
Karmavs Seraphine
Karma vs Seraphine is a very close matchup in LoL patch 26.14. Seraphine wins with a 50.6% win rate (+1.1%) over Karma based on 89 games. Seraphine wins the early laning phase while Karma scales better into the late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Seraphine matchup.
Karma Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Karma vs Seraphine Matchup?

Karma vs Seraphine Matchup Summary
The Karma vs Seraphine matchup is a very close matchup in League of Legends ranked play. Based on 89 recent matches analyzed, Seraphine wins with a 50.6% win rate compared to Karma's 49.4%, giving Seraphine a 1.1 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Karma outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Karma reaches their power spikes, while Karma should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Seraphine leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Seraphine is slightly favored, Karma can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Seraphine's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karma vs Seraphine Laning Phase Breakdown
Seraphine is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Karma Build Against Seraphine
Ionian Boots of Lucidity is the optimal boots choice against Seraphine, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Seraphine are Echoes of Helia, Moonstone Renewer and Redemption. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Seraphine matchup.
Early Game vs Late Game
Seraphine dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Karma. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Karma is far superior in the late game (25+ minutes), boasting a 54.2% win rate — 8.5 points above Seraphine. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Seraphine must aggressively press their early advantage and close out the game before Karma reaches their scaling breakpoints. If Karma survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Karma Runes Against Seraphine
The Sorcery primary with Domination secondary combination helps Karma maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Seraphine.
Karma matchup data for League of Legends patch 26.14. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 49.44% | 89 | 1.3 | 377 | 8,865 | 40.0% | 54.2% | |
| 43.28% | 67 | 1.2 | 379 | 8,535 | 56.0% | 35.7% | |
| 47.27% | 55 | 1.2 | 410 | 8,783 | 27.3% | 60.6% | |
| 51.92% | 52 | 1.3 | 352 | 8,263 | 52.6% | 51.5% | |
| 52.27% | 44 | 1.2 | 349 | 8,619 | 50.0% | 53.3% | |
| 47.62% | 42 | 1.3 | 343 | 8,151 | 47.1% | 48.0% | |
| 57.50% | 40 | 1.2 | 325 | 8,442 | 58.3% | 57.1% | |
| 47.22% | 36 | 1.3 | 394 | 8,551 | 40.0% | 52.4% | |
| 40.00% | 35 | 1.3 | 392 | 7,805 | 38.9% | 41.2% | |
| 46.88% | 32 | 1.3 | 364 | 9,065 | 60.0% | 40.9% | |
| 41.94% | 31 | 1.3 | 402 | 9,111 | 40.0% | 42.9% | |
| 59.26% | 27 | 1.3 | 445 | 9,343 | 50.0% | 63.2% | |
| 62.50% | 24 | 1.3 | 434 | 9,092 | 66.7% | 61.1% | |
| 43.48% | 23 | 1.5 | 479 | 8,824 | 66.7% | 28.6% | |
| 45.45% | 22 | 1.4 | 278 | 8,072 | 50.0% | 41.7% | |
| 47.62% | 21 | 1.6 | 477 | 9,041 | 71.4% | 35.7% | |
| 47.62% | 21 | 1.3 | 441 | 9,707 | 57.1% | 42.9% | |
| 47.37% | 19 | 1.2 | 390 | 8,200 | 66.7% | 30.0% | |
| 38.89% | 18 | 1.5 | 431 | 9,695 | 33.3% | 40.0% | |
| 41.18% | 17 | 1.3 | 471 | 9,205 | 50.0% | 33.3% | |
