Win Rate
49.2%
Pick Rate
4.0%
Syndravs Vayne
Patch26.17
Matches368,800
LaneAll Lanes
TierAll Tiers
Last UpdatedAug 29, 2026 UTC
MethodologyData Methodology
AuthorDakota Chinnick
Syndra vs Vayne is a very close matchup in LoL patch 26.17. Syndra wins with a 50.0% win rate (+0.0%) over Vayne based on 18 games. Vayne wins the early laning phase while Syndra scales better into the late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Vayne matchup.
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Syndra Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Compare against an opponent
Syndra
50.0% WR
VS
Vayne
50.0% WR
Who Wins the Syndra vs Vayne Matchup?
Winner
Syndra
Matches: 18
50.0%
50.0%
6.9
6.5
909
928
13,945
14,546
63
273
304
493
1.4
0.4
42.9%
57.1%
54.5%
45.5%
Syndra vs Vayne Matchup Summary
The Syndra vs Vayne matchup is essentially a coin-flip matchup in League of Legends ranked play. Based on 18 recent matches analyzed, Syndra wins with a 50.0% win rate compared to Vayne's 50.0%, giving Syndra a 0.0 percentage point advantage. Game phase dynamics play a critical role here: Vayne controls the early laning stage, but Syndra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Vayne needs to press advantages before Syndra reaches their power spikes, while Syndra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Syndra leads by 1.0s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra has a statistical edge, but the margin is close enough that respecting Vayne's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Syndra vs Vayne Laning Phase Breakdown
Vayne is favored during the laning phase against Syndra, winning 3 out of 5 key stat categories. Vayne holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.
Farming
6.9Syndra
6.5Vayne
Syndra edges out Vayne by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.Damage
909Syndra
928Vayne
Damage output is virtually even between Syndra and Vayne, with only 20 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.Economy
13,945Syndra
14,546Vayne
Vayne earns 601 more gold per game than Syndra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.Utility
1.4Syndra
0.4Vayne
Syndra brings significantly more crowd control than Vayne, with 1.0 more seconds of CC per minute. This large utility gap makes Syndra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.Sustain
366Syndra
767Vayne
Vayne vastly out-sustains Syndra, healing and mitigating 400 more damage per minute. This massive durability gap means Vayne can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.Best Syndra Build Against Vayne
Spellslinger's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Vayne are Hextech Rocketbelt, Rabadon's Deathcap and Blackfire Torch. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Vayne matchup.
Early Game vs Late Game
⚔
Early Game
Vayne
57.1%
+14.3% advantage
Syndra42.9%
Vayne57.1%♕
Late Game
Syndra
54.5%
+9.1% advantage
Syndra54.5%Vayne45.5%Vayne dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Syndra. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Syndra is far superior in the late game (25+ minutes), boasting a 54.5% win rate — 9.1 points above Vayne. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Vayne must aggressively press their early advantage and close out the game before Syndra reaches their scaling breakpoints. If Syndra survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Syndra Runes Against Vayne
Sorcery
Inspiration
50.0% WR
