Outbreak•Power

Is Outbreak good in Slay the Spire 2?

In Slay the Spire 2, Outbreak is an uncommon power from the Silent card pool. Its effect: Every you apply Poison, deal 11 damage to ALL enemies. The data flags it as a weaker pick, settling at F tier — usually one to pass on unless your deck specifically wants it.

Over 102 tracked runs its win rate sits at 20.6%, 1.7% ahead of the 18.9% all-deck baseline. It sees niche play, included in only 2.7% of eligible runs. Within Silent runs it’s drafted 10.4% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.1 copies on average.

Its standout pairing so far is Reflex, which lifts its win rate by +26.4% when the two share a deck. On the relic side, Lasting Candy is its standout companion, worth a +26.8% win-rate swing alongside it. It costs 1 energy, gets upgraded 27.4% of the time, and tends to be picked up near floor 17.

Of the runs that drafted it, 19 ended in victory against 73 deaths and 10 abandons. Its most common run-ender is Knowledge Demon Boss, finishing 7.8% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Outbreak fits a Silent deck.

Best Cards to Pair with Outbreak

Outbreak’s strongest card pairings so far are Reflex (+26.4%), Murder (+18.3%), and Shadowmeld (+17.3%), each shown with the win-rate lift it adds.

Reflex+26.4%5 runsMurder+18.3%3 runsShadowmeld+17.3%7 runsTactician+14.7%10 runsKnife Trap+13.1%5 runsDagger Throw+11.6%16 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Outbreak Win Rate by Class

Exclusive to the Silent, Outbreak posts a 20.6% win rate over 102 tracked runs.

The Silentappears in 10.4% of its runs (102 tracked)

Best Relics for Outbreak

The relics that swing Outbreak’s win rate the most are Lasting Candy (+26.8%), Nunchaku (+24.2%), and Sturdy Clamp (+20.9%), with each lift shown.

Lasting Candy+26.8%7 runsNunchaku+24.2%8 runsSturdy Clamp+20.9%7 runsCentennial Puzzle+20.6%12 runsFestive Popper+20.6%12 runsHorn Cleat+19.7%10 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Outbreak Card Details

A 1-energy uncommon power, Outbreak is upgraded 27.4% of the time and tends to enter the deck around floor 17.

Every you apply Poison, deal 11 damage to ALL enemies.

What Ends Runs with Outbreak

Runs holding Outbreak end most often against Knowledge Demon Boss (7.8%), Queen Boss (6.9%), and Entomancer Elite (6.9%) — the share of its runs each accounts for is shown.

• Knowledge Demon Boss7.8% of runs
• Queen Boss6.9% of runs
• Entomancer Elite6.9% of runs
• Kaiser Crab Boss5.9% of runs
• Test Subject Boss3.9% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.