Vaynevs Karma
Vayne vs Karma is a decisive matchup in LoL patch 26.11. Karma wins with a 57.1% win rate (+14.3%) over Vayne based on 7 games. Vayne wins the early laning phase while Karma scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Karma matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Karma Matchup?
Vayne vs Karma Matchup Summary
The Vayne vs Karma matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Karma wins with a 57.1% win rate compared to Vayne's 42.9%, giving Karma a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Karma outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Karma reaches their power spikes, while Karma should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Karma leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Karma has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karma overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Karma Laning Phase Breakdown
Karma is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Karma holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.
Best Vayne Build Against Karma
Slightly Magical Footwear is the optimal boots choice against Karma, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Karma are Voltaic Cyclosword, Umbral Glaive and Bastionbreaker. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Karma matchup.
Early Game vs Late Game
Vayne50.0%
Karma50.0%Vayne33.3%Karma66.7%The early game (first 15 minutes) is a toss-up between Vayne and Karma, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Karma is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Vayne. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.
The power dynamics shift as the game progresses — Vayne has the edge early, but Karma gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Vayne Runes Against Karma
Precision
Resolve
The Precision and Resolve rune setup gives Vayne the best tools to compete against Karma in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 45.97% | 409 | 6.0 | 785 | 12,876 | 44.2% | 47.4% | |
| 47.86% | 397 | 6.0 | 788 | 12,727 | 46.3% | 49.1% | |
| 45.43% | 372 | 5.8 | 801 | 12,777 | 43.8% | 46.7% | |
| 47.43% | 331 | 6.2 | 894 | 13,160 | 46.8% | 47.9% | |
| 51.82% | 330 | 6.0 | 856 | 12,741 | 51.5% | 52.1% | |
| 51.91% | 314 | 6.2 | 832 | 13,072 | 50.7% | 52.9% | |
| 54.39% | 239 | 6.3 | 922 | 13,515 | 49.5% | 58.3% | |
| 53.14% | 239 | 6.3 | 867 | 13,589 | 47.6% | 57.4% | |
| 53.61% | 166 | 6.0 | 885 | 12,334 | 46.3% | 60.7% | |
| 55.56% | 135 | 6.2 | 861 | 13,139 | 62.1% | 50.6% | |
| 50.37% | 135 | 6.5 | 917 | 12,026 | 50.0% | 50.7% | |
| 44.78% | 134 | 5.9 | 777 | 13,468 | 44.0% | 45.2% | |
| 50.00% | 130 | 6.0 | 802 | 13,077 | 42.9% | 55.4% | |
| 44.25% | 113 | 6.1 | 773 | 13,036 | 37.8% | 48.5% | |
| 43.27% | 104 | 6.1 | 778 | 12,248 | 34.1% | 50.0% | |
| 46.53% | 101 | 6.4 | 794 | 13,635 | 36.1% | 52.3% | |
| 59.38% | 96 | 6.5 | 863 | 13,191 | 65.3% | 53.2% | |
| 51.04% | 96 | 5.8 | 875 | 12,992 | 42.2% | 58.8% | |
| 33.33% | 90 | 5.5 | 643 | 10,336 | 12.8% | 49.0% | |
| 47.06% | 85 | 5.7 | 844 | 12,915 | 44.1% | 49.0% | |
| 43.53% | 85 | 5.8 | 620 | 11,219 | 41.9% | 44.4% | |
| 43.37% | 83 | 5.7 | 820 | 11,436 | 40.5% | 45.6% | |
| 48.78% | 82 | 6.3 | 1,134 | 12,809 | 56.0% | 45.6% | |
| 45.68% | 81 | 6.4 | 878 | 12,894 | 48.6% | 43.5% | |
| 58.23% | 79 | 6.3 | 795 | 12,901 | 52.8% | 62.8% | |
| 43.06% | 72 | 6.3 | 876 | 13,758 | 31.8% | 48.0% | |
