Karma - League of Legends Champion
Win Rate
49.5%
Pick Rate
2.3%

Karmavs Seraphine

CMageSupport
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Karma vs Seraphine is a very close matchup in LoL patch 26.14. Seraphine wins with a 50.6% win rate (+1.1%) over Karma based on 89 games. Seraphine wins the early laning phase while Karma scales better into the late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Seraphine matchup.

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Karma Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karma - 49.4% win rate in this matchup
Karma
49.4% WR
VS
Seraphine vs Karma matchup - 50.6% win rate
Seraphine
50.6% WR

Who Wins the Karma vs Seraphine Matchup?

Seraphine wins the Karma vs Seraphine matchup
Winner
Seraphine
Matches: 89
49.4%
Win Rate
50.6%
1.3
CS / min
1.4
377
DMG / min
484
8,865
Gold / game
9,283
216
Heal / min
247
458
DMG Mitigated / min
344
0.9
CC / min
1.2
40.0%
Early Game WR
60.0%
54.2%
Late Game WR
45.8%

Karma vs Seraphine Matchup Summary

The Karma vs Seraphine matchup is a very close matchup in League of Legends ranked play. Based on 89 recent matches analyzed, Seraphine wins with a 50.6% win rate compared to Karma's 49.4%, giving Seraphine a 1.1 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Karma outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Karma reaches their power spikes, while Karma should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Seraphine leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Seraphine is slightly favored, Karma can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Seraphine's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karma vs Seraphine Laning Phase Breakdown

Seraphine wins the laning phase against Karma in League of Legends

Seraphine is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.3Karma
1.4Seraphine
Karma and Seraphine farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
377Karma
484Seraphine
Seraphine heavily out-damages Karma by 107 DMG/min, dominating both short trades and all-in fights. Karma should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Seraphine's sustained damage advantage take over.
Economy
8,865Karma
9,283Seraphine
Seraphine earns 418 more gold per game than Karma, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Seraphine slightly faster item completions.
Utility
0.9Karma
1.2Seraphine
Seraphine provides 0.3 seconds more crowd control per minute than Karma, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
674Karma
591Seraphine
Karma heals and mitigates 84 more damage per minute than Seraphine, providing moderate extra durability. This sustain edge allows Karma to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Seraphine.

Best Karma Build Against Seraphine

Ionian Boots of Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Seraphine are Echoes of Helia, Moonstone Renewer and Redemption. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
60.0%
+20.0% advantage
Karma early game win rateKarma40.0%
Seraphine early game win rateSeraphine60.0%
Late Game
Karma
54.2%
+8.5% advantage
Karma late game win rateKarma54.2%
Seraphine late game win rateSeraphine45.8%

Seraphine dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Karma. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Karma is far superior in the late game (25+ minutes), boasting a 54.2% win rate — 8.5 points above Seraphine. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Seraphine must aggressively press their early advantage and close out the game before Karma reaches their scaling breakpoints. If Karma survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Karma Runes Against Seraphine

Sorcery rune tree - Karma primary runes vs SeraphineSorcery
Arcane Comet - best Karma rune vs SeraphineManaflow Band - best Karma rune vs SeraphineAbsolute Focus - best Karma rune vs SeraphineScorch - best Karma rune vs Seraphine
Domination rune tree - Karma secondary runes vs SeraphineDomination
Sixth Sense - best Karma rune vs SeraphineUltimate Hunter - best Karma rune vs Seraphine
75.0% WR

The Sorcery primary with Domination secondary combination helps Karma maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Seraphine.


Karma matchup data for League of Legends patch 26.14. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karma matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.44%891.33778,86540.0%54.2%
43.28%671.23798,53556.0%35.7%
47.27%551.24108,78327.3%60.6%
51.92%521.33528,26352.6%51.5%
52.27%441.23498,61950.0%53.3%
47.62%421.33438,15147.1%48.0%
57.50%401.23258,44258.3%57.1%
47.22%361.33948,55140.0%52.4%
40.00%351.33927,80538.9%41.2%
46.88%321.33649,06560.0%40.9%
41.94%311.34029,11140.0%42.9%
59.26%271.34459,34350.0%63.2%
62.50%241.34349,09266.7%61.1%
43.48%231.54798,82466.7%28.6%
45.45%221.42788,07250.0%41.7%
47.62%211.64779,04171.4%35.7%
47.62%211.34419,70757.1%42.9%
47.37%191.23908,20066.7%30.0%
38.89%181.54319,69533.3%40.0%
41.18%171.34719,20550.0%33.3%
62.50%161.33658,87550.0%66.7%
56.25%161.24017,44455.6%57.1%
53.33%151.14129,00975.0%45.5%
42.86%141.14898,93133.3%45.5%
84.62%131.24048,31683.3%85.7%
46.15%131.34739,16650.0%40.0%
66.67%121.13827,29255.6%100.0%
58.33%121.13498,77380.0%42.9%
45.45%111.447110,33266.7%37.5%
50.00%101.53676,88833.3%75.0%
40.00%101.23276,24516.7%75.0%
62.50%81.34009,60666.7%60.0%
42.86%74.077410,11450.0%33.3%
71.43%71.34969,271100.0%60.0%
50.00%62.45629,76933.3%66.7%
33.33%64.66128,51433.3%33.3%
33.33%64.472410,59750.0%25.0%
66.67%61.12408,45766.7%66.7%
40.00%53.05289,70150.0%33.3%
40.00%54.270210,2680.0%66.7%
80.00%51.23828,960100.0%66.7%
0.00%52.45989,8450.0%0.0%
60.00%51.13918,4340.0%100.0%
40.00%51.34968,30466.7%0.0%
60.00%51.33717,67533.3%100.0%

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Karma vs Seraphine - Frequently Asked Questions

How does Karma do against Seraphine in League of Legends?

Seraphine wins the Karma vs Seraphine matchup with a 50.6% win rate compared to Karma's 49.4%, a 1.1 percentage point difference. This data is based on 89 recent ranked games in patch 26.14.

How does Karma do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Karma with a 60.0% win rate versus 40.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karma do against Seraphine in the late game?

In the late game, Karma takes over the Karma vs Seraphine matchup with a 54.2% win rate compared to 45.8%. Karma scales better into team fights and objective contests after 25 minutes.

Who wins the Karma vs Seraphine matchup?

Seraphine wins the matchup against Karma with a 50.6% win rate in League of Legends patch 26.14. The 1.1 percentage point advantage means Seraphine is slightly favored in this lane matchup based on 89 games analyzed.

What is the best Karma build against Seraphine?

The best Karma build against Seraphine includes Echoes of Helia, Moonstone Renewer, Redemption with Ionian Boots of Lucidity. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Karma runes against Seraphine?

The best Karma runes against Seraphine use the Sorcery primary tree with Domination secondary. This rune setup achieves a 75.0% win rate in the Karma vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Karma counter Seraphine?

No, Karma struggles against Seraphine with only a 49.4% win rate. Seraphine has the advantage in this matchup. Karma players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Karma against Seraphine?

When playing Karma against Seraphine, play cautiously and avoid Seraphine's power spikes. Focus on safe farming — you outscale Seraphine in the late game. Use the matchup-specific build and runes above to optimize your chances.