
Karmavs Vex
Karma vs Vex is a decisive matchup in LoL patch 26.7. Karma wins with a 100.0% win rate (+100.0%) over Vex based on 6 games. Karma holds the advantage in both the early and late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Vex matchup.
Karma Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Karma vs Vex Matchup?

Karma vs Vex Matchup Summary
The Karma vs Vex matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Karma wins with a 100.0% win rate compared to Vex's 0.0%, giving Karma a 100.0 percentage point advantage. Karma dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vex players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Karma leads by 288 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Karma players can confidently pick into Vex and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vex away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karma vs Vex Laning Phase Breakdown
Karma is favored during the laning phase against Vex, winning 4 out of 5 key stat categories. Karma holds advantages in damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.
Best Karma Build Against Vex
Ionian Boots of Lucidity is the optimal boots choice against Vex, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Vex are Ardent Censer, Cryptbloom and Malignance. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vex. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Vex matchup.
Early Game vs Late Game
Karma dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vex. This lopsided early game means Karma can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Karma is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vex. Extended games heavily favor Karma, whose kit and scaling make them a dominant force in team fights and objective control.
Karma holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vex players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Karma Runes Against Vex
Running Domination primary with Sorcery secondary allows Karma to press their advantage against Vex, amplifying the strengths that make this a favorable matchup.
Karma matchup data for League of Legends patch 26.7. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 43.75% | 256 | 1.2 | 373 | 8,550 | 43.9% | 43.6% | |
| 46.54% | 159 | 1.3 | 393 | 8,726 | 47.0% | 46.2% | |
| 58.06% | 155 | 1.4 | 395 | 8,985 | 51.5% | 62.9% | |
| 53.24% | 139 | 1.1 | 371 | 8,588 | 50.8% | 55.4% | |
| 48.55% | 138 | 1.3 | 366 | 8,616 | 49.3% | 47.9% | |
| 45.04% | 131 | 1.2 | 373 | 8,615 | 47.6% | 42.6% | |
| 53.10% | 113 | 1.2 | 352 | 8,429 | 54.7% | 51.7% | |
| 50.93% | 108 | 1.2 | 338 | 8,545 | 53.3% | 49.2% | |
| 43.93% | 107 | 1.2 | 422 | 8,074 | 42.9% | 45.1% | |
| 48.08% | 104 | 1.4 | 366 | 8,871 | 47.9% | 48.2% | |
| 54.00% | 100 | 1.2 | 401 | 8,426 | 59.2% | 49.0% | |
| 55.56% | 99 | 1.2 | 369 | 8,786 | 48.8% | 60.3% | |
| 46.88% | 96 | 1.1 | 394 | 8,369 | 41.5% | 53.5% | |
| 46.34% | 82 | 1.1 | 349 | 8,394 | 37.2% | 56.4% | |
| 50.00% | 66 | 1.3 | 444 | 8,645 | 65.6% | 35.3% | |
| 47.62% | 63 | 1.2 | 314 | 8,072 | 42.4% | 53.3% | |
| 40.32% | 62 | 1.3 | 345 | 8,506 | 36.7% | 43.8% | |
| 60.66% | 61 | 1.3 | 359 | 8,593 | 73.3% | 48.4% | |
| 50.00% | 58 | 1.1 | 339 | 8,723 | 63.0% | 38.7% | |
| 44.44% | 54 | 1.2 | 404 | 9,262 | 38.1% | 48.5% | |
| 57.69% | 52 | 1.3 | 523 | 9,049 | 55.6% | 60.0% | |
| 62.75% | 51 | 1.2 | 360 | 8,653 | 75.0% | 51.9% | |
| 55.32% | 47 | 1.3 | 408 | 9,914 | 58.8% | 53.3% | |
| 61.70% | 47 | 1.1 | 355 | 8,278 | 60.0% | 63.6% | |
| 53.33% | 45 | 1.2 | 408 | 8,844 | 47.6% | 58.3% | |
| 59.52% | 42 | 1.2 | 398 | 8,959 | 62.5% | 55.6% | |
| 65.85% | 41 | 1.5 | 354 | 9,179 | 53.3% | 73.1% | |
| 42.50% | 40 | 1.1 | 404 | 8,634 | 36.4% | 50.0% | |
| 41.03% | 39 | 1.2 | 356 | 8,278 | 50.0% | 29.4% | |
| 34.29% | 35 | 1.2 | 364 | 9,057 | 27.3% | 37.5% | |
