Vaynevs Karma
Vayne vs Karma is a very close matchup in LoL patch 26.4. Vayne wins with a 50.0% win rate (+0.0%) over Karma based on 6 games. Karma wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Karma matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Karma(50.0%)Who Wins the Vayne vs Karma Matchup?
Vayne vs Karma Matchup Summary
The Vayne vs Karma matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Vayne wins with a 50.0% win rate compared to Karma's 50.0%, giving Vayne a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Karma controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karma needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Karma leads by 0.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a statistical edge, but the margin is close enough that respecting Karma's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Karma Laning Phase Breakdown
Vayne is favored during the laning phase against Karma, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Vayne Build Against Karma
Berserker's Greaves is the optimal boots choice against Karma, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Karma are Stormrazor, Trinity Force and Experimental Hexplate. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karma. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Karma matchup.
Early Game vs Late Game
Vayne0.0%Karma100.0%Vayne60.0%Karma40.0%Karma dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Karma can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Karma. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Karma must aggressively press their early advantage and close out the game before Vayne reaches their scaling breakpoints. If Vayne survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Vayne Runes Against Karma
Precision
Inspiration
The Precision primary with Inspiration secondary combination helps Vayne maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Karma.
Vayne matchup data for League of Legends patch 26.4. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 50.82% | 732 | 6.1 | 803 | 13,258 | 51.6% | 50.3% | |
| 50.47% | 643 | 5.9 | 819 | 13,610 | 51.8% | 49.5% | |
| 50.16% | 626 | 6.3 | 860 | 13,314 | 48.9% | 51.4% | |
| 53.35% | 529 | 6.1 | 868 | 13,348 | 52.2% | 54.2% | |
| 49.25% | 475 | 6.5 | 904 | 13,936 | 44.6% | 53.5% | |
| 56.36% | 402 | 6.4 | 918 | 13,991 | 52.9% | 59.4% | |
| 46.70% | 395 | 6.0 | 802 | 13,251 | 41.1% | 51.1% | |
| 52.87% | 354 | 6.4 | 922 | 14,147 | 51.2% | 53.9% | |
| 48.04% | 282 | 6.0 | 843 | 13,505 | 56.5% | 42.2% | |
| 51.29% | 271 | 6.5 | 870 | 13,472 | 53.7% | 49.3% | |
