Anivia - League of Legends Champion
Win Rate
49.7%
Pick Rate
1.9%

Aniviavs Syndra

CMage
Patch26.4
Matches1,089,240
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 28, 2026
MethodologyData Methodology

Anivia vs Syndra is a decisive matchup in LoL patch 26.4. Syndra wins with a 55.2% win rate (+10.3%) over Anivia based on 59 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Anivia build, runes, laning stats, and strategies for the Anivia vs Syndra matchup.

Anivia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Anivia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 44.8% win rateSyndra(44.8%)
Anivia - 44.8% win rate in this matchup
Anivia
44.8% WR
VS
Syndra vs Anivia matchup - 55.2% win rate
Syndra
55.2% WR

Who Wins the Anivia vs Syndra Matchup?

Syndra wins the Anivia vs Syndra matchup
Winner
Syndra
Matches: 59
44.8%
Win Rate
55.2%
6.9
CS / min
7.3
747
DMG / min
1,014
12,435
Gold / game
13,275
205
Heal / min
82
622
DMG Mitigated / min
319
1.5
CC / min
1.5
43.5%
Early Game WR
56.5%
45.7%
Late Game WR
54.3%

Anivia vs Syndra Matchup Summary

The Anivia vs Syndra matchup is a decisive matchup in League of Legends ranked play. Based on 59 recent matches analyzed, Syndra wins with a 55.2% win rate compared to Anivia's 44.8%, giving Syndra a 10.3 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Anivia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Anivia leads by 426 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a strong advantage in this matchup. Anivia players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Syndra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Anivia vs Syndra Laning Phase Breakdown

Syndra wins the laning phase against Anivia in League of Legends

Syndra is favored during the laning phase against Anivia, winning 3 out of 5 key stat categories. Syndra holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.9Anivia
7.3Syndra
Syndra edges out Anivia by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
747Anivia
1,014Syndra
Syndra heavily out-damages Anivia by 267 DMG/min, dominating both short trades and all-in fights. Anivia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
12,435Anivia
13,275Syndra
Syndra generates a commanding 840 more gold per game than Anivia. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Anivia should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.5Anivia
1.5Syndra
Both Anivia and Syndra provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
827Anivia
400Syndra
Anivia vastly out-sustains Syndra, healing and mitigating 426 more damage per minute. This massive durability gap means Anivia can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Anivia Build Against Syndra

Spellslinger's Shoes is the optimal boots choice against Syndra, providing the mobility and stats Anivia needs most in this matchup. The top-performing core items for Anivia against Syndra are Rod of Ages, Liandry's Torment and Seraph's Embrace. This combination gives Anivia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 75.0% win rate across 4 games — well above average and making it the top item path against Syndra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Anivia vs Syndra matchup.

Early Game vs Late Game

Early Game
Syndra
56.5%
+13.0% advantage
Anivia early game win rateAnivia43.5%
Syndra early game win rateSyndra56.5%
Late Game
Syndra
54.3%
+8.6% advantage
Anivia late game win rateAnivia45.7%
Syndra late game win rateSyndra54.3%

Syndra dominates the early game (first 15 minutes) with a commanding 56.5% win rate — a 13.0 percentage point lead over Anivia. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Syndra is far superior in the late game (25+ minutes), boasting a 54.3% win rate — 8.6 points above Anivia. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Anivia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Anivia Runes Against Syndra

Domination rune tree - Anivia primary runes vs SyndraDomination
Electrocute - best Anivia rune vs SyndraCheap Shot - best Anivia rune vs SyndraGrisly Mementos - best Anivia rune vs SyndraRelentless Hunter - best Anivia rune vs Syndra
Precision rune tree - Anivia secondary runes vs SyndraPrecision
Coup de Grace - best Anivia rune vs SyndraPresence of Mind - best Anivia rune vs Syndra
35.7% WR