| 62.50% | 16 | 1.3 | 365 | 8,875 | 50.0% | 66.7% | |
| 56.25% | 16 | 1.2 | 401 | 7,444 | 55.6% | 57.1% | |
| 53.33% | 15 | 1.1 | 412 | 9,009 | 75.0% | 45.5% | |
| 42.86% | 14 | 1.1 | 489 | 8,931 | 33.3% | 45.5% | |
| 84.62% | 13 | 1.2 | 404 | 8,316 | 83.3% | 85.7% | |
| 46.15% | 13 | 1.3 | 473 | 9,166 | 50.0% | 40.0% | |
| 66.67% | 12 | 1.1 | 382 | 7,292 | 55.6% | 100.0% | |
| 58.33% | 12 | 1.1 | 349 | 8,773 | 80.0% | 42.9% | |
| 45.45% | 11 | 1.4 | 471 | 10,332 | 66.7% | 37.5% | |
| 50.00% | 10 | 1.5 | 367 | 6,888 | 33.3% | 75.0% | |
| 40.00% | 10 | 1.2 | 327 | 6,245 | 16.7% | 75.0% | |
| 62.50% | 8 | 1.3 | 400 | 9,606 | 66.7% | 60.0% | |
| 42.86% | 7 | 4.0 | 774 | 10,114 | 50.0% | 33.3% | |
| 71.43% | 7 | 1.3 | 496 | 9,271 | 100.0% | 60.0% | |
| 50.00% | 6 | 2.4 | 562 | 9,769 | 33.3% | 66.7% | |
| 33.33% | 6 | 4.6 | 612 | 8,514 | 33.3% | 33.3% | |
| 33.33% | 6 | 4.4 | 724 | 10,597 | 50.0% | 25.0% | |
| 66.67% | 6 | 1.1 | 240 | 8,457 | 66.7% | 66.7% | |
| 40.00% | 5 | 3.0 | 528 | 9,701 | 50.0% | 33.3% | |
| 40.00% | 5 | 4.2 | 702 | 10,268 | 0.0% | 66.7% | |
| 80.00% | 5 | 1.2 | 382 | 8,960 | 100.0% | 66.7% | |
| 0.00% | 5 | 2.4 | 598 | 9,845 | 0.0% | 0.0% | |
| 60.00% | 5 | 1.1 | 391 | 8,434 | 0.0% | 100.0% | |
| 40.00% | 5 | 1.3 | 496 | 8,304 | 66.7% | 0.0% | |
| 60.00% | 5 | 1.3 | 371 | 7,675 | 33.3% | 100.0% |
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Karma vs Seraphine - Frequently Asked Questions
How does Karma do against Seraphine in League of Legends?
Seraphine wins the Karma vs Seraphine matchup with a 50.6% win rate compared to Karma's 49.4%, a 1.1 percentage point difference. This data is based on 89 recent ranked games in patch 26.14.
How does Karma do against Seraphine in the early game?
In the early game, Seraphine has the advantage against Karma with a 60.0% win rate versus 40.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karma do against Seraphine in the late game?
In the late game, Karma takes over the Karma vs Seraphine matchup with a 54.2% win rate compared to 45.8%. Karma scales better into team fights and objective contests after 25 minutes.
Who wins the Karma vs Seraphine matchup?
Seraphine wins the matchup against Karma with a 50.6% win rate in League of Legends patch 26.14. The 1.1 percentage point advantage means Seraphine is slightly favored in this lane matchup based on 89 games analyzed.
What is the best Karma build against Seraphine?
The best Karma build against Seraphine includes Echoes of Helia, Moonstone Renewer, Redemption with Ionian Boots of Lucidity. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Karma runes against Seraphine?
The best Karma runes against Seraphine use the Sorcery primary tree with Domination secondary. This rune setup achieves a 75.0% win rate in the Karma vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.
Does Karma counter Seraphine?
No, Karma struggles against Seraphine with only a 49.4% win rate. Seraphine has the advantage in this matchup. Karma players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.
How do I play Karma against Seraphine?
When playing Karma against Seraphine, play cautiously and avoid Seraphine's power spikes. Focus on safe farming — you outscale Seraphine in the late game. Use the matchup-specific build and runes above to optimize your chances.