| 52.54% | 239 | 6.2 | 888 | 13,139 | 52.5% | 52.6% | |
| 54.25% | 212 | 6.5 | 917 | 14,465 | 58.5% | 51.5% | |
| 51.26% | 200 | 6.2 | 837 | 13,336 | 57.7% | 44.2% | |
| 55.00% | 200 | 6.1 | 821 | 13,161 | 49.5% | 60.0% | |
| 47.40% | 192 | 6.3 | 891 | 13,424 | 49.0% | 45.8% | |
| 55.56% | 181 | 6.0 | 858 | 13,653 | 58.1% | 53.8% | |
| 49.11% | 170 | 6.2 | 873 | 13,702 | 46.5% | 51.0% | |
| 49.63% | 135 | 5.9 | 854 | 14,043 | 46.3% | 51.9% | |
| 55.65% | 115 | 6.1 | 902 | 13,632 | 58.8% | 53.1% | |
| 53.15% | 111 | 6.0 | 842 | 11,670 | 52.9% | 53.3% | |
| 57.41% | 109 | 6.5 | 908 | 12,767 | 54.2% | 60.0% | |
| 50.00% | 106 | 6.2 | 838 | 13,925 | 48.7% | 50.8% | |
| 60.20% | 99 | 6.1 | 994 | 12,481 | 61.9% | 58.9% | |
| 54.74% | 96 | 5.8 | 1,031 | 14,056 | 43.6% | 62.5% | |
| 51.09% | 92 | 6.1 | 914 | 13,612 | 56.1% | 47.1% | |
| 45.65% | 92 | 6.3 | 845 | 13,980 | 43.6% | 47.2% | |
| 51.65% | 91 | 6.4 | 893 | 14,004 | 47.4% | 54.7% | |
| 50.59% | 87 | 6.3 | 949 | 12,103 | 52.9% | 49.0% | |
| 45.88% | 86 | 6.1 | 859 | 13,540 | 56.8% | 37.5% | |
| 45.12% | 83 | 5.7 | 603 | 11,339 | 33.3% | 54.4% | |
| 46.15% | 78 | 6.0 | 897 | 11,415 | 28.9% | 62.5% | |
| 44.16% | 77 | 6.3 | 1,391 | 12,481 | 36.7% | 48.9% | |
| 39.47% | 77 | 6.2 | 885 | 14,180 | 28.0% | 45.1% | |
| 53.73% | 68 | 5.5 | 640 | 11,628 | 26.1% | 68.2% | |
| 45.45% | 66 | 6.6 | 969 | 14,142 | 46.9% | 44.1% | |
| 49.23% | 66 | 6.3 | 1,021 | 12,932 | 52.0% | 47.5% | |
| 53.13% | 64 | 6.0 | 1,005 | 11,451 | 51.5% | 54.8% | |
| 45.31% | 64 | 6.2 | 858 | 13,545 | 44.4% | 46.0% | |
| 50.00% | 64 | 6.3 | 987 | 12,060 | 41.4% | 57.1% | |
| 59.32% | 59 | 6.1 | 997 | 11,684 | 57.1% | 61.3% | |
| 50.00% | 56 | 6.5 | 919 | 13,452 | 55.6% | 44.8% | |
| 50.00% | 54 | 6.4 | 949 | 12,100 | 40.0% | 55.9% | |
| 57.14% | 49 | 6.3 | 843 | 12,077 | 54.2% | 60.0% | |
| 53.06% | 49 | 6.4 | 945 | 12,154 | 60.9% | 46.1% | |
| 47.92% | 48 | 6.3 | 804 | 12,125 | 34.8% | 60.0% | |
| 46.81% | 48 | 6.5 | 970 | 12,453 | 47.6% | 46.1% | |
| 51.06% | 47 | 6.5 | 926 | 11,295 | 46.1% | 57.1% | |
| 51.11% | 45 | 7.2 | 998 | 13,306 | 47.6% | 54.2% | |
| 32.56% | 43 | 5.8 | 700 | 9,815 | 20.7% | 57.1% | |
| 69.77% | 43 | 6.8 | 903 | 15,255 | 71.4% | 69.0% | |
| 51.16% | 43 | 6.1 | 986 | 11,825 | 45.8% | 57.9% | |
| 52.38% | 42 | 6.6 | 877 | 12,788 | 47.6% | 57.1% | |
| 55.00% | 40 | 6.0 | 970 | 11,813 | 55.6% | 54.5% | |
| 55.00% | 40 | 5.8 | 914 | 14,584 | 47.4% | 61.9% | |
| 58.97% | 39 | 6.0 | 810 | 12,831 | 46.7% | 66.7% | |
| 48.65% | 38 | 6.0 | 840 | 11,264 | 47.6% | 50.0% | |
| 43.24% | 37 | 5.7 | 825 | 11,627 | 40.0% | 47.1% | |
| 45.71% | 35 | 6.0 | 946 | 12,638 | 27.3% | 54.2% | |
