Orianna - League of Legends Champion
Win Rate
47.3%
Pick Rate
1.7%

Oriannavs Karthus

FMageSupport
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Orianna vs Karthus is a decisive matchup in LoL patch 26.5. Orianna wins with a 60.0% win rate (+20.0%) over Karthus based on 5 games. Orianna holds the advantage in both the early and late game. Below you'll find the best Orianna build, runes, laning stats, and strategies for the Orianna vs Karthus matchup.

Orianna Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Orianna performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Karthus - 60.0% win rateKarthus(60.0%)
Orianna - 60.0% win rate in this matchup
Orianna
60.0% WR
VS
Karthus vs Orianna matchup - 40.0% win rate
Karthus
40.0% WR

Who Wins the Orianna vs Karthus Matchup?

Orianna wins the Orianna vs Karthus matchup
Winner
Orianna
Matches: 5
60.0%
Win Rate
40.0%
7.2
CS / min
6.4
1,279
DMG / min
1,033
15,572
Gold / game
12,247
129
Heal / min
128
628
DMG Mitigated / min
522
0.9
CC / min
0.6
100.0%
Early Game WR
0.0%
50.0%
Late Game WR
50.0%

Orianna vs Karthus Matchup Summary

The Orianna vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Orianna wins with a 60.0% win rate compared to Karthus's 40.0%, giving Orianna a 20.0 percentage point advantage. Orianna dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Karthus players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Orianna leads by 0.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Orianna players can confidently pick into Karthus and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Karthus away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Orianna vs Karthus Laning Phase Breakdown

Orianna wins the laning phase against Karthus in League of Legends

Orianna is favored during the laning phase against Karthus, winning 5 out of 5 key stat categories. Orianna holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
7.2Orianna
6.4Karthus
Orianna edges out Karthus by 0.7 CS per minute — a moderate farming advantage that adds up to roughly 11 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Orianna.
Damage
1,279Orianna
1,033Karthus
Orianna heavily out-damages Karthus by 246 DMG/min, dominating both short trades and all-in fights. Karthus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Orianna's sustained damage advantage take over.
Economy
15,572Orianna
12,247Karthus
Orianna generates a commanding 3,325 more gold per game than Karthus. This substantial economic advantage means Orianna consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Karthus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.9Orianna
0.6Karthus
Orianna provides 0.3 seconds more crowd control per minute than Karthus, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Orianna coordinate with their jungler and control the pace of skirmishes.
Sustain
757Orianna
650Karthus
Orianna heals and mitigates 106 more damage per minute than Karthus, providing moderate extra durability. This sustain edge allows Orianna to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Karthus.

Best Orianna Build Against Karthus

Crimson Lucidity is the optimal boots choice against Karthus, providing the mobility and stats Orianna needs most in this matchup. The top-performing core items for Orianna against Karthus are Luden's Echo, Shadowflame and Banshee's Veil. This combination gives Orianna an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Karthus. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Orianna vs Karthus matchup.

Early Game vs Late Game

Early Game
Orianna
100.0%
+100.0% advantage
Orianna early game win rateOrianna100.0%
Karthus early game win rateKarthus0.0%
Late Game
Orianna
50.0%
+0.0% advantage
Orianna late game win rateOrianna50.0%
Karthus late game win rateKarthus50.0%

Orianna dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Karthus. This lopsided early game means Orianna can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Orianna at 50.0% win rate — only 0.0 points ahead of Karthus. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Orianna holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Karthus players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Orianna Runes Against Karthus

Sorcery rune tree - Orianna primary runes vs KarthusSorcery
Summon Aery - best Orianna rune vs KarthusManaflow Band - best Orianna rune vs KarthusTranscendence - best Orianna rune vs KarthusScorch - best Orianna rune vs Karthus
Precision rune tree - Orianna secondary runes vs KarthusPrecision
Coup de Grace - best Orianna rune vs KarthusPresence of Mind - best Orianna rune vs Karthus
100.0% WR

Running Sorcery primary with Precision secondary allows Orianna to press their advantage against Karthus, amplifying the strengths that make this a favorable matchup.


Orianna matchup data for League of Legends patch 26.5. The table below shows Orianna's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Orianna build, runes, laning stats, and early vs late game analysis for that specific matchup.

