Guiding Star•Attack

Is Guiding Star good in Slay the Spire 2?

Guiding Star is a common Regent attack in Slay the Spire 2. In combat it resolves as: Deal 12 damage. Draw cards. It currently underperforms most alternatives, sitting at F tier in our Slay the Spire 2 card rankings.

Across 119 recorded runs, decks running it win 20.0% of the time, comfortably clear of the 18.9% average, by 1.1%. It’s a more selective pick, turning up in just 3.1% of decks that could run it. Ironclad players keep it in 0.1% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.2 times in the decks that take it.

It performs best next to Mad Science — together they post a +21.2% swing in win rate. It also has strong chemistry with the relic Pear, which moves its win rate by +22.1%. At 1 energy, it’s upgraded in 20.7% of runs and usually joins the deck around floor 13.

Upgraded, it gains +1 Damage, +1 Cards, which is why so many decks invest a rest-site upgrade in it. That’s 19 wins, 76 deaths, and 24 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Phrog Parasite Elite, which closes out 4.2% of its appearances. Read on for Guiding Star’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Regent run.

Best Cards to Pair with Guiding Star

Ranked by win-rate lift, Guiding Star performs best alongside Mad Science (+21.2%), Dramatic Entrance (+18.5%), and The Smith (+17.5%).

Mad Science+21.2%7 runsDramatic Entrance+18.5%3 runsThe Smith+17.5%6 runsDying Star+16.7%23 runsNeutron Aegis+15.3%8 runsManifest Authority+15.0%15 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Guiding Star Win Rate by Class

Guiding Star is played across 2 classes, led by Ironclad (100.0%) and Regent (19.1%) by win rate.

The Ironclad100.0%1 runsThe Regent19.1%118 runs

Best Relics for Guiding Star

Guiding Star pairs best with the relics Pear (+22.1%), Candelabra (+21.2%), and Bag of Marbles (+20.9%), ranked by win-rate lift.

Pear+22.1%12 runsCandelabra+21.2%7 runsBag of Marbles+20.9%14 runsOrnamental Fan+18.9%9 runsJeweled Mask+18.5%3 runsVenerable Tea Set+17.5%15 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Guiding Star Card Details

Guiding Star is a common attack costing 1 energy; it’s upgraded in 20.7% of runs and usually picked up by floor 13.

Deal 12 damage. Draw cards.

Upgrade: +1 Damage, +1 Cards

What Ends Runs with Guiding Star

Guiding Star’s most common run-enders are Phrog Parasite Elite (4.2%), Decimillipede Elite (4.2%), and Entomancer Elite (3.4%).

• Phrog Parasite Elite4.2% of runs
• Decimillipede Elite4.2% of runs
• Entomancer Elite3.4% of runs
• Louse Progenitor Normal3.4% of runs
• Infested Prisms Elite3.4% of runs

See Also

Compare Guiding Star with the rest of the best Slay the Spire 2 cards, relics, and classes below.