Guiding Star•Attack

Is Guiding Star good in Slay the Spire 2?

Guiding Star is a common Regent attack in Slay the Spire 2. In combat it resolves as: Deal 12 damage. Draw cards. It ranks among the strongest cards its class can draft right now, earning a spot at B tier in our Slay the Spire 2 card tier list.

Across 13 recorded runs, decks running it win 30.8% of the time, comfortably clear of the 12.6% average, by 18.1%. It’s a more selective pick, turning up in just 2.5% of decks that could run it. Regent players keep it in 7.8% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.1 times in the decks that take it.

It performs best next to Big Bang — together they post a +44.2% swing in win rate. It also has strong chemistry with the relic Anchor, which moves its win rate by +35.9%. At 1 energy, it’s upgraded in 20.0% of runs and usually joins the deck around floor 15.

Upgraded, it gains +1 Damage, +1 Cards, which is why so many decks invest a rest-site upgrade in it. That’s 4 wins, 9 deaths, and 0 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Louse Progenitor Normal, which closes out 15.4% of its appearances. Read on for Guiding Star’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Regent run.

Best Cards to Pair with Guiding Star

Ranked by win-rate lift, Guiding Star performs best alongside Big Bang (+44.2%), Devastate (+35.9%), and Parry (+35.9%).

Big Bang+44.2%4 runsDevastate+35.9%3 runsParry+35.9%3 runsGlitterstream+35.9%3 runsStardust+35.9%3 runsShining Strike+29.2%5 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Guiding Star Win Rate by Class

Guiding Star is drafted only by the Regent, where it holds a 30.8% win rate across 13 runs.

The Regentappears in 7.8% of its runs (13 tracked)

Best Relics for Guiding Star

Guiding Star pairs best with the relics Anchor (+35.9%), Bronze Scales (+35.9%), and Vajra (+29.2%), ranked by win-rate lift.

Anchor+35.9%3 runsBronze Scales+35.9%3 runsVajra+29.2%5 runsDivine Right+2.6%12 runsLarge Capsule+2.6%3 runsMercury Hourglass+2.6%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Guiding Star Card Details

Guiding Star is a common attack costing 1 energy; it’s upgraded in 20.0% of runs and usually picked up by floor 15.

Deal 12 damage. Draw cards.

Upgrade: +1 Damage, +1 Cards

What Ends Runs with Guiding Star

Guiding Star’s most common run-enders are Louse Progenitor Normal (15.4%) and Phrog Parasite Elite (15.4%).

• Louse Progenitor Normal15.4% of runs
• Phrog Parasite Elite15.4% of runs

See Also

Compare Guiding Star with the rest of the best Slay the Spire 2 cards, relics, and classes below.