Lissandra - League of Legends Champion
Win Rate
48.6%
Pick Rate
1.8%

Lissandravs Yasuo

DMage
Patch26.12
Matches112,472
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 15, 2026
MethodologyData Methodology

Lissandra vs Yasuo is a decisive matchup in LoL patch 26.12. Yasuo wins with a 52.6% win rate (+5.3%) over Lissandra based on 19 games. Yasuo holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Yasuo matchup.

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Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 47.4% win rate in this matchup
Lissandra
47.4% WR
VS
Yasuo vs Lissandra matchup - 52.6% win rate
Yasuo
52.6% WR

Who Wins the Lissandra vs Yasuo Matchup?

Yasuo wins the Lissandra vs Yasuo matchup
Winner
Yasuo
Matches: 19
47.4%
Win Rate
52.6%
6.8
CS / min
7.1
763
DMG / min
759
11,614
Gold / game
12,300
135
Heal / min
232
455
DMG Mitigated / min
1,059
1.9
CC / min
0.8
50.0%
Early Game WR
55.6%
45.5%
Late Game WR
50.0%

Lissandra vs Yasuo Matchup Summary

The Lissandra vs Yasuo matchup is a moderate matchup in League of Legends ranked play. Based on 19 recent matches analyzed, Yasuo wins with a 52.6% win rate compared to Lissandra's 47.4%, giving Yasuo a 5.3 percentage point advantage. Yasuo dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. While Yasuo is slightly favored, Lissandra can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Yasuo's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Yasuo Laning Phase Breakdown

Yasuo wins the laning phase against Lissandra in League of Legends

Yasuo is favored during the laning phase against Lissandra, winning 3 out of 5 key stat categories. Yasuo holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
6.8Lissandra
7.1Yasuo
Lissandra and Yasuo farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
763Lissandra
759Yasuo
Damage output is virtually even between Lissandra and Yasuo, with only 4 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
11,614Lissandra
12,300Yasuo
Yasuo earns 685 more gold per game than Lissandra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Yasuo slightly faster item completions.
Utility
1.9Lissandra
0.8Yasuo
Lissandra brings significantly more crowd control than Yasuo, with 1.1 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Yasuo should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
590Lissandra
1,291Yasuo
Yasuo vastly out-sustains Lissandra, healing and mitigating 701 more damage per minute. This massive durability gap means Yasuo can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Yasuo

Spellslinger's Shoes is the optimal boots choice against Yasuo, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Yasuo are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 3 games — well above average and making it the top item path against Yasuo. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Yasuo matchup.

Early Game vs Late Game

Early Game
Yasuo
55.6%
+5.6% advantage
Lissandra early game win rateLissandra50.0%
Yasuo early game win rateYasuo55.6%
Late Game
Yasuo
50.0%
+4.5% advantage
Lissandra late game win rateLissandra45.5%
Yasuo late game win rateYasuo50.0%

Yasuo dominates the early game (first 15 minutes) with a commanding 55.6% win rate — a 5.6 percentage point lead over Lissandra. This lopsided early game means Yasuo can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

In the late game (25+ minutes), Yasuo takes over with a 50.0% win rate, leading Lissandra by 4.5 percentage points. Yasuo scales more effectively into team fights and objective contests.

Yasuo holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Yasuo

Domination rune tree - Lissandra primary runes vs YasuoDomination
Electrocute - best Lissandra rune vs YasuoCheap Shot - best Lissandra rune vs YasuoSixth Sense - best Lissandra rune vs YasuoUltimate Hunter - best Lissandra rune vs Yasuo
Sorcery rune tree - Lissandra secondary runes vs YasuoSorcery
Transcendence - best Lissandra rune vs YasuoGathering Storm - best Lissandra rune vs Yasuo
100.0% WR

The Domination and Sorcery rune setup gives Lissandra the best tools to compete against Yasuo in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.12. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.12
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.37%196.876311,61450.0%45.5%
36.84%196.869311,45225.0%45.5%
41.18%176.583212,64937.5%44.4%
58.82%176.798713,14650.0%63.6%
60.00%156.989911,29885.7%37.5%
61.54%136.985112,115100.0%28.6%
38.46%135.765311,13240.0%37.5%
50.00%127.283812,37757.1%40.0%
45.45%117.486511,63242.9%50.0%
60.00%106.982512,01140.0%80.0%
70.00%106.789014,197100.0%50.0%
22.22%96.56929,96820.0%25.0%
44.44%96.792211,67540.0%50.0%
37.50%86.71,11612,92850.0%33.3%
50.00%86.777212,15350.0%50.0%
85.71%76.790612,32680.0%100.0%
71.43%77.983712,25780.0%50.0%
71.43%75.674611,10066.7%75.0%
50.00%66.485911,17266.7%33.3%
83.33%67.288011,938100.0%0.0%
33.33%66.364811,02733.3%33.3%
33.33%67.081512,90533.3%33.3%
50.00%66.787413,572100.0%40.0%
33.33%67.282710,94133.3%33.3%
20.00%52.54529,24025.0%0.0%
60.00%56.95258,94233.3%100.0%
20.00%57.193812,3590.0%50.0%
60.00%57.31,07213,24466.7%50.0%
40.00%56.57079,99266.7%0.0%
40.00%57.058610,273100.0%0.0%
66.67%36.91,10313,061100.0%0.0%
50.00%25.45268,70650.0%0.0%
50.00%26.149311,3460.0%50.0%
50.00%25.589610,957100.0%0.0%

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Lissandra vs Yasuo - Frequently Asked Questions

How does Lissandra do against Yasuo in League of Legends?

Yasuo wins the Lissandra vs Yasuo matchup with a 52.6% win rate compared to Lissandra's 47.4%, a 5.3 percentage point difference. This data is based on 19 recent ranked games in patch 26.12.

How does Lissandra do against Yasuo in the early game?

In the early game, Yasuo has the advantage against Lissandra with a 55.6% win rate versus 50.0%. Yasuo players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Yasuo in the late game?

In the late game, Yasuo takes over the Lissandra vs Yasuo matchup with a 50.0% win rate compared to 45.5%. Yasuo scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Yasuo matchup?

Yasuo wins the matchup against Lissandra with a 52.6% win rate in League of Legends patch 26.12. The 5.3 percentage point advantage means Yasuo is significantly favored in this lane matchup based on 19 games analyzed.

What is the best Lissandra build against Yasuo?

The best Lissandra build against Yasuo includes Shadowflame, Zhonya's Hourglass, Malignance with Spellslinger's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Yasuo?

The best Lissandra runes against Yasuo use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Yasuo matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Yasuo?

No, Lissandra struggles against Yasuo with only a 47.4% win rate. Yasuo has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Yasuo's lead.

How do I play Lissandra against Yasuo?

When playing Lissandra against Yasuo, play cautiously and avoid Yasuo's power spikes. Look for jungle assistance and team-dependent plays since Yasuo has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.