Syndra - League of Legends Champion
Win Rate
50.3%
Pick Rate
1.8%

Syndravs Lissandra

BMage
Patch26.10
Matches2,379,056
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 25, 2026
MethodologyData Methodology

Syndra vs Lissandra is a decisive matchup in LoL patch 26.10. Syndra wins with a 54.4% win rate (+8.8%) over Lissandra based on 57 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Lissandra matchup.

Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 54.4% win rateLissandra(54.4%)
Syndra - 54.4% win rate in this matchup
Syndra
54.4% WR
VS
Lissandra vs Syndra matchup - 45.6% win rate
Lissandra
45.6% WR

Who Wins the Syndra vs Lissandra Matchup?

Syndra wins the Syndra vs Lissandra matchup
Winner
Syndra
Matches: 57
54.4%
Win Rate
45.6%
6.9
CS / min
6.6
943
DMG / min
742
12,618
Gold / game
11,414
79
Heal / min
142
316
DMG Mitigated / min
434
1.3
CC / min
1.4
52.2%
Early Game WR
47.8%
55.9%
Late Game WR
44.1%

Syndra vs Lissandra Matchup Summary

The Syndra vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 57 recent matches analyzed, Syndra wins with a 54.4% win rate compared to Lissandra's 45.6%, giving Syndra a 8.8 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Lissandra leads by 181 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Lissandra Laning Phase Breakdown

Syndra wins the laning phase against Lissandra in League of Legends

Syndra is favored during the laning phase against Lissandra, winning 3 out of 5 key stat categories. Syndra holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.9Syndra
6.6Lissandra
Syndra and Lissandra farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
943Syndra
742Lissandra
Syndra heavily out-damages Lissandra by 201 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
12,618Syndra
11,414Lissandra
Syndra generates a commanding 1,204 more gold per game than Lissandra. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.3Syndra
1.4Lissandra
Both Syndra and Lissandra provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
395Syndra
575Lissandra
Lissandra vastly out-sustains Syndra, healing and mitigating 181 more damage per minute. This massive durability gap means Lissandra can absorb significant punishment and remain in lane while Syndra is forced to recall. Building grievous wounds early is essential for Syndra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Syndra Build Against Lissandra

Spellslinger's Shoes is the optimal boots choice against Lissandra, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Lissandra are Luden's Echo, Shadowflame and Rabadon's Deathcap. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 66.7% win rate across 6 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Lissandra matchup.

Early Game vs Late Game

Early Game
Syndra
52.2%
+4.3% advantage
Syndra early game win rateSyndra52.2%
Lissandra early game win rateLissandra47.8%
Late Game
Syndra
55.9%
+11.8% advantage
Syndra late game win rateSyndra55.9%
Lissandra late game win rateLissandra44.1%

During the early laning phase (first 15 minutes), Syndra has a meaningful 52.2% win rate, outperforming Lissandra by 4.3 percentage points. Syndra players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

Syndra is far superior in the late game (25+ minutes), boasting a 55.9% win rate — 11.8 points above Lissandra. Extended games heavily favor Syndra, whose kit and scaling make them a dominant force in team fights and objective control.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Syndra Runes Against Lissandra

Inspiration rune tree - Syndra primary runes vs LissandraInspiration
First Strike - best Syndra rune vs LissandraMagical Footwear - best Syndra rune vs LissandraBiscuit Delivery - best Syndra rune vs LissandraCosmic Insight - best Syndra rune vs Lissandra
Sorcery rune tree - Syndra secondary runes vs LissandraSorcery
Manaflow Band - best Syndra rune vs LissandraTranscendence - best Syndra rune vs Lissandra
56.3% WR

