Syndra - League of Legends Champion
Win Rate
50.2%
Pick Rate
2.2%

Syndravs Zoe

CMage
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 10, 2026
MethodologyData Methodology

Syndra vs Zoe is a decisive matchup in LoL patch 26.7. Zoe wins with a 62.1% win rate (+24.1%) over Syndra based on 29 games. Zoe holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Zoe matchup.

Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zoe - 37.9% win rateZoe(37.9%)
Syndra - 37.9% win rate in this matchup
Syndra
37.9% WR
VS
Zoe vs Syndra matchup - 62.1% win rate
Zoe
62.1% WR

Who Wins the Syndra vs Zoe Matchup?

Zoe wins the Syndra vs Zoe matchup
Winner
Zoe
Matches: 29
37.9%
Win Rate
62.1%
6.9
CS / min
6.5
802
DMG / min
918
12,048
Gold / game
11,990
65
Heal / min
98
291
DMG Mitigated / min
341
1.2
CC / min
1.2
41.7%
Early Game WR
58.3%
35.3%
Late Game WR
64.7%

Syndra vs Zoe Matchup Summary

The Syndra vs Zoe matchup is a decisive matchup in League of Legends ranked play. Based on 29 recent matches analyzed, Zoe wins with a 62.1% win rate compared to Syndra's 37.9%, giving Zoe a 24.1 percentage point advantage. Zoe dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Syndra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Zoe leads by 83 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Zoe has a strong advantage in this matchup. Syndra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Zoe overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Zoe Laning Phase Breakdown

Zoe wins the laning phase against Syndra in League of Legends

Zoe is favored during the laning phase against Syndra, winning 3 out of 5 key stat categories. Zoe holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.9Syndra
6.5Zoe
Syndra edges out Zoe by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
802Syndra
918Zoe
Zoe heavily out-damages Syndra by 116 DMG/min, dominating both short trades and all-in fights. Syndra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zoe's sustained damage advantage take over.
Economy
12,048Syndra
11,990Zoe
Syndra and Zoe generate nearly equal gold per game, with just a 57 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.2Syndra
1.2Zoe
Both Syndra and Zoe provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
356Syndra
439Zoe
Zoe heals and mitigates 83 more damage per minute than Syndra, providing moderate extra durability. This sustain edge allows Zoe to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Syndra.

Best Syndra Build Against Zoe

Spellslinger's Shoes is the optimal boots choice against Zoe, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Zoe are Luden's Echo, Shadowflame and Rabadon's Deathcap. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build has a 20.0% win rate across 5 games. While the overall matchup may be difficult, this item path gives Syndra the best chance to compete against Zoe. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Zoe matchup.

Early Game vs Late Game

Early Game
Zoe
58.3%
+16.7% advantage
Syndra early game win rateSyndra41.7%
Zoe early game win rateZoe58.3%
Late Game
Zoe
64.7%
+29.4% advantage
Syndra late game win rateSyndra35.3%
Zoe late game win rateZoe64.7%

Zoe dominates the early game (first 15 minutes) with a commanding 58.3% win rate — a 16.7 percentage point lead over Syndra. This lopsided early game means Zoe can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Zoe is far superior in the late game (25+ minutes), boasting a 64.7% win rate — 29.4 points above Syndra. Extended games heavily favor Zoe, whose kit and scaling make them a dominant force in team fights and objective control.

Zoe holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Syndra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Syndra Runes Against Zoe

Inspiration rune tree - Syndra primary runes vs ZoeInspiration
First Strike - best Syndra rune vs ZoeMagical Footwear - best Syndra rune vs ZoeTriple Tonic - best Syndra rune vs ZoeJack Of All Trades - best Syndra rune vs Zoe
Sorcery rune tree - Syndra secondary runes vs ZoeSorcery
Manaflow Band - best Syndra rune vs ZoeTranscendence - best Syndra rune vs Zoe
100.0% WR

