Syndra - League of Legends Champion
Win Rate
49.7%
Pick Rate
1.7%

Syndravs Seraphine

CMage
Patch26.10
Matches3,013,751
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 30, 2026
MethodologyData Methodology

Syndra vs Seraphine is a decisive matchup in LoL patch 26.10. Seraphine wins with a 72.7% win rate (+45.5%) over Syndra based on 11 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Seraphine matchup.

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Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 27.3% win rate in this matchup
Syndra
27.3% WR
VS
Seraphine vs Syndra matchup - 72.7% win rate
Seraphine
72.7% WR

Who Wins the Syndra vs Seraphine Matchup?

Seraphine wins the Syndra vs Seraphine matchup
Winner
Seraphine
Matches: 11
27.3%
Win Rate
72.7%
5.2
CS / min
4.4
878
DMG / min
628
12,226
Gold / game
11,663
107
Heal / min
523
322
DMG Mitigated / min
449
1.5
CC / min
1.0
33.3%
Early Game WR
66.7%
25.0%
Late Game WR
75.0%

Syndra vs Seraphine Matchup Summary

The Syndra vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 11 recent matches analyzed, Seraphine wins with a 72.7% win rate compared to Syndra's 27.3%, giving Seraphine a 45.5 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Syndra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Seraphine leads by 543 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a strong advantage in this matchup. Syndra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Seraphine overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Seraphine Laning Phase Breakdown

Syndra wins the laning phase against Seraphine in League of Legends

Syndra is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.2Syndra
4.4Seraphine
Syndra significantly out-farms Seraphine by 0.8 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Syndra a major gold advantage and earlier item completions. Seraphine players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
878Syndra
628Seraphine
Syndra heavily out-damages Seraphine by 250 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
12,226Syndra
11,663Seraphine
Syndra earns 563 more gold per game than Seraphine, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Syndra slightly faster item completions.
Utility
1.5Syndra
1.0Seraphine
Syndra provides 0.6 seconds more crowd control per minute than Seraphine, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Syndra coordinate with their jungler and control the pace of skirmishes.
Sustain
429Syndra
971Seraphine
Seraphine vastly out-sustains Syndra, healing and mitigating 543 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Syndra Build Against Seraphine

Sorcerer's Shoes is the optimal boots choice against Seraphine, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Seraphine are Luden's Echo, Stormsurge and Shadowflame. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Seraphine matchup.

Early Game vs Late Game

Early Game
Seraphine
66.7%
+33.3% advantage
Syndra early game win rateSyndra33.3%
Seraphine early game win rateSeraphine66.7%
Late Game
Seraphine
75.0%
+50.0% advantage
Syndra late game win rateSyndra25.0%
Seraphine late game win rateSeraphine75.0%

Seraphine dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Syndra. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Syndra. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Syndra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Syndra Runes Against Seraphine

Sorcery rune tree - Syndra primary runes vs SeraphineSorcery
Arcane Comet - best Syndra rune vs SeraphineAxiom Arcanist - best Syndra rune vs SeraphineTranscendence - best Syndra rune vs SeraphineGathering Storm - best Syndra rune vs Seraphine
Precision rune tree - Syndra secondary runes vs SeraphinePrecision
Legend: Haste - best Syndra rune vs SeraphineCut Down - best Syndra rune vs Seraphine
100.0% WR

