Cassiopeia, League of Legends champion
Win Rate
0%
Pick Rate
0%
Ban Rate
0.7%

Cassiopeia ADC Runes: Keystone & Shards

Mage
Patch
26.20
Matches
4,768,330
Lane
Bot
Tier
All Tiers
Last Updated
Oct 19, 2026 UTC
Methodology
Data Methodology

Best Bot Cassiopeia runes for LoL Patch 26.20 - Keystone from the Primary tree with Secondary secondary (0% WR, 0% pick rate). Cassiopeia's optimal primary runes are {primaryRunes}. Secondary tree: {secondaryRunes}.

Cassiopeia performs best with Keystone as the keystone rune from the Primary tree. Cassiopeia's optimal primary runes are . Cassiopeia's secondary rune tree is Secondary with . This rune setup achieves a 0% win rate (NaN% win rate difference) with a 0% pick rate across 0 Cassiopeia games.

Primary Tree

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Secondary Tree

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%Win Rate
NaN%WR Diff
%Pick Rate
This alternative Cassiopeia rune build uses Alternative Keystone as the keystone from the Primary tree. The primary runes are . Cassiopeia's secondary rune tree is Secondary with . This setup achieves a 0% win rate (NaN% win rate difference) with a 0% pick rate across 0 games.

Primary Tree

 rune tree icon

Secondary Tree

 rune tree icon
%Win Rate
NaN%WR Diff
%Pick Rate

Every Cassiopeia Bot Keystone and Secondary Tree (Patch 26.20)

103 games

Cassiopeia Bot runs Deathfire Touch in 54% of games, with a 39.3% win rate. Precision is the usual secondary tree (63%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
Deathfire TouchDeathfire TouchMost played54.4%39.3%56

Secondary trees

RunePlayersWin RateGames
PrecisionPrecisionMost played63.1%40.0%65

Pick rate is the share of Cassiopeia games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Cassiopeia Minor Runes by Tree

Every minor rune Cassiopeia players take, grouped by rune tree, with how often it is picked and how often it wins.

Precision

RunePlayersWin RateGames
Presence of MindPresence of MindMost played93.2%41.7%96
Coup de GraceCoup de Grace51.5%43.4%53
Legend: HasteLegend: Haste41.7%34.9%43

Sorcery

RunePlayersWin RateGames
Manaflow BandManaflow BandMost played93.2%39.6%96
TranscendenceTranscendence80.6%41.0%83
ScorchScorch55.3%35.1%57

Cassiopeia Stat Shards

Which stat shards Cassiopeia players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Health Scaling (defense)Health Scaling (defense)Most played90.3%40.9%93
Adaptive Force (flex)Adaptive Force (flex)88.3%40.7%91
Adaptive Force (offense)Adaptive Force (offense)85.4%39.8%88
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Cassiopeia Runes FAQ - Patch 26.20

What is the best keystone for Cassiopeia Bot?

Deathfire Touch: Cassiopeia Bot takes it in 54% of ranked games and wins 39.3% of 56 games.

What stat shards should Cassiopeia take?

Most Cassiopeia players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Cassiopeia runes in patch 26.20?

The best Cassiopeia runes in patch 26.20 use the Primary tree with , and the Secondary tree with . This rune setup achieves a 0% win rate with a 0% pick rate.

What is the win rate for Cassiopeia's best rune page?

Cassiopeia's best rune page has a 0% win rate in patch 26.20, which is NaN% compared to Cassiopeia's average win rate. This rune setup has a 0% pick rate among Cassiopeia players.

What keystone should I use on Cassiopeia?

your chosen keystone from the Primary tree is the best keystone rune for Cassiopeia in patch 26.20. This keystone synergizes well with Cassiopeia's kit and provides a 0% win rate.

What is Cassiopeia's primary rune tree?

Cassiopeia's primary rune tree is Primary. The optimal Primary runes for Cassiopeia are , with your chosen keystone being the keystone of choice.

What is Cassiopeia's secondary rune tree?

Cassiopeia's best secondary rune tree is Secondary. The recommended Secondary runes are , which complement Cassiopeia's Primary primary tree.

What are alternative rune setups for Cassiopeia?

An alternative Cassiopeia rune setup uses alternative keystone from the Primary tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Cassiopeia's runes?

Cassiopeia's top rune page has a 0% pick rate in patch 26.20. This indicates that 0% of Cassiopeia players use the your chosen keystone setup with Primary and Secondary trees.