Centennial PuzzleRelic
The first time you lose HP each combat, draw cards.
Is Centennial Puzzle good in Slay the Spire 2?
Centennial Puzzle is a common relic in Slay the Spire 2. While carried, it does the following: The first time you lose HP each combat, draw cards. It’s a reliable mid-tier relic, landing at C tier in our rankings.
Across 32 recorded runs, decks carrying it win 40.7% of the time, comfortably clear of the 12.6% average, by 28.1%. It’s a more situational relic, showing up in just 6.2% of runs. The class that gets the most out of it is the Silent, at a 50.0% win rate. Silent players hold onto it in 5.8% of their runs.
It combos especially well with High Five, worth a +59.3% win-rate swing together. Another strong card to run with it is Clumsy, worth +30.7% to its win rate. On average it’s acquired around floor 21 of a run. Its common rarity shapes how frequently you’ll run into it.
It has 11 run wins against 16 losses in our tracked data. When runs carrying it end, the most frequent culprit is Kaiser Crab Boss, which closes out 9.4% of them. Read on for Centennial Puzzle’s complete card, class, and threat breakdown before you decide to pick it up.
Centennial Puzzle Win Rate & Pick Rate
Centennial Puzzle’s 40.7% win rate clears the 12.6% all-run average by 28.1%, the gap charted below.
Run Outcomes with Centennial Puzzle
Centennial Puzzle has 11 wins and 21 losses over 32 tracked runs (34.4% won); abandoned runs count as losses.
- Wins 34.4%
- Losses 65.6%
Best Cards with Centennial Puzzle
Ranked by win-rate lift, the best cards to run with Centennial Puzzle are High Five (+59.3%), Clumsy (+30.7%), and Black Hole (+25.9%).
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Centennial Puzzle Details
Centennial Puzzle is a common relic carried in 6.2% of runs and usually picked up around floor 21.
The first time you lose HP each combat, draw cards.
What Ends Runs with Centennial Puzzle
Centennial Puzzle’s most common run-enders are Kaiser Crab Boss (9.4%), Waterfall Giant Boss (6.3%), and Queen Boss (6.3%).
- Kaiser Crab Boss9.4% of runs
- Waterfall Giant Boss6.3% of runs
- Queen Boss6.3% of runs
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Centennial Puzzle – Frequently Asked Questions
Is Centennial Puzzle good in Slay the Spire 2?
Across 32 tracked runs carrying it, Centennial Puzzle wins 40.7% of the time — +28.1% above the average run. Win rate reflects how often runs with the relic end in victory.
What does Centennial Puzzle do in Slay the Spire 2?
The first time you lose HP each combat, draw cards.
How rare is Centennial Puzzle in Slay the Spire 2?
Centennial Puzzle is a Common relic, picked up in 6.2% of tracked runs.
What is the best card to use with Centennial Puzzle?
In tracked runs, Centennial Puzzle has performed best alongside High Five, which lifts its win rate by +59.3% over 3 runs together.
Which class is Centennial Puzzle best in?
Centennial Puzzle has its highest win rate with The Silent (50.0%).
See Also
Compare Centennial Puzzle with the rest of the best Slay the Spire 2 relics, cards, and classes below.