The Inspiration and Sorcery rune setup gives Syndra the best tools to compete against Zoe in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Syndra matchup data for League of Legends patch 26.7. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.04%1297.393112,75149.2%60.3%
46.07%897.091912,96650.0%43.6%
50.00%846.885111,63640.0%59.1%
51.85%817.290913,13051.3%52.4%
52.56%787.384812,64655.6%50.0%
45.83%727.080813,01541.9%48.8%
44.78%676.479211,52944.8%44.7%
62.07%586.799613,99473.9%54.3%
50.00%546.992112,08943.3%58.3%
39.22%517.088613,35433.3%43.3%
40.82%496.674711,69523.8%53.6%
54.35%467.291112,93255.0%53.9%
48.84%436.780412,39344.4%52.0%
42.86%426.983511,61942.1%43.5%
59.52%427.086612,85426.7%77.8%
64.29%426.978811,43565.2%63.2%
52.38%427.095212,82152.6%52.2%
43.90%416.587011,26045.0%42.9%
47.50%406.999613,60450.0%45.8%
52.50%407.095113,76650.0%53.9%
55.56%367.080112,03360.0%45.5%
52.78%367.01,02013,39542.9%59.1%
47.22%366.882410,06640.9%57.1%
37.14%357.081310,77134.8%41.7%
54.55%337.291513,64766.7%47.6%
65.63%327.01,07214,11163.6%66.7%
58.06%317.41,02513,88564.7%50.0%
51.61%317.01,01113,79260.0%43.8%
37.93%296.980212,04841.7%35.3%
55.17%297.089312,26573.3%35.7%
60.00%257.187712,74645.5%71.4%
39.13%237.284011,86833.3%50.0%
61.90%217.31,01812,21066.7%58.3%
25.00%207.090211,53822.2%27.3%
40.00%207.692513,00642.9%38.5%
52.63%197.01,02813,4750.0%71.4%
55.56%186.998712,65533.3%66.7%
55.56%186.585012,49842.9%63.6%
70.59%177.81,20513,80077.8%62.5%
47.06%177.297513,92437.5%55.6%
56.25%167.796215,264100.0%36.4%
43.75%166.687113,10120.0%54.5%
62.50%167.296914,00777.8%42.9%
60.00%157.687813,43662.5%57.1%
60.00%156.986613,97880.0%50.0%
64.29%147.394113,07666.7%62.5%
50.00%146.889613,06783.3%25.0%
38.46%137.21,02312,79842.9%33.3%
53.85%137.187610,64962.5%40.0%
61.54%137.088414,04166.7%57.1%
50.00%127.194611,92566.7%33.3%
66.67%127.183612,79262.5%75.0%
55.56%96.899115,7870.0%71.4%
33.33%97.399211,99928.6%50.0%
37.50%86.81,03812,80040.0%33.3%
57.14%77.689013,21050.0%66.7%
42.86%75.881910,10640.0%50.0%
42.86%76.71,01311,89233.3%50.0%
66.67%67.08819,08450.0%100.0%
50.00%67.91,08615,078100.0%40.0%
83.33%65.790914,734100.0%80.0%
50.00%66.694412,37333.3%66.7%
50.00%67.082911,19750.0%50.0%
83.33%66.51,08015,590100.0%75.0%
66.67%67.71,03716,00250.0%75.0%
0.00%57.690213,6370.0%0.0%
80.00%56.484513,566100.0%66.7%
60.00%57.51,03214,08233.3%100.0%
60.00%57.395612,89766.7%50.0%
60.00%52.485211,91450.0%66.7%
40.00%57.069511,8570.0%66.7%

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Syndra vs Zoe - Frequently Asked Questions

How does Syndra do against Zoe in League of Legends?

Zoe wins the Syndra vs Zoe matchup with a 62.1% win rate compared to Syndra's 37.9%, a 24.1 percentage point difference. This data is based on 29 recent ranked games in patch 26.7.

How does Syndra do against Zoe in the early game?

In the early game, Zoe has the advantage against Syndra with a 58.3% win rate versus 41.7%. Zoe players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Zoe in the late game?

In the late game, Zoe takes over the Syndra vs Zoe matchup with a 64.7% win rate compared to 35.3%. Zoe scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Zoe matchup?

Zoe wins the matchup against Syndra with a 62.1% win rate in League of Legends patch 26.7. The 24.1 percentage point advantage means Zoe is significantly favored in this lane matchup based on 29 games analyzed.

What is the best Syndra build against Zoe?

The best Syndra build against Zoe includes Luden's Echo, Shadowflame, Rabadon's Deathcap with Spellslinger's Shoes. This build achieves a 20.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Zoe?

The best Syndra runes against Zoe use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Zoe matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Zoe?

No, Syndra struggles against Zoe with only a 37.9% win rate. Zoe has the advantage in this matchup. Syndra players should focus on safe farming and avoiding extended trades to minimize Zoe's lead.

How do I play Syndra against Zoe?

When playing Syndra against Zoe, play cautiously and avoid Zoe's power spikes. Look for jungle assistance and team-dependent plays since Zoe has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.