| 48.48% | 33 | 1.6 | 406 | 8,880 | 44.4% | 53.3% | |
| 53.13% | 32 | 1.1 | 342 | 9,069 | 63.6% | 47.6% | |
| 50.00% | 22 | 1.1 | 359 | 8,348 | 46.1% | 55.6% | |
| 35.00% | 20 | 1.2 | 352 | 9,123 | 25.0% | 41.7% | |
| 47.37% | 19 | 1.5 | 452 | 9,262 | 60.0% | 33.3% | |
| 36.84% | 19 | 1.2 | 393 | 8,198 | 33.3% | 40.0% | |
| 57.89% | 19 | 1.5 | 377 | 8,143 | 77.8% | 40.0% | |
| 64.29% | 14 | 2.4 | 442 | 9,749 | 83.3% | 50.0% | |
| 64.29% | 14 | 3.1 | 550 | 9,957 | 57.1% | 71.4% | |
| 42.86% | 14 | 1.7 | 429 | 8,781 | 50.0% | 37.5% | |
| 46.15% | 13 | 1.1 | 369 | 8,593 | 60.0% | 37.5% | |
| 69.23% | 13 | 1.3 | 307 | 8,717 | 62.5% | 80.0% | |
| 58.33% | 12 | 1.9 | 360 | 9,126 | 40.0% | 71.4% | |
| 41.67% | 12 | 1.3 | 456 | 10,296 | 25.0% | 50.0% | |
| 66.67% | 12 | 1.7 | 362 | 8,499 | 66.7% | 66.7% | |
| 36.36% | 11 | 3.1 | 656 | 10,863 | 40.0% | 33.3% | |
| 72.73% | 11 | 2.9 | 519 | 8,643 | 83.3% | 60.0% | |
| 80.00% | 10 | 1.9 | 541 | 9,264 | 83.3% | 75.0% | |
| 30.00% | 10 | 1.4 | 390 | 8,784 | 40.0% | 20.0% | |
| 50.00% | 8 | 6.0 | 719 | 9,336 | 50.0% | 50.0% | |
| 50.00% | 8 | 3.9 | 722 | 9,604 | 33.3% | 60.0% | |
| 75.00% | 8 | 5.3 | 617 | 8,713 | 50.0% | 100.0% | |
| 71.43% | 7 | 1.8 | 486 | 9,662 | 50.0% | 100.0% | |
| 71.43% | 7 | 1.5 | 292 | 9,606 | 66.7% | 75.0% | |
| 16.67% | 6 | 5.7 | 577 | 10,715 | 33.3% | 0.0% | |
| 66.67% | 6 | 3.9 | 660 | 10,346 | 66.7% | 66.7% | |
| 100.00% | 6 | 4.2 | 643 | 10,637 | 100.0% | 100.0% | |
| 50.00% | 6 | 5.6 | 753 | 11,034 | 50.0% | 50.0% | |
| 33.33% | 6 | 6.8 | 800 | 11,202 | 50.0% | 0.0% | |
| 80.00% | 5 | 3.6 | 705 | 9,639 | 75.0% | 100.0% | |
| 60.00% | 5 | 4.9 | 758 | 11,254 | 100.0% | 50.0% | |
| 20.00% | 5 | 3.8 | 572 | 11,437 | 50.0% | 0.0% | |
| 80.00% | 5 | 2.5 | 597 | 10,949 | 100.0% | 66.7% | |
| 40.00% | 5 | 3.8 | 542 | 7,186 | 40.0% | 0.0% | |
| 40.00% | 5 | 5.8 | 756 | 10,060 | 0.0% | 66.7% | |
| 60.00% | 5 | 1.9 | 408 | 11,435 | 0.0% | 60.0% | |
| 80.00% | 5 | 2.0 | 546 | 8,174 | 66.7% | 100.0% | |
| 100.00% | 5 | 3.9 | 718 | 9,815 | 100.0% | 0.0% | |
| 60.00% | 5 | 3.9 | 569 | 12,055 | 100.0% | 50.0% | |
| 40.00% | 5 | 2.7 | 455 | 9,204 | 33.3% | 50.0% | |
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Karma vs Vex - Frequently Asked Questions
How does Karma do against Vex in League of Legends?
Karma wins the Karma vs Vex matchup with a 100.0% win rate compared to Vex's 0.0%, a 100.0 percentage point difference. This data is based on 6 recent ranked games in patch 26.7.
How does Karma do against Vex in the early game?
In the early game, Karma has the advantage against Vex with a 100.0% win rate versus 0.0%. Karma players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karma do against Vex in the late game?
In the late game, Karma takes over the Karma vs Vex matchup with a 100.0% win rate compared to 0.0%. Karma scales better into team fights and objective contests after 25 minutes.
Who wins the Karma vs Vex matchup?
Karma wins the matchup against Vex with a 100.0% win rate in League of Legends patch 26.7. The 100.0 percentage point advantage means Karma is significantly favored in this lane matchup based on 6 games analyzed.
What is the best Karma build against Vex?
The best Karma build against Vex includes Ardent Censer, Cryptbloom, Malignance with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Karma runes against Vex?
The best Karma runes against Vex use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Karma vs Vex matchup. See the full rune breakdown in the matchup comparison above.
Does Karma counter Vex?
Yes, Karma has a favorable matchup against Vex with a 100.0% win rate. Karma strongly counters Vex in lane based on current patch 26.7 data.
How do I play Karma against Vex?
When playing Karma against Vex, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
