
Karmavs Lissandra
Karma vs Lissandra is a decisive matchup in LoL patch 26.7. Lissandra wins with a 80.0% win rate (+60.0%) over Karma based on 5 games. Karma wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Lissandra matchup.
Karma Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Karma vs Lissandra Matchup?

Karma vs Lissandra Matchup Summary
The Karma vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Lissandra wins with a 80.0% win rate compared to Karma's 20.0%, giving Lissandra a 60.0 percentage point advantage. Game phase dynamics play a critical role here: Karma controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karma needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Karma leads by 352 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Karma players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Karma vs Lissandra Laning Phase Breakdown
Lissandra is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Karma Build Against Lissandra
Ionian Boots of Lucidity is the optimal boots choice against Lissandra, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Lissandra are Echoes of Helia, Moonstone Renewer and Mikael's Blessing. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Lissandra matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Karma and Lissandra, with Karma holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Lissandra is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karma. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.
The power dynamics shift as the game progresses — Karma has the edge early, but Lissandra gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.
Best Karma Runes Against Lissandra
The Sorcery and Resolve rune setup gives Karma the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Karma matchup data for League of Legends patch 26.7. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 43.75% | 256 | 1.2 | 373 | 8,550 | 43.9% | 43.6% | |
| 46.54% | 159 | 1.3 | 393 | 8,726 | 47.0% | 46.2% | |
| 58.06% | 155 | 1.4 | 395 | 8,985 | 51.5% | 62.9% | |
| 53.24% | 139 | 1.1 | 371 | 8,588 | 50.8% | 55.4% | |
| 48.55% | 138 | 1.3 | 366 | 8,616 | 49.3% | 47.9% | |
| 45.04% | 131 | 1.2 | 373 | 8,615 | 47.6% | 42.6% | |
| 53.10% | 113 | 1.2 | 352 | 8,429 | 54.7% | 51.7% | |
| 50.93% | 108 | 1.2 | 338 | 8,545 | 53.3% | 49.2% | |
| 43.93% | 107 | 1.2 | 422 | 8,074 | 42.9% | 45.1% | |
| 48.08% | 104 | 1.4 | 366 | 8,871 | 47.9% | 48.2% | |
| 54.00% | 100 | 1.2 | 401 | 8,426 | 59.2% | 49.0% | |
| 55.56% | 99 | 1.2 | 369 | 8,786 | 48.8% | 60.3% | |
| 46.88% | 96 | 1.1 | 394 | 8,369 | 41.5% | 53.5% | |
| 46.34% | 82 | 1.1 | 349 | 8,394 | 37.2% | 56.4% | |
| 50.00% | 66 | 1.3 | 444 | 8,645 | 65.6% | 35.3% | |
| 47.62% | 63 | 1.2 | 314 | 8,072 | 42.4% | 53.3% | |
| 40.32% | 62 | 1.3 | 345 | 8,506 | 36.7% | 43.8% | |
| 60.66% | 61 | 1.3 | 359 | 8,593 | 73.3% | 48.4% | |
| 50.00% | 58 | 1.1 | 339 | 8,723 | 63.0% | 38.7% | |
| 44.44% | 54 | 1.2 | 404 | 9,262 | 38.1% | 48.5% | |
| 57.69% | 52 | 1.3 | 523 | 9,049 | 55.6% | 60.0% | |
| 62.75% | 51 | 1.2 | 360 | 8,653 | 75.0% | 51.9% | |
| 55.32% | 47 | 1.3 | 408 | 9,914 | 58.8% | 53.3% | |
| 61.70% | 47 | 1.1 | 355 | 8,278 | 60.0% | 63.6% | |
| 53.33% | 45 | 1.2 | 408 | 8,844 | 47.6% | 58.3% | |
| 59.52% | 42 | 1.2 | 398 | 8,959 | 62.5% | 55.6% | |
| 65.85% | 41 | 1.5 | 354 | 9,179 | 53.3% | 73.1% | |
| 42.50% | 40 | 1.1 | 404 | 8,634 | 36.4% | 50.0% | |
| 41.03% | 39 | 1.2 | 356 | 8,278 | 50.0% | 29.4% | |
| 34.29% | 35 | 1.2 | 364 | 9,057 | 27.3% | 37.5% | |
| 48.48% | 33 | 1.6 | 406 | 8,880 | 44.4% | 53.3% | |
| 53.13% | 32 | 1.1 | 342 | 9,069 | 63.6% | 47.6% | |
| 50.00% | 22 | 1.1 | 359 | 8,348 | 46.1% | 55.6% | |
| 35.00% | 20 | 1.2 | 352 | 9,123 | 25.0% | 41.7% | |