The Sorcery primary with Inspiration secondary combination helps Syndra maximize their potential in this closely contested matchup, providing the right mix of offensive and defensive tools to edge out Vayne.
Syndra matchup data for League of Legends patch 26.17. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 43.22% | 118 | 6.8 | 825 | 12,109 | 49.0% | 39.1% | |
| 47.41% | 116 | 7.3 | 916 | 12,916 | 48.1% | 46.8% | |
| 53.33% | 105 | 7.0 | 865 | 12,245 | 49.0% | 57.1% | |
| 54.46% | 101 | 7.0 | 970 | 12,965 | 54.0% | 54.7% | |
| 50.00% | 88 | 7.0 | 1,013 | 13,199 | 60.0% | 43.4% | |
| 45.45% | 88 | 7.3 | 918 | 13,546 | 34.5% | 50.9% | |
| 46.67% | 75 | 6.5 | 914 | 12,351 | 44.4% | 47.9% | |
| 45.21% | 73 | 6.5 | 866 | 12,770 | 38.7% | 50.0% | |
| 45.83% | 72 | 6.7 | 864 | 11,446 | 39.4% | 51.3% | |
| 42.25% | 71 | 6.7 | 875 | 11,300 | 41.2% | 43.2% | |
| 47.14% | 70 | 6.6 | 878 | 12,049 | 51.7% | 43.9% | |
| 50.77% | 65 | 6.7 | 923 | 12,733 | 44.4% | 55.3% | |
| 53.85% | 65 | 6.9 | 883 | 12,903 | 48.3% | 58.3% | |
| 46.88% | 64 | 6.7 | 852 | 11,781 | 50.0% | 44.4% | |
| 45.31% | 64 | 7.0 | 843 | 13,831 | 40.9% | 47.6% | |
| 52.38% | 63 | 6.8 | 926 | 12,477 | 43.8% | 61.3% | |
| 50.91% | 55 | 7.0 | 911 | 13,189 | 47.6% | 52.9% | |
| 41.18% | 51 | 6.7 | 792 | 13,838 | 47.1% | 38.2% | |
| 50.00% | 50 | 6.8 | 857 | 12,430 | 45.8% | 53.9% | |
| 48.00% | 50 | 7.0 | 856 | 12,489 | 44.4% | 50.0% | |
| 65.96% | 47 | 7.0 | 849 | 13,528 | 53.9% | 70.6% | |
| 41.30% | 46 | 6.9 | 983 | 13,661 | 57.1% | 34.4% | |
| 52.38% | 42 | 6.9 | 954 | 12,894 | 70.6% | 40.0% | |
| 62.50% | 40 | 6.7 | 956 | 13,464 | 57.9% | 66.7% | |
| 64.10% | 39 | 6.6 | 813 | 11,852 | 64.7% | 63.6% | |
| 52.63% | 38 | 7.0 | 843 | 12,214 | 42.9% | 64.7% | |
| 63.89% | 36 | 6.9 | 811 | 10,881 | 68.2% | 57.1% | |
| 33.33% | 36 | 7.5 | 907 | 11,334 | 33.3% | 33.3% | |
| 48.57% | 35 | 7.1 | 795 | 12,597 | 47.4% | 50.0% | |
| 47.06% | 34 | 7.1 | 927 | 12,019 | 55.6% | 37.5% | |
| 55.88% | 34 | 6.8 | 985 | 13,228 | 68.8% | 44.4% | |
| 45.45% | 33 | 6.4 | 879 | 13,406 | 61.5% | 35.0% | |
| 50.00% | 32 | 7.0 | 1,044 | 12,714 | 46.1% | 52.6% | |
| 62.50% | 32 | 6.8 | 843 | 13,157 | 57.1% | 66.7% | |
| 46.67% | 30 | 6.8 | 945 | 11,263 | 50.0% | 40.0% | |
| 50.00% | 30 | 6.8 | 1,015 | 12,716 | 45.5% | 52.6% | |
| 65.52% | 29 | 6.9 | 1,068 | 13,450 | 69.2% | 62.5% | |
| 48.15% | 27 | 6.6 | 854 | 10,992 | 38.5% | 57.1% | |
| 55.56% | 27 | 6.9 | 919 | 12,137 | 54.5% | 56.3% | |
| 48.00% | 25 | 7.8 | 924 | 13,133 | 50.0% | 42.9% | |
| 32.00% | 25 | 6.6 | 841 | 10,981 | 14.3% | 54.5% | |
| 34.78% | 23 | 6.6 | 921 | 13,638 | 33.3% | 35.3% | |
| 36.36% | 22 | 7.3 | 687 | 11,112 | 50.0% | 28.6% | |
| 50.00% | 22 | 6.8 | 811 | 11,690 | 57.1% | 46.7% | |
| 54.55% | 22 | 6.0 | 928 | 13,084 | 50.0% | 57.1% | |
| 47.62% | 21 | 6.6 | 1,232 | 12,823 | 60.0% | 36.4% | |
| 40.00% | 20 | 7.0 | 907 | 13,516 | 25.0% | 50.0% | |
| 42.11% | 19 | 7.2 | 902 | 13,957 | 36.4% | 50.0% | |
| 52.63% | 19 | 6.9 | 1,153 | 12,781 | 62.5% | 45.5% | |
| 61.11% | 18 | 7.0 | 915 | 12,835 | 71.4% | 54.5% | |
| 50.00% | 18 | 6.9 | 909 | 13,945 | 42.9% | 54.5% | |
| 58.82% | 17 | 7.5 | 1,043 | 13,335 | 62.5% | 55.6% | |
| 64.71% | 17 | 5.6 | 887 | 12,376 | 71.4% | 60.0% | |
| 12.50% | 16 | 6.3 | 867 | 13,284 | 20.0% | 9.1% | |
| 53.33% | 15 | 7.0 | 921 | 13,371 | 25.0% | 63.6% | |
| 46.67% | 15 | 7.2 | 766 | 12,008 | 66.7% | 16.7% | |
| 46.67% | 15 | 6.9 | 768 | 9,953 | 50.0% | 42.9% | |
| 57.14% | 14 | 5.5 | 1,018 | 13,267 | 33.3% | 75.0% | |
| 42.86% | 14 | 7.3 | 822 | 13,999 | 40.0% | 44.4% | |
