Annie, League of Legends champion
Win Rate
51.0%
Pick Rate
1.1%
Ban Rate
0.9%

Annie vs Vex

Annie C TierMageSupport
Patch
26.21
Games
2,201
Lane
All Lanes
Tier
All Tiers
Last Updated
Nov 3, 2026 UTC
Methodology
Data Methodology

Annie vs Vex is a decisive matchup in LoL patch 26.21. Annie wins with a 52.8% win rate (+5.6%) over Vex based on 36 games. Annie holds the advantage in both the early and late game. Below you'll find the best Annie build, runes, laning stats, and strategies for the Annie vs Vex matchup.

Annie Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Annie performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Annie
Annie
52.9%
VS
Vex
47.1%
Vex

Who wins Annie vs Vex?

Slight Annie edgeLow confidence

Annie wins 52.9% of these games. With this many games the true rate is most likely between 36.7% and 68.5% (95% range).

Expected
49.5%
From both champions' overall Mid win rates
Matchup effect
+3.4 pts
Observed minus expected
Sample
34 games
Lane: Mid
vs patch 26.20
—
Not enough games on both patches

Lane: Mid · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21 · Oct 27 – Nov 2

Key takeaways

  • Current data slightly favors Annie, but the sample is too limited for a strong conclusion: Annie wins 52.9% of 34 games (95% range 36.7–68.5%).
  • Both champions' overall Mid win rates predict 49.5% for Annie; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
  • Neither side reliably wins the lane: the average gold difference at 15 minutes is 317, within the margin of error (34 games).
  • Annie players pick Stormsurge far more often against Vex: 40.3% of their other Mid games, 64.7% here.
How we calculate this

Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.

A game only counts when Annie and Vex played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.

The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.

Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.

"What changes" compares Annie's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).

Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.

Annie vs Vex Laning Stats

AnnieVex

At 15 minutes

Gold difference
+317
Within the margin of error
95% range −10 to +643
XP difference
+348
Within the margin of error
95% range −9 to +706
CS difference
+6.2
Within the margin of error
95% range −0.5 to +12.9
2.79
Kills before 15 min
2.29
2.24
Deaths before 15 min
2.94
1.03
Solo kills before 15 min
0.68
2.9%
First blood
8.8%

Whole-game averages

5.7
CS / min
5.5
1,078
DMG / min
810
13,372
Gold / game
12,128
97
Heal / min
98
442
DMG Mitigated / min
457
1.1
CC / min
1.0

Annie vs Vex Win Rate by Game Length

Annie's win rate against Vex by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.

Too few games
Under 20 min
1 games
Too few games
20–25 min
2 games
Too few games
25–30 min
10 games
Too few games
30–35 min
9 games
Too few games
35+ min
12 games
Annie vs Vex95% rangeAnnie usual (Mid)

No game length stands out: Annie's results against Vex in short and long games are within the margin of error of each other.

Annie vs Vex Power Spikes

Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.

  1. Lane (15 min)EvenAnnie gold at 15: +317
  2. First itemAnnieAnnie: 11.3 min · Vex: 11.8 min
  3. Games under 20 minInsufficient data
  4. 20–30 min gamesInsufficient data
  5. 30+ min gamesInsufficient data

What Annie Changes Against Vex

Choices Annie players make noticeably more or less often in this matchup than in their other Mid games.

Best Annie Build vs Vex

Usual Annie build (Mid)

80.0% win rate · 20 games

Against Vex

Not enough matchup-specific build data: only 4 of 26 Annie games against Vex carried a complete build, which is too few to recommend an item path from. Use Annie's standard build instead.

  • Annie usually completes Malignance first, at 11.3 min (median of 23 games).
  • Vex usually completes Luden's Echo first, at 11.8 min (median of 24 games).
  • Skill priority: Q > W > E — the same as usual.

Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.

Best Annie Runes vs Vex

Usual Annie runes (Mid)

ElectrocuteElectrocute
Domination
Cheap ShotGrisly MementosRelentless Hunter
Sorcery
Absolute FocusAxiom Arcanist
Adaptive Force (offense)Adaptive Force (flex)Health Scaling (defense)

50.8% win rate · 828 games

Against Vex

Too few games for a matchup-specific rune page yet — use the usual page.

MetaBot Desktop

Plan your Annie draft in Draft Lab

Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.

  • Full 5v5 draft board
  • Lane matchup win rates
  • Pick and ban suggestions
Draft Lab in MetaBot Desktop

Annie matchup data for League of Legends patch 26.21. The table below shows Annie's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Annie build, runes, laning stats, and early vs late game analysis for that specific matchup.

Other Annie Matchups

Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.

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Annie vs Vex FAQ - Patch 26.21

Who wins Annie vs Vex?

Current data slightly favors Annie, but the sample is too limited for a strong conclusion: Annie wins 52.9% of 34 games (95% range 36.7–68.5%).

What is Annie's win rate against Vex?

Annie wins 52.9% of 34 Mid games against Vex on patch 26.21 (95% range 36.7–68.5%). Based on both champions' overall Mid win rates, 49.5% would be expected.

Does Annie counter Vex?

Not clearly. Annie wins 52.9% of 34 games against Vex, and the 95% range (36.7–68.5%) includes 50%, so neither champion reliably counters the other on current data.

Who wins lane, Annie or Vex?

Neither side reliably wins the lane: the average gold difference at 15 minutes is 317, within the margin of error (34 games).

Does Annie outscale Vex?

There are too few games of each length to tell yet.

When is Vex strongest against Annie?

On current data there is no stage of the game where Vex is ahead of Annie beyond the margin of error.

What should Annie build against Vex?

There are not enough games for a matchup-specific core, so use Annie's usual Mid core: Stormsurge, Malignance, Rabadon's Deathcap. The biggest change against Vex: Stormsurge (40.3% usually, 64.7% here).

What runes should Annie use against Vex?

Use Annie's usual Electrocute page (Domination + Sorcery); there are too few games for a matchup-specific page. The biggest change against Vex: Ultimate Hunter (17.9% usually, 35.3% here).