Syndravs Vayne
Syndra vs Vayne is a decisive matchup in LoL patch 26.10. Vayne wins with a 55.6% win rate (+11.1%) over Syndra based on 9 games. Vayne wins the early laning phase while Syndra scales better into the late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Vayne matchup.
Syndra Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Syndra vs Vayne Matchup?
Syndra vs Vayne Matchup Summary
The Syndra vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Vayne wins with a 55.6% win rate compared to Syndra's 44.4%, giving Vayne a 11.1 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Syndra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Syndra reaches their power spikes, while Syndra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Syndra leads by 0.8s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne has a strong advantage in this matchup. Syndra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vayne overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Syndra vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Syndra, winning 3 out of 5 key stat categories. Vayne holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.
Best Syndra Build Against Vayne
Spellslinger's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Vayne are Luden's Echo, Stormsurge and Shadowflame. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Vayne matchup.
Early Game vs Late Game
Syndra0.0%
Vayne100.0%Syndra57.1%Vayne42.9%Vayne dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Syndra. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Syndra is far superior in the late game (25+ minutes), boasting a 57.1% win rate — 14.3 points above Vayne. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Syndra reaches their scaling breakpoints. If Syndra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Syndra Runes Against Vayne
Sorcery
Precision
The Sorcery and Precision rune setup gives Syndra the best tools to compete against Vayne in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Syndra matchup data for League of Legends patch 26.10. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 52.68% | 205 | 6.9 | 894 | 12,286 | 53.2% | 52.3% | |
| 52.91% | 172 | 7.0 | 860 | 12,783 | 48.6% | 56.0% | |
| 46.83% | 126 | 6.7 | 855 | 12,566 | 50.0% | 44.9% | |
| 49.21% | 126 | 6.8 | 998 | 13,078 | 46.9% | 50.6% | |
| 47.15% | 123 | 6.6 | 896 | 13,008 | 53.2% | 43.4% | |
| 50.00% | 116 | 6.4 | 819 | 11,894 | 48.0% | 51.5% | |
| 49.12% | 114 | 7.1 | 955 | 12,414 | 44.6% | 53.5% | |
| 49.09% | 110 | 6.7 | 895 | 12,503 | 42.2% | 53.9% | |
| 40.78% | 103 | 6.5 | 868 | 12,342 | 37.2% | 43.3% | |
| 54.00% | 100 | 6.4 | 893 | 12,635 | 53.1% | 54.4% | |
| 45.45% | 88 | 6.4 | 832 | 11,572 | 51.2% | 40.4% | |
| 51.25% | 80 | 6.7 | 930 | 12,203 | 68.4% | 35.7% | |
| 50.00% | 80 | 7.0 | 818 | 12,151 | 48.5% | 51.1% | |
| 48.72% | 78 | 6.5 | 880 | 12,284 | 53.1% | 45.6% | |
| 46.05% | 76 | 6.9 | 940 | 12,387 | 45.2% | 46.7% | |