The Sorcery and Precision rune setup gives Syndra the best tools to compete against Seraphine in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Syndra matchup data for League of Legends patch 26.10. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.68%2056.989412,28653.2%52.3%
52.91%1727.086012,78348.6%56.0%
46.83%1266.785512,56650.0%44.9%
49.21%1266.899813,07846.9%50.6%
47.15%1236.689613,00853.2%43.4%
50.00%1166.481911,89448.0%51.5%
49.12%1147.195512,41444.6%53.5%
49.09%1106.789512,50342.2%53.9%
40.78%1036.586812,34237.2%43.3%
54.00%1006.489312,63553.1%54.4%
45.45%886.483211,57251.2%40.4%
51.25%806.793012,20368.4%35.7%
50.00%807.081812,15148.5%51.1%
48.72%786.588012,28453.1%45.6%
46.05%766.994012,38745.2%46.7%
62.16%747.088612,61361.8%62.5%
46.48%716.587611,65247.5%45.2%
57.75%716.680711,79860.0%56.1%
48.48%666.578711,51439.4%57.6%
51.61%626.893713,21753.6%50.0%
60.34%586.990012,19270.8%52.9%
50.00%526.991712,41450.0%50.0%
53.85%527.11,02512,72452.2%55.2%
47.06%517.398512,97745.0%48.4%
45.10%516.599912,51854.5%37.9%
53.06%496.980011,60359.1%48.1%
66.67%486.593813,05855.6%73.3%
46.81%477.01,05513,17143.8%48.4%
57.45%476.799612,58862.5%54.8%
55.32%476.892813,67060.0%51.9%
48.78%416.71,08114,11053.9%46.4%
37.50%407.081511,75835.3%39.1%
28.95%386.984212,27233.3%26.1%
45.95%376.692212,25850.0%43.5%
42.86%356.995112,03641.2%44.4%
42.42%337.192613,34350.0%36.8%
57.58%336.590612,25060.0%55.6%
58.06%316.697612,46058.3%57.9%
55.56%276.892813,01666.7%46.7%
37.04%277.492311,32633.3%41.7%
46.15%266.893312,65458.3%35.7%
40.00%256.889411,49030.0%46.7%
56.00%256.891413,51755.6%56.3%
56.00%257.11,08014,15044.4%62.5%
50.00%246.999813,01125.0%62.5%
45.83%245.293912,67160.0%42.1%
43.48%236.81,07714,56657.1%37.5%
60.87%237.386212,99950.0%69.2%
60.00%207.195314,41166.7%57.1%
45.00%207.195612,22420.0%70.0%
50.00%186.71,00614,38471.4%36.4%
27.78%186.683113,49516.7%33.3%
72.22%187.592513,08980.0%62.5%
55.56%187.195713,35155.6%55.6%
76.47%176.41,04612,52675.0%77.8%
81.25%166.887712,832100.0%72.7%
56.25%167.01,06312,19450.0%62.5%
53.85%137.483812,71666.7%42.9%
46.15%136.41,07813,651100.0%30.0%
53.85%136.687711,98144.4%75.0%
38.46%136.61,02813,82625.0%44.4%
50.00%124.388010,33633.3%55.6%
72.73%117.11,00611,58466.7%80.0%
27.27%115.287812,22633.3%25.0%
63.64%117.01,27214,60750.0%66.7%
54.55%117.31,31113,33650.0%57.1%
40.00%106.283112,11833.3%50.0%
60.00%106.589513,46950.0%66.7%
33.33%96.880311,85420.0%50.0%
44.44%96.568810,6010.0%57.1%
44.44%96.91,17315,86150.0%33.3%
22.22%97.293812,21120.0%25.0%
55.56%97.31,09611,22240.0%75.0%
62.50%88.089811,92650.0%75.0%
50.00%87.498415,20966.7%40.0%
14.29%77.27198,9570.0%50.0%
28.57%73.91,0059,23220.0%50.0%
42.86%77.187811,09966.7%25.0%
28.57%76.090411,41833.3%25.0%
42.86%76.992913,05766.7%25.0%
28.57%76.687114,0530.0%33.3%
71.43%76.71,09214,31533.3%100.0%
66.67%67.379613,16750.0%75.0%
66.67%67.786012,46075.0%50.0%
66.67%67.61,00813,59066.7%66.7%
66.67%68.21,19211,45275.0%50.0%
16.67%65.27139,72525.0%0.0%
66.67%67.31,1629,93150.0%100.0%
60.00%55.65916,99175.0%0.0%
60.00%51.66107,28066.7%50.0%
100.00%57.494711,589100.0%100.0%

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Syndra vs Seraphine - Frequently Asked Questions

How does Syndra do against Seraphine in League of Legends?

Seraphine wins the Syndra vs Seraphine matchup with a 72.7% win rate compared to Syndra's 27.3%, a 45.5 percentage point difference. This data is based on 11 recent ranked games in patch 26.10.

How does Syndra do against Seraphine in the early game?

In the early game, Seraphine has the advantage against Syndra with a 66.7% win rate versus 33.3%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Seraphine in the late game?

In the late game, Seraphine takes over the Syndra vs Seraphine matchup with a 75.0% win rate compared to 25.0%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Seraphine matchup?

Seraphine wins the matchup against Syndra with a 72.7% win rate in League of Legends patch 26.10. The 45.5 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 11 games analyzed.

What is the best Syndra build against Seraphine?

The best Syndra build against Seraphine includes Luden's Echo, Stormsurge, Shadowflame with Sorcerer's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Seraphine?

The best Syndra runes against Seraphine use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Seraphine?

No, Syndra struggles against Seraphine with only a 27.3% win rate. Seraphine has the advantage in this matchup. Syndra players should focus on safe farming and avoiding extended trades to minimize Seraphine's lead.

How do I play Syndra against Seraphine?

When playing Syndra against Seraphine, play cautiously and avoid Seraphine's power spikes. Look for jungle assistance and team-dependent plays since Seraphine has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.