| 47.37% | 19 | 1.5 | 452 | 9,262 | 60.0% | 33.3% | |
| 36.84% | 19 | 1.2 | 393 | 8,198 | 33.3% | 40.0% | |
| 57.89% | 19 | 1.5 | 377 | 8,143 | 77.8% | 40.0% | |
| 64.29% | 14 | 2.4 | 442 | 9,749 | 83.3% | 50.0% | |
| 64.29% | 14 | 3.1 | 550 | 9,957 | 57.1% | 71.4% | |
| 42.86% | 14 | 1.7 | 429 | 8,781 | 50.0% | 37.5% | |
| 46.15% | 13 | 1.1 | 369 | 8,593 | 60.0% | 37.5% | |
| 69.23% | 13 | 1.3 | 307 | 8,717 | 62.5% | 80.0% | |
| 58.33% | 12 | 1.9 | 360 | 9,126 | 40.0% | 71.4% | |
| 41.67% | 12 | 1.3 | 456 | 10,296 | 25.0% | 50.0% | |
| 66.67% | 12 | 1.7 | 362 | 8,499 | 66.7% | 66.7% | |
| 36.36% | 11 | 3.1 | 656 | 10,863 | 40.0% | 33.3% | |
| 72.73% | 11 | 2.9 | 519 | 8,643 | 83.3% | 60.0% | |
| 80.00% | 10 | 1.9 | 541 | 9,264 | 83.3% | 75.0% | |
| 30.00% | 10 | 1.4 | 390 | 8,784 | 40.0% | 20.0% | |
| 50.00% | 8 | 6.0 | 719 | 9,336 | 50.0% | 50.0% | |
| 50.00% | 8 | 3.9 | 722 | 9,604 | 33.3% | 60.0% | |
| 75.00% | 8 | 5.3 | 617 | 8,713 | 50.0% | 100.0% | |
| 71.43% | 7 | 1.8 | 486 | 9,662 | 50.0% | 100.0% | |
| 71.43% | 7 | 1.5 | 292 | 9,606 | 66.7% | 75.0% | |
| 16.67% | 6 | 5.7 | 577 | 10,715 | 33.3% | 0.0% | |
| 66.67% | 6 | 3.9 | 660 | 10,346 | 66.7% | 66.7% | |
| 100.00% | 6 | 4.2 | 643 | 10,637 | 100.0% | 100.0% | |
| 50.00% | 6 | 5.6 | 753 | 11,034 | 50.0% | 50.0% | |
| 33.33% | 6 | 6.8 | 800 | 11,202 | 50.0% | 0.0% | |
| 80.00% | 5 | 3.6 | 705 | 9,639 | 75.0% | 100.0% | |
| 60.00% | 5 | 4.9 | 758 | 11,254 | 100.0% | 50.0% | |
| 20.00% | 5 | 3.8 | 572 | 11,437 | 50.0% | 0.0% | |
| 80.00% | 5 | 2.5 | 597 | 10,949 | 100.0% | 66.7% | |
| 40.00% | 5 | 3.8 | 542 | 7,186 | 40.0% | 0.0% | |
| 40.00% | 5 | 5.8 | 756 | 10,060 | 0.0% | 66.7% | |
| 60.00% | 5 | 1.9 | 408 | 11,435 | 0.0% | 60.0% | |
| 80.00% | 5 | 2.0 | 546 | 8,174 | 66.7% | 100.0% | |
| 100.00% | 5 | 3.9 | 718 | 9,815 | 100.0% | 0.0% | |
| 60.00% | 5 | 3.9 | 569 | 12,055 | 100.0% | 50.0% | |
| 40.00% | 5 | 2.7 | 455 | 9,204 | 33.3% | 50.0% | |
Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.
Karma vs Lissandra - Frequently Asked Questions
How does Karma do against Lissandra in League of Legends?
Lissandra wins the Karma vs Lissandra matchup with a 80.0% win rate compared to Karma's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.7.
How does Karma do against Lissandra in the early game?
In the early game, Karma has the advantage against Lissandra with a 50.0% win rate versus 50.0%. Karma players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Karma do against Lissandra in the late game?
In the late game, Lissandra takes over the Karma vs Lissandra matchup with a 100.0% win rate compared to 0.0%. Lissandra scales better into team fights and objective contests after 25 minutes.
Who wins the Karma vs Lissandra matchup?
Lissandra wins the matchup against Karma with a 80.0% win rate in League of Legends patch 26.7. The 60.0 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Karma build against Lissandra?
The best Karma build against Lissandra includes Echoes of Helia, Moonstone Renewer, Mikael's Blessing with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.
What are the best Karma runes against Lissandra?
The best Karma runes against Lissandra use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Karma vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.
Does Karma counter Lissandra?
No, Karma struggles against Lissandra with only a 20.0% win rate. Lissandra has the advantage in this matchup. Karma players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.
How do I play Karma against Lissandra?
When playing Karma against Lissandra, play cautiously and avoid Lissandra's power spikes. Look for jungle assistance and team-dependent plays since Lissandra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.