Syndra - League of Legends Champion
Win Rate
50.7%
Pick Rate
2.5%

Syndravs Lissandra

BMage
Patch26.13
Matches265,623
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 10, 2026
MethodologyData Methodology

Syndra vs Lissandra is a decisive matchup in LoL patch 26.13. Syndra wins with a 56.3% win rate (+12.5%) over Lissandra based on 16 games. Syndra holds the advantage in both the early and late game. Below you'll find the best Syndra build, runes, laning stats, and strategies for the Syndra vs Lissandra matchup.

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Syndra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Syndra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Syndra - 56.3% win rate in this matchup
Syndra
56.3% WR
VS
Lissandra vs Syndra matchup - 43.8% win rate
Lissandra
43.8% WR

Who Wins the Syndra vs Lissandra Matchup?

Syndra wins the Syndra vs Lissandra matchup
Winner
Syndra
Matches: 16
56.3%
Win Rate
43.8%
6.9
CS / min
6.3
1,004
DMG / min
661
13,509
Gold / game
11,043
70
Heal / min
135
330
DMG Mitigated / min
403
1.4
CC / min
1.3
62.5%
Early Game WR
37.5%
50.0%
Late Game WR
50.0%

Syndra vs Lissandra Matchup Summary

The Syndra vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 16 recent matches analyzed, Syndra wins with a 56.3% win rate compared to Lissandra's 43.8%, giving Syndra a 12.5 percentage point advantage. Syndra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Lissandra players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Syndra leads by 343 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Syndra players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Syndra vs Lissandra Laning Phase Breakdown

Syndra wins the laning phase against Lissandra in League of Legends

Syndra is favored during the laning phase against Lissandra, winning 4 out of 5 key stat categories. Syndra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
6.9Syndra
6.3Lissandra
Syndra edges out Lissandra by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Syndra.
Damage
1,004Syndra
661Lissandra
Syndra heavily out-damages Lissandra by 343 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Syndra's sustained damage advantage take over.
Economy
13,509Syndra
11,043Lissandra
Syndra generates a commanding 2,466 more gold per game than Lissandra. This substantial economic advantage means Syndra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.4Syndra
1.3Lissandra
Both Syndra and Lissandra provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
400Syndra
539Lissandra
Lissandra heals and mitigates 139 more damage per minute than Syndra, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Syndra.

Best Syndra Build Against Lissandra

Spellslinger's Shoes is the optimal boots choice against Lissandra, providing the mobility and stats Syndra needs most in this matchup. The top-performing core items for Syndra against Lissandra are Luden's Echo, Shadowflame and Rabadon's Deathcap. This combination gives Syndra an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Syndra vs Lissandra matchup.

Early Game vs Late Game

Early Game
Syndra
62.5%
+25.0% advantage
Syndra early game win rateSyndra62.5%
Lissandra early game win rateLissandra37.5%
Late Game
Syndra
50.0%
+0.0% advantage
Syndra late game win rateSyndra50.0%
Lissandra late game win rateLissandra50.0%

Syndra dominates the early game (first 15 minutes) with a commanding 62.5% win rate — a 25.0 percentage point lead over Lissandra. This lopsided early game means Syndra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Syndra at 50.0% win rate — only 0.0 points ahead of Lissandra. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Syndra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Lissandra players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Syndra Runes Against Lissandra

Inspiration rune tree - Syndra primary runes vs LissandraInspiration
First Strike - best Syndra rune vs LissandraCash Back - best Syndra rune vs LissandraTriple Tonic - best Syndra rune vs LissandraJack Of All Trades - best Syndra rune vs Lissandra
Sorcery rune tree - Syndra secondary runes vs LissandraSorcery
Manaflow Band - best Syndra rune vs LissandraTranscendence - best Syndra rune vs Lissandra
100.0% WR