| 60.00% | 70 | 6.2 | 1,306 | 11,706 | 55.2% | 63.4% | |
| 60.87% | 69 | 6.2 | 920 | 10,741 | 57.1% | 63.4% | |
| 59.09% | 66 | 6.3 | 896 | 13,373 | 60.0% | 58.3% | |
| 53.45% | 58 | 5.9 | 814 | 12,180 | 59.1% | 50.0% | |
| 45.28% | 53 | 6.2 | 833 | 12,384 | 45.5% | 45.2% | |
| 53.19% | 47 | 6.0 | 858 | 13,092 | 47.8% | 58.3% | |
| 51.11% | 45 | 6.0 | 916 | 11,413 | 43.5% | 59.1% | |
| 51.16% | 43 | 6.1 | 982 | 13,353 | 50.0% | 52.0% | |
| 42.86% | 42 | 6.5 | 954 | 12,899 | 44.4% | 41.7% | |
| 56.10% | 41 | 6.0 | 985 | 11,624 | 61.9% | 50.0% | |
| 40.00% | 40 | 6.1 | 685 | 10,861 | 30.0% | 50.0% | |
| 57.50% | 40 | 6.2 | 906 | 13,611 | 60.9% | 52.9% | |
| 48.72% | 39 | 6.3 | 1,016 | 11,280 | 55.0% | 42.1% | |
| 52.63% | 38 | 5.9 | 867 | 13,872 | 60.0% | 50.0% | |
| 23.68% | 38 | 5.9 | 867 | 11,771 | 21.4% | 25.0% | |
| 47.37% | 38 | 5.8 | 842 | 11,648 | 45.5% | 50.0% | |
| 50.00% | 36 | 5.6 | 830 | 13,570 | 28.6% | 55.2% | |
| 65.71% | 35 | 6.4 | 896 | 11,716 | 59.1% | 76.9% | |
| 44.12% | 34 | 5.6 | 832 | 12,022 | 38.5% | 47.6% | |
| 47.06% | 34 | 6.5 | 865 | 13,857 | 66.7% | 31.6% | |
| 44.12% | 34 | 6.0 | 737 | 9,726 | 33.3% | 56.3% | |
| 42.42% | 33 | 6.7 | 869 | 11,416 | 53.3% | 33.3% | |
| 50.00% | 32 | 6.3 | 793 | 11,238 | 50.0% | 50.0% | |
| 67.74% | 31 | 6.3 | 931 | 13,428 | 61.5% | 72.2% | |
| 43.33% | 30 | 6.3 | 685 | 10,952 | 35.3% | 53.9% | |
| 63.33% | 30 | 5.7 | 804 | 13,719 | 40.0% | 75.0% | |
| 48.28% | 29 | 6.5 | 1,066 | 11,482 | 46.7% | 50.0% | |
| 48.28% | 29 | 6.4 | 707 | 12,273 | 45.5% | 50.0% | |
| 39.29% | 28 | 6.4 | 988 | 13,401 | 40.0% | 39.1% | |
| 59.26% | 27 | 5.9 | 893 | 11,692 | 75.0% | 46.7% | |
| 55.56% | 27 | 6.5 | 821 | 12,469 | 63.6% | 50.0% | |
| 50.00% | 26 | 5.3 | 856 | 12,191 | 61.5% | 38.5% | |
| 52.00% | 25 | 6.7 | 686 | 12,233 | 50.0% | 53.9% | |
| 50.00% | 24 | 5.7 | 882 | 12,619 | 66.7% | 44.4% | |
| 50.00% | 24 | 5.9 | 835 | 12,562 | 55.6% | 46.7% | |
| 45.83% | 24 | 6.0 | 680 | 11,392 | 36.4% | 53.9% | |
| 43.48% | 23 | 6.1 | 836 | 12,870 | 20.0% | 61.5% | |
| 56.52% | 23 | 5.2 | 775 | 10,421 | 50.0% | 63.6% | |
| 43.48% | 23 | 6.3 | 866 | 12,053 | 38.5% | 50.0% | |
| 43.48% | 23 | 6.5 | 747 | 11,857 | 45.5% | 41.7% | |
| 54.55% | 22 | 6.3 | 711 | 11,367 | 41.7% | 70.0% | |
| 23.81% | 21 | 5.3 | 700 | 11,451 | 22.2% | 25.0% | |
| 40.00% | 20 | 5.9 | 815 | 13,185 | 42.9% | 38.5% | |
| 45.00% | 20 | 6.0 | 869 | 11,230 | 54.5% | 33.3% | |
| 52.63% | 19 | 6.1 | 959 | 11,858 | 54.5% | 50.0% | |
| 57.89% | 19 | 5.6 | 621 | 10,290 | 50.0% | 66.7% | |
| 63.16% | 19 | 6.3 | 870 | 12,589 | 50.0% | 72.7% | |
| 47.06% | 17 | 6.2 | 952 | 10,742 | 55.6% | 37.5% | |
| 47.06% | 17 | 5.6 | 827 | 12,267 | 66.7% | 36.4% | |
| 50.00% | 16 | 6.6 | 654 | 11,995 | 44.4% | 57.1% | |
| 60.00% | 15 | 6.5 | 833 | 11,244 | 37.5% | 85.7% | |
| 46.67% | 15 | 5.4 | 916 | 13,992 | 25.0% | 54.5% | |
| 64.29% | 14 | 5.9 | 1,048 | 14,040 | 75.0% | 60.0% | |
| 42.86% | 14 | 6.4 | 824 | 13,966 | 75.0% | 30.0% | |
| 64.29% | 14 | 6.1 | 885 | 12,105 | 71.4% | 57.1% | |
| 75.00% | 12 | 2.3 | 887 | 17,241 | 50.0% | 80.0% | |
| 66.67% | 12 | 5.6 | 1,025 | 12,928 | 80.0% | 57.1% | |
| 41.67% | 12 | 7.0 | 988 | 13,099 | 33.3% | 44.4% | |
| 41.67% | 12 | 6.0 | 776 | 13,064 | 0.0% | 71.4% | |
| 41.67% | 12 | 5.2 | 752 | 12,500 | 40.0% | 42.9% | |
| 50.00% | 12 | 6.5 | 865 | 11,092 | 50.0% | 50.0% | |