| 62.16% | 74 | 7.0 | 886 | 12,613 | 61.8% | 62.5% | |
| 46.48% | 71 | 6.5 | 876 | 11,652 | 47.5% | 45.2% | |
| 57.75% | 71 | 6.6 | 807 | 11,798 | 60.0% | 56.1% | |
| 48.48% | 66 | 6.5 | 787 | 11,514 | 39.4% | 57.6% | |
| 51.61% | 62 | 6.8 | 937 | 13,217 | 53.6% | 50.0% | |
| 60.34% | 58 | 6.9 | 900 | 12,192 | 70.8% | 52.9% | |
| 50.00% | 52 | 6.9 | 917 | 12,414 | 50.0% | 50.0% | |
| 53.85% | 52 | 7.1 | 1,025 | 12,724 | 52.2% | 55.2% | |
| 47.06% | 51 | 7.3 | 985 | 12,977 | 45.0% | 48.4% | |
| 45.10% | 51 | 6.5 | 999 | 12,518 | 54.5% | 37.9% | |
| 53.06% | 49 | 6.9 | 800 | 11,603 | 59.1% | 48.1% | |
| 66.67% | 48 | 6.5 | 938 | 13,058 | 55.6% | 73.3% | |
| 46.81% | 47 | 7.0 | 1,055 | 13,171 | 43.8% | 48.4% | |
| 57.45% | 47 | 6.7 | 996 | 12,588 | 62.5% | 54.8% | |
| 55.32% | 47 | 6.8 | 928 | 13,670 | 60.0% | 51.9% | |
| 48.78% | 41 | 6.7 | 1,081 | 14,110 | 53.9% | 46.4% | |
| 37.50% | 40 | 7.0 | 815 | 11,758 | 35.3% | 39.1% | |
| 28.95% | 38 | 6.9 | 842 | 12,272 | 33.3% | 26.1% | |
| 45.95% | 37 | 6.6 | 922 | 12,258 | 50.0% | 43.5% | |
| 42.86% | 35 | 6.9 | 951 | 12,036 | 41.2% | 44.4% | |
| 42.42% | 33 | 7.1 | 926 | 13,343 | 50.0% | 36.8% | |
| 57.58% | 33 | 6.5 | 906 | 12,250 | 60.0% | 55.6% | |
| 58.06% | 31 | 6.6 | 976 | 12,460 | 58.3% | 57.9% | |
| 55.56% | 27 | 6.8 | 928 | 13,016 | 66.7% | 46.7% | |
| 37.04% | 27 | 7.4 | 923 | 11,326 | 33.3% | 41.7% | |
| 46.15% | 26 | 6.8 | 933 | 12,654 | 58.3% | 35.7% | |
| 40.00% | 25 | 6.8 | 894 | 11,490 | 30.0% | 46.7% | |
| 56.00% | 25 | 6.8 | 914 | 13,517 | 55.6% | 56.3% | |
| 56.00% | 25 | 7.1 | 1,080 | 14,150 | 44.4% | 62.5% | |
| 50.00% | 24 | 6.9 | 998 | 13,011 | 25.0% | 62.5% | |
| 45.83% | 24 | 5.2 | 939 | 12,671 | 60.0% | 42.1% | |
| 43.48% | 23 | 6.8 | 1,077 | 14,566 | 57.1% | 37.5% | |
| 60.87% | 23 | 7.3 | 862 | 12,999 | 50.0% | 69.2% | |
| 60.00% | 20 | 7.1 | 953 | 14,411 | 66.7% | 57.1% | |
| 45.00% | 20 | 7.1 | 956 | 12,224 | 20.0% | 70.0% | |
| 50.00% | 18 | 6.7 | 1,006 | 14,384 | 71.4% | 36.4% | |
| 27.78% | 18 | 6.6 | 831 | 13,495 | 16.7% | 33.3% | |
| 72.22% | 18 | 7.5 | 925 | 13,089 | 80.0% | 62.5% | |
| 55.56% | 18 | 7.1 | 957 | 13,351 | 55.6% | 55.6% | |
| 76.47% | 17 | 6.4 | 1,046 | 12,526 | 75.0% | 77.8% | |
| 81.25% | 16 | 6.8 | 877 | 12,832 | 100.0% | 72.7% | |
| 56.25% | 16 | 7.0 | 1,063 | 12,194 | 50.0% | 62.5% | |
| 53.85% | 13 | 7.4 | 838 | 12,716 | 66.7% | 42.9% | |
| 46.15% | 13 | 6.4 | 1,078 | 13,651 | 100.0% | 30.0% | |
| 53.85% | 13 | 6.6 | 877 | 11,981 | 44.4% | 75.0% | |
| 38.46% | 13 | 6.6 | 1,028 | 13,826 | 25.0% | 44.4% | |
| 50.00% | 12 | 4.3 | 880 | 10,336 | 33.3% | 55.6% | |
| 72.73% | 11 | 7.1 | 1,006 | 11,584 | 66.7% | 80.0% | |
| 27.27% | 11 | 5.2 | 878 | 12,226 | 33.3% | 25.0% | |
| 63.64% | 11 | 7.0 | 1,272 | 14,607 | 50.0% | 66.7% | |
| 54.55% | 11 | 7.3 | 1,311 | 13,336 | 50.0% | 57.1% | |
| 40.00% | 10 | 6.2 | 831 | 12,118 | 33.3% | 50.0% | |
| 60.00% | 10 | 6.5 | 895 | 13,469 | 50.0% | 66.7% | |
| 33.33% | 9 | 6.8 | 803 | 11,854 | 20.0% | 50.0% | |