| 42.86% | 14 | 6.4 | 810 | 11,789 | 57.1% | 28.6% | |
| 38.46% | 13 | 6.7 | 936 | 15,885 | 0.0% | 50.0% | |
| 61.54% | 13 | 7.1 | 985 | 11,903 | 42.9% | 83.3% | |
| 76.92% | 13 | 7.0 | 1,009 | 14,214 | 50.0% | 88.9% | |
| 46.15% | 13 | 6.8 | 800 | 13,111 | 40.0% | 50.0% | |
| 46.15% | 13 | 7.2 | 1,116 | 13,618 | 33.3% | 50.0% | |
| 25.00% | 12 | 6.9 | 923 | 14,150 | 50.0% | 20.0% | |
| 66.67% | 12 | 7.7 | 1,059 | 12,260 | 85.7% | 40.0% | |
| 72.73% | 11 | 7.2 | 988 | 14,171 | 75.0% | 71.4% | |
| 60.00% | 10 | 6.5 | 745 | 12,894 | 33.3% | 71.4% | |
| 50.00% | 10 | 7.4 | 752 | 11,472 | 66.7% | 25.0% | |
| 50.00% | 10 | 4.9 | 894 | 11,966 | 25.0% | 66.7% | |
| 60.00% | 10 | 6.5 | 937 | 11,852 | 57.1% | 66.7% | |
| 55.56% | 9 | 7.0 | 751 | 12,987 | 33.3% | 66.7% | |
| 66.67% | 9 | 6.6 | 881 | 13,102 | 66.7% | 66.7% | |
| 62.50% | 8 | 4.5 | 801 | 11,403 | 50.0% | 75.0% | |
| 25.00% | 8 | 6.8 | 661 | 10,842 | 33.3% | 20.0% | |
| 42.86% | 7 | 6.6 | 931 | 11,413 | 50.0% | 33.3% | |
| 57.14% | 7 | 6.2 | 969 | 14,318 | 100.0% | 40.0% | |
| 28.57% | 7 | 7.2 | 1,084 | 14,686 | 50.0% | 20.0% | |
| 57.14% | 7 | 7.9 | 1,149 | 12,044 | 75.0% | 33.3% | |
| 66.67% | 6 | 3.9 | 862 | 12,133 | 50.0% | 75.0% | |
| 33.33% | 6 | 6.9 | 1,031 | 13,238 | 66.7% | 0.0% | |
| 33.33% | 6 | 7.0 | 1,143 | 15,118 | 50.0% | 25.0% | |
| 40.00% | 5 | 7.3 | 674 | 6,815 | 66.7% | 0.0% | |
| 40.00% | 5 | 6.5 | 835 | 9,738 | 50.0% | 0.0% | |
| 20.00% | 5 | 5.7 | 1,048 | 10,796 | 33.3% | 0.0% | |
| 40.00% | 5 | 7.0 | 1,167 | 16,305 | 0.0% | 66.7% | |
| 100.00% | 5 | 7.6 | 1,053 | 12,823 | 100.0% | 100.0% | |
| 40.00% | 5 | 7.6 | 912 | 13,236 | 50.0% | 33.3% | |
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Syndra vs Vayne - Frequently Asked Questions
How does Syndra do against Vayne in League of Legends?
Syndra wins the Syndra vs Vayne matchup with a 50.0% win rate compared to Vayne's 50.0%, a 0.0 percentage point difference. This data is based on 18 recent ranked games in patch 26.17.
How does Syndra do against Vayne in the early game?
In the early game, Vayne has the advantage against Syndra with a 57.1% win rate versus 42.9%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Syndra do against Vayne in the late game?
In the late game, Syndra takes over the Syndra vs Vayne matchup with a 54.5% win rate compared to 45.5%. Syndra scales better into team fights and objective contests after 25 minutes.
Who wins the Syndra vs Vayne matchup?
Syndra wins the matchup against Vayne with a 50.0% win rate in League of Legends patch 26.17. The 0.0 percentage point advantage means Syndra is slightly favored in this lane matchup based on 18 games analyzed.
What is the best Syndra build against Vayne?
The best Syndra build against Vayne includes Hextech Rocketbelt, Rabadon's Deathcap, Blackfire Torch with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Syndra runes against Vayne?
The best Syndra runes against Vayne use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 50.0% win rate in the Syndra vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Syndra counter Vayne?
Yes, Syndra has a favorable matchup against Vayne with a 50.0% win rate. Syndra slightly edges out Vayne in lane based on current patch 26.17 data.
How do I play Syndra against Vayne?
When playing Syndra against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Vayne. Build the recommended items and runes for this specific matchup for the best results.
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