Karma - League of Legends Champion
Win Rate
49.6%
Pick Rate
2.3%

Karmavs Seraphine

CMageSupport
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Karma vs Seraphine is a very close matchup in LoL patch 26.11. Seraphine wins with a 50.8% win rate (+1.6%) over Karma based on 258 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Seraphine matchup.

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Karma Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karma - 49.2% win rate in this matchup
Karma
49.2% WR
VS
Seraphine vs Karma matchup - 50.8% win rate
Seraphine
50.8% WR

Who Wins the Karma vs Seraphine Matchup?

Seraphine wins the Karma vs Seraphine matchup
Winner
Seraphine
Matches: 258
49.2%
Win Rate
50.8%
1.3
CS / min
1.5
387
DMG / min
444
8,853
Gold / game
9,247
234
Heal / min
312
466
DMG Mitigated / min
359
0.9
CC / min
1.1
49.5%
Early Game WR
50.5%
49.0%
Late Game WR
51.0%

Karma vs Seraphine Matchup Summary

The Karma vs Seraphine matchup is a very close matchup in League of Legends ranked play. Based on 258 recent matches analyzed, Seraphine wins with a 50.8% win rate compared to Karma's 49.2%, giving Seraphine a 1.6 percentage point advantage. Seraphine holds a slight edge in both the early and late game, but the margins are thin enough that individual skill and jungle attention will often determine the outcome. Karma can still find windows through outplays and team coordination. The most significant statistical gap is in crowd control, where Seraphine leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Seraphine is slightly favored, Karma can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Seraphine's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karma vs Seraphine Laning Phase Breakdown

Seraphine wins the laning phase against Karma in League of Legends

Seraphine is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.3Karma
1.5Seraphine
Karma and Seraphine farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
387Karma
444Seraphine
Seraphine deals 57 more champion damage per minute than Karma. While noticeable in extended trades, this gap can be offset by Karma choosing favorable fight windows, such as engaging when Seraphine's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
8,853Karma
9,247Seraphine
Seraphine earns 394 more gold per game than Karma, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Seraphine slightly faster item completions.
Utility
0.9Karma
1.1Seraphine
Both Karma and Seraphine provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
700Karma
671Seraphine
Karma and Seraphine have comparable sustain profiles, with only 29 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Best Karma Build Against Seraphine

Ionian Boots of Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Seraphine are Echoes of Helia, Moonstone Renewer and Ardent Censer. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 5 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
50.5%
+1.0% advantage
Karma early game win rateKarma49.5%
Seraphine early game win rateSeraphine50.5%
Late Game
Seraphine
51.0%
+1.9% advantage
Karma late game win rateKarma49.0%
Seraphine late game win rateSeraphine51.0%

The early game (first 15 minutes) is a toss-up between Karma and Seraphine, with Seraphine holding a razor-thin 50.5% win rate edge (+1.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Late game (25+ minutes) is equally balanced, with Seraphine at 51.0% win rate — only 1.9 points ahead of Karma. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

This matchup is remarkably even at every stage of the game. Neither Karma nor Seraphine has a phase-specific advantage, making this a pure skill matchup where individual mechanics, decision-making, and team coordination determine the outcome.

Best Karma Runes Against Seraphine

Sorcery rune tree - Karma primary runes vs SeraphineSorcery
Summon Aery - best Karma rune vs SeraphineManaflow Band - best Karma rune vs SeraphineTranscendence - best Karma rune vs SeraphineGathering Storm - best Karma rune vs Seraphine
Resolve rune tree - Karma secondary runes vs SeraphineResolve
Font of Life - best Karma rune vs SeraphineRevitalize - best Karma rune vs Seraphine
50.6% WR

The Sorcery primary with Resolve secondary combination helps Karma maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Seraphine.