| 44.44% | 9 | 6.5 | 688 | 10,601 | 0.0% | 57.1% | |
| 44.44% | 9 | 6.9 | 1,173 | 15,861 | 50.0% | 33.3% | |
| 22.22% | 9 | 7.2 | 938 | 12,211 | 20.0% | 25.0% | |
| 55.56% | 9 | 7.3 | 1,096 | 11,222 | 40.0% | 75.0% | |
| 62.50% | 8 | 8.0 | 898 | 11,926 | 50.0% | 75.0% | |
| 50.00% | 8 | 7.4 | 984 | 15,209 | 66.7% | 40.0% | |
| 14.29% | 7 | 7.2 | 719 | 8,957 | 0.0% | 50.0% | |
| 28.57% | 7 | 3.9 | 1,005 | 9,232 | 20.0% | 50.0% | |
| 42.86% | 7 | 7.1 | 878 | 11,099 | 66.7% | 25.0% | |
| 28.57% | 7 | 6.0 | 904 | 11,418 | 33.3% | 25.0% | |
| 42.86% | 7 | 6.9 | 929 | 13,057 | 66.7% | 25.0% | |
| 28.57% | 7 | 6.6 | 871 | 14,053 | 0.0% | 33.3% | |
| 71.43% | 7 | 6.7 | 1,092 | 14,315 | 33.3% | 100.0% | |
| 66.67% | 6 | 7.3 | 796 | 13,167 | 50.0% | 75.0% | |
| 66.67% | 6 | 7.7 | 860 | 12,460 | 75.0% | 50.0% | |
| 66.67% | 6 | 7.6 | 1,008 | 13,590 | 66.7% | 66.7% | |
| 66.67% | 6 | 8.2 | 1,192 | 11,452 | 75.0% | 50.0% | |
| 16.67% | 6 | 5.2 | 713 | 9,725 | 25.0% | 0.0% | |
| 66.67% | 6 | 7.3 | 1,162 | 9,931 | 50.0% | 100.0% | |
| 60.00% | 5 | 5.6 | 591 | 6,991 | 75.0% | 0.0% | |
| 60.00% | 5 | 1.6 | 610 | 7,280 | 66.7% | 50.0% | |
| 100.00% | 5 | 7.4 | 947 | 11,589 | 100.0% | 100.0% | |
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Syndra vs Vayne - Frequently Asked Questions
How does Syndra do against Vayne in League of Legends?
Vayne wins the Syndra vs Vayne matchup with a 55.6% win rate compared to Syndra's 44.4%, a 11.1 percentage point difference. This data is based on 9 recent ranked games in patch 26.10.
How does Syndra do against Vayne in the early game?
In the early game, Vayne has the advantage against Syndra with a 100.0% win rate versus 0.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Syndra do against Vayne in the late game?
In the late game, Syndra takes over the Syndra vs Vayne matchup with a 57.1% win rate compared to 42.9%. Syndra scales better into team fights and objective contests after 25 minutes.
Who wins the Syndra vs Vayne matchup?
Vayne wins the matchup against Syndra with a 55.6% win rate in League of Legends patch 26.10. The 11.1 percentage point advantage means Vayne is significantly favored in this lane matchup based on 9 games analyzed.
What is the best Syndra build against Vayne?
The best Syndra build against Vayne includes Luden's Echo, Stormsurge, Shadowflame with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Syndra runes against Vayne?
The best Syndra runes against Vayne use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Syndra counter Vayne?
No, Syndra struggles against Vayne with only a 44.4% win rate. Vayne has the advantage in this matchup. Syndra players should focus on safe farming and avoiding extended trades to minimize Vayne's lead.
How do I play Syndra against Vayne?
When playing Syndra against Vayne, play cautiously and avoid Vayne's power spikes. Focus on safe farming — you outscale Vayne in the late game. Use the matchup-specific build and runes above to optimize your chances.