Running Inspiration primary with Sorcery secondary allows Syndra to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Syndra matchup data for League of Legends patch 26.10. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
50.55%1827.294212,97042.1%56.6%
51.75%1437.186212,25457.6%46.8%
50.36%1396.885812,25547.5%52.5%
51.13%1337.190412,68554.5%48.7%
48.80%1256.583612,09144.2%51.2%
57.02%1146.684112,75950.0%61.8%
40.38%1046.998613,42548.5%36.6%
41.58%1016.781711,42738.6%43.9%
54.46%1016.788311,45844.4%62.5%
41.58%1016.579511,49843.5%40.0%
52.87%877.097612,06769.2%39.6%
39.24%796.782511,92234.2%43.9%
53.16%796.883711,65063.6%45.6%
50.00%786.594512,56530.3%64.4%
42.47%736.791912,32041.4%43.2%
50.70%716.790712,54054.5%47.4%
53.73%676.893212,25748.3%57.9%
43.75%646.678512,04737.5%47.5%
58.06%627.079912,15756.7%59.4%
54.24%597.493612,88056.0%52.9%
54.39%576.994312,61852.2%55.9%
59.65%577.295212,77682.6%44.1%
55.36%567.080010,42957.1%53.6%
50.00%546.889012,74454.2%46.7%
46.30%546.698313,82255.0%41.2%
45.28%536.496211,58142.9%48.0%
54.72%536.786610,96855.6%53.9%
58.00%507.097212,31761.9%55.2%
41.67%486.681112,58731.6%48.3%
50.00%486.691312,40538.9%56.7%
59.09%447.288812,48252.4%65.2%
65.91%446.994912,34955.0%75.0%
53.49%437.298212,90464.7%46.1%
76.32%387.21,01213,53183.3%70.0%
44.12%346.990212,38650.0%38.9%
50.00%346.583011,83537.5%61.1%
46.88%326.61,10913,52840.0%50.0%
53.13%326.988813,32666.7%45.0%
65.63%327.41,04313,32560.0%70.6%
48.39%317.382412,72271.4%29.4%
44.44%276.81,07412,28266.7%26.7%
48.00%256.789613,05860.0%45.0%
29.17%246.886813,9860.0%35.0%
54.17%247.297713,24260.0%50.0%
39.13%236.71,01913,12333.3%41.2%
40.91%226.896413,00823.1%66.7%
33.33%216.086210,86140.0%27.3%
63.16%197.398113,42650.0%72.7%
33.33%186.688611,84425.0%40.0%
55.56%186.996514,37857.1%54.5%
44.44%187.091513,15650.0%41.7%
52.94%176.394712,66766.7%45.5%
41.18%176.591215,03066.7%35.7%
70.59%176.281411,90671.4%70.0%
41.18%176.788014,15857.1%30.0%
50.00%167.697213,54012.5%87.5%
40.00%157.090710,83337.5%42.9%
40.00%157.378610,71540.0%40.0%
64.29%146.886711,36260.0%66.7%
53.85%136.998414,0490.0%70.0%
33.33%127.285312,86440.0%28.6%
41.67%126.81,00214,69375.0%25.0%
45.45%116.490511,85650.0%40.0%
33.33%96.57879,81940.0%25.0%
77.78%97.189013,28380.0%75.0%
66.67%96.891714,81050.0%80.0%
55.56%93.67139,84950.0%60.0%
66.67%96.785312,24375.0%60.0%
55.56%96.596112,90866.7%33.3%
55.56%96.899013,76425.0%80.0%
37.50%87.31,07613,02925.0%50.0%
62.50%83.395911,714100.0%50.0%
50.00%87.698615,911100.0%42.9%
37.50%87.81,26514,0980.0%42.9%
75.00%85.31,12213,48075.0%75.0%
57.14%77.31,22716,6560.0%66.7%
42.86%77.586015,7430.0%50.0%
42.86%77.196713,839100.0%33.3%
66.67%64.21,04513,564100.0%50.0%
33.33%67.387710,70650.0%0.0%
66.67%67.31,05116,11066.7%66.7%
66.67%64.266210,10150.0%75.0%
50.00%67.174712,53950.0%50.0%
83.33%67.01,10213,042100.0%66.7%
66.67%66.91,18312,90466.7%66.7%
60.00%56.01,08111,349100.0%50.0%
40.00%53.36917,86440.0%0.0%
60.00%55.192914,0650.0%75.0%
60.00%56.384510,31950.0%100.0%
80.00%56.31,12413,342100.0%75.0%
40.00%56.88069,11225.0%100.0%

Get the MetaBot Desktop App

Level up your gameplay with real-time overlays, automatic game detection, and instant stats — all on your desktop.

In-game overlaysAuto game detectionMulti-game supportPersonal dashboard
Download NowFree download
🔍

Help us maintain accuracy! If you notice incorrect stats, missing data, or any issues, your feedback directly improves the quality of our data for the entire community.

Report an Issue

Syndra vs Lissandra - Frequently Asked Questions

How does Syndra do against Lissandra in League of Legends?

Syndra wins the Syndra vs Lissandra matchup with a 54.4% win rate compared to Lissandra's 45.6%, a 8.8 percentage point difference. This data is based on 57 recent ranked games in patch 26.10.

How does Syndra do against Lissandra in the early game?

In the early game, Syndra has the advantage against Lissandra with a 52.2% win rate versus 47.8%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Lissandra in the late game?

In the late game, Syndra takes over the Syndra vs Lissandra matchup with a 55.9% win rate compared to 44.1%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Lissandra matchup?

Syndra wins the matchup against Lissandra with a 54.4% win rate in League of Legends patch 26.10. The 8.8 percentage point advantage means Syndra is significantly favored in this lane matchup based on 57 games analyzed.

What is the best Syndra build against Lissandra?

The best Syndra build against Lissandra includes Luden's Echo, Shadowflame, Rabadon's Deathcap with Spellslinger's Shoes. This build achieves a 66.7% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Lissandra?

The best Syndra runes against Lissandra use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 56.3% win rate in the Syndra vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Lissandra?

Yes, Syndra has a favorable matchup against Lissandra with a 54.4% win rate. Syndra strongly counters Lissandra in lane based on current patch 26.10 data.

How do I play Syndra against Lissandra?

When playing Syndra against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.