Anivia - League of Legends Champion
Win Rate
48.7%
Pick Rate
2.1%

Aniviavs Kai'Sa

DMage
Patch26.10
Matches900,877
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Anivia vs Kai'Sa is a very close matchup in LoL patch 26.10. Anivia wins with a 50.0% win rate (+0.0%) over Kai'Sa based on 6 games. Anivia wins the early laning phase while Kai'Sa scales better into the late game. Below you'll find the best Anivia build, runes, laning stats, and strategies for the Anivia vs Kai'Sa matchup.

Anivia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Anivia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kai'Sa - 50.0% win rateKai'Sa(50.0%)
Anivia - 50.0% win rate in this matchup
Anivia
50.0% WR
VS
Kai'Sa vs Anivia matchup - 50.0% win rate
Kai'Sa
50.0% WR

Who Wins the Anivia vs Kai'Sa Matchup?

Anivia wins the Anivia vs Kai'Sa matchup
Winner
Anivia
Matches: 6
50.0%
Win Rate
50.0%
6.6
CS / min
6.5
840
DMG / min
1,019
13,576
Gold / game
13,257
228
Heal / min
164
535
DMG Mitigated / min
511
2.0
CC / min
0.1
66.7%
Early Game WR
33.3%
33.3%
Late Game WR
66.7%

Anivia vs Kai'Sa Matchup Summary

The Anivia vs Kai'Sa matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Anivia wins with a 50.0% win rate compared to Kai'Sa's 50.0%, giving Anivia a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Anivia controls the early laning stage, but Kai'Sa outscales as the game goes longer. The matchup shifts dramatically depending on game length — Anivia needs to press advantages before Kai'Sa reaches their power spikes, while Kai'Sa should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Anivia leads by 1.9s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Anivia has a statistical edge, but the margin is close enough that respecting Kai'Sa's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Anivia vs Kai'Sa Laning Phase Breakdown

Anivia wins the laning phase against Kai'Sa in League of Legends

Anivia is favored during the laning phase against Kai'Sa, winning 4 out of 5 key stat categories. Anivia holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.6Anivia
6.5Kai'Sa
Anivia and Kai'Sa farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
840Anivia
1,019Kai'Sa
Kai'Sa heavily out-damages Anivia by 179 DMG/min, dominating both short trades and all-in fights. Anivia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Kai'Sa's sustained damage advantage take over.
Economy
13,576Anivia
13,257Kai'Sa
Anivia earns 319 more gold per game than Kai'Sa, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Anivia slightly faster item completions.
Utility
2.0Anivia
0.1Kai'Sa
Anivia brings significantly more crowd control than Kai'Sa, with 1.9 more seconds of CC per minute. This large utility gap makes Anivia far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Kai'Sa should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
763Anivia
675Kai'Sa
Anivia heals and mitigates 88 more damage per minute than Kai'Sa, providing moderate extra durability. This sustain edge allows Anivia to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Kai'Sa.

Early Game vs Late Game

Early Game
Anivia
66.7%
+33.3% advantage
Anivia early game win rateAnivia66.7%
Kai'Sa early game win rateKai'Sa33.3%
Late Game
Kai'Sa
66.7%
+33.3% advantage
Anivia late game win rateAnivia33.3%
Kai'Sa late game win rateKai'Sa66.7%

Anivia dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Kai'Sa. This lopsided early game means Anivia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Kai'Sa is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Anivia. Extended games heavily favor Kai'Sa, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Anivia must aggressively press their early advantage and close out the game before Kai'Sa reaches their scaling breakpoints. If Kai'Sa survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Anivia Runes Against Kai'Sa

Domination rune tree - Anivia primary runes vs Kai'SaDomination
Electrocute - best Anivia rune vs Kai'SaCheap Shot - best Anivia rune vs Kai'SaGrisly Mementos - best Anivia rune vs Kai'SaTreasure Hunter - best Anivia rune vs Kai'Sa
Precision rune tree - Anivia secondary runes vs Kai'SaPrecision
Cut Down - best Anivia rune vs Kai'SaPresence of Mind - best Anivia rune vs Kai'Sa
100.0% WR

The Domination primary with Precision secondary combination helps Anivia maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Kai'Sa.


