Syndra - League of Legends Champion
Win Rate
52.3%
Pick Rate
2.9%

Syndravs Seraphine

SMage
Patch26.3
Matches785,220
LaneAll Lanes
TierAll Tiers
Last UpdatedFeb 27, 2026
MethodologyData Methodology

Syndra vs Seraphine is a decisive matchup in LoL patch 26.3. Syndra wins with a 64.3% win rate (+28.6%) over Seraphine based on 14 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Seraphine matchup.

Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 64.3% win rateSeraphine(64.3%)
Syndra - 64.3% win rate in this matchup
Syndra
64.3% WR
VS
Seraphine vs Syndra matchup - 35.7% win rate
Seraphine
35.7% WR

Who Wins the Syndra vs Seraphine Matchup?

Syndra wins the Syndra vs Seraphine matchup
Winner
Syndra
Matches: 14
64.3%
Win Rate
35.7%
6.9
CS / min
5.1
977
DMG / min
534
14,816
Gold / game
10,635
61
Heal / min
274
313
DMG Mitigated / min
379
1.5
CC / min
1.2
66.7%
Early Game WR
33.3%
63.6%
Late Game WR
36.4%

Syndra vs Seraphine Matchup Summary

The Syndra vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 14 recent matches analyzed, Syndra wins with a 64.3% win rate compared to Seraphine's 35.7%, giving Syndra a 28.6 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Seraphine players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Syndra leads by 443 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra players can confidently pick into Seraphine and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Seraphine away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Seraphine Laning Phase Breakdown

Syndra wins the laning phase against Seraphine in League of Legends

Syndra is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.9Syndra
5.1Seraphine
Syndra significantly out-farms Seraphine by 1.8 CS per minute, accumulating an estimated 27 CS lead by mid game. This substantial farming gap gives Syndra a major gold advantage and earlier item completions. Seraphine players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
977Syndra
534Seraphine
Syndra heavily out-damages Seraphine by 443 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
14,816Syndra
10,635Seraphine
Syndra generates a commanding 4,181 more gold per game than Seraphine. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.5Syndra
1.2Seraphine
Syndra provides 0.3 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.
Sustain
374Syndra
653Seraphine
Seraphine vastly out-sustains Syndra, healing and mitigating 279 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Syndra Build Against Seraphine

Spellslinger's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Seraphine are Luden's Echo, Shadowflame and Void Staff. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Seraphine matchup.

Early Game vs Late Game

Early Game
Syndra
66.7%
+33.3% advantage
Syndra early game win rateSyndra66.7%
Seraphine early game win rateSeraphine33.3%
Late Game
Syndra
63.6%
+27.3% advantage
Syndra late game win rateSyndra63.6%
Seraphine late game win rateSeraphine36.4%

Syndra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Seraphine. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Syndra is far superior in the late game (25+ minutes), boasting a 63.6% win rate — 27.3 points above Seraphine. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Seraphine players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Syndra Runes Against Seraphine

Inspiration rune tree - Syndra primary runes vs SeraphineInspiration
First Strike - best Syndra rune vs SeraphineCash Back - best Syndra rune vs SeraphineTriple Tonic - best Syndra rune vs SeraphineJack Of All Trades - best Syndra rune vs Seraphine
Precision rune tree - Syndra secondary runes vs SeraphinePrecision
Presence of Mind - best Syndra rune vs SeraphineCut Down - best Syndra rune vs Seraphine
100.0% WR

Running Inspiration primary with Precision secondary allows Syndra to press their advantage against Seraphine, amplifying the strengths that make this a favorable matchup.


