Miss Fortune - League of Legends Champion
Win Rate
50.7%
Pick Rate
7.1%

Miss FortuneRunes

BMarksmanMage
Patch26.12
Matches157,752
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 17, 2026
MethodologyData Methodology

Best Miss Fortune runes for LoL Patch 26.12 - First Strike from the Inspiration tree with Sorcery secondary (56.5% WR, 1.0% pick rate). Miss Fortune's optimal primary runes are First Strike, Cash Back, Biscuit Delivery, Jack Of All Trades. Secondary tree: Manaflow Band, Gathering Storm.

Metabot Logo
MetaBot Desktop
Live In-Game Overlays
Join Our Discord
Bug reports, feature requests & developer chat
Join Discord
Miss Fortune performs best with First Strike as the keystone rune from the Inspiration tree. Miss Fortune's optimal primary runes are First Strike, Cash Back, Biscuit Delivery, Jack Of All Trades. Miss Fortune's secondary rune tree is Sorcery with Manaflow Band, Gathering Storm. This rune setup achieves a 56.52% win rate (+5.8% win rate difference) with a 1.0% pick rate across 23 Miss Fortune games.
56.5%Win Rate
+5.8%WR Diff
1.0%Pick Rate
First StrikeFirst Strike

Attacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 50% (35% for ranged champions) of bonus damage dealt as gold.

Cooldown: 25 - 15s

Cash BackCash Back

Get 7.5% Gold back when you purchase Legendary Items.

Biscuit DeliveryBiscuit Delivery

Biscuit Delivery: Gain a Total Biscuit of Everlasting Will every 2 mins, until 6 min.

Biscuits restore 20 + 2% of your maximum health, increased by up to 100% based on missing Health. Consuming or selling a Biscuit permanently increases your max health by 30.

Jack Of All TradesJack Of All Trades

For each different stat gained from items, gain one Jack stack. Each stack grants you 1 Ability Haste.

Gain 10 or 25 bonus Adaptive Force at 5 and 10 stacks, respectively.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

Gathering StormGathering Storm

Every 10 min gain AP or AD, adaptive.

10 min: + 8 AP or 5 AD
20 min: + 24 AP or 14 AD
30 min: + 48 AP or 29 AD
40 min: + 80 AP or 48 AD
50 min: + 120 AP or 72 AD
60 min: + 168 AP or 101 AD
etc...

This alternative Miss Fortune rune build uses Press the Attack as the keystone from the Precision tree. The primary runes are Press the Attack, Presence of Mind, Legend: Alacrity, Cut Down. Miss Fortune's secondary rune tree is Inspiration with Cash Back, Triple Tonic. This setup achieves a 56.25% win rate (+5.5% win rate difference) with a 0.7% pick rate across 16 games.
56.3%Win Rate
+5.5%WR Diff
0.7%Pick Rate
Press the AttackPress the Attack

Hitting an enemy champion with 3 consecutive basic attacks deals 40 - 160 bonus adaptive damage (based on level) and amplifies your damage dealt by 8% until you leave combat with champions.

Presence of MindPresence of Mind

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.

Takedowns restore 15% of your maximum mana or energy.

Cooldown for damage restoration: 8s

Legend: AlacrityLegend: Alacrity

Gain 3% attack speed plus an additional 1.5% for every Legend stack (max 10 stacks).

Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.

Cut DownCut Down

Deal 8% more damage to champions who have more than 60% health.

Cash BackCash Back

Get 7.5% Gold back when you purchase Legendary Items.

Triple TonicTriple Tonic

Upon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Miss Fortune Runes - Frequently Asked Questions

What are the best Miss Fortune runes in patch 26.12?

The best Miss Fortune runes in patch 26.12 use the Inspiration tree with First Strike, Cash Back, Biscuit Delivery, and Jack Of All Trades, and the Sorcery tree with Manaflow Band and Gathering Storm. This rune setup achieves a 56.5% win rate with a 1.0% pick rate.

What is the win rate for Miss Fortune's best rune page?

Miss Fortune's best rune page has a 56.5% win rate in patch 26.12, which is +5.8% compared to Miss Fortune's average win rate. This rune setup has a 1.0% pick rate among Miss Fortune players.

What keystone should I use on Miss Fortune?

First Strike from the Inspiration tree is the best keystone rune for Miss Fortune in patch 26.12. This keystone synergizes well with Miss Fortune's kit and provides a 56.5% win rate.

What is Miss Fortune's primary rune tree?

Miss Fortune's primary rune tree is Inspiration. The optimal Inspiration runes for Miss Fortune are First Strike, Cash Back, Biscuit Delivery, and Jack Of All Trades, with First Strike being the keystone of choice.

What is Miss Fortune's secondary rune tree?

Miss Fortune's best secondary rune tree is Sorcery. The recommended Sorcery runes are Manaflow Band and Gathering Storm, which complement Miss Fortune's Inspiration primary tree.

What are alternative rune setups for Miss Fortune?

An alternative Miss Fortune rune setup uses alternative keystone from the Precision tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Miss Fortune's runes?

Miss Fortune's top rune page has a 1.0% pick rate in patch 26.12. This indicates that 1.0% of Miss Fortune players use the First Strike setup with Inspiration and Sorcery trees.