Anivia matchup data for League of Legends patch 26.10. The table below shows Anivia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Anivia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Anivia matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.43%1126.572911,20139.6%52.5%
49.09%1106.867511,54251.1%47.6%
42.31%1046.479410,88048.8%37.7%
42.86%984.966211,33443.8%42.4%
48.42%956.567310,99544.2%51.9%
45.65%926.771210,91251.3%41.5%
50.00%886.268611,48053.6%48.3%
57.14%776.581911,58464.3%53.1%
45.95%746.477611,94248.3%44.4%
52.86%706.776711,58852.0%53.3%
53.62%696.672011,03652.9%54.3%
53.13%646.984310,49462.1%45.7%
46.03%636.575911,85645.5%46.3%
41.27%636.472011,72063.2%31.8%
48.28%582.35419,81347.8%48.6%
44.44%544.874211,70133.3%50.0%
59.62%525.877311,92063.2%57.6%
40.82%496.372510,95640.0%41.7%
53.19%476.779111,67561.1%48.3%
62.22%456.571210,95763.2%61.5%
45.45%446.66889,81345.8%45.0%
47.73%446.573110,22554.2%40.0%
34.09%446.266911,50921.4%40.0%
52.38%426.980511,43342.1%60.9%
52.38%422.260010,16235.3%64.0%
29.27%416.570311,23146.7%19.2%
48.78%416.775510,75947.4%50.0%
50.00%405.263210,26861.1%40.9%
53.85%391.95699,82555.6%52.4%
43.59%396.87249,51950.0%33.3%
37.84%381.967010,62443.8%33.3%
50.00%386.572010,67657.1%45.8%
48.65%376.678310,45735.0%64.7%
51.35%376.376411,59450.0%52.0%
50.00%366.774310,71547.4%52.9%
57.14%356.567910,81250.0%61.9%
54.29%356.579911,86244.4%64.7%
48.57%352.25989,18044.4%52.9%
54.55%337.183511,55356.3%52.9%
41.94%313.06299,71846.7%37.5%
45.16%314.866310,82464.3%29.4%
53.33%303.263111,20562.5%50.0%
50.00%306.571511,33546.7%53.3%
79.31%296.178112,11480.0%79.0%
64.29%286.488212,06275.0%60.0%
42.86%287.076012,04833.3%47.4%
50.00%266.585411,18463.6%40.0%
42.31%266.483213,30742.9%42.1%
53.85%266.885112,66162.5%50.0%
56.00%256.284811,48977.8%43.8%
60.00%257.298711,47080.0%46.7%
37.50%246.76049,91427.3%46.1%
50.00%246.294412,73575.0%45.0%
62.50%246.869911,96560.0%64.3%
43.48%232.35619,70325.0%53.3%
47.83%236.882512,72350.0%46.7%
60.87%236.260911,24162.5%60.0%
54.55%226.880011,43050.0%57.1%
63.64%226.873610,86660.0%71.4%
40.91%226.294511,35616.7%50.0%
45.45%226.574712,56555.6%38.5%
63.64%226.572611,72866.7%61.5%
31.82%226.679811,36157.1%20.0%
38.10%212.551410,08757.1%28.6%
55.00%201.96059,72670.0%40.0%
55.00%206.161910,15250.0%60.0%
65.00%205.669411,50881.8%44.4%
57.89%193.062410,69180.0%50.0%
57.89%193.95798,40854.5%62.5%
42.11%196.580510,70550.0%33.3%
52.63%196.876311,62566.7%40.0%
63.16%196.873110,85170.0%55.6%
47.37%194.486310,19244.4%50.0%
42.11%196.776911,47937.5%45.5%
52.63%196.171510,21462.5%45.5%
44.44%183.377711,51950.0%42.9%
47.06%176.484210,77250.0%44.4%
70.59%171.761410,51780.0%66.7%
47.06%175.16709,43542.9%50.0%
29.41%176.664611,54950.0%11.1%
50.00%166.573911,95683.3%30.0%
56.25%166.281910,85350.0%66.7%
31.25%166.871110,19233.3%28.6%
46.67%156.584312,133100.0%38.5%
40.00%155.973511,31216.7%55.6%
50.00%146.269511,25460.0%44.4%
42.86%142.45879,17857.1%28.6%
42.86%141.94289,33916.7%62.5%
50.00%146.875411,27437.5%66.7%
23.08%136.075510,63920.0%25.0%
38.46%136.885413,90750.0%36.4%
53.85%133.171410,20466.7%42.9%
50.00%126.877612,62466.7%44.4%
58.33%122.770910,20766.7%50.0%
66.67%122.04568,50283.3%50.0%
33.33%122.35748,50942.9%20.0%
58.33%126.475510,31650.0%66.7%
50.00%126.873911,40550.0%50.0%
36.36%112.369311,6560.0%44.4%
45.45%112.46338,66980.0%16.7%
36.36%115.377811,69933.3%37.5%
36.36%116.96659,09037.5%33.3%
60.00%106.072910,86466.7%50.0%
40.00%106.061610,11325.0%50.0%
77.78%96.473012,91366.7%83.3%
55.56%97.069212,20333.3%66.7%
55.56%93.662110,64640.0%75.0%
22.22%96.868710,2300.0%40.0%
55.56%96.77039,52742.9%100.0%
50.00%82.04907,18450.0%50.0%
75.00%86.864911,21850.0%83.3%
50.00%88.01,22513,82575.0%25.0%
37.50%81.85209,48825.0%50.0%
42.86%72.763510,77766.7%25.0%
42.86%76.063010,71740.0%50.0%
42.86%75.68149,98066.7%25.0%
66.67%67.51,10113,35780.0%0.0%
66.67%66.08509,62260.0%100.0%
33.33%65.762710,4660.0%50.0%
66.67%61.65268,32750.0%100.0%
50.00%66.684013,57666.7%33.3%
83.33%63.693712,475100.0%75.0%
50.00%61.95589,98050.0%50.0%
80.00%56.889510,19450.0%100.0%
40.00%52.77039,24633.3%50.0%
60.00%55.859610,75566.7%50.0%
60.00%56.549710,63466.7%50.0%
20.00%55.868111,5360.0%25.0%
60.00%56.682913,9550.0%75.0%
40.00%56.568410,47250.0%0.0%