| 36.36% | 11 | 5.9 | 937 | 11,906 | 33.3% | 40.0% | |
| 81.82% | 11 | 6.2 | 775 | 12,783 | 100.0% | 71.4% | |
| 54.55% | 11 | 3.4 | 846 | 13,743 | 33.3% | 62.5% | |
| 63.64% | 11 | 6.4 | 688 | 11,901 | 100.0% | 42.9% | |
| 50.00% | 10 | 5.7 | 1,008 | 13,341 | 50.0% | 50.0% | |
| 60.00% | 10 | 5.7 | 820 | 12,597 | 50.0% | 62.5% | |
| 40.00% | 10 | 5.5 | 926 | 11,893 | 40.0% | 40.0% | |
| 55.56% | 9 | 6.1 | 611 | 9,155 | 50.0% | 66.7% | |
| 55.56% | 9 | 2.8 | 733 | 13,297 | 66.7% | 33.3% | |
| 66.67% | 9 | 5.4 | 848 | 11,577 | 71.4% | 50.0% | |
| 33.33% | 9 | 4.9 | 594 | 10,924 | 50.0% | 0.0% | |
| 44.44% | 9 | 5.6 | 883 | 10,276 | 66.7% | 33.3% | |
| 66.67% | 9 | 3.8 | 1,039 | 13,798 | 66.7% | 66.7% | |
| 62.50% | 8 | 3.9 | 778 | 13,935 | 50.0% | 66.7% | |
| 50.00% | 8 | 3.7 | 814 | 11,207 | 33.3% | 60.0% | |
| 25.00% | 8 | 6.2 | 1,146 | 13,399 | 0.0% | 40.0% | |
| 25.00% | 8 | 5.2 | 690 | 9,102 | 16.7% | 50.0% | |
| 57.14% | 7 | 5.7 | 890 | 14,669 | 50.0% | 60.0% | |
| 42.86% | 7 | 6.2 | 733 | 12,293 | 40.0% | 50.0% | |
| 71.43% | 7 | 7.2 | 888 | 12,300 | 100.0% | 50.0% | |
| 57.14% | 7 | 4.0 | 760 | 10,750 | 33.3% | 75.0% | |
| 28.57% | 7 | 4.5 | 676 | 12,046 | 0.0% | 40.0% | |
| 71.43% | 7 | 3.6 | 743 | 11,425 | 80.0% | 50.0% | |
| 42.86% | 7 | 5.6 | 531 | 9,799 | 50.0% | 33.3% | |
| 42.86% | 7 | 4.5 | 723 | 11,697 | 33.3% | 50.0% | |
| 33.33% | 6 | 2.9 | 989 | 12,898 | 33.3% | 33.3% | |
| 66.67% | 6 | 7.5 | 553 | 10,627 | 80.0% | 0.0% | |
| 40.00% | 5 | 5.9 | 962 | 13,248 | 0.0% | 50.0% | |
| 60.00% | 5 | 2.5 | 883 | 15,147 | 0.0% | 75.0% | |
| 20.00% | 5 | 2.3 | 770 | 13,169 | 50.0% | 0.0% | |
| 40.00% | 5 | 7.0 | 874 | 15,053 | 0.0% | 50.0% | |
| 80.00% | 5 | 7.0 | 1,012 | 13,950 | 50.0% | 100.0% | |
| 80.00% | 5 | 6.2 | 1,024 | 13,762 | 100.0% | 66.7% | |
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Vayne vs Karma - Frequently Asked Questions
How does Vayne do against Karma in League of Legends?
Karma wins the Vayne vs Karma matchup with a 57.1% win rate compared to Vayne's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.11.
How does Vayne do against Karma in the early game?
In the early game, Vayne has the advantage against Karma with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Karma in the late game?
In the late game, Karma takes over the Vayne vs Karma matchup with a 66.7% win rate compared to 33.3%. Karma scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Karma matchup?
Karma wins the matchup against Vayne with a 57.1% win rate in League of Legends patch 26.11. The 14.3 percentage point advantage means Karma is significantly favored in this lane matchup based on 7 games analyzed.
What is the best Vayne build against Karma?
The best Vayne build against Karma includes Voltaic Cyclosword, Umbral Glaive, Bastionbreaker with Slightly Magical Footwear. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Karma?
The best Vayne runes against Karma use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Karma matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Karma?
No, Vayne struggles against Karma with only a 42.9% win rate. Karma has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Karma's lead.
How do I play Vayne against Karma?
When playing Vayne against Karma, play cautiously and avoid Karma's power spikes. Look for jungle assistance and team-dependent plays since Karma has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.