Syndra - League of Legends Champion
Win Rate
49.6%
Pick Rate
1.7%

Syndravs Senna

CMage
Patch26.10
Matches788,689
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Syndra vs Senna is a decisive matchup in LoL patch 26.10. Syndra wins with a 57.1% win rate (+14.3%) over Senna based on 7 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Senna matchup.

Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Senna - 57.1% win rateSenna(57.1%)
Syndra - 57.1% win rate in this matchup
Syndra
57.1% WR
VS
Senna vs Syndra matchup - 42.9% win rate
Senna
42.9% WR

Who Wins the Syndra vs Senna Matchup?

Syndra wins the Syndra vs Senna matchup
Winner
Syndra
Matches: 7
57.1%
Win Rate
42.9%
3.4
CS / min
3.1
757
DMG / min
646
10,310
Gold / game
11,018
84
Heal / min
465
257
DMG Mitigated / min
336
1.5
CC / min
1.1
50.0%
Early Game WR
50.0%
60.0%
Late Game WR
40.0%

Syndra vs Senna Matchup Summary

The Syndra vs Senna matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Syndra wins with a 57.1% win rate compared to Senna's 42.9%, giving Syndra a 14.3 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Senna players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Senna leads by 460 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra players can confidently pick into Senna and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Senna away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Senna Laning Phase Breakdown

Syndra wins the laning phase against Senna in League of Legends

Syndra is favored during the laning phase against Senna, winning 3 out of 5 key stat categories. Syndra holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
3.4Syndra
3.1Senna
Syndra and Senna farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
757Syndra
646Senna
Syndra heavily out-damages Senna by 110 DMG/min, dominating both short trades and all-in fights. Senna should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
10,310Syndra
11,018Senna
Senna earns 708 more gold per game than Syndra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Senna slightly faster item completions.
Utility
1.5Syndra
1.1Senna
Syndra provides 0.4 seconds more crowd control per minute than Senna, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.
Sustain
341Syndra
801Senna
Senna vastly out-sustains Syndra, healing and mitigating 460 more damage per minute. This massive durability gap means Senna can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Syndra Build Against Senna

Spellslinger's Shoes is the optimal boots choice against Senna, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Senna are Stormsurge, Shadowflame and Rabadon's Deathcap. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Senna. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Senna matchup.

Early Game vs Late Game

Early Game
Syndra
50.0%
+0.0% advantage
Syndra early game win rateSyndra50.0%
Senna early game win rateSenna50.0%
Late Game
Syndra
60.0%
+20.0% advantage
Syndra late game win rateSyndra60.0%
Senna late game win rateSenna40.0%

The early game (first 15 minutes) is a toss-up between Syndra and Senna, with Syndra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Syndra is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Senna. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Senna players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Syndra Runes Against Senna

Inspiration rune tree - Syndra primary runes vs SennaInspiration
First Strike - best Syndra rune vs SennaMagical Footwear - best Syndra rune vs SennaTriple Tonic - best Syndra rune vs SennaJack Of All Trades - best Syndra rune vs Senna
Sorcery rune tree - Syndra secondary runes vs SennaSorcery
Celerity - best Syndra rune vs SennaScorch - best Syndra rune vs Senna
100.0% WR

Running Inspiration primary with Sorcery secondary allows Syndra to press their advantage against Senna, amplifying the strengths that make this a favorable matchup.