| 33.33% | 33 | 6.5 | 888 | 13,389 | 20.0% | 39.1% | |
| 48.48% | 33 | 6.0 | 728 | 13,059 | 40.0% | 55.6% | |
| 48.39% | 32 | 6.2 | 927 | 13,031 | 46.1% | 50.0% | |
| 54.84% | 31 | 6.1 | 823 | 11,632 | 50.0% | 58.8% | |
| 46.67% | 30 | 6.0 | 768 | 12,083 | 46.1% | 47.1% | |
| 63.33% | 30 | 6.4 | 886 | 12,702 | 72.7% | 57.9% | |
| 44.44% | 27 | 5.4 | 952 | 12,114 | 58.3% | 33.3% | |
| 50.00% | 26 | 6.5 | 889 | 11,516 | 46.1% | 53.9% | |
| 61.54% | 26 | 6.8 | 1,087 | 14,277 | 62.5% | 61.1% | |
| 46.15% | 26 | 5.2 | 849 | 13,311 | 70.0% | 31.3% | |
| 50.00% | 26 | 6.5 | 792 | 12,810 | 66.7% | 35.7% | |
| 46.15% | 26 | 6.6 | 1,144 | 12,906 | 46.7% | 45.5% | |
| 50.00% | 26 | 6.8 | 1,090 | 14,263 | 66.7% | 41.2% | |
| 50.00% | 24 | 6.1 | 885 | 12,729 | 54.5% | 46.1% | |
| 40.91% | 23 | 6.5 | 876 | 14,599 | 40.0% | 41.7% | |
| 60.87% | 23 | 6.3 | 909 | 14,131 | 63.6% | 58.3% | |
| 52.38% | 22 | 5.5 | 860 | 13,670 | 55.6% | 50.0% | |
| 42.86% | 21 | 6.5 | 845 | 11,534 | 33.3% | 55.6% | |
| 50.00% | 20 | 6.0 | 738 | 10,241 | 54.5% | 44.4% | |
| 63.16% | 19 | 6.3 | 1,061 | 15,663 | 100.0% | 53.3% | |
| 52.63% | 19 | 5.9 | 839 | 12,951 | 42.9% | 58.3% | |
| 52.94% | 17 | 6.0 | 1,020 | 12,523 | 40.0% | 71.4% | |
| 43.75% | 16 | 5.7 | 624 | 10,933 | 25.0% | 62.5% | |
| 62.50% | 16 | 6.8 | 817 | 11,303 | 63.6% | 60.0% | |
| 26.67% | 15 | 6.5 | 666 | 9,617 | 22.2% | 33.3% | |
| 40.00% | 15 | 4.0 | 897 | 12,231 | 57.1% | 25.0% | |
| 35.71% | 14 | 6.4 | 637 | 11,280 | 33.3% | 40.0% | |
| 42.86% | 14 | 6.9 | 846 | 11,763 | 28.6% | 57.1% | |
| 42.86% | 14 | 6.3 | 925 | 11,744 | 42.9% | 42.9% | |
| 38.46% | 13 | 4.7 | 827 | 13,522 | 16.7% | 57.1% | |
| 46.15% | 13 | 5.8 | 961 | 12,416 | 20.0% | 62.5% | |
| 46.15% | 13 | 5.9 | 982 | 14,623 | 42.9% | 50.0% | |
| 50.00% | 12 | 5.7 | 897 | 15,265 | 33.3% | 55.6% | |
| 41.67% | 12 | 6.7 | 976 | 15,743 | 40.0% | 42.9% | |
| 58.33% | 12 | 4.5 | 832 | 12,199 | 50.0% | 62.5% | |
| 58.33% | 12 | 5.9 | 781 | 11,830 | 20.0% | 85.7% | |
| 41.67% | 12 | 4.4 | 763 | 11,164 | 50.0% | 25.0% | |
| 54.55% | 11 | 2.9 | 1,055 | 15,239 | 50.0% | 57.1% | |
| 36.36% | 11 | 6.6 | 750 | 13,007 | 0.0% | 44.4% | |
| 45.45% | 11 | 4.2 | 807 | 12,513 | 50.0% | 40.0% | |
| 36.36% | 11 | 6.3 | 904 | 12,259 | 50.0% | 28.6% | |
| 22.22% | 10 | 4.2 | 658 | 9,348 | 14.3% | 50.0% | |
| 50.00% | 10 | 5.9 | 1,132 | 12,118 | 60.0% | 40.0% | |
| 40.00% | 10 | 4.8 | 773 | 12,409 | 33.3% | 50.0% | |
| 33.33% | 9 | 3.4 | 732 | 12,844 | 0.0% | 42.9% | |
| 44.44% | 9 | 4.4 | 695 | 12,824 | 50.0% | 40.0% | |
| 62.50% | 8 | 6.0 | 660 | 12,870 | 100.0% | 50.0% | |
| 25.00% | 8 | 4.2 | 758 | 11,745 | 0.0% | 66.7% | |
