Karmavs Vayne
Karma vs Vayne is a decisive matchup in LoL patch 26.11. Karma wins with a 57.1% win rate (+14.3%) over Vayne based on 7 games. Karma holds the advantage in both the early and late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Vayne matchup.
Karma Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Karma vs Vayne Matchup?
Karma vs Vayne Matchup Summary
The Karma vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Karma wins with a 57.1% win rate compared to Vayne's 42.9%, giving Karma a 14.3 percentage point advantage. Karma dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Karma leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karma players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karma vs Vayne Laning Phase Breakdown
Karma is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Karma holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.
Best Karma Build Against Vayne
Ionian Boots of Lucidity is the optimal boots choice against Vayne, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Vayne are Echoes of Helia, Moonstone Renewer and Ardent Censer. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Vayne matchup.
Early Game vs Late Game
Karma50.0%
Vayne50.0%Karma66.7%Vayne33.3%The early game (first 15 minutes) is a toss-up between Karma and Vayne, with Karma holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Karma is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Vayne. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.
Karma holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Karma Runes Against Vayne
Sorcery
Precision
Running Sorcery primary with Precision secondary allows Karma to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Karma matchup data for League of Legends patch 26.11. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.13% | 230 | 1.4 | 387 | 8,843 | 50.0% | 48.5% | |
| 50.29% | 173 | 1.3 | 372 | 8,944 | 43.8% | 54.1% | |
| 54.19% | 155 | 1.3 | 383 | 8,585 | 52.0% | 56.3% | |
| 47.10% | 155 | 1.3 | 398 | 8,645 | 48.4% | 46.1% | |
| 47.76% | 134 | 1.3 | 378 | 8,324 | 49.2% | 46.4% | |
| 49.61% | 129 | 1.3 | 419 | 8,625 | 51.7% | 47.8% | |
| 55.12% | 127 | 1.4 | 399 | 9,260 | 60.8% | 51.3% | |
| 45.54% | 112 | 1.3 | 397 | 8,211 | 53.7% | 33.3% | |
| 46.07% | 89 | 1.3 | 373 | 8,035 | 47.7% | 44.4% | |
| 54.65% | 86 | 1.4 | 428 | 9,410 | 47.1% | 59.6% | |
| 53.57% | 84 | 1.2 | 358 | 9,355 | 56.0% | 52.5% | |
| 39.29% | 84 | 1.2 | 395 | 9,014 | 29.0% | 45.3% | |
| 54.88% | 82 | 1.1 | 420 | 8,527 | 55.0% | 54.8% | |
| 42.50% | 80 | 1.4 | 377 | 9,248 | 45.7% | 40.0% | |
| 37.50% | 80 | 1.3 | 410 | 9,379 | 40.0% | 36.0% | |
| 56.52% | 69 | 1.2 | 377 | 9,213 | 41.7% | 64.4% | |
| 50.79% | 63 | 1.4 | 303 | 7,864 | 47.4% | 56.0% | |
| 30.00% | 60 | 1.3 | 387 | 8,228 | 32.4% | 26.9% | |
| 43.64% | 55 | 1.2 | 363 | 8,143 | 44.0% | 43.3% | |
| 40.00% | 55 | 1.1 | 352 | 8,442 | 48.3% | 30.8% | |
| 50.00% | 52 | 1.3 | 459 | 9,528 | 46.1% | 51.3% | |
| 54.00% | 50 | 1.1 | 419 | 8,615 | 56.0% | 52.0% | |
| 53.06% | 49 | 1.2 | 372 | 8,558 | 60.0% | 48.3% | |
| 51.11% | 45 | 1.3 | 471 | 9,133 | 64.7% | 42.9% | |
| 53.33% | 45 | 1.2 | 359 | 9,158 | 59.1% | 47.8% | |
| 50.00% | 44 | 1.2 | 427 | 9,348 | 57.9% | 44.0% | |
| 52.50% | 40 | 2.2 | 477 | 10,143 | 58.3% | 50.0% | |
| 55.00% | 40 | 1.2 | 461 | 9,167 | 42.1% | 66.7% | |
| 60.53% | 38 | 1.6 | 426 | 8,228 | 55.6% | 65.0% | |
| 24.24% | 33 | 1.3 | 437 | 8,447 | 17.6% | 31.3% | |
| 53.33% | 30 | 1.3 | 379 | 8,391 | 57.1% | 50.0% | |
| 42.31% | 26 | 1.2 | 434 | 9,707 | 57.1% | 36.8% | |
