neither side can rely on out-tanking the other.

Best Vex Build Against Annie

Not enough matchup-specific build data: only 3 of 8 Vex games against Annie carried a complete build, which is too few to recommend an item path from. Use Vex's standard build instead.

Early Game vs Late Game

Early Game
Vex
50.0%
+0.0% advantage
Vex early game win rateVex50.0%
Annie early game win rateAnnie50.0%
Late Game
Annie
63.6%
+27.3% advantage
Vex late game win rateVex36.4%
Annie late game win rateAnnie63.6%

The early game (first 15 minutes) is a toss-up between Vex and Annie, with Vex holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Annie is far superior in the late game (25+ minutes), boasting a 63.6% win rate — 27.3 points above Vex. Extended games heavily favor Annie, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Vex has the edge early, but Annie gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Vex Runes Against Annie

Domination rune tree - Vex primary runes vs AnnieDomination
Electrocute - best Vex rune vs AnnieTaste of Blood - best Vex rune vs AnnieGrisly Mementos - best Vex rune vs AnnieUltimate Hunter - best Vex rune vs Annie
Sorcery rune tree - Vex secondary runes vs AnnieSorcery
Manaflow Band - best Vex rune vs AnnieTranscendence - best Vex rune vs Annie
45.5% WR

The Domination and Sorcery rune setup gives Vex the best tools to compete against Annie in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vex matchup data for League of Legends patch 26.17. The table below shows Vex's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vex build, runes, laning stats, and early vs late game analysis for that specific matchup.

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Vex vs Annie - Frequently Asked Questions

How does Vex do against Annie in League of Legends?

Annie wins the Vex vs Annie matchup with a 61.5% win rate compared to Vex's 38.5%, a 23.1 percentage point difference. This data is based on 13 recent ranked games in patch 26.17.

How does Vex do against Annie in the early game?

In the early game, Vex has the advantage against Annie with a 50.0% win rate versus 50.0%. Vex players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vex do against Annie in the late game?

In the late game, Annie takes over the Vex vs Annie matchup with a 63.6% win rate compared to 36.4%. Annie scales better into team fights and objective contests after 25 minutes.

Who wins the Vex vs Annie matchup?

Annie wins the matchup against Vex with a 61.5% win rate in League of Legends patch 26.17. The 23.1 percentage point advantage means Annie is significantly favored in this lane matchup based on 13 games analyzed.

What is the best Vex build against Annie?

There is not enough matchup-specific build data to recommend an item path for Vex against Annie yet. Use Vex's standard build for the current patch and adapt situational items to Annie.

What are the best Vex runes against Annie?

The best Vex runes against Annie use the Domination primary tree with Sorcery secondary. This rune setup achieves a 45.5% win rate in the Vex vs Annie matchup. See the full rune breakdown in the matchup comparison above.

Does Vex counter Annie?

No, Vex struggles against Annie with only a 38.5% win rate. Annie has the advantage in this matchup. Vex players should focus on safe farming and avoiding extended trades to minimize Annie's lead.

How do I play Vex against Annie?

When playing Vex against Annie, play cautiously and avoid Annie's power spikes. Look for jungle assistance and team-dependent plays since Annie has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.