The Domination and Precision rune setup gives Anivia the best tools to compete against Syndra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Anivia matchup data for League of Legends patch 26.4. The table below shows Anivia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Anivia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Anivia matchup win rates and stats in League of Legends patch 26.4
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.39%2126.872911,35850.0%44.9%
46.47%1706.681711,89743.4%48.9%
41.96%1436.872711,75952.5%34.5%
47.41%1164.671011,36142.5%50.7%
47.71%1106.680511,87837.2%54.5%
50.00%1047.068711,36543.1%56.6%
50.50%1026.073411,65553.5%48.3%
62.07%876.786511,87271.8%54.2%
52.38%856.973411,31653.3%51.3%
44.44%836.978311,06948.7%40.5%
51.85%826.575311,53250.0%53.5%
46.67%756.588211,74047.1%46.3%
42.67%756.276311,57831.3%51.2%
52.86%706.371211,25853.3%52.5%
53.97%637.387512,06963.3%45.5%
44.44%636.579611,83534.6%51.4%
39.68%631.65249,15750.0%32.4%
54.10%616.584411,01350.0%60.0%
44.83%596.974712,43543.5%45.7%
61.02%597.182112,56060.7%61.3%
58.49%536.783211,76045.5%67.7%
44.23%534.970411,30847.8%41.4%
57.69%536.768411,46255.6%60.0%
57.69%526.470411,06745.8%67.9%
63.46%526.775111,89165.2%62.1%
50.00%467.091811,85550.0%50.0%
44.19%446.478511,68533.3%52.0%
61.36%446.785812,42264.7%59.3%
46.51%436.781112,46760.0%39.3%
45.24%431.959711,17735.7%50.0%
54.76%422.661610,68362.5%50.0%
45.24%427.085211,67352.4%38.1%
47.62%426.973911,35457.9%39.1%
43.59%392.161710,43530.8%50.0%
57.89%386.979311,20769.6%40.0%
45.71%356.872912,32053.3%40.0%
47.06%342.659910,71660.0%41.7%
65.63%344.384710,77282.3%46.7%
54.55%331.859810,18240.0%66.7%
42.42%333.36609,94953.3%33.3%
53.33%306.584013,38455.6%52.4%
66.67%306.580912,18460.0%70.0%
50.00%305.069910,02856.3%42.9%
62.07%296.278513,33383.3%56.5%
29.63%276.599212,33718.2%37.5%
55.56%276.878412,61772.7%43.8%
53.85%266.892211,37761.5%46.1%
44.00%256.864310,57453.9%33.3%
60.00%256.178212,02575.0%52.9%
48.00%252.15979,76153.9%41.7%
56.00%256.91,01913,29442.9%61.1%
52.00%252.25969,58150.0%53.3%
54.17%242.76858,47147.1%71.4%
50.00%246.11,01312,35744.4%53.3%
52.17%245.692511,88257.1%50.0%
62.50%246.974211,31572.7%53.9%
50.00%241.959710,46557.1%47.1%
70.83%243.458710,14450.0%81.3%
68.18%236.679512,19566.7%69.2%
47.83%236.677811,63361.5%30.0%
52.38%227.482712,21666.7%41.7%
50.00%221.84898,88945.5%54.5%
63.64%222.16059,82350.0%75.0%
50.00%225.070511,62357.1%46.7%
54.55%221.95948,77572.7%36.4%
59.09%221.859110,31471.4%53.3%
45.45%221.95089,98150.0%42.9%
26.32%196.765511,72125.0%27.3%
52.94%176.488212,95744.4%62.5%
75.00%166.679412,43283.3%70.0%
53.33%164.174911,90880.0%40.0%
43.75%165.778611,93250.0%33.3%
37.50%167.07209,81554.5%0.0%
81.25%166.47889,85370.0%100.0%
46.67%155.77259,59050.0%40.0%
46.67%155.56748,96854.5%25.0%
40.00%156.877313,14857.1%25.0%
42.86%146.485212,17880.0%22.2%
35.71%141.65439,7230.0%55.6%
35.71%142.14728,22950.0%16.7%
38.46%136.052710,24833.3%50.0%
38.46%135.483113,811100.0%27.3%
30.77%135.87307,58730.0%33.3%
33.33%127.180411,57640.0%28.6%
25.00%123.46779,80150.0%0.0%
58.33%126.498411,96471.4%40.0%
33.33%121.65229,58342.9%20.0%
45.45%116.779111,7280.0%71.4%
63.64%111.558610,75666.7%62.5%
54.55%115.376410,61628.6%100.0%
63.64%117.786013,18366.7%60.0%
36.36%115.670711,49366.7%25.0%
36.36%116.07149,9750.0%80.0%
36.36%116.370310,54220.0%50.0%
63.64%116.780212,32850.0%71.4%
70.00%102.86199,52833.3%85.7%
50.00%107.272810,47633.3%75.0%
30.00%106.799312,58366.7%14.3%
20.00%106.999711,61625.0%16.7%
70.00%107.069712,15183.3%50.0%
40.00%106.579111,00457.1%0.0%
66.67%107.279210,89583.3%33.3%
37.50%93.859710,19933.3%40.0%
33.33%96.865510,69220.0%50.0%
55.56%96.578113,81533.3%66.7%
44.44%92.368711,15925.0%60.0%
25.00%86.981411,74220.0%33.3%
62.50%82.455610,25260.0%66.7%
14.29%75.373911,1050.0%33.3%
57.14%76.883311,81650.0%66.7%
71.43%71.65268,33875.0%66.7%
66.67%66.781413,15550.0%75.0%
33.33%62.25859,29366.7%0.0%
33.33%64.44827,28940.0%0.0%
66.67%66.81,12014,638100.0%60.0%
66.67%67.176113,3430.0%100.0%
50.00%67.080212,13733.3%66.7%
33.33%67.194612,48850.0%25.0%
66.67%66.087611,03766.7%66.7%
50.00%65.783711,72050.0%50.0%
50.00%56.767411,95350.0%50.0%
80.00%57.373011,290100.0%50.0%
80.00%56.187315,369100.0%75.0%
80.00%56.51,05512,320100.0%66.7%
60.00%57.086613,182100.0%33.3%
60.00%56.36319,13450.0%100.0%
60.00%56.479114,209100.0%33.3%
20.00%57.187712,6340.0%25.0%
20.00%56.81,03815,65650.0%0.0%
40.00%55.986713,92150.0%33.3%
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Anivia vs Syndra - Frequently Asked Questions