Running Inspiration primary with Sorcery secondary allows Syndra to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Syndra matchup data for League of Legends patch 26.13. The table below shows Syndra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Syndra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Syndra matchup win rates and stats in League of Legends patch 26.13
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.42%1246.892612,40248.1%55.7%
48.39%627.394812,64358.3%42.1%
52.17%467.088112,98964.3%46.9%
56.82%447.093612,84060.0%54.2%
57.14%427.01,04714,84654.5%58.1%
40.00%406.798913,25252.9%30.4%
51.28%396.784011,37840.9%64.7%
47.37%387.188411,91150.0%45.5%
57.58%337.095012,45066.7%52.4%
57.58%337.179712,14260.0%55.6%
40.63%326.879212,04438.5%42.1%
51.61%316.891612,57057.1%47.1%
41.38%296.684612,73840.0%42.1%
55.17%297.291212,12564.3%46.7%
44.83%297.095513,13845.5%44.4%
44.83%296.78609,71338.9%54.5%
44.00%257.297212,50145.5%42.9%
37.50%246.488913,27950.0%33.3%
39.13%237.61,00412,46971.4%25.0%
65.22%237.879711,75258.3%72.7%
54.55%226.583611,47240.0%66.7%
57.89%196.41,06713,50066.7%53.9%
63.16%196.61,01913,03771.4%58.3%
50.00%186.895112,52466.7%41.7%
55.56%187.01,05013,73250.0%60.0%
41.18%177.286112,34625.0%55.6%
50.00%167.096913,69771.4%33.3%
56.25%166.91,00413,50962.5%50.0%
53.33%156.81,09512,90950.0%57.1%
46.67%157.41,10915,48150.0%46.1%
60.00%156.562410,02566.7%50.0%
69.23%137.795312,96071.4%66.7%
41.67%126.082615,24880.0%14.3%
63.64%117.381912,18750.0%71.4%
60.00%106.377811,51666.7%57.1%
80.00%106.798015,93875.0%83.3%
40.00%106.174312,26025.0%50.0%
44.44%97.71,17316,7410.0%57.1%
62.50%87.18219,77760.0%66.7%
75.00%86.896114,781100.0%60.0%
14.29%77.282913,6490.0%20.0%
71.43%76.81,00114,18950.0%80.0%
57.14%76.689111,419100.0%40.0%
42.86%76.290712,39966.7%25.0%
33.33%67.291112,48750.0%0.0%
50.00%65.682812,04650.0%50.0%
16.67%66.970412,2140.0%50.0%
83.33%67.099013,305100.0%50.0%
100.00%66.71,02513,254100.0%100.0%
60.00%56.91,18112,52966.7%50.0%
60.00%57.163610,15066.7%50.0%
40.00%57.36599,04066.7%0.0%
40.00%56.699810,62150.0%33.3%
60.00%57.51,0429,85550.0%100.0%
60.00%57.185517,5060.0%60.0%
80.00%56.672214,064100.0%75.0%

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Syndra vs Lissandra - Frequently Asked Questions

How does Syndra do against Lissandra in League of Legends?

Syndra wins the Syndra vs Lissandra matchup with a 56.3% win rate compared to Lissandra's 43.8%, a 12.5 percentage point difference. This data is based on 16 recent ranked games in patch 26.13.

How does Syndra do against Lissandra in the early game?

In the early game, Syndra has the advantage against Lissandra with a 62.5% win rate versus 37.5%. Syndra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Syndra do against Lissandra in the late game?

In the late game, Syndra takes over the Syndra vs Lissandra matchup with a 50.0% win rate compared to 50.0%. Syndra scales better into team fights and objective contests after 25 minutes.

Who wins the Syndra vs Lissandra matchup?

Syndra wins the matchup against Lissandra with a 56.3% win rate in League of Legends patch 26.13. The 12.5 percentage point advantage means Syndra is significantly favored in this lane matchup based on 16 games analyzed.

What is the best Syndra build against Lissandra?

The best Syndra build against Lissandra includes Luden's Echo, Shadowflame, Rabadon's Deathcap with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Syndra runes against Lissandra?

The best Syndra runes against Lissandra use the Inspiration primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Syndra vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Syndra counter Lissandra?

Yes, Syndra has a favorable matchup against Lissandra with a 56.3% win rate. Syndra strongly counters Lissandra in lane based on current patch 26.13 data.

How do I play Syndra against Lissandra?

When playing Syndra against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.