| 62.50% | 24 | 1.1 | 432 | 8,314 | 66.7% | 55.6% | |
| 42.11% | 19 | 1.1 | 369 | 8,056 | 33.3% | 50.0% | |
| 62.50% | 16 | 1.3 | 349 | 9,268 | 25.0% | 75.0% | |
| 46.67% | 15 | 1.3 | 341 | 9,064 | 42.9% | 50.0% | |
| 66.67% | 15 | 1.5 | 427 | 9,567 | 60.0% | 70.0% | |
| 71.43% | 14 | 2.2 | 433 | 10,064 | 50.0% | 80.0% | |
| 61.54% | 13 | 2.0 | 597 | 10,353 | 80.0% | 50.0% | |
| 61.54% | 13 | 3.8 | 588 | 8,945 | 37.5% | 100.0% | |
| 38.46% | 13 | 1.4 | 326 | 9,120 | 40.0% | 37.5% | |
| 46.15% | 13 | 1.5 | 327 | 8,213 | 62.5% | 20.0% | |
| 38.46% | 13 | 1.5 | 380 | 9,826 | 0.0% | 50.0% | |
| 50.00% | 12 | 5.1 | 677 | 10,738 | 66.7% | 44.4% | |
| 50.00% | 12 | 1.6 | 449 | 8,142 | 40.0% | 57.1% | |
| 66.67% | 12 | 1.8 | 489 | 9,697 | 50.0% | 75.0% | |
| 72.73% | 11 | 4.3 | 732 | 9,826 | 100.0% | 57.1% | |
| 55.56% | 9 | 4.9 | 570 | 11,178 | 66.7% | 50.0% | |
| 33.33% | 9 | 2.7 | 557 | 7,771 | 25.0% | 40.0% | |
| 33.33% | 9 | 1.7 | 609 | 8,328 | 33.3% | 33.3% | |
| 50.00% | 8 | 3.5 | 578 | 11,281 | 50.0% | 50.0% | |
| 37.50% | 8 | 3.1 | 513 | 8,660 | 60.0% | 0.0% | |
| 25.00% | 8 | 2.6 | 591 | 9,610 | 0.0% | 33.3% | |
| 14.29% | 7 | 2.2 | 431 | 8,031 | 20.0% | 0.0% | |
| 71.43% | 7 | 6.2 | 627 | 11,813 | 100.0% | 66.7% | |
| 57.14% | 7 | 5.2 | 630 | 8,948 | 50.0% | 66.7% | |
| 57.14% | 7 | 2.3 | 490 | 8,441 | 0.0% | 80.0% | |
| 71.43% | 7 | 1.1 | 434 | 9,673 | 100.0% | 60.0% | |
| 42.86% | 7 | 3.4 | 468 | 9,153 | 100.0% | 20.0% | |
| 33.33% | 6 | 4.8 | 857 | 9,043 | 50.0% | 0.0% | |
| 33.33% | 6 | 2.1 | 529 | 9,934 | 33.3% | 33.3% | |
| 33.33% | 6 | 6.2 | 721 | 11,007 | 50.0% | 25.0% | |
| 33.33% | 6 | 1.4 | 378 | 8,779 | 33.3% | 33.3% | |
| 40.00% | 5 | 6.0 | 730 | 11,863 | 100.0% | 25.0% | |
| 40.00% | 5 | 2.3 | 354 | 9,378 | 66.7% | 0.0% | |
| 80.00% | 5 | 5.7 | 625 | 9,922 | 50.0% | 100.0% | |
| 20.00% | 5 | 3.3 | 576 | 7,763 | 0.0% | 50.0% | |
| 60.00% | 5 | 3.1 | 460 | 9,865 | 100.0% | 50.0% | |
| 60.00% | 5 | 4.6 | 775 | 11,657 | 0.0% | 75.0% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Karma vs Vayne - Frequently Asked Questions
How does Karma do against Vayne in League of Legends?
Karma wins the Karma vs Vayne matchup with a 57.1% win rate compared to Vayne's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.11.
How does Karma do against Vayne in the early game?
In the early game, Karma has the advantage against Vayne with a 50.0% win rate versus 50.0%. Karma players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karma do against Vayne in the late game?
In the late game, Karma takes over the Karma vs Vayne matchup with a 66.7% win rate compared to 33.3%. Karma scales better into team fights and objective contests after 25 minutes.
Who wins the Karma vs Vayne matchup?
Karma wins the matchup against Vayne with a 57.1% win rate in League of Legends patch 26.11. The 14.3 percentage point advantage means Karma is significantly favored in this lane matchup based on 7 games analyzed.
What is the best Karma build against Vayne?
The best Karma build against Vayne includes Echoes of Helia, Moonstone Renewer, Ardent Censer with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Karma runes against Vayne?
The best Karma runes against Vayne use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karma vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Karma counter Vayne?
Yes, Karma has a favorable matchup against Vayne with a 57.1% win rate. Karma strongly counters Vayne in lane based on current patch 26.11 data.
How do I play Karma against Vayne?
When playing Karma against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.