How does Anivia do against Syndra in League of Legends?

Syndra wins the Anivia vs Syndra matchup with a 55.2% win rate compared to Anivia's 44.8%, a 10.3 percentage point difference. This data is based on 59 recent ranked games in patch 26.4.

How does Anivia do against Syndra in the early game?

In the early game, Syndra has the advantage against Anivia with a 56.5% win rate versus 43.5%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Anivia do against Syndra in the late game?

In the late game, Syndra takes over the Anivia vs Syndra matchup with a 54.3% win rate compared to 45.7%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Anivia vs Syndra matchup?

Syndra wins the matchup against Anivia with a 55.2% win rate in League of Legends patch 26.4. The 10.3 percentage point advantage means Syndra is significantly favored in this lane matchup based on 59 games analyzed.

What is the best Anivia build against Syndra?

The best Anivia build against Syndra includes Rod of Ages, Liandry's Torment, Seraph's Embrace with Spellslinger's Shoes. This build achieves a 75.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Anivia runes against Syndra?

The best Anivia runes against Syndra use the Domination primary tree with Precision secondary. This rune setup achieves a 35.7% win rate in the Anivia vs Syndra matchup. See the full rune breakdown in the matchup comparison above.

Does Anivia counter Syndra?

No, Anivia struggles against Syndra with only a 44.8% win rate. Syndra has the advantage in this matchup. Anivia players should focus on safe farming and avoiding extended trades to minimize Syndra's lead.

How do I play Anivia against Syndra?

When playing Anivia against Syndra, play cautiously and avoid Syndra's power spikes. Look for jungle assistance and team-dependent plays since Syndra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.