Karma - League of Legends Champion
Win Rate
50.2%
Pick Rate
3.2%

Karmavs Lissandra

BMageSupport
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 22, 2026
MethodologyData Methodology

Karma vs Lissandra is a decisive matchup in LoL patch 26.7. Lissandra wins with a 80.0% win rate (+60.0%) over Karma based on 5 games. Karma wins the early laning phase while Lissandra scales better into the late game. Below you'll find the best Karma build, runes, laning stats, and strategies for the Karma vs Lissandra matchup.

Karma Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karma performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 20.0% win rateLissandra(20.0%)
Karma - 20.0% win rate in this matchup
Karma
20.0% WR
VS
Lissandra vs Karma matchup - 80.0% win rate
Lissandra
80.0% WR

Who Wins the Karma vs Lissandra Matchup?

Lissandra wins the Karma vs Lissandra matchup
Winner
Lissandra
Matches: 5
20.0%
Win Rate
80.0%
3.8
CS / min
5.0
572
DMG / min
647
11,437
Gold / game
12,918
286
Heal / min
156
683
DMG Mitigated / min
460
1.1
CC / min
1.6
50.0%
Early Game WR
50.0%
0.0%
Late Game WR
100.0%

Karma vs Lissandra Matchup Summary

The Karma vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Lissandra wins with a 80.0% win rate compared to Karma's 20.0%, giving Lissandra a 60.0 percentage point advantage. Game phase dynamics play a critical role here: Karma controls the early laning stage, but Lissandra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karma needs to press advantages before Lissandra reaches their power spikes, while Lissandra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Karma leads by 352 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra has a strong advantage in this matchup. Karma players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Lissandra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karma vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Karma in League of Legends

Lissandra is favored during the laning phase against Karma, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
3.8Karma
5.0Lissandra
Lissandra significantly out-farms Karma by 1.2 CS per minute, accumulating an estimated 18 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Karma players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
572Karma
647Lissandra
Lissandra deals 75 more champion damage per minute than Karma. While noticeable in extended trades, this gap can be offset by Karma choosing favorable fight windows, such as engaging when Lissandra's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
11,437Karma
12,918Lissandra
Lissandra generates a commanding 1,481 more gold per game than Karma. This substantial economic advantage means Lissandra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karma should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.1Karma
1.6Lissandra
Lissandra provides 0.5 seconds more crowd control per minute than Karma, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
968Karma
616Lissandra
Karma vastly out-sustains Lissandra, healing and mitigating 352 more damage per minute. This massive durability gap means Karma can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karma Build Against Lissandra

Ionian Boots of Lucidity is the optimal boots choice against Lissandra, providing the mobility and stats Karma needs most in this matchup. The top-performing core items for Karma against Lissandra are Echoes of Helia, Moonstone Renewer and Mikael's Blessing. This combination gives Karma an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karma vs Lissandra matchup.

Early Game vs Late Game

Early Game
Karma
50.0%
+0.0% advantage
Karma early game win rateKarma50.0%
Lissandra early game win rateLissandra50.0%
Late Game
Lissandra
100.0%
+100.0% advantage
Karma late game win rateKarma0.0%
Lissandra late game win rateLissandra100.0%

The early game (first 15 minutes) is a toss-up between Karma and Lissandra, with Karma holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Lissandra is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karma. Extended games heavily favor Lissandra, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Karma has the edge early, but Lissandra gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Karma Runes Against Lissandra

Sorcery rune tree - Karma primary runes vs LissandraSorcery
Summon Aery - best Karma rune vs LissandraManaflow Band - best Karma rune vs LissandraTranscendence - best Karma rune vs LissandraGathering Storm - best Karma rune vs Lissandra
Resolve rune tree - Karma secondary runes vs LissandraResolve
Font of Life - best Karma rune vs LissandraRevitalize - best Karma rune vs Lissandra
100.0% WR

