- Win Rate
- 49.4%
- Pick Rate
- 2.6%
- Ban Rate
- 2.0%
Karma vs Seraphine
- Patch
- 26.21
- Games
- 5,236
- Lane
- All Lanes
- Tier
- All Tiers
- Last Updated
- Nov 3, 2026 UTC
- Author
- Dakota Chinnick
- Methodology
- Data Methodology
Karma vs Seraphine is a moderate matchup in LoL patch 26.21. Seraphine wins with a 51.3% win rate (+2.5%) over Karma based on 314 games. Seraphine wins the early laning phase while Karma scales better into the late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Seraphine matchup.
Karma Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who wins Karma vs Seraphine?
Karma wins 49.5% of these games. With this many games the true rate is most likely between 43.9% and 55.1% (95% range).
- Expected
- 49.2% From both champions' overall Support win rates
- Matchup effect
- +0.3 pts Observed minus expected
- Sample
- 299 games Lane: Support
- vs patch 26.20
- +3.2 pts Within normal patch-to-patch noise
Lane: Support · Ranked Solo/Duo & Flex · North America server · All ranks · Patch 26.21 · Oct 27 – Nov 3
Key takeaways
- Karma vs Seraphine is an even matchup: Karma wins 49.5% of 299 games, and the 95% range (43.9–55.1%) comfortably includes 50%.
- Both champions' overall Support win rates predict 49.2% for Karma; the result is within the margin of error of that, so this matchup mostly reflects the two champions' general strength.
- Seraphine usually wins the lane: 124 gold ahead of Karma at 15 minutes on average (297 games with a 15-minute snapshot).
- Karma players pick Ability Haste (offense) much less often against Seraphine: 77.4% of their other Support games, 72.2% here.
How we calculate this
Games: ranked Solo/Duo and Flex games on the North America server from the patch shown. Remakes (games under 5 minutes) are excluded.
A game only counts when Karma and Seraphine played the same position on opposite teams, so roaming, lane swaps within a team or a champion merely being in the same game never count as this matchup.
The 95% range is a Wilson score interval. Confidence comes from how wide that range is: within ±3 points is very high, ±5 high, ±8 moderate, anything wider low. Below 20 games a matchup is not classified at all.
Expected win rate combines both champions’ win rates in this lane (same games and filters) with the log5 formula: E = A(1−B) / (A(1−B) + B(1−A)). Matchup effect = observed − expected.
"What changes" compares Karma's choices in this matchup with the same champion's other games in the same lane, and lists a change only when it is at least 3 points and statistically significant (two-proportion z-test, |z| ≥ 2, 20+ games).
Results are not split by rank: the sample per rank is too small for honest per-rank matchup numbers.
Karma vs Seraphine Laning Stats
At 15 minutes
Whole-game averages
Karma vs Seraphine Win Rate by Game Length
Karma's win rate against Seraphine by game length. The dot is the win rate, the bar its 95% range and the dashed line the champion's usual win rate at that length. Lengths with fewer than 25 games are left blank.
No game length stands out: Karma's results against Seraphine in short and long games are within the margin of error of each other.
Karma vs Seraphine Power Spikes
Who is ahead at each stage, measured from these games. A stage reads "Even" when the difference is inside the margin of error, and "Insufficient data" when there are too few games to tell.
- Lane (15 min)SeraphineKarma gold at 15: −124
- First itemEvenKarma: 12.6 min · Seraphine: 12.6 min
- Games under 20 minInsufficient data
- 20–30 min gamesEvenKarma wins 46.2% of 106 games
- 30+ min gamesEvenKarma wins 51.4% of 173 games
What Karma Changes Against Seraphine
Choices Karma players make noticeably more or less often in this matchup than in their other Support games.
Ability Haste (offense)Stat shardUsually77.4%vs Seraphine72.2%−5.2 pts48.6% WR here
Sixth SenseRuneUsually17.4%vs Seraphine12.7%−4.7 pts52.6% WR here
Axiom ArcanistRuneUsually14.8%vs Seraphine19.4%+4.6 pts43.1% WR here
Best Karma Build vs Seraphine
Usual Karma build (Support)
69.2% win rate · 39 games
Against Seraphine
Not enough matchup-specific build data: only 16 of 132 Karma games against Seraphine carried a complete build, which is too few to recommend an item path from. Use Karma's standard build instead.
- Karma usually completes Echoes of Helia first, at 12.6 min (median of 113 games).
- Seraphine usually completes Echoes of Helia first, at 12.6 min (median of 121 games).
- Skill priority: Q > E > W — the same as usual.
Builds are ranked by the lower edge of their win rate range, not the raw win rate, so a build seen in a handful of wins never outranks a proven one.
Best Karma Runes vs Seraphine
Usual Karma runes (Support)
Summon Aery
76.5% win rate · 17 games
Against Seraphine
Arcane Comet
55.9% win rate · 34 games
Plan your Karma draft in Draft Lab
Draft Lab lays out both teams lane by lane with live matchup win rates, damage profiles and game-phase lean, and suggests picks and bans from current meta data.
- Full 5v5 draft board
- Lane matchup win rates
- Pick and ban suggestions
Karma matchup data for League of Legends patch 26.21. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.
Other Karma Matchups
Hardest for Karma
Easiest for Karma
Win rate and games for each matchup. Lists are ranked by the edge of the 95% range so small samples cannot top them; matchups with at least 50 games only.
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Karma vs Seraphine FAQ - Patch 26.21
Who wins Karma vs Seraphine?
Karma vs Seraphine is an even matchup: Karma wins 49.5% of 299 games, and the 95% range (43.9–55.1%) comfortably includes 50%.
What is Karma's win rate against Seraphine?
Karma wins 49.5% of 299 Support games against Seraphine on patch 26.21 (95% range 43.9–55.1%). Based on both champions' overall Support win rates, 49.2% would be expected.
Does Karma counter Seraphine?
Not clearly. Karma wins 49.5% of 299 games against Seraphine, and the 95% range (43.9–55.1%) includes 50%, so neither champion reliably counters the other on current data.
Who wins lane, Karma or Seraphine?
Seraphine usually wins the lane: 124 gold ahead of Karma at 15 minutes on average (297 games with a 15-minute snapshot).
Does Karma outscale Seraphine?
Not measurably: Karma's win rate against Seraphine in games of 25 minutes or less and in longer games is within the margin of error of each other.
When is Seraphine strongest against Karma?
Seraphine is measurably ahead in: Lane (15 min).
What should Karma build against Seraphine?
There are not enough games for a matchup-specific core, so use Karma's usual Support core: Echoes of Helia, Mikael's Blessing, Malignance.
What runes should Karma use against Seraphine?
Arcane Comet with Sorcery and Domination — 55.9% over 34 games against Seraphine. The biggest change against Seraphine: Ability Haste (offense) (77.4% usually, 72.2% here).