Syndra matchup data for League of Legends patch 26.10. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.08%1397.294312,82942.4%57.5%
50.89%1126.884611,98850.0%51.6%
50.94%1067.086612,54755.6%47.5%
53.54%997.289712,98555.0%52.5%
47.78%906.686012,20241.9%50.9%
53.41%886.684612,85047.1%57.4%
39.53%866.996613,53544.0%37.7%
44.30%796.586511,29837.8%50.0%
39.24%796.674910,97342.5%35.9%
54.55%776.687711,53848.6%59.5%
59.70%676.998712,06074.2%47.2%
51.56%646.980411,85866.7%40.5%
36.07%616.982512,09329.0%43.3%
49.15%596.493112,17425.9%68.8%
40.35%576.790212,03243.5%38.2%
50.00%546.679611,97442.9%54.5%
48.98%496.590212,50957.1%42.9%
52.08%487.179811,91954.2%50.0%
59.57%476.893312,20752.4%65.4%
51.11%457.093313,07944.4%55.6%
48.89%456.885212,46847.4%50.0%
48.89%456.71,00313,92461.1%40.7%
61.36%447.294212,84382.3%48.1%
55.81%437.597012,83461.9%50.0%
59.52%426.890111,28461.9%57.1%
51.22%416.879410,39452.6%50.0%
55.00%407.091311,35957.9%52.4%
55.26%386.795012,94546.1%60.0%
41.67%366.495911,44838.9%44.4%
44.44%366.680912,70230.8%52.2%
61.11%367.188812,43252.9%68.4%
68.57%356.897212,73950.0%81.0%
56.25%327.11,01113,67277.8%47.8%
78.13%327.11,03913,88578.6%77.8%
37.04%277.193713,25645.5%31.3%
55.56%276.482211,62646.1%64.3%
46.15%266.61,11513,17650.0%44.4%
54.17%247.086213,12577.8%40.0%
45.83%247.485413,20260.0%35.7%
62.50%247.41,07313,53454.5%69.2%
42.86%216.81,02411,85255.6%33.3%
30.00%206.789714,1500.0%35.3%
42.11%197.196912,73950.0%36.4%
31.58%196.394411,74020.0%35.7%
38.89%186.899413,29120.0%62.5%
55.56%187.094113,07275.0%50.0%
55.56%186.996514,37857.1%54.5%
20.00%155.886410,66228.6%12.5%
40.00%157.378610,71533.3%50.0%
42.86%147.198613,38340.0%44.4%
53.85%136.992512,32160.0%50.0%
30.77%136.385211,98216.7%42.9%
46.15%136.189614,86566.7%40.0%
61.54%137.31,04414,76950.0%66.7%
50.00%127.192310,52942.9%60.0%
41.67%126.81,00214,69375.0%25.0%
63.64%117.01,06215,4680.0%70.0%
63.64%116.394113,04575.0%57.1%
36.36%117.183613,81340.0%33.3%
44.44%96.294212,27050.0%40.0%
66.67%97.61,01913,85725.0%100.0%
75.00%86.787412,996100.0%60.0%
50.00%87.11,02513,07625.0%75.0%
37.50%87.394412,91133.3%40.0%
57.14%76.293114,01133.3%75.0%
57.14%73.475710,31050.0%60.0%
16.67%66.581810,1530.0%25.0%
50.00%67.11,02712,42333.3%66.7%
83.33%66.61,04811,61366.7%100.0%
83.33%65.71,27413,20775.0%100.0%
33.33%67.61,32314,1310.0%40.0%
60.00%53.71,02613,873100.0%50.0%
80.00%57.11,12012,76866.7%100.0%
60.00%53.01,00310,514100.0%33.3%
60.00%57.51,00919,2770.0%60.0%
60.00%57.486315,2150.0%75.0%
60.00%56.91,10915,7780.0%75.0%
40.00%57.379412,87950.0%33.3%
60.00%57.71,02516,41166.7%50.0%
60.00%56.397112,25866.7%50.0%
40.00%53.36917,86440.0%0.0%
80.00%57.21,19113,547100.0%66.7%

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Syndra vs Senna - Frequently Asked Questions

How does Syndra do against Senna in League of Legends?

Syndra wins the Syndra vs Senna matchup with a 57.1% win rate compared to Senna's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.10.

How does Syndra do against Senna in the early game?

In the early game, Syndra has the advantage against Senna with a 50.0% win rate versus 50.0%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Senna in the late game?

In the late game, Syndra takes over the Syndra vs Senna matchup with a 60.0% win rate compared to 40.0%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Senna matchup?

Syndra wins the matchup against Senna with a 57.1% win rate in League of Legends patch 26.10. The 14.3 percentage point advantage means Syndra is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Syndra build against Senna?

The best Syndra build against Senna includes Stormsurge, Shadowflame, Rabadon's Deathcap with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Senna?

The best Syndra runes against Senna use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Senna matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Senna?

Yes, Syndra has a favorable matchup against Senna with a 57.1% win rate. Syndra strongly counters Senna in lane based on current patch 26.10 data.

How do I play Syndra against Senna?

When playing Syndra against Senna, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.