
Syndravs Kai'Sa
Syndra vs Kai'Sa is a decisive matchup in LoL patch 26.13. Syndra wins with a 66.7% win rate (+33.3%) over Kai'Sa based on 6 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Kai'Sa matchup.
Syndra Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Syndra vs Kai'Sa Matchup?

Syndra vs Kai'Sa Matchup Summary
The Syndra vs Kai'Sa matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Syndra wins with a 66.7% win rate compared to Kai'Sa's 33.3%, giving Syndra a 33.3 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Kai'Sa players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Syndra leads by 1.5s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra players can confidently pick into Kai'Sa and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Kai'Sa away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Syndra vs Kai'Sa Laning Phase Breakdown
Kai'Sa is favored during the laning phase against Syndra, winning 4 out of 5 key stat categories. Kai'Sa holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.
Best Syndra Build Against Kai'Sa
Crimson Lucidity is the optimal boots choice against Kai'Sa, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Kai'Sa are Cosmic Drive, Cryptbloom and Rabadon's Deathcap. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Kai'Sa. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Kai'Sa matchup.
Early Game vs Late Game
The early game (first 15 minutes) is a toss-up between Syndra and Kai'Sa, with Syndra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Syndra is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Kai'Sa. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.
Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Kai'Sa players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Syndra Runes Against Kai'Sa
Running Inspiration primary with Sorcery secondary allows Syndra to press their advantage against Kai'Sa, amplifying the strengths that make this a favorable matchup.
Syndra matchup data for League of Legends patch 26.13. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 51.95% | 77 | 6.7 | 924 | 12,706 | 54.8% | 50.0% | |
| 50.00% | 38 | 7.4 | 933 | 12,005 | 62.5% | 40.9% | |
| 54.29% | 35 | 6.8 | 858 | 12,376 | 64.3% | 47.6% | |
| 55.88% | 34 | 7.2 | 859 | 12,334 | 58.8% | 52.9% | |
| 37.93% | 29 | 6.6 | 1,028 | 13,098 | 53.9% | 25.0% | |
| 44.44% | 27 | 7.2 | 927 | 12,112 | 30.0% | 52.9% | |
| 53.85% | 26 | 7.1 | 803 | 12,154 | 45.5% | 60.0% | |
| 45.83% | 24 | 7.1 | 1,055 | 14,596 | 40.0% | 47.4% | |
| 54.17% | 24 | 6.7 | 874 | 11,100 | 38.5% | 72.7% | |
| 50.00% | 22 | 6.9 | 899 | 10,320 | 46.1% | 55.6% | |
| 52.38% | 21 | 7.1 | 1,011 | 12,585 | 62.5% | 46.1% | |
| 47.62% | 21 | 6.7 | 952 | 12,971 | 44.4% | 50.0% | |
| 50.00% | 20 | 7.0 | 813 | 13,616 | 57.1% | 46.1% | |
| 36.84% | 19 | 6.5 | 844 | 12,970 | 28.6% | 41.7% | |
| 44.44% | 18 | 7.3 | 932 | 12,400 | 62.5% | 30.0% | |
| 44.44% | 18 | 6.7 | 853 | 12,925 | 37.5% | 50.0% | |
| 37.50% | 16 | 7.7 | 1,063 | 12,864 | 100.0% | 16.7% | |
| 43.75% | 16 | 6.2 | 915 | 13,806 | 75.0% | 33.3% | |
| 50.00% | 14 | 6.8 | 968 | 12,910 | 42.9% | 57.1% | |
| 64.29% | 14 | 8.1 | 816 | 10,902 | 42.9% | 85.7% | |
| 38.46% | 13 | 6.8 | 787 | 10,425 | 50.0% | 28.6% | |
| 66.67% | 12 | 6.4 | 617 | 9,655 | 62.5% | 75.0% | |
| 75.00% | 12 | 6.5 | 1,085 | 13,629 | 80.0% | 71.4% | |
| 45.45% | 11 | 7.9 | 1,020 | 14,728 | 50.0% | 44.4% | |
| 63.64% | 11 | 7.8 | 860 | 12,410 | 71.4% | 50.0% | |
| 45.45% | 11 | 6.6 | 959 | 12,952 | 66.7% | 37.5% | |
| 45.45% | 11 | 7.1 | 1,089 | 14,298 | 60.0% | 33.3% | |
| 54.55% | 11 | 6.9 | 1,029 | 15,266 | 100.0% | 37.5% | |
| 40.00% | 10 | 6.5 | 848 | 11,922 | 33.3% | 50.0% | |
| 70.00% | 10 | 7.3 | 880 | 13,037 | 50.0% | 83.3% | |
| 55.56% | 9 | 6.2 | 1,076 | 14,003 | 66.7% | 50.0% | |
| 50.00% | 8 | 6.3 | 1,185 | 13,664 | 50.0% | 50.0% | |
| 37.50% | 8 | 6.0 | 788 | 14,905 | 66.7% | 20.0% | |
| 57.14% | 7 | 6.1 | 785 | 11,729 | 100.0% | 50.0% | |
| 14.29% | 7 | 7.2 | 829 | 13,649 | 0.0% | 20.0% | |
| 71.43% | 7 | 6.7 | 956 | 15,154 | 100.0% | 50.0% | |
| 28.57% | 7 | 5.8 | 778 | 11,760 | 33.3% | 25.0% | |
| 71.43% | 7 | 6.9 | 785 | 9,042 | 60.0% | 100.0% | |
| 28.57% | 7 | 7.5 | 999 | 15,375 | 0.0% | 40.0% | |
| 33.33% | 6 | 7.9 | 847 | 11,846 | 0.0% | 50.0% | |
| 66.67% | 6 | 6.7 | 922 | 13,630 | 50.0% | 75.0% | |
| 60.00% | 5 | 5.3 | 759 | 11,778 | 50.0% | 66.7% | |
| 80.00% | 5 | 6.5 | 917 | 14,228 | 100.0% | 75.0% | |
| 66.67% | 3 | 7.3 | 755 | 9,470 | 100.0% | 0.0% |
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Syndra vs Kai'Sa - Frequently Asked Questions
How does Syndra do against Kai'Sa in League of Legends?
Syndra wins the Syndra vs Kai'Sa matchup with a 66.7% win rate compared to Kai'Sa's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.13.
How does Syndra do against Kai'Sa in the early game?
In the early game, Syndra has the advantage against Kai'Sa with a 50.0% win rate versus 50.0%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Syndra do against Kai'Sa in the late game?
In the late game, Syndra takes over the Syndra vs Kai'Sa matchup with a 75.0% win rate compared to 25.0%. Syndra scales better into team fights and objective contests after 25 minutes.
Who wins the Syndra vs Kai'Sa matchup?
Syndra wins the matchup against Kai'Sa with a 66.7% win rate in League of Legends patch 26.13. The 33.3 percentage point advantage means Syndra is significantly favored in this lane matchup based on 6 games analyzed.
What is the best Syndra build against Kai'Sa?
The best Syndra build against Kai'Sa includes Cosmic Drive, Cryptbloom, Rabadon's Deathcap with Crimson Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Syndra runes against Kai'Sa?
The best Syndra runes against Kai'Sa use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Kai'Sa matchup. See the full rune breakdown in the matchup comparison above.
Does Syndra counter Kai'Sa?
Yes, Syndra has a favorable matchup against Kai'Sa with a 66.7% win rate. Syndra strongly counters Kai'Sa in lane based on current patch 26.13 data.
How do I play Syndra against Kai'Sa?
When playing Syndra against Kai'Sa, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