The Sorcery and Resolve rune setup gives Karma the best tools to compete against Lissandra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Karma matchup data for League of Legends patch 26.7. The table below shows Karma's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karma build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karma matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
43.75%2561.23738,55043.9%43.6%
46.54%1591.33938,72647.0%46.2%
58.06%1551.43958,98551.5%62.9%
53.24%1391.13718,58850.8%55.4%
48.55%1381.33668,61649.3%47.9%
45.04%1311.23738,61547.6%42.6%
53.10%1131.23528,42954.7%51.7%
50.93%1081.23388,54553.3%49.2%
43.93%1071.24228,07442.9%45.1%
48.08%1041.43668,87147.9%48.2%
54.00%1001.24018,42659.2%49.0%
55.56%991.23698,78648.8%60.3%
46.88%961.13948,36941.5%53.5%
46.34%821.13498,39437.2%56.4%
50.00%661.34448,64565.6%35.3%
47.62%631.23148,07242.4%53.3%
40.32%621.33458,50636.7%43.8%
60.66%611.33598,59373.3%48.4%
50.00%581.13398,72363.0%38.7%
44.44%541.24049,26238.1%48.5%
57.69%521.35239,04955.6%60.0%
62.75%511.23608,65375.0%51.9%
55.32%471.34089,91458.8%53.3%
61.70%471.13558,27860.0%63.6%
53.33%451.24088,84447.6%58.3%
59.52%421.23988,95962.5%55.6%
65.85%411.53549,17953.3%73.1%
42.50%401.14048,63436.4%50.0%
41.03%391.23568,27850.0%29.4%
34.29%351.23649,05727.3%37.5%
48.48%331.64068,88044.4%53.3%
53.13%321.13429,06963.6%47.6%
50.00%221.13598,34846.1%55.6%
35.00%201.23529,12325.0%41.7%
47.37%191.54529,26260.0%33.3%
36.84%191.23938,19833.3%40.0%
57.89%191.53778,14377.8%40.0%
64.29%142.44429,74983.3%50.0%
64.29%143.15509,95757.1%71.4%
42.86%141.74298,78150.0%37.5%
46.15%131.13698,59360.0%37.5%
69.23%131.33078,71762.5%80.0%
58.33%121.93609,12640.0%71.4%
41.67%121.345610,29625.0%50.0%
66.67%121.73628,49966.7%66.7%
36.36%113.165610,86340.0%33.3%
72.73%112.95198,64383.3%60.0%
80.00%101.95419,26483.3%75.0%
30.00%101.43908,78440.0%20.0%
50.00%86.07199,33650.0%50.0%
50.00%83.97229,60433.3%60.0%
75.00%85.36178,71350.0%100.0%
71.43%71.84869,66250.0%100.0%
71.43%71.52929,60666.7%75.0%
16.67%65.757710,71533.3%0.0%
66.67%63.966010,34666.7%66.7%
100.00%64.264310,637100.0%100.0%
50.00%65.675311,03450.0%50.0%
33.33%66.880011,20250.0%0.0%
80.00%53.67059,63975.0%100.0%
60.00%54.975811,254100.0%50.0%
20.00%53.857211,43750.0%0.0%
80.00%52.559710,949100.0%66.7%
40.00%53.85427,18640.0%0.0%
40.00%55.875610,0600.0%66.7%
60.00%51.940811,4350.0%60.0%
80.00%52.05468,17466.7%100.0%
100.00%53.97189,815100.0%0.0%
60.00%53.956912,055100.0%50.0%
40.00%52.74559,20433.3%50.0%

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Karma vs Lissandra - Frequently Asked Questions

How does Karma do against Lissandra in League of Legends?

Lissandra wins the Karma vs Lissandra matchup with a 80.0% win rate compared to Karma's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.7.

How does Karma do against Lissandra in the early game?

In the early game, Karma has the advantage against Lissandra with a 50.0% win rate versus 50.0%. Karma players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karma do against Lissandra in the late game?

In the late game, Lissandra takes over the Karma vs Lissandra matchup with a 100.0% win rate compared to 0.0%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Karma vs Lissandra matchup?

Lissandra wins the matchup against Karma with a 80.0% win rate in League of Legends patch 26.7. The 60.0 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Karma build against Lissandra?

The best Karma build against Lissandra includes Echoes of Helia, Moonstone Renewer, Mikael's Blessing with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Karma runes against Lissandra?

The best Karma runes against Lissandra use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Karma vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Karma counter Lissandra?

No, Karma struggles against Lissandra with only a 20.0% win rate. Lissandra has the advantage in this matchup. Karma players should focus on safe farming and avoiding extended trades to minimize Lissandra's lead.

How do I play Karma against Lissandra?

When playing Karma against Lissandra, play cautiously and avoid Lissandra's power spikes. Look for jungle assistance and team-dependent plays since Lissandra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.