Orianna matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
38.69%1376.981511,79836.5%40.5%
50.00%706.775811,64137.9%58.5%
37.93%587.469310,54637.0%38.7%
51.79%566.773211,76742.9%57.1%
50.00%527.070611,68647.6%51.6%
58.00%506.783011,44760.9%55.6%
46.94%496.270211,29343.8%48.5%
39.58%486.784311,68142.1%37.9%
56.82%446.984010,81965.0%50.0%
57.14%427.080612,18473.7%43.5%
40.48%426.974011,86041.2%40.0%
37.50%406.975912,08322.2%50.0%
48.72%396.671712,15157.1%44.0%
55.26%386.877112,30258.8%52.4%
45.71%356.772211,86547.1%44.4%
41.18%346.884111,03546.7%36.8%
53.85%267.073311,84154.5%53.3%
60.00%257.286011,87858.3%61.5%
52.00%256.582311,92346.1%58.3%
60.00%256.882712,30746.1%75.0%
44.00%257.199211,66545.5%42.9%
41.67%247.172011,58241.7%41.7%
66.67%246.57159,04168.8%62.5%
65.22%237.390911,08754.5%75.0%
43.48%237.172911,50936.4%50.0%
31.82%226.880812,38525.0%35.7%
45.45%226.583612,39062.5%35.7%
38.10%216.776211,37545.5%30.0%
52.38%217.386212,24266.7%41.7%
26.32%197.595111,70244.4%10.0%
38.89%186.790512,16820.0%62.5%
50.00%186.971510,37253.9%40.0%
43.75%166.365711,25650.0%37.5%
46.67%157.01,17012,03844.4%50.0%
80.00%157.085211,378100.0%66.7%
57.14%147.490211,55266.7%50.0%
23.08%136.65948,54325.0%20.0%
41.67%127.772611,92433.3%50.0%
50.00%125.966810,52740.0%57.1%
50.00%107.179812,08380.0%20.0%
22.22%96.867710,72933.3%16.7%
66.67%97.197612,87575.0%60.0%
25.00%85.65859,20916.7%50.0%
50.00%86.685812,11966.7%40.0%
57.14%76.11,00913,2380.0%66.7%
85.71%76.888711,43375.0%100.0%
83.33%67.098614,052100.0%75.0%
66.67%61.53498,26775.0%50.0%
66.67%67.475214,37966.7%66.7%
50.00%66.185913,05150.0%50.0%
33.33%67.697111,0610.0%66.7%
66.67%68.17229,11060.0%100.0%
66.67%67.39018,485100.0%0.0%
40.00%56.194311,0970.0%66.7%
60.00%56.998211,51166.7%50.0%
40.00%53.158911,323100.0%0.0%
40.00%55.471212,44550.0%33.3%
0.00%51.93948,6730.0%0.0%
20.00%52.85979,6710.0%33.3%
60.00%57.21,27915,572100.0%50.0%
60.00%56.981111,77166.7%50.0%
40.00%53.34778,34650.0%0.0%
20.00%56.61,0429,98733.3%0.0%
60.00%57.61,14813,7300.0%100.0%

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Orianna vs Karthus - Frequently Asked Questions

How does Orianna do against Karthus in League of Legends?

Orianna wins the Orianna vs Karthus matchup with a 60.0% win rate compared to Karthus's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.5.

How does Orianna do against Karthus in the early game?

In the early game, Orianna has the advantage against Karthus with a 100.0% win rate versus 0.0%. Orianna players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Orianna do against Karthus in the late game?

In the late game, Orianna takes over the Orianna vs Karthus matchup with a 50.0% win rate compared to 50.0%. Orianna scales better into team fights and objective contests after 25 minutes.

Who wins the Orianna vs Karthus matchup?

Orianna wins the matchup against Karthus with a 60.0% win rate in League of Legends patch 26.5. The 20.0 percentage point advantage means Orianna is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Orianna build against Karthus?

The best Orianna build against Karthus includes Luden's Echo, Shadowflame, Banshee's Veil with Crimson Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Orianna runes against Karthus?

The best Orianna runes against Karthus use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Orianna vs Karthus matchup. See the full rune breakdown in the matchup comparison above.

Does Orianna counter Karthus?

Yes, Orianna has a favorable matchup against Karthus with a 60.0% win rate. Orianna strongly counters Karthus in lane based on current patch 26.5 data.

How do I play Orianna against Karthus?

When playing Orianna against Karthus, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.