Karma matchup data for League of Legends patch 26.11. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karma matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.22%2581.33878,85349.5%49.0%
49.50%2001.33728,87740.5%54.8%
46.41%1811.33948,65848.7%44.8%
53.14%1751.33878,66753.2%53.1%
48.13%1601.33758,23648.1%48.1%
49.66%1451.34108,47051.4%48.0%
56.12%1391.43999,18064.4%50.0%
45.67%1271.33998,31652.7%35.9%
46.08%1021.33628,09347.9%44.4%
53.54%991.24208,56056.3%51.0%
42.27%971.23968,91133.3%48.3%
54.26%941.54329,47744.4%60.3%
53.76%931.23659,37451.7%54.7%
42.86%911.43869,43143.2%42.6%
35.29%851.34099,20435.3%35.3%
53.75%801.33809,14339.3%61.5%
52.86%701.43097,91950.0%57.1%
35.29%681.33828,32538.5%31.0%
39.34%611.13598,63746.7%32.3%
42.62%611.23628,07544.4%41.2%
48.33%601.34519,35344.4%50.0%
48.21%561.14118,49350.0%46.4%
50.94%531.23728,55256.5%46.7%
52.00%501.23549,07862.5%42.3%
48.00%501.44618,99057.1%41.4%
53.06%491.24558,90039.1%65.4%
51.06%471.34189,41257.9%46.4%
58.70%461.54018,14157.1%60.0%
52.38%422.349710,25758.3%50.0%
26.32%381.34138,43721.1%31.6%
50.00%341.33918,33953.3%47.4%
50.00%321.34379,38566.7%40.0%
62.50%241.14328,31466.7%55.6%
45.45%221.13608,17645.5%45.5%
52.63%191.33709,41050.0%54.5%
64.71%171.63939,42425.0%76.9%
60.00%151.956410,05671.4%50.0%
53.33%151.43348,38570.0%20.0%
66.67%151.54279,56760.0%70.0%
71.43%142.243310,06450.0%80.0%
57.14%143.65638,88737.5%83.3%
35.71%141.33169,08440.0%33.3%
42.86%141.53889,9010.0%54.5%
53.85%131.64538,02650.0%57.1%
61.54%131.74719,48240.0%75.0%
50.00%125.167710,73866.7%44.4%
72.73%114.37329,826100.0%57.1%
60.00%105.056310,34375.0%50.0%
30.00%103.34099,375100.0%12.5%
55.56%93.866111,56750.0%57.1%
33.33%92.75577,77125.0%40.0%
22.22%91.94017,81733.3%0.0%
33.33%91.76098,32833.3%33.3%
33.33%92.66409,7060.0%42.9%
62.50%86.260711,729100.0%57.1%
62.50%85.35869,13350.0%75.0%
62.50%82.65018,50233.3%80.0%
37.50%83.15138,66060.0%0.0%
28.57%72.24819,44925.0%33.3%
42.86%75.08309,01660.0%0.0%
71.43%71.14349,673100.0%60.0%
28.57%71.33788,64833.3%25.0%
33.33%63.15667,42925.0%50.0%
50.00%64.577111,1260.0%75.0%
33.33%66.272111,00750.0%25.0%
40.00%52.33549,37866.7%0.0%
80.00%55.76259,92250.0%100.0%
40.00%56.073011,863100.0%25.0%
40.00%51.33296,23750.0%0.0%
40.00%54.27219,29125.0%100.0%
80.00%51.24579,786100.0%50.0%
60.00%53.14609,865100.0%50.0%

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Karma vs Seraphine - Frequently Asked Questions

How does Karma do against Seraphine in League of Legends?

Seraphine wins the Karma vs Seraphine matchup with a 50.8% win rate compared to Karma's 49.2%, a 1.6 percentage point difference. This data is based on 258 recent ranked games in patch 26.11.

How does Karma do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Karma with a 50.5% win rate versus 49.5%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karma do against Seraphine in the late game?

In the late game, Seraphine takes over the Karma vs Seraphine matchup with a 51.0% win rate compared to 49.0%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Karma vs Seraphine matchup?

Seraphine wins the matchup against Karma with a 50.8% win rate in League of Legends patch 26.11. The 1.6 percentage point advantage means Seraphine is slightly favored in this lane matchup based on 258 games analyzed.

What is the best Karma build against Seraphine?

The best Karma build against Seraphine includes Echoes of Helia, Moonstone Renewer, Ardent Censer with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Karma runes against Seraphine?

The best Karma runes against Seraphine use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 50.6% win rate in the Karma vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Karma counter Seraphine?

No, Karma struggles against Seraphine with only a 49.2% win rate. Seraphine has the advantage in this matchup. Karma players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Karma against Seraphine?

When playing Karma against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.