Syndra matchup data for League of Legends patch 26.3. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.3
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.59%2537.195613,30848.3%52.5%
53.97%1897.084513,00852.6%55.0%
51.85%1897.298013,43458.4%47.3%
44.74%1527.185612,91043.8%45.5%
55.15%1367.190813,12248.3%60.3%
44.92%1186.781112,88443.5%45.8%
51.72%1166.682312,09143.1%58.5%
52.17%1156.779912,12637.5%66.1%
46.02%1136.680112,10442.9%48.4%
50.89%1127.297913,06851.0%50.8%
41.67%1086.789812,97332.5%47.1%
65.05%1037.499512,79760.8%69.2%
44.55%1016.882212,08943.1%46.0%
44.68%947.294613,39952.4%38.5%
45.65%926.882412,24947.7%43.8%
48.24%857.185612,67647.5%48.9%
49.41%856.986712,96248.6%50.0%
53.57%847.393212,77156.8%50.0%
57.83%837.092413,25654.3%60.4%
54.32%816.689912,81462.9%47.8%
45.00%806.682312,26647.4%42.9%
51.90%797.295611,87050.0%53.9%
67.61%716.790213,28070.4%65.9%
57.75%716.691512,78353.6%60.5%
58.46%657.096413,62565.2%54.8%
43.75%646.988712,20053.3%35.3%
55.74%616.890813,59472.2%48.8%
61.67%606.81,06214,17558.8%62.8%
59.32%596.895212,88066.7%54.3%
61.02%597.190512,71161.5%60.6%
50.00%587.096412,57641.4%58.6%
53.45%587.081510,79458.5%41.2%
50.88%576.984113,10357.9%47.4%
54.55%556.997713,71666.7%48.6%
50.00%467.392712,98450.0%50.0%
61.36%447.41,05914,10768.8%57.1%
47.37%386.596513,35452.9%42.9%
55.56%367.091214,16069.2%47.8%
45.16%317.11,07113,74954.5%40.0%
53.33%307.094313,41954.5%52.6%
57.14%286.994313,70160.0%55.6%
50.00%266.973111,36336.4%60.0%
57.69%267.81,01412,95475.0%42.9%
40.00%256.91,01814,01955.6%31.3%
66.67%246.693312,47866.7%66.7%
50.00%227.31,14913,48838.5%66.7%
61.90%217.189412,74263.6%60.0%
71.43%217.51,17014,15690.9%50.0%
50.00%207.41,16916,02271.4%38.5%
47.37%197.989913,61962.5%36.4%
61.11%186.81,04314,80450.0%66.7%
52.94%176.593814,73666.7%45.5%
47.06%176.798014,12371.4%30.0%
62.50%167.376813,26350.0%75.0%
53.33%157.71,02614,33887.5%14.3%
64.29%146.997714,81666.7%63.6%
78.57%146.696812,35466.7%100.0%
76.92%136.981211,84766.7%85.7%
23.08%137.086012,00628.6%16.7%
66.67%126.51,01513,02771.4%60.0%
58.33%127.270711,91080.0%42.9%
41.67%126.293012,42316.7%66.7%
45.45%115.873511,24180.0%16.7%
54.55%116.61,1349,85457.1%50.0%
54.55%116.391015,4830.0%60.0%
27.27%117.497513,2380.0%37.5%
63.64%117.883310,63683.3%40.0%
50.00%106.01,00913,51566.7%42.9%
40.00%107.51,13011,92325.0%100.0%
70.00%106.81,25214,17183.3%50.0%
30.00%107.41,07316,7470.0%33.3%
66.67%97.21,14913,82260.0%75.0%
55.56%92.278611,347100.0%42.9%
75.00%86.789813,724100.0%50.0%
50.00%86.51,05713,8510.0%57.1%
50.00%87.898213,46233.3%60.0%
0.00%86.882611,4060.0%0.0%
37.50%85.577813,354100.0%16.7%
50.00%86.91,23714,9900.0%66.7%
12.50%87.588712,66225.0%0.0%
37.50%87.095312,48466.7%20.0%
85.71%77.51,16613,00580.0%100.0%
42.86%76.21,00012,8690.0%50.0%
57.14%76.194211,63850.0%60.0%
71.43%73.66729,16975.0%66.7%
42.86%77.087015,5980.0%50.0%
71.43%76.91,02914,504100.0%50.0%
83.33%67.11,24616,036100.0%80.0%
66.67%67.277512,55066.7%66.7%
33.33%67.386510,28040.0%0.0%
50.00%66.41,19212,00866.7%33.3%
83.33%66.81,09212,32450.0%100.0%
60.00%57.11,05315,496100.0%33.3%
60.00%56.896611,952100.0%50.0%
40.00%57.181914,886100.0%0.0%
60.00%56.894813,75766.7%50.0%
60.00%56.881411,49150.0%66.7%
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Syndra vs Seraphine - Frequently Asked Questions

How does Syndra do against Seraphine in League of Legends?

Syndra wins the Syndra vs Seraphine matchup with a 64.3% win rate compared to Seraphine's 35.7%, a 28.6 percentage point difference. This data is based on 14 recent ranked games in patch 26.3.

How does Syndra do against Seraphine in the early game?

In the early game, Syndra has the advantage against Seraphine with a 66.7% win rate versus 33.3%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Seraphine in the late game?

In the late game, Syndra takes over the Syndra vs Seraphine matchup with a 63.6% win rate compared to 36.4%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Seraphine matchup?

Syndra wins the matchup against Seraphine with a 64.3% win rate in League of Legends patch 26.3. The 28.6 percentage point advantage means Syndra is significantly favored in this lane matchup based on 14 games analyzed.

What is the best Syndra build against Seraphine?

The best Syndra build against Seraphine includes Luden's Echo, Shadowflame, Void Staff with Spellslinger's Shoes. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Seraphine?

The best Syndra runes against Seraphine use the Inspiration primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Seraphine?

Yes, Syndra has a favorable matchup against Seraphine with a 64.3% win rate. Syndra strongly counters Seraphine in lane based on current patch 26.3 data.

How do I play Syndra against Seraphine?

When playing Syndra against Seraphine, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.