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Anivia vs Kai'Sa - Frequently Asked Questions

How does Anivia do against Kai'Sa in League of Legends?

Anivia wins the Anivia vs Kai'Sa matchup with a 50.0% win rate compared to Kai'Sa's 50.0%, a 0.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.10.

How does Anivia do against Kai'Sa in the early game?

In the early game, Anivia has the advantage against Kai'Sa with a 66.7% win rate versus 33.3%. Anivia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Anivia do against Kai'Sa in the late game?

In the late game, Kai'Sa takes over the Anivia vs Kai'Sa matchup with a 66.7% win rate compared to 33.3%. Kai'Sa scales better into team fights and objective contests after 25 minutes.

Who wins the Anivia vs Kai'Sa matchup?

Anivia wins the matchup against Kai'Sa with a 50.0% win rate in League of Legends patch 26.10. The 0.0 percentage point advantage means Anivia is slightly favored in this lane matchup based on 6 games analyzed.

What is the best Anivia build against Kai'Sa?

The best Anivia build against Kai'Sa includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Anivia runes against Kai'Sa?

The best Anivia runes against Kai'Sa use the Domination primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Anivia vs Kai'Sa matchup. See the full rune breakdown in the matchup comparison above.

Does Anivia counter Kai'Sa?

Yes, Anivia has a favorable matchup against Kai'Sa with a 50.0% win rate. Anivia slightly edges out Kai'Sa in lane based on current patch 26.10 data.

How do I play Anivia against Kai'Sa?

When playing Anivia against Kai'Sa, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.