| 62.50% | 8 | 5.8 | 899 | 13,469 | 0.0% | 100.0% | |
| 14.29% | 7 | 6.0 | 1,054 | 15,482 | 0.0% | 16.7% | |
| 71.43% | 7 | 6.6 | 849 | 15,132 | 50.0% | 80.0% | |
| 71.43% | 7 | 4.4 | 834 | 12,500 | 100.0% | 50.0% | |
| 66.67% | 6 | 6.7 | 787 | 13,857 | 50.0% | 75.0% | |
| 33.33% | 6 | 6.9 | 753 | 11,851 | 100.0% | 0.0% | |
| 50.00% | 6 | 5.1 | 957 | 12,106 | 0.0% | 60.0% | |
| 50.00% | 6 | 6.5 | 898 | 10,842 | 75.0% | 0.0% | |
| 33.33% | 6 | 1.2 | 808 | 11,065 | 0.0% | 100.0% | |
| 50.00% | 6 | 4.0 | 775 | 15,502 | 100.0% | 40.0% | |
| 60.00% | 5 | 6.3 | 1,180 | 19,865 | 0.0% | 60.0% | |
| 25.00% | 5 | 2.4 | 567 | 11,133 | 50.0% | 0.0% | |
| 40.00% | 5 | 6.3 | 855 | 11,531 | 0.0% | 66.7% | |
| 60.00% | 5 | 6.4 | 1,099 | 15,068 | 100.0% | 33.3% | |
| 40.00% | 5 | 5.1 | 877 | 11,537 | 0.0% | 100.0% | |
| 40.00% | 5 | 3.1 | 1,070 | 12,851 | 50.0% | 0.0% | |
| 40.00% | 5 | 2.7 | 706 | 14,287 | 0.0% | 50.0% | |
| 0.00% | 5 | 6.0 | 781 | 12,150 | 0.0% | 0.0% | |
| 60.00% | 5 | 6.9 | 1,192 | 13,262 | 0.0% | 100.0% | |
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Vayne vs Karma - Frequently Asked Questions
How does Vayne do against Karma in League of Legends?
Vayne wins the Vayne vs Karma matchup with a 50.0% win rate compared to Karma's 50.0%, a 0.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.4.
How does Vayne do against Karma in the early game?
In the early game, Karma has the advantage against Vayne with a 100.0% win rate versus 0.0%. Karma players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Karma in the late game?
In the late game, Vayne takes over the Vayne vs Karma matchup with a 60.0% win rate compared to 40.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Karma matchup?
Vayne wins the matchup against Karma with a 50.0% win rate in League of Legends patch 26.4. The 0.0 percentage point advantage means Vayne is slightly favored in this lane matchup based on 6 games analyzed.
What is the best Vayne build against Karma?
The best Vayne build against Karma includes Stormrazor, Trinity Force, Experimental Hexplate with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Karma?
The best Vayne runes against Karma use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Karma matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Karma?
Yes, Vayne has a favorable matchup against Karma with a 50.0% win rate. Vayne slightly edges out Karma in lane based on current patch 26.4 data.
How do I play Vayne against Karma?
When playing Vayne against Karma, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Karma. Build the recommended items and runes for this specific matchup for the best results.